Yu no bɔt dis imejensi we kin apin to di lɔng dɛn afta yu dɔn gi blɔd? (TRALI) we dɛn kɔl

Yu dɔn ɛva gɛt blɔd transfyushɔn? Ɔ pɔsin we yu sabi dɔn ɛva gɛt am? Bɔku tɛm, fɔ gi blɔd na sɔntin we de ɛp fɔ sev pɔsin in layf. Bɔt na smɔl tɛm nɔmɔ, dat na, na smɔl tɛm nɔmɔ, sɔm pipul dɛn kin gɛt imejensi wɛlbɔdi prɔblɛm bikɔs ɔf dis blɔd we dɛn kin gi. Dis na wan pan dɛn kɔndishɔn we wi go tɔk bɔt tide, we dɛn kɔl TRALI. Dis nem kin bi nyu tin to yu, bɔt i rili impɔtant fɔ no bɔt am.

Wetin na (TRALI)? Lɛ wi ɔndastand am simpul wan

Fɔ tɔk am simpul wan, (TRALI) – we tinap fɔ Transfusion-Related Acute Lung Injury – na imejensi kɔndishɔn we kin afɛkt yu lɔng, ɔ we yu gɛt blɔd transfyushɔn ɔ insay 6 awa afta yu gɛt am. Wi lɔng dɛn gɛt smɔl smɔl ɛya sak dɛn, lɛk smɔl smɔl bɔl dɛn we tan lɛk grep. Wi kin kɔl dɛn tin ya bay mɛrɛsin (alveoli) . wεl, wetin de apin na dis (TRALI) kכndishכn na we wan kayn wata de fulכp insay dεn wan dεm (alveoli).

Tink bɔt am, lɛk spɔnj we de tek wata, wetin kin apin we dɛn ay sak dɛn ya ful-ɔp wit wata? I kin at fɔ blo, nɔto so? Di lɔng dɛn kin stɔp fɔ wok fayn fayn wan. Nɔto dat nɔmɔ, bɔt yu blɔd prɛshɔn kin go dɔŋ bak bad bad wan. Dis na rili siriɔs, mɛdikal imejensi . So if sɔntin lɛk dis apin, i rili impɔtant fɔ go to dɔktɔ wantɛm wantɛm.

Wetin na di sayn dɛm fɔ (TRALI)? Aw yu no am?

So, aw dis (TRALI) kɔndishɔn de fil? Wetin na di sayn dɛm we de sho se yu gɛt dis sik? Lɛ wi no bɔt dɛn tin ya bak.

• Yu kin fil fɔ blo shɔt ɔ yu kin fil at fɔ blo (dyspnea) . I kin tan lɛk se yu de blo fɔ blo afta yu dɔn klaym wan stej, ɔ lɛk se yu chɛst dɔn kɔnstrikt.
• Wan kɔf kin bigin wantɛm wantɛm .
• Sɔntɛnde yu skin, yu lip, ɛn yu finga nel dɛn kin tɔn blu (cyanosis) . Dis kin apin bikɔs di blɔd na yu bɔdi nɔ de gɛt inof ɔksijɛn. Dis na sayn we de mek pɔsin fred smɔl.
• Yu kin gɛt fiva , ɛn yu kin ivin fil lɛk se yu gɛt kol.
• Yu kin fil lɛk se yu ed de tɔn ɔ yu nɔ gɛt bɛtɛ ed .
• Sɔm pipul dɛn kin ivin fɔdɔm . Dis kin apin bikɔs dɛn blɔd prɛshɔn kin go dɔŋ tumɔs.

Dɛn sayn ya kin bigin we dɛn de gi blɔd ɔ insay 6 awa afta dɛn dɔn dɔn. So, i impɔtant fɔ tek tɛm bad bad wan insay dis tɛm. If yu ɔ pɔsin we yu sabi na pɔsin we de gi blɔd, i impɔtant fɔ no bɔt dɛn sik ya.

Wetin mek dis (TRALI) de apin? Wetin na di rizin?

Okay, naw mek wi si wai dis (TRALI) tin de hapun. Dis na smɔl sayɛns, bɔt a go ɛksplen am simpul wan so dat yu go ɔndastand.

Wi bɔdi gɛt wan imyun sistɛm. Na wetin de protɛkt wi frɔm sik. dis sistεm gεt spεshal pat dεm lεk ‘sכlda dεm’ we dεn k כl antibodi dεm.Dɛn men wok na fɔ protɛkt wi bay we dɛn de no ɛn fɛt bad bad tin dɛn lɛk jem ɛn vayrɔs we de kɔmɔt na do na di bɔdi.

Naw, we yu gɛt blɔd, sɔm pan di antibodi dɛn we de na di pɔsin we gi yu blɔd kin tay pan sɛl dɛn we dɛn kɔl wayt blɔd sɛl na yu bɔdi, mɔ na yu lɔng. Dis kin apin bay mistek. Dɔn yu imyun sistɛm de tink se, "O, sɔntin bad dɔn kam insay yu bɔdi, ɛnimi dɔn kam insay!" So, da sistɛm de kin bigin fɔ wok wantɛm wantɛm ɛn mek pɔsin gɛt inflamɛns . Dis inflamɛns na in kin mek di smɔl smɔl blɔd vesel dɛn na yu lɔng, di alvɔlɔs we a bin dɔn tɔk bɔt, kin pwɛl, ɛn wata kin lik insay di lɔng. I tan lɛk se wi yon difens sistɛm de ambɔg wi we wi nɔ no. I kɔmplikt smɔl, bɔt yu gɛt di aidia, nɔto so?

Udat de pan ay risk fɔ divɛlɔp (TRALI)?

Pan ɔl we dis sik (TRALI) kin apin to ɛnibɔdi we dɛn transfyuz blɔd, sɔm pipul dɛn kin gɛt am mɔ. Lɛ wi tek wan luk pan udat dɛn bi:

• Pipul dεm we kכnekt to atifishal rεspiratכr (mεkanikal ventilashכn). Dat min se, di wan dɛn we gɛt ɛp fɔ blo frɔm mashin na ɔspitul bikɔs i nɔ kin izi fɔ dɛn fɔ blo fɔ dɛnsɛf.
• Pipul wae gɛt siriɔs adikshɔn to rɔm (alcohol use disorder). Bikɔs if pɔsin drink pasmak, dat kin mek difrɛn difrɛn tin dɛn we de na di bɔdi wik.
• Pipul dɛn we kin yuz tabak bɔku tɛm. Dat min tin dɛn lɛk sigrɛt ɛn bidis. Wi no se fɔ smok kin ambɔg di lɔng dɛn.
• Pipul wae dɔn ɔlrɛdi gɛt liva ɔ kidni sik. We dɛn ɔgan dɛn ya nɔ de wok fayn, di bɔdi in balans kin ambɔg.
• Patient dɛm wae dɔn ɔlrɛdi sik bad bad wan. Fɔ ɛgzampul, di wan dɛn we gɛt bad bad sik, lɛk di wan dɛn we dɛn dɔn du ɔpreshɔn.
• Dis risk kin bכku bak pan pipul dεm we de gεt bכku bכku bכku bכku bכku wan wan כ dεn wan dεm we de gεt spεshal bכdi prodakt dεm (e.g., plasma, pletlet) .

Dɛn tin ya nɔ min se yu go mɔs gɛt TRALI if yu de pan dis grup, bɔt dɛn min se di risk go bɔku smɔl.

Aw dɔktɔ dɛn kin no if pɔsin gɛt TRALI? (Diagnosis) .

Aw dɔktɔ kin no se i gɛt TRALI? Dis kin tranga smɔl, bikɔs di sayn dɛm kin tan lɛk ɔda prɔblɛm dɛm na di lɔng.

Fɔs, dɛn go tray fɔ pul ɔda tin dɛn we go de mek yu gɛt di sik, fɔ ɛgzampul, wan bad bad alɛji (anaphylaxis) , yu pulmonary edema bikɔs yu at nɔ de wok fayn, ɔ yu gɛt siriɔs infɛkshɔn . Fɔ du dis, dɛn go:

• Wi go tek tɛm aks bɔt yu mɛdikal istri ɛn di blɔd we yu jɔs gi.
• Dɛn kin du wan ɛgzam pan pɔsin in bɔdi .
• Dɛn kin du bɔku blɔd tɛst dɛn. Dɛn tin ya kin chɛk tin dɛn lɛk di ɔksijɛn lɛvɛl ɛn di infɛkshɔn stetɔs.
• Dɛn kin du imej tɛst pan di chɛst . Bɔku tɛm, dis kin gɛt fɔ du wit ɛkstrem rayt na in chɛst . insay di kes fכ TRALI, dis kin sho klia wan di wata we de fulכp di tu lכng dεm. Sɔntɛnde, dɛn kin du CT skan bak. Lan mɔ.
• Yu kin gɛt at skan bak we dɛn kɔl ɛkokadiogram fɔ si aw yu at de wok fayn fayn wan. Dis kin ɛp fɔ pul di prɔblɛm dɛn we de na di lɔng we kin kam bikɔs di at de wok.

Afta dɛn dɔn du ɔl dis, di dɔktɔ dɛn kin kam fɔ no se na (TRALI).

Wetin na di tritmɛnt dɛm fɔ (TRALI)?

Na ɔnfɔni, nɔr patikyula ‘cure’ nɔr de fɔ dis kɔndishɔn (TRALI), we min se nɔr mɛrɛsin nɔr de we go ebul fɔ mɛn am kɔmplit wan yet. Bɔt, nɔ fred. Dɔktɔ dɛn kin mek yu stebul ɛn kia fɔ yu gud gud wan te di sik bɛtɛ fɔ insɛf. Dɛn kɔl dis sɔpɔtiv kia . Dɛn kin gi yu tritmɛnt dɛn lɛk:

• Ɔksijɛn tɛrapi: Dɛn kin gi ɔksijɛn tru mask ɔ nasal kanula fɔ ɛp fɔ blo ɛn gi di bɔdi di ɔksijɛn we i nid.
• Vasopressors: Dis na mɛrɛsin dɛn we dɛn kin gi fɔ mek di blɔd prɛshɔn we de dɔŋ kam bak to nɔmal. Dɛn kin gi dɛn tin ya insay di bɛlɛ.
• Diuretics ɔ IV fluid: Dipen pan yu kɔndishɔn, dɛn kin gi yu diuretics (mɛrɛsin we de mek yu lɔs wata tru urine) fɔ ridyus di wata we pasmak na yu lɔng ɛn bɔdi. Ɔ if nid de, dɛn kin gi IV wata fɔ mek dɛn kɔntinyu fɔ gɛt blɔd prɛshɔn. Na dɔktɔ kin disayd dis.
• Mekanikal ventileshɔn: If i rili at fɔ blo ɛn yu nɔ ebul fɔ blo fayn fɔ yusɛf, yu kin nid fɔ gi yu mashin we yu de blo as we fɔ sev yu layf. Insay dis, dɛn kin put wan tiub insay di briz ɛn wan mashin kin kɔntrol di we aw pɔsin de blo.

Wit dis tritmɛnt, bɔrku pasɛnt dɛn kɔndishɔn kin bɛtɛ smɔl smɔl.

Wetin fɔ ɛkspɛkt if yu divɛlɔp (TRALI)?

Wetin go apin if yu gɛt TRALI? Dis na impɔtant tin bak fɔ no.

Bɔku tɛm, TRALI kin bɛtɛ insay tu to 4 dez . Fɔ sɔm pipul dɛm, e kin tek smɔl tɛm, i kin dipen pan aw de sik tranga ɛn yu ɔl gɛt wɛl bɔdi. Insay da tɛm de, dɔktɔ ɛn nɔs dɛn go kip yu na ɔspitul, bɔku tɛm na di intensiv kia yunit (ICU), ɛn dɛn go de wach yu ɔltɛm (we yu de blo, ɔksijɛn lɛvɛl, blɔd prɛshɔn) ɛn gi yu sɔpɔt kia. Dis min se dɛn go du dɛn bɛst fɔ kɔntrol yu sik dɛn ɛn mek ɔda prɔblɛm dɛn nɔ kam.

Ustɛm yu fɔ go na di Imejɛnsi Tritmɛnt Yunit (ETU) ?

Dis na sɔntin we yu fɔ rili mɛmba. Afta yu dɔn gi blɔd:

• I nɔ kin izi fɔ yu fɔ blo wantɛm wantɛm
• Chɛst de pen ɔ tayt
• Kɔf bad bad wan
• Fiva
• Diziz, blurred vishɔn
• Bluish diskɔlɔreshɔn na di skin ɛn di lip dɛn

If yu gɛt ɛni wan pan dɛn sik ya ɔ ɛni ɔda tin we nɔ kɔmɔn, go to di Imejɛnsi Dipatmɛnt (ETU) we de nia yu wantɛm wantɛm, ɔ if yu de na ɔspitul, tɛl di mɛdikal tim wantɛm wantɛm. Nɔ west tɛm. Dis na impɔtant tin, bikɔs fɔ asɛs ɛn trit am kwik kwik wan kin sev pɔsin in layf.

Yu tink se dɛn kin ebul fɔ stɔp TRALI?

"Dɛn nɔ go ebul fɔ stɔp dis?" yu kin de wɔnda. Infakt, naw, no we nɔ de fɔ mek dɛn nɔ gɛt TRALI kpatakpata. Bɔt di wan dɛn we de gi blɔd ɛn ɔspitul dɛn de du ɔl wetin dɛn ebul fɔ chɛk di blɔd we dɛn gi, mɔ di wan dɛn we gɛt sɔm kayn antibodi dɛn, fɔ mek dɛn nɔ gɛt prɔblɛm wit di blɔd transfyushɔn. Fɔ ɛgzampul, dɛn de pe mɔ atɛnshɔn to di yus fɔ plasma frɔm uman dɛn we dɔn gɛt bɛlɛ bifo, bikɔs dɛn kin gɛt dɛn antibodi ya na dɛn blɔd.

Infakt, i kin mek wi fred fɔ tink se sɔntin we gud go apin bad to wi, nɔto so? Bɔt fɔ gi blɔd na tin we pipul dɛn kin du fɔ mɛn pipul dɛn we kin sev bɔku pipul dɛn layf ɔlsay na di wɔl. Transfyushɔn riakshɔn lɛk (TRALI) nɔ kin bɔku. Bɔt if dɛn apin, dɛn kin mek pɔsin in layf de pan denja. So, if yu fil ɛnitin we nɔ kɔmɔn afta yu dɔn gi yu blɔd, go to dɔktɔ ɛn nɔ shem. Di tin we impɔtant pas ɔl na fɔ gɛt tritmɛnt kwik kwik wan.

Wetin na di tin dɛn we wi fɔ mɛmba frɔm dis stori?

Okay, so, fɔ sɔma, di men pɔynt dɛn fɔ mɛmba bɔt TRALI we wi tɔk bɔt na dɛn wan ya:

• (TRALI) na siriɔs sik we kin apin wantɛm wantɛm (bɔku tɛm insay 6 awa) afta dɛn dɔn transfyu am blɔd, we kin mek i nɔ izi fɔ blo ɛn blɔd prɛshɔn kin smɔl bikɔs wata kin bɔku na di lɔng dɛn.
• Sɔm kayn sik lɛk fɔ blo shɔt, kɔf, blu skin, fiva, ɛn diziz kin apin. Yu fɔ no bɔt dɛn tin ya.
• Bɔku tɛm dis kin apin we di antibodi dɛn we de na di pɔsin in blɔd kin mek di pɔsin in imyun sistɛm mistek fɔ mek di lɔng dɛn wok ɛn pwɛl.
• Sɔm pipul dɛm (e.g., di wan dɛm wae de pan ventilator, di wan dɛm wae gɛt liva/kidni sik, ɛn di wan dɛm wae de drink bɔrku) kin gɛt dis kayn risk.
• Dis na mɛdikal imejensi. I impɔtant fɔ go to dɔktɔ wantɛm wantɛm if yu gɛt di sik.
• Pan ɔl we no patikyula mɛrɛsin nɔ de fɔ TRALI, bɔku pipul dɛn kin wɛl insay sɔm dez wit sɔpɔt kia we dɛn kin gi na di ɔspitul.
• Pan ɔl we TRALI na wan sik we nɔ kin apin so ɔltɛm , i impɔtant fɔ no bɔt am ɛn no di sayn dɛm.

Yu sabi yu bɔdi pas ɔlman. If yu fil ɛnitin we strenj, difrɛn, ɔ we nɔ fayn afta yu dɔn gi blɔd, nɔ dismis am as ‘smɔl tin.’ Nɔ tek am layt. Tɛl dɔktɔ wantɛm wantɛm. I kin sev yu layf! Stay wit wɛlbɔdi!

` Blɔd gi, lɔng, prɔblɛm fɔ blo, TRALI, blɔd transfyushɔn, antibodi, imejensi kia