Yu no bɔt Mɛdula Tayrɔyd Kansa (MTC), we na wan kayn tayroyd kansa?

Yu go dɔn yɛri bɔt di tayroyd gland we tan lɛk bɔtaflay we de bifo yu nɛk. Sɔntɛnde yu kin fil smɔl smɔl tin na dis gland. Ɔ dɔktɔ kin si am we yu de chɛk yu. Pan ɔl we dis lump nɔ kin denja, i kin bi sayn fɔ kansa. Tide, wi go tɔk bɔt wan spɛshal, bɔt sɔm kayn kansa we nɔ kin apin so ɔltɛm, we kin apin na di tayroyd gland.

Wetin na di mɛdula tayroyd kansa (MTC)?

Fɔ tɔk am simpul wan, Mɛdula Tayrɔyd Kansa (MTC) na kansa we de divɛlɔp insay yu tayroyd gland. di insay pat pan dis gland dεn kכl am di ‘mεdula’ . wan spεshal kayn sεl de insay dis mεdula, we dεn kכl ‘parafollicular C cells’ . dis C sεl dεm de mek di כmon ‘calcitonin’ . so, we dεn C sεl dεm ya bigin fכ gro we dεn nכ kכntrol, MTC de apin. Tink bɔt am lɛk plant dɛn we yu nɔ want na gadin we de skata ɔlsay we dɛn nɔ ebul fɔ kɔntrol.

Na nɔmal tin fɔ gɛt bɔku kwɛstyɔn ɛn fred we yu yɛri bɔt kansa, mɔ if na wan kayn we we nɔ kin bɔku. Bɔt mɛmba se yu mɛdikal tim de wit yu pan dis waka. Bɔku difrɛn we dɛn de fɔ trit MTC.

Aw kɔmɔn tin na mɛdula tayroyd kansa (MTC)?

Naw yu kin de tink se, "O, dis na sik we ɔlman kin gɛt?" Nɔ wɔri. Tayrɔyd kansa kin rili bɔku. Bɔt di kayn we we wi de tɔk bɔt , we na mɛdula tayroyd kansa (MTC) , nɔ kin bɔku . Ivin na kɔntri lɛk Amɛrika, na 4% to 10% nɔmɔ pan ɔl di tayroyd kansa dɛn we dɛn ripɔt, dɛn kin no se na MTC. Dat min se na lɛk 1,000 pipul dɛn nɔmɔ dɛn kin no se gɛt MTC de ɛvri ia. So, na Sri Lanka, dis nɔmba kin ivin smɔl pas dat.

Wetin na di sayn dɛm fɔ mɛdula tayroyd kansa (MTC)?

Okay, so wetin na di simptom dɛm fɔ MTC? Nɔto ɔlman kin gɛt di sem kayn sik. Bɔt sɔm tin dɛn de we kɔmɔn:

• wan lump (nodule) we de na di tכp pat pan yu tayroyd gland de palp. Dis na di men sayn wae kin apun pan 75% to 95% pan pipul dεm wae dεn no se dεn gεt dis sik. I kin fil lɛk smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl.
• Di limf no dɛm we dɔn swel na di nɛk . Dis kin si bak pan lɛk 70% pan pipul dɛm wae dɛn no di sik. Dɛn kin fil dɛn tin ya lɛk smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl.

Bɔt nɔto ɔltɛm, if di tayroyd nodul big, dɛn sayn ya kin apin:

• Voys chenj, hoarseness.
• I nɔ izi fɔ swɛla it.
• I nɔ kin izi fɔ yu fɔ blo.

De impɔtant tin na dat sɔm pipul kin gɛt MTC bɔt nɔr kin sho ɛni sayn fɔ lɔng tɛm. Dis na bikɔs di tumbu gɛt kansa.I rili smɔl. So, if yu notis ɛnitin we nɔ kɔmɔn na yu nɛk, i rili impɔtant fɔ pe atɛnshɔn to am.

Wetin mek di mɛdula tayroyd kansa (MTC) kin kam?

Naw lɛ wi luk wetin mek dis MTC de apin. Bɔku rizin dɛn de fɔ dis. Men wan, tu we de we MTC kin apin.

Sporadik MTC we de apin

Na lɛk 75% (lɛk tri pan 4) pan di wan dɛn we gɛt MTC kin gɛt dis sik wan wan tɛm . Dis min se nɔbɔdi na dɛn famili nɔ bin dɔn gɛt MTC bifo. I kin apin we yu nɔ gɛt famili istri. Sayɛnsman dɛn nɔ dɔn fɛn yet di rayt tin we mek dis MTC we kin apin wan wan tɛm. כltu, bitwin 40% εn 50% pan di pipul dεm we de divεlכp MTC dis we ya gεt mכtεshכn insay wan jin we dεn kכl ``(RET)`` . Dis nɔto sɔntin we dɛn bɔn wit, bɔt na tin we nɔr de na dɛn jɛnɛtiks we kin kam leta na layf.

MTC frɔm jɛnɛreshɔn to jɛnɛreshɔn

na di כda say, lεk 25% pan di MTC pasεnshכn dεm (lεk wan pan fכ) kin gεt wan kכndyushכn we dεn kin gεt we dεn kכl ‘Multiple Endocrine Neoplasia type 2’ (MEN2) . difrεn sכbtayp dεm de fכ 'MEN2':

• `(MEN2A)`: Pipul wae gɛt dis sik kin gɛt bɔrku risk fɔ gɛt MTC (lɛk 90%) .
• `(MEN2B)`: Sɔm kes dɛm fɔ `(MEN2B)` na ɛritayt. Bɔt bɔku tɛm dis nɔ kin bi. Pipul wae gɛt `(MEN2B)` gɛt 100% chans fɔ gɛt MTC we dɛn rili yɔŋ .

כda sכbtayp de fכ dis `(MEN2B)`, we dεn kכl `Familial Mεdula Tayroyd Kεnsar (FMTC) . Pipul dεm we gεt `(FMTC)` gεt `(RET)` jin mכtεshכn, bכt dεn nכ de divεlכp MTC (εn nכto כda kayn kεnsar).

Imajin, if dεn fכnshכn se pכsin na yu famili gεt dis ``(RET)`` jin mכtεshכn, yu kin ebul fכ avכyd big risk bay we dεn pul di tayroyd gland tru prεvεntiv כpεraysh כn bifo kεnsar kam.

Aw dɛn kin no se pɔsin gɛt mɛdula tayroyd kansa (MTC)?

Bɔku tɛm, MTC kin fɔs apia lɛk wan lump na di tayroyd gland. Yu kin fil am yusɛf, ɔ yu dɔktɔ kin fɛn am we yu fil yu nɛk we yu de du ɛgzam ɔltɛm. Sɔntɛnde, dɛn kin si di lump wan wan we dɛn de du imej tɛst fɔ ɔda rizin.

If yu dɔktɔ sɔprayz se yu gɛt MTC, i go mɔs bi se dɛn go ɔda dɛn tɛst ya:

• Imej tɛst: Dɛn tin ya kin ɛp fɔ si di tayroyd nodul klia wan. Fɔ ɛgzampul , wan tayroyd ɔltrasɔund , CT skan , ɛn/ɔ MRI.Yu kin du tɛst dɛn lɛk dis. Jɔs lɛk we pɔsin tek foto wit kamɛra, dɛn mashin dɛn ya kin si klia wan wetin de insay di bɔdi.
• Fayn nidul aspireshɔn (nidul bayɔpsi): Yu dɔktɔ go mɔs se yu fɔ tek smɔl sampul pan di tisu (bayopsi) frɔm yu tayroyd nodul. Dis min se yu fɔ yuz wan nidul we rili fayn. I kin tan lɛk se na smɔl nidul prɛk. afta dat dεn kin egzamin dis tisu sεmpl כnda maykroskכp fכ si if εni kεnsar sεl dεm de.
• Blɔd tɛst: Dɛn tɛst ya kin inklud tɛst fɔ no di lɛvɛl we di tin dɛn we de na yu blɔd we dɛn kɔl calcitonin ɛn carcinoembryonic antigen (CEA) . Dɛn lɛvɛl ya kin ɔltɛm go ɔp pan pipul dɛm wae gɛt MTC.

Yu dכkta kin rεkomεnd bak fכ du jεnεtik tεst fכ si if yu gεt jεnεtik kכndyushכn we dεn kכl ``MEN2''. If na so, dɛn kin se dɛn fɔ tɛst ɔda fambul dɛn we gɛt blɔd in jɛnɛtiks, bikɔs dis kin ɛp fɔ no if dɛn de pan denja.

Wetin na di tritmɛnt fɔ mɛdula tayroyd kansa (MTC)?

Okay, naw lɛ wi si us tritmɛnt dɛn de fɔ MTC.

Di men tritmɛnt fɔ MTC na ɔpreshɔn fɔ pul yu ɔl tayroyd gland (total thyroidectomy) . Pan ɔl we dis kin tan lɛk big ɔpreshɔn, na di bɛst we fɔ mɛn dis kansa.

• Fɔ pul di limf no dɛm: If tayroyd kansa dɔn skata (metastasized) to di limf no dɛm na yu nɛk, i go mɔs bi se di dɔktɔ we de du di ɔpreshɔn go pul dɛn bak.
• Ɔmon tɛrapi: Afta dɛn dɔn ɔpreshɔn yu, yu go nid fɔ tek mɛrɛsin fɔ tek di tayroyd ɔmon fɔ di res ɔf yu layf. Bikɔs di ɔmon dɛn we di tayroyd gland de mek impɔtant fɔ di bɔdi, dɛn nid fɔ gi dɛn na do lɛk pils.

Apat frɔm di ɔpreshɔn, yu dɔktɔ kin tɛl yu fɔ du ɔda tritmɛnt dɛn, lɛk:

• Radiation therapy: Na we fɔ pwɛl di kansa sɛl dɛn we dɛn de yuz ay ɛnaji rayt.
• Kimotɛrapi: Na we fɔ yuz drɔgs fɔ kil kansa sɛl dɛn.
• Targeted therapies: Insay sɔm kes dɛm fɔ MTC, dɛn kin yuz spɛshal drɔgs we de target ɔl di chenj dɛm na DNA . Sɔm ɛgzampul dɛn na vandetanib ɛn kabozantinib .

Afta yu dɔn gɛt tritmɛnt fɔ MTC, yu dɔktɔ go de chɛk yu CEA ɛn Calcitonin lɛvɛl ɔltɛm tru blɔd tɛst. Dis go ɛp dɛn fɔ no aw di tritmɛnt de wok fayn ɛn if di kansa dɔn kam bak.

MTC na kansa wae kin agresiv smɔl pas ɔda, mɔr kɔmɔn kayn tayroyd kansa. Bɔt if dɛn fɛn am bifo i go na di limf no dɛm na di nɛk ɔ ɔda pat dɛm na di bɔdi, i go izi fɔ trit, mɛn, ɛn kɔntrol am.

Wetin na di prɔgnosis fɔ pɔsin we gɛt mɛdula tayroyd kansa (MTC)?

Di prɔgnosis, ɔ aw pɔrsin kin si, fɔ pɔrsin wae gɛt MTC kin dipen pan sɔm tin dɛm.

• Di stej we di kansa de (dat na aw fa di kansa dɔn skata).
• If di kansa dɔn skata (metastasized) to ɔda pat dɛn na di bɔdi.
• Aw bɔku pan di kansa lump bin kɔmɔt we dɛn bin de du di ɔpreshɔn.
• Yu ej ɛn ɔl yu wɛlbɔdi.

di prכgnosis fכ MTC jεnarali nכ kin gud lεk fכ papillary tayroyd kεnsar εn fכlikul tayroyd kεnsar . Bɔt if yu ɛn yu dɔktɔ kech MTC kwik, i kin wɛl ɔl if yu du ɔpreshɔn . Ivin if di diagnosis let, MTC kin skata (i kin wɔs) smɔl smɔl .

De chans fɔ wɛl kin smɔl smɔl fɔ pipul dɛm lɛk dis:

• Pipul dɛn we dɔn pas 65 ia.
• Pipul dɛn we de na di advans stej fɔ gɛt kansa.
• Di wan dɛn we dɛn nɔ bin ebul fɔ pul dɛn kansa kpatakpata we dɛn bin de du di ɔpreshɔn.

Wetin na di layf we pɔsin kin gɛt we i gɛt mɛdula tayroyd kansa (MTC)?

We i kam pan di rεt wae pɔrsin wae gɛt MTC de liv, di risach wae de naw sho se di fayv ia rεt wae de liv fɔ stej wan, tu, ɛn tri pan MTC na lɛk 93%. כltu, fכ stej fכ, dis rεt de dכn to 28%.

Bɔt di impɔtant tin ya na dat bikɔs na smɔl nyu kes dɛm fɔ MTC dɛn kin ripɔt ɛvri ia, dɛn sɔvayv rɛt ya nɔ kin rili kɔrɛkt. Yu mɛdikal tim go gi yu bɛtɛ aidia bɔt wetin fɔ ɛkspɛkt.

Wetin na di difrɛns bitwin papillary ɛn medullary tayroyd kansa?

Naw yu go mɔs de wɔnda, ‘Wetin difrɛn bitwin dis MTC ɛn dɛn ɔda tayroyd kansa dɛn de?’

Papillary thyroid cancer na di kayn tayroyd kansa we kin bɔku pas ɔl . I de mek 80% pan di wan dɛn we dɛn kin no bɔt tayroyd kansa. Bɔt, mɛdula tayroyd kansa (MTC) nɔ kin bɔku .

Di men difrɛns de na di sɛl dɛn we dɛn tu kayn kansa ya kin bigin frɔm.

• di papilari tayroyd kansa de stat na di fכlikul sεl dεm na yu tayroyd gland we de mek tayroglobulin, we na wan protin.
• MTC de divεlכp frכm di C sεl dεm na di tayroyd gland we de prodyuz kalsitonin, we na כmon.

Wan ɔda tin na dat, bɔku tɛm, papillary thyroid cancer kin gɛt fɔ du wit redyushɔn, bɔt nɔto so klia link de wit MTC.

Fɔ dɔn, mɛmba dis.

Fɔ yɛri se yu gɛt kansa, ilɛk us kayn, na tin we de mek yu fred bad bad wan. Wi ɔl no dat. Bɔt we i kam pan mɛdula tayroyd kansa (MTC) , mɛmba se i kin ansa fayn to tritmɛnt if dɛn no am kwik .

Pan ɔl we wi nɔ no di rayt tin we kin mek bɔku pipul dɛn gɛt MTC, strɔng link de fɔ sɔm kayn tin dɛn we pɔsin kin gɛt frɔm in mama ɛn papa. So, if yu ɔ yu fambul we de nia yu (fɔs digri fambul - mama ɛn papa, brɔda ɛn sista, pikin dɛn) dɔn gɛt MTC, i rili impɔtant fɔ mek dɛn du jenɛtik tɛst. Dis kin rili ɛp yu ɛn yu famili.

If yu gɛt ɛni kwɛstyɔn bɔt yu risk fɔ gɛt MTC, nɔ fred fɔ tɔk to yu dɔktɔ. Dɛn de de ɔltɛm fɔ ɛp yu ɛn ansa yu kwɛstyɔn dɛn. Di tin we impɔtant pas ɔl na fɔ no bɔt sɔntin, fɔ no bɔt sɔntin, ɛn fɔ du di tin dɛn we yu nid fɔ du.

` Mεdula tayroyd kansa, MTC, tayroyd gland, kansa simptom dεm, jεnεtik tεst, MEN2, tayroyd כpεrayshכn