Ensigo yo eya pituitary "empty"? Ka tuyige ku bulwadde bwa Empty Sella Syndrome (ESS)!

Oluusi ofuna omutwe buli kiseera? Oba olowooza kikwatagana n’obusimu? Singa omusawo agamba nti beetaaga okukola sikaani ya ``(CT)`` ku mutwe gwo oba sikaani ya ``(MRI)``, ayinza okukizuula nti ekitundu ky'ennywanto yo ey'omu lubuto w'eri kirabika "ekyerere." Ekyo kye tuyita Empty Sell. Naye bulijjo kiba kizibu kinene? Kino ka twogere mu bujjuvu.

Obulwadde bwa Empty Sella Syndrome (ESS) kye ki?

Mu ngeri ennyangu, obulwadde bwa Empty Sella Syndrome (ESS) embeera etali ya bulijjo nnyo. Kibaawo ng’endwadde yo eya pituitary gland – enseke entono naye nga nkulu nnyo esangibwa ku musingi gw’obwongo bwo – efuuse empanvu oba okukendeera mu kifo kyayo, ekituli ky’amagumba ekiyitibwa sella turcica . Lowooza bw’ati, sella turcica eringa akayumba akatono akakuuma enseke z’omubiri (pituitary gland). Olw’ensonga ezimu, ‘ennyumba’ eno eyinza okufuuka ennene ennyo, ekivaako endwadde z’omubiri (pituitary gland) okubumbulukuka n’efuuka entono.

Ekigambo ‘sella turcica’ kiva mu Lulatini, ekitegeeza ‘entebe y’Olutuluuki’. Lituumiddwa bwe lityo kubanga lifaanana enkula y’amatandiiko g’embalaasi. Abantu abamu abalina ESS basobola okufuna obubonero nga obutakwatagana mu busimu , okulumwa omutwe emirundi mingi , n'okukyuka mu kulaba .

Obadde okimanyi nti enseke y’omubiri (pituitary gland) kitundu kikulu nnyo mu nkola yaffe ey’omubiri (endocrine system ) , nga eno y’enkola ekola obusimu. Kikola obusimu bungi obukulu mu mubiri gwaffe. Obusimu buno bufuga endwadde endala mu mubiri gwaffe.

Njawulo ki eriwo wakati wa Empty Sella ne Empty Sella Syndrome?

Kino kitabula katono, n’olwekyo wuliriza bulungi. Wadde ebigambo ‘empty cell’ ne ‘empty cell syndrome’ oluusi bikozesebwa nga bikyusibwakyusibwa, waliwo enjawulo entono. Mu bufunze, akatoffaali akataliiko kintu kyonna kizuuliddwa mu ngeri ya radiological , ate empty cell syndrome mbeera ya bujjanjabi.

‘Empty Sella’ y’ennywanto yo ey’omubiri (pituitary gland) bw’erabika ng’efuukuuse oba ng’ekendedde ku sikaani. Mu mbeera eno, abasawo tebasobola kulaba bulungi nseke ya pituitary ku sikaani. N’olwekyo, ekifo w’eri enseke z’omubiri ekiyitibwa pituitary gland, ekiyitibwa sella turcica, kirabika ‘ekyerere’. Wano erinnya 'empty sella' we liva.

Wabula mu butuufu sella turcica si bwereere. Ebiseera ebisinga, kijjula amazzi g’omu bwongo (CSF) . CSF eno ge mazzi ageetoolodde n’okukuuma obwongo bwaffe n’omugongo. Mu mbeera ya ‘empty sella’, amazzi gano aga CSF gakulukuta mu sella turcica ne gateeka puleesa ku nseke y’omubiri (pituitary gland). Puleesa eyo ereetera endwadde eno okukendeera oba okufuumuuka.

Ebiseera ebisinga, abasawo bazuula ‘akasenge kano akataliimu kintu’ mu butanwa. Kwe kugamba, bwe bakola ``(CT)`` scan oba ``(MRI)`` scan y'omutwe olw'ensonga endala.

Newankubadde abantu abamu balina ‘obutoffaali bwereere’ ku sikaani zaabwe, tebasobola kuba na bubonero bwonna era n’endwadde zaabwe ez’omu lubuto (pituitary gland) zisobola okukola obulungi.

Wabula singa omuntu aba ne ‘empty sella’ ate nga n’endwadde ye ey’omu lubuto (pituitary gland) tekola bulungi, ekyo kye tuyita Empty Sella Syndrome (ESS) . Obulwadde bwa syndrome kwe kukuŋŋaanyizibwa kw’obubonero obukwatagana. Abantu abalina ESS basobola okufuna ebintu nga obutakwatagana mu busimu, enkyukakyuka mu kulaba, n’okulumwa omutwe emirundi mingi.

Empty Sella erina ebika bibiri, nedda?

Yee, sikaani yo bw’ezuula ‘obutoffaali njereere’, abasawo bagigabanya mu bika bibiri: ebisookerwako n’ebyokubiri.

• Primary Empty Sella (PES): Wano abasawo we batasobola kuzuula kizibu kitegeerekeka bulungi ekivaako endwadde yo ey’omu lubuto okufuuka ekipapajjo. Ebiseera ebisinga, primary empty sella tereeta empty sella syndrome. Kino kitegeeza nti tekitera kuleeta bubonero.
• Secondary Empty Sell (SES): Kino kiva ku mbeera endala emanyiddwa ekosa ensengekera y’endwadde yo ey’omu lubuto oba sella turcica. Mu ngeri ennyangu, kiva ku kwonooneka okuva mu bulwadde oba ekintu ekirala ekibaawo. Mu mbeera za secondary empty sella (SES), obulwadde bwa empty sella syndrome butera okubeerawo okusinga mu mbeera za primary empty sella (PES).

Obulwadde buno obwa Empty Sella Syndrome (ESS) butiisa obulamu?

Nedda, obulwadde bwa Empty Sella Syndrome (ESS) si mbeera eyinza okutta omuntu. Kisobola okujjanjabibwa n’eddagala ly’obusimu n’oluusi n’alongoosebwa.

Ate era olw’okuba sikaani y’obwongo bwo egamba nti ‘empty cell’ tekitegeeza nti eri mu matigga. Mu mbeera ezisinga eza ‘empty cell’, tewali bubonero oba empty cell syndrome.

Omulimu gwa Pituitary Gland guli gutya?

Ensigo y’omubiri (pituitary gland) nsonga nkulu nnyo ey’omubiri (endocrine gland) mu mubiri gwaffe. Kikola obusimu bungi obw’enjawulo. Era egamba endwadde endala mu nkola yaffe ey’omubiri (endocrine system) okufulumya obusimu. Ekyo kili:

• Endwadde z’ekibumba
• Enkwaso (mu bakyala) oba ensigo (mu basajja) .
• Ensigo ya thyroid

Obusimu bulinga ababaka b’eddagala. Zitambula mu musaayi ne zitwala obubaka mu bitundu byaffe, ebinywa n’ebitundu ebirala. Obubaka buno butegeeza omubiri eky’okukola ne ddi lwe gulina okukikola.

Ensigo ya pituitary eyungibwa ku hypothalamus mu bwongo bwaffe.Kiyungibwa ekikolo ekikoleddwa mu misuwa n’obusimu. Kino kiyitibwa ekikolo ky’omubiri ekiyitibwa pituitary stalk. Mu kikolo kino, hypothalamus w’eyogera n’endwadde ya pituitary gland n’egamba nti, ‘Okay, kati fulumya obusimu buno.’ Hypothalamus kye kitundu ky’obwongo bwaffe ekifuga ebintu nga puleesa, okukuba kw’omutima, ebbugumu ly’omubiri, n’okugaaya emmere.

Ensigo ya pituitary okusinga ekola obusimu buno wammanga:

• Adrenocorticotropic hormone (ACTH): Kino kisitula endwadde z’ekibumba okukola obusimu (e.g. cortisol) obuddamu situleesi.
• Antidiuretic hormone (ADH oba vasopressin): Efuga bbalansi y’amazzi mu mubiri.
• Follicle-stimulating hormone (FSH): Ayamba okukula amagi mu bakyala n’okufulumya ensigo mu basajja.
• Growth hormone (GH): Eyamba emibiri gyaffe okukula okuva mu buto okutuuka mu bukulu naddala mu magumba n’ebinywa.
• Luteinizing hormone (LH): Ekolagana ne FSH okuyamba enkola y’okuzaala okukola. Kikulu nnyo mu kuggyamu eggi mu bakyala n’okukola eddagala eriyitibwa testosterone mu basajja.
• Oxytocin: Ayamba nnabaana okukonziba ng’ozaala ate amata okuleka wansi ng’oyonsa.
• Prolactin: Ayamba okukola amata g’amabeere.
• Obusimu obusitula thyroid (TSH): Bugamba endwadde y’ekibumba mu bulago okukola obusimu bwa thyroid. Obusimu buno obwa thyroid bufuga omutindo omubiri gwaffe gwe gukozesa amaanyi (metabolism).

Obusimu buno bwonna tebukolebwa buli kiseera. Ebisinga bifulumizibwa mu kubwatuka, nga buli ssaawa emu oba ssatu.

Ani asinga okukosebwa obulwadde bwa Empty Sella Syndrome (ESS)?

Wadde nga eno embeera etali ya bulijjo, abaana n’abantu abakulu basobola okulwala obulwadde bwa empty sella syndrome (ESS).

Wabula, primary empty cell (PES) – ekitegeeza nti eyo erabika ku sikaani yokka nga tewali bubonero bwonna – esinga emirundi nga ena mu bakyala okusinga mu basajja.

PES esinga kubeera mu bantu abali wakati w’emyaka 30 ne 40. Oluusi esobola okubaawo amangu mu bakyala okusinga mu basajja. Abakyala abafunye olubuto olujjuvu naddala bali mu bulabe bw’okufuna PES.

PES tetera kubeera mu baana okusinga mu bantu abakulu. Bwe kibaawo, kitera okukwatagana n’embeera endala ez’obujjanjabi, gamba ng’obulwadde bwa Turner, obulwadde bwa Moyamoya, n’obulwadde bwa Prader–Willi.

Kino kya bulijjo kitya?

Obulwadde bwa Empty Sella Syndrome (ESS) butono nnyo. Abanoonyereza abamu bateebereza nti abantu abatakka wansi wa 1% abalina ‘empty sella’ bafuna obubonero (i.e., bafuna ESS).

Wabula okubeera ne sella njereere nga tolina bubonero kisingako nnyo. Lipoota ezimu ziraga nti wakati w’ebitundu 8% ne 35% ku bantu bayinza okuba ne sella njereere. Lipoota endala ziraga nti abantu nga 12% balina sella njereere, okusinziira ku bivudde mu kukebera obwongo.

Bubonero ki obulaga obulwadde bwa Empty Sella Syndrome (ESS)?

Akabonero akakulu akakwatagana n’obulwadde bwa empty sella syndrome (ESS) kwe kulumwa omutwe obutawona. Wabula abanoonyereza n’okutuusa kati tebakakasa oba okulumwa omutwe kuno kuva ku ESS oba kwa butanwa. Kino kiri bwe kityo kubanga abantu bangi abalina ESSA nabo balina puleesa (hypertension), era eyinza okuvaako okulumwa omutwe singa efuuka ya maanyi.

ESS etera okuleeta obutakwatagana mu busimu olw’okwonooneka kw’endwadde z’omubiri (pituitary gland). Abantu abalina ESS bayinza okufuna obubonero obw’enjawulo okusinziira ku kwonooneka kw’endwadde zaabwe ez’omu lubuto (pituitary gland) n’obusimu ki obukoseddwa. Bw’oba ​​olina ESS, oyinza okuba n’obubonero buno wammanga:

• Amazzi agatali ga mata okuva mu mabeere (galactorrhea) (kino nakyo kisobola okutuuka ku basajja) .
• Obuzibu bw'okusituka ( eri abasajja) .
• Okugenda mu nsonga ezitali za bulijjo oba obutagenda mu nsonga yonna (amenorrhea) (eri abakyala) .
• Okukendeera oba okubulwa obwagazi (low libido) .
• Okuwulira nga okooye buli kiseera (Obukoowu) .

Si bulijjo nnyo, abantu abamu abalina ESS nabo bayinza okufuna obubonero nga:

• Puleesa okweyongera munda mu kiwanga (benign intracranial pressure) .
• Cerebrospinal rhinorrhea (okukulukuta kwa CSF okuva mu nnyindo) .
• Okuzimba kw’ekisenge ky’amaaso munda mu liiso (papilledema) olw’okunyigirizibwa okweyongera mu kiwanga
• Okulaba kukyuka, okugeza, okulaba okutali kwa maanyi.

Nate, osobola okuba n’akatoffaali akataliimu ‘akatoffaali’ ku sikaani y’obwongo, naye oyinza obutaba na bubonero bwonna. Mu butuufu abantu bangi abalina ‘obutoffaali obwereere’ tebalina bubonero bwonna era tebajja kuba na bubonero bwonna.

Obulwadde bwa Empty Sella Syndrome (ESS) buleeta okugejja?

Singa endwadde yo eya pituitary tekola busimu bumala thyroid-stimulating hormone (TSH) olw’obulwadde bwa empty sella syndrome (ESS), waliwo omukisa nti ojja kweyongera okugejja.

TSH esitula endwadde ya thyroid, esangibwa mu maaso g’ensingo yo, wansi w’olususu, okufulumya obusimu bwa thyroid. Omulimu omukulu ogw’endwadde ya thyroid kwe kukola obusimu bwa thyroid, obufuga sipiidi gy’okyusa emmere gy’olya n’efuuka amaanyi, oba omutindo gw’okukyusakyusa emmere yo .

Singa endwadde yo eya pituitary eba tekola TSH emala olw’obulwadde bwa ESS, endwadde yo eya thyroid eyinza obutakola busimu bwa thyroid bumala. Kino kiyinza okuvaako omubiri gwo okukendeera olw’obusimu bwa thyroid obutono ekiyinza okukuleetera okugejja.

Kiki ekivaako obulwadde bwa Empty Sella Syndrome (ESS)?

Obulwadde bwa Empty Sella Syndrome (ESS) buyinza okuva ku primary empty sella (PES) oba secondary empty sella (SES). Wabula, secondary empty sella (SES) esinga okuleeta ESS.

Ebivaako obulwadde bwa Primary Empty Sella Syndrome (PES) .

Obulwadde bw’omumwa gwa nnabaana obusookerwako (PES) bubaawo ng’ekimu ku bitundu ebibikka ebweru w’obwongo bwo (oluwuzi lwa arachnoid), sella turcica, kibuguma munda, ne kinyigiriza ku nnywanto y’omubiri (pituitary gland).

Abasawo n’okutuusa kati tebannasobola kuzuula kituufu ekivaako obulwadde bwa primary empty sella syndrome.

Endowooza emu eri nti obunafu obuzaalibwa mu bitundu ebibikka obwongo busobozesa amazzi g’omu bwongo (CSF) okuyingira mu sella turcica, ne gafuula enseke y’omubiri (pituitary gland) empanvu. Mu mbeera ng’ezo, enseke y’omubiri (pituitary gland) etera okuba enzibu okulaba ku sikaani, naye etera okukola obulungi, n’olwekyo obulwadde bwa empty sella syndrome tebubaawo.

Ebivaako obuzibu bw’okusituka mu ngeri ey’okubiri (SES) .

Secondary empty sella (SES) ebaawo nga pituitary gland yo oba sella turcica eyonoonese obulwadde oba ekintu ekirala ekibaawo. N’olwekyo, waliwo ebintu bingi ebiyinza okuvaako SES. Okutwaliza awamu, ebikulu ebivaako okwonooneka kuno bye bino:

• Ekizimba ku bwongo .
• Obujjanjabi bw'amasannyalaze .
• Okulongoosa obwongo okwakolebwa mu kitundu ekyetoolodde enseke y’omubiri (pituitary gland).
• Obuvune obw’amaanyi ku mutwe, okugeza obuvune ku bwongo obw’ekikangabwa.

Wano waliwo ebintu ebirala ebitongole ebiyinza okukosa okufuluma kw’ekibumba okw’okubiri:

• Ebizimba ku bwongo: Oluusi ebizimba ku bwongo bisobola okuleeta puleesa okwetooloola obwongo bwo (intracranial pressure), ekiyinza okunyigiriza ku nseke y’omubiri (pituitary gland).
• Idiopathic intracranial hypertension (IIH): IIH kwe kweyongera kwa puleesa munda mu kiwanga olw’okuzimba amazzi g’omu bwongo (CSF) okwetooloola obwongo bwo. Puleesa eno esukkiridde esobola okunyigiriza endwadde y’omubiri (pituitary gland).
• Pituitary adenomas: Bino bizimba ebikula mu nseke. Ebiseera ebisinga, tezirina kookolo (benign). Adenomas zino zisobola okussa puleesa ku pituitary gland ne zigyonoona.
• Obulwadde bwa Sheehan: Eno mbeera oluusi eyinza okubaawo singa wabaawo omusaayi oguyitiridde, oguyinza okutta omuntu ng’ozaala. Kino kiyinza okuvaako omubiri obutaba na mukka gwa oxygen n’okwonoona enseke y’omubiri (pituitary gland).

Obulwadde bwa Empty Sella Syndrome (ESS) buzuulibwa butya?

Ebiseera ebisinga abasawo basanga sella njereere mu butanwa, bwe bakola sikaani y’omutwe olw’ensonga endala. Ate era abantu bangi abalina sella empty tebafuna bulwadde bwa empty sella oba tebafuna bubonero bwonna.

Kyokka bw’oba ​​olina obubonero obukwata ku bulwadde bw’obutoffaali obutaliimu kintu kyonna, gamba ng’okulumwa omutwe emirundi mingi n’obusimu obutakwatagana, omusawo wo ajja kukubuuza ku byafaayo by’obujjanjabi bwo, akukebere omubiri, era kirabika alagire okukeberebwa omutwe n’obwongo.

Sikaani ezikozesebwa okuzuula obulwadde bwa ESS ze zino:

• CT y’obwongo (computed tomography): CT scan y’engeri y’okukuba ebifaananyi ebitegeerekeka obulungi eby’obwongo bwo n’endwadde z’omubiri (pituitary gland) ng’okozesa X-ray ne kompyuta.
• Sikaani y’obwongo mu ngeri ya magnetic resonance imaging (MRI): Sikaani ya MRI ekozesa amayengo ga leediyo ne magineeti ez’amaanyi okukola ebifaananyi ebitegeerekeka obulungi ennyo eby’ebitundu ebiri munda mu mubiri gwo, gamba nga sella turcica yo.

Omusawo ayinza n’okulagira okukeberebwa ebirala, gamba ng’okukeberebwa omusaayi, okukebera obusimu bwo.

Oluusi, abasawo bayinza n’okukola ebigezo nga bino okukebera oba puleesa yeeyongedde mu bwongo bwo:

• Laga omusawo w’amaaso akukebere retina munda mu liiso lyo.
• Lumbar puncture (spinal tap) – Kino kipima puleesa y’amazzi g’omugongo.

Bujjanjabi ki obw’obulwadde bwa Empty Sella Syndrome (ESS)?

Sikaani zo ne bwe ziraga nti ‘obutoffaali bwereere’, singa endwadde yo ey’omu lubuto (pituitary gland) ekola bulungi, tojja kwetaaga bujjanjabi bwonna. Kino kye kibeerawo ebiseera ebisinga.

Wabula bw’oba ​​olina obulwadde bwa Empty Sella Syndrome (ESS) ate ng’endwadde yo ey’omu lubuto tekola bulungi, obujjanjabi buba ddagala eritereeza obusimu obutono. Kwe kugamba, eddagala lisalibwawo okusinziira ku busimu ki obutono.

Singa ESS ereetera amazzi g’omu bwongo (CSF) okukulukuta okuva mu nnyindo yo (CSF rhinorrhea), oyinza okwetaaga okulongoosebwa okuddaabiriza sella turcica yo.

Biki ebiyinza okuleeta obulwadde bwa Empty Sella Syndrome (ESS)?

Abasawo tebakakasa ddala kiki ekivaako obulwadde bwa empty sella syndrome mu bantu abamu abalina empty sella. Wabula obulwadde bwa empty sella syndrome butera okuva ku secondary empty sella (SES) okusinga primary empty sella (PES). Kino kitegeeza nti singa sella njereere eva ku kintu ekirala, gamba ng’ekizimba ku bwongo, obujjanjabi bw’amasannyalaze oba obuvune ku mutwe, otera okufuna obubonero.

Kiki ekitegeeza omuntu alina obulwadde bwa Empty Sella Syndrome (ESS)?

Okutwalira awamu endowooza y’omuntu alina obulwadde bwa empty sella syndrome (ESS) nnungi. Waliwo eddagala erijjanjaba obutakwatagana mu busimu. Bw’oba ​​olina obutakwatagana mu busimu olw’obulwadde bwa ESS, oyinza okwetaaga okumira eddagala obulamu bwo bwonna.

Ddi lw’osaanidde okulaba omusawo bw’oba ​​olina obulwadde bwa empty cell syndrome?

Bw’oba ​​ozuuliddwa n’obulwadde bwa Empty Sella Syndrome (ESS), n’ofuna obubonero obupya oba singa obubonero bwo obuliwo bweyongera, laba omusawo mu bwangu.

Bw’oba ​​omira eddagala ly’obusimu obutakwatagana olw’obulwadde bw’olubuto olutaliimu, kikulu nnyo okulaba omusawo buli kiseera okukakasa nti eddagala lyo likola bulungi.

Kale, kiki kye tusaanidde okujjukira mu kino?

Well, Empty Sella Syndrome (ESS) mu butuufu mbeera etali ya bulijjo nnyo. Wabula kya bulijjo nnyo okukizuula nti olina ekintu ekiyitibwa ‘empty cell’ ku bwongo. N’olwekyo totya olw’okuba omusawo bw’agamba. Ebiseera ebisinga, abantu abalina ‘empty cell’ tebalina bubonero bwonna era tebafuna bulwadde bwa Empty Sella Syndrome.

Bw’oba ​​olina ekibuuzo kyonna ku lipoota yo eya sikaani, totya kubuuza musawo wo. Baliwo okukuyamba. Okufaayo ku bulamu bwo kye kintu ekisinga obukulu.

` Empty Sella Syndrome, Enseke z’omu lubuto, Obusimu, Okukebera obwongo, Sellae Tursica