Ennyinyonnyola ennyangu ku bizimba ebyewuunyisa ku magulu n’emikono: Ka tuyige ku Clear Cell Sarcoma.

Wali ofunyeeko ekizimba oba okukula okutali kwa bulijjo wansi w’olususu lw’ekigere oba omukono gwo ekitagenda kuggwaawo? Kiyinza n’obutakuluma ng’onyiga. Naye bwe kiba nga kiwulira nga kyeyongera obunene, kiyinza okuba ekintu ekyeraliikiriza. Leero tugenda kwogera ku kookolo atatera kulabika ayinza okuleeta obubonero obufaananako bwe butyo, naye kirungi okubeera nga okimanyi. Kiyitibwa Clear Cell Sarcoma .

Clear Cell Sarcoma kye ki?

Mu ngeri ennyangu, clear cell sarcoma kika kya kookolo ekitali kya bulijjo nnyo, ekisangibwa mu bitundu ebigonvu . Kigwa mu kiti ekiyitibwa sarcoma . Ebiseera ebisinga, kookolo ono atandikira mu misuwa , ebitundu ebigatta ebinywa ku magumba, n’ebitundu ebigonvu ebyetoolodde ebinywa, mu magulu go naddala mu bigere byo.

Okufaananako n’ebika bya kookolo ebirala, clear cell sarcoma nnyangu nnyo okujjanjaba singa esangibwa nga tennasaasaana mu bitundu by’omubiri ebirala. Abasawo embeera eno bagijjanjaba okusinga nga balongoosa , ate bwe kiba kyetaagisa , n'obujjanjabi obw'amasannyalaze n'oluusi n'eddagala . Ebyembi, ne bwe bamala okujjanjabwa, obulwadde buno emikisa mingi okuddamu. Eno y’ensonga lwaki abanoonyereza ku by’obujjanjabi buli kiseera banoonya engeri empya ez’okujjanjaba obulwadde bwa ‘clear cell sarcoma’.

Cler cell sarcoma ekosa etya omubiri gwange?

Clear cell sarcoma etera okutandikira mu bitundu ebigonvu ebizito okwetoloola emisuwa gyo n’ebinywa byo, oba mu layeri y’ebitundu ebiyitibwa fascia . Fascia eringa bbandi ezinga buli kizimbe mu mubiri gwaffe.

Mu kusooka, oyinza obutalaba kintu kyonna. Naye ojja kukyetegereza nga kookolo akuze n’afuuka ekizimba ekiyinza okuwulira wansi w’olususu lw’ekigere oba ekigere. Ekizimba kino kiyinza okufaanana ekizimba ekirabika ng’okubye ekigere oba ekigere kyo nnyo, naye enjawulo enkulu eri nti ekizimba kino tekikendeera okumala ekiseera . Clear cell sarcoma ekula mpola nnyo. Wabula we buba busaasaana okuva mu bitundu byo ebigonvu ebizito wansi w’olususu, kiyinza okuba nga kyatandise dda okusaasaana mu bitundu by’omubiri gwo ebirala.

Teebereza, ofuna akatundu akatono ku kigere n'okibuusa amaaso, ng'olowooza nti, "Oh, kino kiteekwa okuba nga kyakagwawo." Nga wayise wiiki oba emyezi, kikyaliwo, mpozzi n’ekineneko katono. Mu mbeera eyo, mazima ddala kirungi okunoonya amagezi g’abasawo.

Obulwadde bwa clear cell sarcoma busaasaana wa?

Clear cell sarcoma esobola okusaasaana mu bitundu by’omubiri ebirala, okusinga:

• Enkola yo ey’okugaaya emmere (enkola y’omu lubuto) .
• EbibyoEri mu mawuggwe
• Enkola yo ey’amazzi , nga eno ye nnywanto n’emisuwa gy’amazzi mu mubiri gwo.

Eno embeera ya bulijjo?

Nedda, si bwe kiri n’akatono. Kino kika kya kookolo ekitono ennyo ekitatera kulabika. Mu butuufu, sarcoma nayo kika kya kookolo ekitali kya bulijjo. Ng’ekyokulabirako, mu Amerika, abantu nga 1,600 be bazuulibwa n’obulwadde bwa sarcoma buli mwaka. Ogwo muwendo mutono, nga 1% ku kookolo yenna mu bantu abakulu. Clear cell sarcoma, ekyo kitundu 1% kyokka ku sarcomas zonna. Kale oyinza okulowooza ku ngeri kino gye tekitera kubaawo.

Ani asinga okulwala obulwadde bwa ‘clear cell sarcoma’?

Wadde nga clear cell sarcoma esobola okukula ku myaka gyonna, esinga kulabibwa mu bavubuka abali wakati w’emyaka 15 ne 40 , naddala abali mu myaka gyabwe egy’obukulu 20 ne 30.

Bubonero ki obw’obulwadde bwa clear cell sarcoma?

Nga bwe twayogeddeko emabegako, akabonero akasinga okulabika kwe kuzimba ekizimba ekitagenda wansi w’olususu ku kigere oba ekigere kyo . Ekizimba kino kiyinza okuluma oba obutalumya. Naye bwe kiba nga kiri awo era nga kiwulira nga kyeyongera obunene, ekyo kabonero kanene.

Okugatta ku ekyo, obubonero buno buyinza okulabika oluvannyuma:

• Okukoowa okuyitiridde awatali nsonga
• Okugejja mu ngeri etategeerekeka
• Entuuyo z’ekiro

Kiki ekivaako obulwadde bwa ‘clear cell sarcoma’?

Kino kizibu katono. Abanoonyereza ku by’obujjanjabi bakizudde nti obulwadde bwa ‘clear cell sarcoma’ buva ku bitundu bya chromosomes bbiri mu butoffaali bw’omubiri gwaffe okuwanyisiganya ebifo, ne bikola obuzaale obupya obugattibwa .

Mu ngeri ennyangu, kino kye kibaawo:

Obutoffaali bw’omubiri gwaffe bwe bwayawukana, oluusi chromosomes bbiri zikutuka era ebitundu ebimenyese ne biwanyisiganya. Mu mbeera eno, ebitundu bya chromosome ebikyusibwakyusibwa birimu obuzaale obuyitibwa EWSR1 ne ATF1 . Puloteeni ekolebwa obuzaale bwa EWSR1 erabika nga nkulu mu nkola y’obutoffaali. Ensengekera y’obutonde eya ATF1 eyamba okufuga okukula kw’obutoffaali. Chromosomes zino bwe zidda wamu, ebitundu by’obuzaale ebikyusiddwa bikoma mu bifo ebikyamu. Abasawo kino bakiyita reciprocal translocation . Ensonga entuufu lwaki kino kibaawo n’okutuusa kati temanyiddwa.

Bwe zimala okukyusibwa okudda mu chromosome empya, obuzaale obuwanyisiganyizibwa bukwatagana ne bukola obuzaale obugattibwa obuyitibwa EWSR1/ATF1 . Abanoonyereza balowooza nti ensengekera eno ey’obuzaale (fused gene) y’esinga okuvaako obulwadde bwa ‘clear cell sarcoma’.

Abasawo bazuula batya obulwadde bwa clear cell sarcoma?

Bw’ogenda ew’omusawo ng’alina ekizimba ng’ekyo, ajja kusooka kukukebera n’akebera ekifo ekizimba we kiri, obunene bwakyo n’ebirala. Olwo oyinza okwetaaga okukeberebwa MRI (Magnetic Resonance Imaging - MRI).Kisoboka.

Kyokka, okuzuula obulwadde bwa clear cell sarcoma kukakasibwa n’okukebera ebitundu by’omubiri (biopsy), nga kino kizingiramu okuggya akatundu akatono ak’omubiri okuva mu kizimba . Sampuli eno ey’ebitundu by’omubiri bwe yeekebejjebwa wansi wa microscope, abakugu mu by’endwadde, abakugu abeekenneenya ebitundu by’omubiri mu laabu, banoonya okubeerawo kw’ekirungo kya EWSR1/ATF1 fused gene kye twayogeddeko emabegako.

Obulwadde bwa clear cell sarcoma bujjanjabwa butya?

Ekigendererwa ekikulu eky’abasawo kwe kukomya obulwadde bwa ‘clear cell sarcoma’ obutasaasaana mu bitundu by’omubiri ebirala. Emirundi egisinga, ekisooka kwe kulongoosa okuggyawo ddala ekizimba . Singa kookolo asaasaanidde mu nnywanto, ennywanto ezo nazo ziggyibwamu. Kino kigobererwa obujjanjabi obuyambako . Kino kitera okuzingiramu obujjanjabi obw’amasannyalaze okutta obutoffaali bwa kookolo bwonna obusigaddewo.

Mu kiseera kino abanoonyereza ku by’obujjanjabi bali mu kunoonyereza ku bujjanjabi obulala. Okugeza, batunuulidde engeri obujjanjabi bw’abaserikale b’omubiri gye bukolamu mu kufuga obulwadde bwa ‘clear cell sarcoma’. Bano era bakebera oba eddagala erikozesebwa mu kiseera kino okujjanjaba ebika bya kookolo ebirala liyinza okuyamba okukomya okusaasaana kw’obulwadde bwa ‘clear cell sarcoma’.

Ekikulu kiri nti clear cell sarcoma mbeera etera okuddamu. Ekyo bwe kibaawo, kiyinza okwetaagisa okulongoosebwa ennyo n’okukozesa obujjanjabi obw’amasannyalaze. Era olw’okuba esobola okusaasaana amangu ennyo, abasawo bajja kukukebera buli kiseera balabe oba ebizimba ebipya bivaamu.

Nsobola okukendeeza ku bulabe bw’okufuna obulwadde bwa clear cell sarcoma?

Ebyembi tewali ky’oyinza kukola kukendeeza ku bulabe bw’okufuna embeera eno. Kubanga abanoonyereza ku by’obujjanjabi tebannaba kuzuula nsonga yonna ey’akabi akayinza okuvaako okulwala obulwadde bwa ‘clear cell sarcoma’. Ensonga y’akabi ye mulimu oba embeera eyongera emikisa gy’okufuna obulwadde.

Clear cell sarcoma esobola okuwona ddala?

Abasawo basobola okujjanjaba obulwadde bwa ‘clear cell sarcoma’ ekitegeeza nti basobola okuggyawo ekizimba ne bagezaako okufuga okusaasaana kwakyo. Kyokka, si mbeera ewonyezebwa ddala . Ebiseera ebisinga, clear cell sarcoma esobola okusaasaana mu bitundu by’omubiri ebirala we buzuuliddwa. Kino kyongera okukaluubiriza okujjanjaba. Era kitera okudda oluvannyuma lw’okujjanjabwa.

Omuntu alina obulwadde bwa clear cell sarcoma buwangaazi ki?

Obulamu obusuubirwa okubalirira okumala ebbanga ly’onoowangaala, okusinziira ku bulamu bwo okutwalira awamu n’ensonga z’omuntu ku bubwe. Okwekenenya okwakolebwa mu 2018 mu US National Cancer Database kwalaga nti mu bantu abalina obulwadde bwa clear cell sarcoma,Era yagamba nti 50% baali bakyali balamu nga wayise emyaka etaano bukya bazuuliddwa, ate 38% baali bakyali balamu oluvannyuma lw’emyaka kkumi nga bazuuliddwa .

Ka tube nga twogera ku bulamu oba emiwendo gy’abantu abawangaala, kikulu okujjukira nti bino kuteebereza kwokka, so si kuteebereza. Obulamu obusuubirwa okubalirira okusinziira ku muwendo gw’abantu bonna. Emiwendo gy’abawona kookolo gibalirirwa okusinziira ku bbanga abantu lye bawangaala oluvannyuma lw’okujjanjabwa ekika kya kookolo ekimu. Waliwo ebintu bingi ebiyinza okukosa obulamu bw’omuntu oba emikisa gye egy’okuwona kookolo. Bw’oba ​​olina obulwadde bwa clear cell sarcoma, omusawo asobola okukuwa amawulire agasinga obulungi ku by’osuubira.

Cler cell sarcoma esobola okutta omuntu?

Yee, kiyinza okutta omuntu. Okutwalira awamu, abantu abalina obulwadde bwa ‘clear cell sarcoma’ obusaasaanidde mu bitundu by’omubiri ebirala batera okufa amangu okusinga abo abafuna obujjanjabi nga kookolo tannasaasaana.

Ddi lwe nnina okulaba omusawo wange?

Olw’okuba obulwadde bwa clear cell sarcoma busobola okuddamu oluvannyuma lw’okujjanjabwa, omusawo ayinza okwagala okukulaba buli luvannyuma lwa myezi esatu okumala emyaka ebiri egisooka ng’amaze okujjanjabibwa, okusinziira ku mbeera gy’olimu. Kikulu okwekebejjebwa buli kiseera buli kiseera oluvannyuma lw’ekyo.

Bibuuzo ki bye nnina okubuuza omusawo wange?

Clear cell sarcoma bulwadde obutatera kulabika nnyo. Kiyinza okutta omuntu. Bw’ozuulibwa nti olina obulwadde buno, oyinza okubuuza omusawo wo ebibuuzo bino:

• Ekizimba kiri ludda wa? Kiba kinene kitya?
• Ekizimba kino kibunye awalala wonna mu mubiri gwange?
• Bujjanjabi ki bw’oteesa?
• Biki ebiva mu bujjanjabi buno?
• Bwemba nlongoosebwa, emikisa ki egy’ekizimba okudda?
• Waliwo okugezesebwa kwonna okw’obujjanjabi kwe nsobola okulowoozaako?

Mu bufunze n’obubaka bw’okutwala awaka

Clear Cell Sarcoma bulwadde busomooza ddala. Tekitera kubaawo nnyo. Bukwata abantu batono ddala omwaka. Era kikula mpola nnyo. Sarcoma esobola okusaasaana n’okutta abantu abasinga we bakiraba enkyukakyuka mu mibiri gyabwe.

Naye jjukira nti abasawo basobola okujjanjaba obulwadde bwa clear cell sarcoma. Zisobola okuggyawo ekizimba ng’olongooseddwa, era zisobola n’okukuwa obujjanjabi okutta obutoffaali bwa kookolo bwonna obusigaddewo. Ebyembi, clear cell sarcoma etera okuddamu. Kale kikulu okwekebejjebwa buli kiseera n’okumanya enkyukakyuka yonna mu mubiri gwo.

Abanoonyereza ku by’obujjanjabi banoonya engeri empya ez’okujjanjaba obulwadde bwa ‘clear cell sarcoma’. Bw’oba ​​olina clear cell sarcoma, okugezesebwa okupya mu malwaliro kubaawo.Bw’oba ​​oyagala okumanya ebisingawo ku nsonga eno, buuza omusawo wo ku nsonga eno ofune amagezi. Toggwaamu ssuubi. Bw’oba ​​akuwadde amagezi amatuufu n’obuwagizi bw’abasawo, osobola okwolekagana n’okusoomoozebwa kuno.

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