Owulira ng’oli munafu? Ebitundu byo eby’omubiri biwunya? Ka tuyige ku bulwadde bwa CIDP (Chronic Inflammatory Demyelinating Polyneuropathy)!

Oluusi owulira ng’okooye nnyo, emikono n’amagulu bikuzibye oba ng’olina ekiwujjo? Oluusi oyinza obutafaayo nnyo ku bintu bino. Kyokka, mu mbeera ezitali nnyingi, obubonero buno buyinza okuba akabonero akalaga nti waliwo ekintu eky’amaanyi ennyo. Embeera emu ng’eyo etatera kubaawo naye nga nkulu gy’olina okumanya eyitibwa CIDP (Chronic Inflammatory Demyelinating Polyneuropathy) . Wadde erinnya lino liyinza okulabika ng’ery’ewala katono, ka tulikuume nga lyangu.

CIDP (Obulwadde bwa Chronic Inflammatory Demyelinating Polyneuropathy) kye ki?

Wadde erinnya lino liyinza okulabika ng’ekizibu katono, singa tumenya amakulu gaalwo, tusobola okufuna endowooza ennungi ku bulwadde buno.

• Chronic: Kino kitegeeza "ekiseera ekiwanvu." Kino kitegeeza nti CIDP tejja mangu era etereera mangu. Bukula mpola, mu bbanga eritakka wansi wa wiiki munaana. Oluusi obubonero bukendeera ate ne buddamu okulabika oluvannyuma lw’emyezi oba n’emyaka. Kiringa ekizibu ekiddirira.

• Okuzimba: Kino kitegeeza "okuzimba" . Bwe tufuna obuvune awalala ku mubiri gwaffe, buzimba ne bumyufu, nedda? Ekyo kye kiri. Naye mu CIDP, okuzimba kuno kubaawo olw’ekizibu ekimu mu baserikale b’omubiri gwaffe gwennyini . Mu ngeri ennyangu, abajaasi abalina okukuuma omubiri gwaffe batandika okulumba obusimu bwaffe mu nsobi. Kino kiyitibwa ``Okulumba kw'obusimu obuziyiza endwadde'' . Okuzimba okuyitiridde okuva ku kino kwonoona obusimu bwaffe obw'okumpi . Obusimu buno obw’okumpi (peripheral nerves) bwe busimu obuva ku bwongo n’omugongo.

• Demyelinating: Kino kigambo kizitowa katono. Obusimu bwaffe obuyitibwa neurons bulina ekibikka ekibukuuma. Kiba ng’ekikuta ky’akaveera okwetooloola waya y’amasannyalaze. Ekibikka kino kiyitibwa ` (Myelin Sheath)` . Ekikuta kino ekya myelin kye kisobozesa obubaka bw’obusimu okutambula amangu era mu butuufu. `(Demyelinating)` kitegeeza nti ekikuta kya myelin kisaanawo oba kyonoonese. Olwo, nga bwe buggyiddwawo akaveera akali ku waya, akasannyalazo kakulukuta, era obubaka bw’obusimu tebutambula bulungi.

• Polyneuropathy: "Poly" kitegeeza "bangi." "Neuropathy" kitegeeza okwonooneka kw'obusimu. Polyneuropathy kitegeeza okwonooneka kw’obusimu bungi obw’okumpi mu mubiri mu kiseera kye kimu. Kino kiyinza okuvaako ebizibu eby’enjawulo gamba ng’okunafuwa kw’ebinywa, okuziyira, n’okusannyalala.

Kale, mu ngeri ennyangu, CIDP mbeera ya bbanga ddene ng’ekikuta kya myelin okwetoloola obusimu obw’okumpi kyonoonese olw’obutakola bulungi mu baserikale baffe bennyini, ekivaamu obutakola bulungi kw’obusimu bungi. Otegedde?

Njawulo ki eriwo wakati w’obulwadde bwa Guillain-Barré Syndrome (GBS) ne CIDP?

Oboolyawo ggweOyinza okuba nga wali owulidde ku ` (Guillain-Barré Syndrome)` oba ` (GBS) .` Obulwadde bwa CIDP bufaanagana nnyo ne GBS. Abasawo batwala CIDP ng’engeri ya GBS ewangaala. GBS era bulwadde obutatera kulabika nga abaserikale baffe abaserikale balumba obusimu obw’okumpi.

Naye enjawulo enkulu bwe budde. Ekisinga obubi ku GBS kitera okujja nga wayise wiiki bbiri oba ssatu ng’obubonero butandise. Naye abantu abasinga bagenda batereera mpolampola oluvannyuma lw’ekyo. Naye CIDP ewangaala nnyo. Obubonero bugenda bweyongera mpolampola mu wiiki ezitakka wansi wa munaana .

CIDP ya bulijjo etya?

CIDP mu butuufu mbeera ya bbula nnyo . Okusinziira ku banoonyereza, omuwendo gw’abantu abapya abakwatibwa obulwadde bwa CIDP mu Amerika guli wakati wa 0.8 ne 8.9 ku buli bantu 100,000 buli mwaka. Range eno nnene katono, kubanga CIDP esobola okukosa abantu ab’enjawulo mu ngeri ez’enjawulo, era kubanga obulwadde buzibu okuzuula.

CIDP esobola okukulaakulana ku myaka gyonna.

Bubonero ki obulaga CIDP?

Obubonero bwa CIDP busobola okwawukana okusinziira ku kika. Kyokka akabonero akasinga okulabika kwe kunafuwa kw’ebinywa okugenda mu maaso okumala waakiri wiiki munaana. Kino kitera okukosa enjuyi zombi ez’omubiri kyenkanyi. Okusingira ddala:

• Ebinywa by’ekitundu ky’ekisambi n’ekisambi
• Ebinywa by’ekitundu ky’ekibegabega n’omukono ogwa waggulu
• Engalo n’engalo
• Ebigere n’obugere

Teebereza, osanga osanga obuzibu okusituka okuva mu ntebe, owulira ng’otosobola kulinnya madaala, oba okukaluubirirwa okusenya enviiri zo oba okukwata ekikopo. Ebintu nga bino bisobola okubaawo.

Obubonero obulala obuyinza okulabibwa mulimu:

• Atrophy y’ebinywa ebikoseddwa
• Okuzimba, okuwunya oba okubulwa okuwulira mu ngalo n’ebigere (Paresthesia) .
• Obuzibu okukuuma bbalansi y’omubiri n’okukwatagana obubi (nga okwesittala) .
• Okukaluubirirwa okutambula oba okufiirwa ddala okutambula
• Okufiirwa oba okunafuwa kw’obusimu obuzito (deep tendon reflexes ) (kino omusawo ky’agenda okugezesa ng’akuba okugulu n’ennyondo entono) .
• Obulumi obuva ku busimu. Buno bulumi obuwulira ng’okwokya oba okukubwa amasannyalaze.

Si bulijjo nnyo, oyinza n’okulaba obubonero nga:

• Okukaluubirirwa okumira (Dysphagia) n’obunafu mu bulago obwa waggulu
• Okulaba emirundi ebiri

Obubonero buno busobola okukyuka okumala ekiseera. Bayinza okutandika mpola, oba okukulaakulana amangu. Oluusi ziyinza okujja ne zigenda, ne zikka oluvannyuma lw’ennaku ntono, ne zidda. Bw’oba ​​olina obubonero buno, kikulu okugenda ew’omusawo amangu ddala nga bwe kisoboka.Okuzuula amangu obulwadde n’okujjanjabibwa biyamba nnyo okuwona.

Waliwo ebika bya CIDP eby’enjawulo?

Yee, waliwo enjawulo ez’enjawulo eza CIDP, era obubonero bwazo bwa njawulo katono.

Ekika ekisinga okumanyibwa ye typical CIDP , ekivaako ebinywa okunafuwa n’obubonero bw’obusimu (nga okuzirika) ku njuyi zombi ez’omubiri.

Ebimu ku nkyukakyuka ezitali za bulijjo ze zino:

• ` (Multifocal Motor Neuropathy)`: Kino kizingiramu okunafuwa kw’ebinywa byokka. Obunafu buno era tebukwatagana, ekitegeeza nti busobola okukosa ekitundu kimu kyokka ku ludda olumu olw’omubiri, oba ebitundu ebiwerako mu ngeri ez’enjawulo.
• ` (Lewis-Sumner Syndrome): Kino kizingiramu obunafu bw’ebinywa obutali bwa kigero n’obubonero bw’obusimu.
• ` (Pure Sensory CIDP)`: Kino kiyinza okuvaako okuzirika, obulumi, obuzibu mu bbalansi, n’okutambula okutali kwa bulijjo. Naye tewali bunafu bwa binywa.
• `(Pure Motor CIDP):`: Mu kino, obunafu bw’ebinywa n’okufiirwa ebizimba ebikosa enjuyi zombi ez’omubiri bisobola okulabibwa, naye tewali bubonero bwa busimu.

Abanoonyereza bakyasoma enjawulo endala eza CIDP.

Kiki ekivaako CIDP?

Nga bwe twayogeddeko emabegako, abanoonyereza balowooza nti CIDP eva ku butakola bulungi mu baserikale baffe abaserikale b’omubiri . Wadde nga ekituufu ekivaako tekinnamanyika, abaserikale baffe abaserikale balaba ekikuta kya myelin ng’omulabe olwo ne batandika okukilumba (an autoimmune reaction).

Ekikuta kya myelin kye kitundu ekikuuma okwetooloola obutoffaali bwaffe obw’obusimu. Kizinga ekitundu ekiwanvu eky’obusimu (axon). Myelin kye kisobozesa amasannyalaze okutambula obulungi ku busimu. Myelin bw’eyonooneka, ebiwujjo bino eby’amasannyalaze bitambula mpola nnyo, oba bibula ddala. Olwo "obubaka" tebutuuka we buteekeddwa kugenda. Ekyo kye kireeta obubonero bwa CIDP.

Teeberezaamu waya y’amasannyalaze eyali ewunyiriza obulungi. Etambuza current bulungi. Naye kiki ekibaawo singa ekikuta ky’akaveera ku waya eyo kiva mu bifo ebimu? Current ekulukuta, oba tekulukuta bulungi, nedda? Ekyo kye kibaawo ng’ekikuta kya myelin kyonoonese.

CIDP ezuulibwa etya?

Okuzuula CIDP kiyinza okuba ekizibu kubanga ebika eby’enjawulo birina obubonero obw’enjawulo. Okuzuula CIDP, omusawo wo ajja:

• Bajja kuwuliriza bulungi obubonero bwo era bakubuuze ku byafaayo byo eby'obujjanjabi .
• Okukeberebwa kw’omubiri n’okukeberebwa kw’obusimu bikolebwa.
• Okukeberebwa okw’enjawulo okuwerako kuyinza okulagirwa okukakasa nti omuntu azuuliddwa oba okugaana embeera endala.

Bikebere ki ebikozesebwa okuzuula CIDP?

Bino bye bigezo ebiyinza okuyamba okukakasa CIDP n’okugaana ebivaako ebirala:

• Electromyography (EMG) ne Nerve Conduction Tests: Okukebera kuno kutunuulira obulamu n’enkola y’ebinywa byo n’obusimu obubifuga. Ebigezo bino bya mugaso nnyo naddala mu kunoonya enkyukakyuka mu demyelinating (okutambuza mpola obubonero bw’obusimu, okuzibikira, n’ebirala) nga CIDP. Kino kiyinza okuyamba okwawula CIDP ku bika ebirala ebya bulijjo eby’obulwadde bw’obusimu obuyitibwa polyneuropathies.

• Spinal Tap / Lumbar Puncture: Mu kukebera kuno, omusawo ayingiza empiso entono mu mugongo gwo ogwa wansi n’akwata sampuli y’amazzi go ag’omu bwongo (CSF) . Sampuli eno esindikibwa mu laabu okukeberebwa. Mu bantu 85% ku 90% abalina CIDP, omuwendo gw’obutoffaali obweru mu musaayi gwa bulijjo, naye omuwendo gwa puloteyina guli waggulu. Ebintu ebirala ebitali bya bulijjo mu CSF biyinza okulaga embeera endala.

• Magnetic Resonance Imaging (MRI) scan of the lower back: Singa emirandira gy’obusimu mu mugongo gwo ogwa wansi ginyiga langi ey’enjawulo mu kiseera ky’okukebera MRI, kiyinza okuyamba okuzuula CIDP.

• Okukebera Omusaayi: Omusawo ayinza okulagira okukeberebwa omusaayi okusobola okugaana embeera endala eziyinza okuvaako obulwadde bw’obusimu, gamba nga ssukaali, obutaba na vitamiini, obulwadde bwa thyroid, obulwadde bwa Lyme, siriimu, ne lymphoma. Era bayinza okukebera oba waliwo obutoffaali obuziyiza endwadde obuzuuliddwa nga bukwatagana ne CIDP.

• Okukebera obusimu: Tekitera kubaawo nnyo, omusawo ayinza okukuwa amagezi okukebera obusimu, nga mu kino ekitundu ky’obusimu kiggyibwamu ne kikeberebwa okulaba oba ekikuta kya myelin kyonoonese.

Bujjanjabi ki obuweebwa CIDP?

Waliwo obujjanjabi busatu obukulu (obw’olunyiriri olusooka) eri CIDP:

• Corticosteroids: Eddagala eriyitibwa steroids, nga prednisolone liyamba okukendeeza ku buzimba. Ku bantu bangi, eddagala lino erya steroids lyokka liyinza okuyamba okukendeeza ku bubonero. Kyokka, eddagala eriyitibwa steroids liyinza okuba n’ebizibu eby’amaanyi, n’olwekyo okukozesa eddagala lino okumala ebbanga eddene kitono. Omusawo ayinza n’okukuwa eddagala eddala (immunosuppressants) wamu n’eddagala eriyitibwa steroids.

• Plasma Exchange / Plasmapheresis: Mu bujjanjabi buno, ekyuma kyawula plasma ku musaayi gwo, ne kigijjanjaba, oluvannyuma ne kizza plasma n’omusaayi mu mubiri gwo. Mu ngeri ennyangu, esengejja obuwuka obw’obulabe obuli mu plasma obulumbye obusimu bwo. Okuwanyisiganya omusaayi ebiseera ebisinga kukola okumala wiiki ntono zokka. Oyinza okwetaaga obujjanjabi buno ng’okozesa n’okugiggyako okumala emyezi, oba n’emyaka.

• Intravenous Immunoglobulin Therapy (IVIG): Mu bujjanjabi buno, obutoffaali obuyitibwa immunoglobulins (obutoffaali obuziyiza endwadde bwaffe bwe bukola mu butonde okulumba abalumbaganyi) buweebwa mu misuwa (IV). Ekirungo kino ekiyitibwa immunoglobulin kifunibwa okuva mu musaayi gw’enkumi n’enkumi z’abantu abalamu. IVIG esobola okukendeeza ku kwonooneka abaserikale b’omubiri bo bwe bakola ku busimu bwo. IVIG eyinza okuweebwa mu dose nnyingi nnyo mu kusooka, era oyinza okwetaaga okufuna obujjanjabi buno buli luvannyuma lwa myezi, oba n’emyaka.

Mu kiseera kino abanoonyereza bali mu kunoonyereza ku bujjanjabi obulala ku CIDP. Oyinza n‟okufuna omukisa okwetaba mu kugezesebwa okw‟obujjanjabi ku CIDP. Yogerako n’omusawo wo ku nsonga eno.

Obulamu buli butya ne CIDP? (Okuteebereza)

Endowooza y’obulwadde buno mu bbanga eggwanvu esinziira ku bintu ebiwerako:

• Emyaka gyo CIDP lwe yatandika.
• Engeri obulwadde gye bukulaakulana n'ekika ky'obulwadde .
• Engeri obulwadde gye bwazuulibwamu amangu n'obujjanjabi ne butandika .
• Engeri omubiri gwo gye gusooka okuddamu obujjanjabi.

Abantu nga 90% abalina CIDP basobola okuwona n’obujjanjabi. Naye abantu nga 50% balina okuddamu okulwala. Okutwaliza awamu, okuteebereza okw’ekiseera ekiwanvu okw’abantu abazuuliddwa nga balina CIDP ku myaka emito kirungi. Bw’otofuna bujjanjabi bwonna ku CIDP, obusimu okwonooneka okw’olubeerera kuyinza okubaawo, ekiyinza okuvaako obulemu obumu.

Omusawo ajja kusobola okukuwa endowooza ennungi ku ky’osuubira okugenda mu maaso okusinziira ku mbeera yo entongole.

CIDP ekendeeza ku bulamu bw’abantu?

CIDP si bulwadde butta abantu. Abantu abalina obulwadde buno batera okuba n’obulamu bwe bumu n’omuntu atalina bulwadde buno. Kale tewali kintu kyonna kyeraliikirira.

CIDP esobola okuziyizibwa?

Olw’okuba abanoonyereza tebannaba kuzuula kintu kituufu ekivaako CIDP, mu kiseera kino tewali ngeri emanyiddwa ey’okuziyiza obulwadde buno okukula.

Ddi lwe nnina okulaba omusawo? / Ddi lwe nnina okugenda mu kisenge ky’abalwadde ab’amangu?

Bw’oba ​​ozuuliddwa ng’olina obulwadde bwa CIDP, olina okulaba omusawo buli kiseera okulondoola obubonero bwo n’okufuna obujjanjabi. Obubonero bwa CIDP busobola okujja ne bugenda okumala emyezi oba n’emyaka, n’olwekyo obujjanjabi obutasalako buyinza okwetaagisa.

Si bulijjo nnyo, CIDP esobola okukosa ebinywa ebyetaagisa okussa . Bw’oba ​​olina obuzibu mu kussa , kuba 911 (oba ennamba yo ey’amangu mu kitundu kyo) amangu ddala, oba genda mu kisenge ky’abalwadde ab’amangu ekikuli okumpi. Kino kya mangu.

N’ekisembayo, ebintu by’olina okujjukira

Kiyinza okukutiisa okuwulira nga tosobola kufuga mubiri gwo. Naye amawulire amalungi gali nti obubonero bwa CIDP (Chronic Inflammatory Demyelinating Polyneuropathy) busobola okujjanjabibwa naddala ng’otandika okujjanjabibwa nga bukyali. Jjukira nti ttiimu yo ey’abasawo eri naawe buli mutendera gw’ogenda okukola ku mbeera eno. Kale beera mugumu era ogoberere amagezi g'omusawo wo.

` CIDP, Obusimu, Obunafu bw’ebinywa, Okuzirika, Abaserikale b’omubiri, Myelin, Enkola y’obusimu, Obujjanjabi bwa CIDP, Chronic Inflammatory Demyelinating Polyneuropathy