Ofuna obuzibu n’obungi bwa calcium obutono oluvannyuma lw’okulongoosebwa? Kiyinza okuba nga 'Hungry Bone Syndrome'!

Nga bw’oyinza okuba ng’okimanyi, oluvannyuma lw’okulongoosebwa okumu naddala ezo eziggyawo endwadde z’ekibumba mu bulago oba endwadde za parathyroid eziriraanyewo, omubiri guyinza okufuna obuzibu obw’enjawulo obutonotono. Abantu abamu bayinza okuwulira nga bakooye mu ngeri etayinza kulowoozebwako, okulumwa omubiri oba okuwulira nga basobeddwako katono. Kale bw’oba ​​ggwe oba omuntu gw’omanyi alina ekintu nga kino, kiyinza okuba nga kiva ku mbeera gye tugenda okwogerako leero eyitibwa ‘Hungry Bone Syndrome’. Erinnya liwulikika nga lya kyewuunyo katono, si bwe kiri? Oyinza okuba ng'olowooza nti, "Kitegeeza ki okubeera n'amagumba agalumwa enjala?" Ka tulabe kiki kye kiri, mu bigambo ebyangu.

‘Obulwadde bw’amagumba g’enjala’ kye ki?

Mu ngeri ennyangu, Hungry Bone Syndrome mbeera ng’omuwendo gwa calcium mu musaayi gwo gukendeera mu bwangu. Kino abasawo bakiyita ``Hypocalcemia''. Embeera eno etera okulabibwa oluvannyuma lw’okulongoosebwa endwadde za parathyroid. Obadde okimanyi nti endwadde za parathyroid nkulu nnyo mu kufuga calcium mu mubiri gwaffe?

Abantu abalina obulwadde buno obwa ‘hungry bone syndrome’ bayinza obutakoma ku kuba na calcium mutono, naye oluusi n’obungi bwa magnesium (`(Hypomagnesemia)`) ne phosphorus (`(Hypophosphatemia)`) mu musaayi gwabwe. Bino nabyo by’obuggagga bw’omu ttaka ebikulu emibiri gyaffe bye gwetaaga.

Naye tewali kye yeeraliikirira. ‘Hungry Bone Syndrome’ mbeera esobola okujjanjabibwa n’okuwona . Ekisinga obukulu kwe kukitegeera mu budde n’otandika okujjanjaba.

Embeera eno ya bulijjo etya?

Abanoonyereza mu butuufu tebalina kirowoozo kituufu ku ngeri ‘obulwadde bw’amagumba g’enjala’ gye butera okubaawo, kuba buyinza okwawukana okusinziira ku muntu.

Wabula okunoonyereza okumu kulaga nti abantu wakati wa 4 ne 13 ku 100 ababadde balongoosebwa parathyroidectomy olw’embeera eyitibwa primary hyperparathyroidism bafuna embeera eno. Ate era, lipoota ezimu zigamba nti oluvannyuma lw’okulongoosebwa olw’obulwadde bwa secondary ne tertiary hyperparathyroidism, emikisa gy’embeera eno okukula giyinza okuba waggulu nga 20 ku 70 ku 100. Kale, kirabika nti kino kiyinza okuba nga kya bulijjo katono mu mbeera ezimu.

Bubonero ki obulaga obulwadde bwa ‘Hungry Bone Syndrome’?

Obubonero bwa ‘Hungry Bone Syndrome’ bufaanagana nnyo n’obwo obuva ku kalisiyamu omutono mu musaayi (Hypocalcemia). Bino biyinza okuba ebitonotono ng’akazimba akatono mu bantu abamu, okutuuka ku maanyi ng’okutabulwa oba okukonziba mu balala. Bino bye bimu ku bubonero obulaga nti obulwadde buno:

• Okuyiringisiza oba okusika ennyama: Okuwulira ng’ennyama eri mu magulu oba mu mikono eyiringisibwa yokka.
• Obunafu bw’ebinywa: Owulira nga tolina bulamu era ng’okooye nnyo nga tosobola kukola kintu kyonna.
• Obulumi bw’amagumba: Okuwulira ng’amagumba agali mu mubiri galumwa.
• Obukoowu obw’amaanyi: Obukoowu obutaggwaawo ne bwe weebase.
• Okutabulwa: Okukaluubirirwa okussaayo omwoyo, obutamanya kya kukola.
• Obuzibu mu kujjukira: Okwerabira ebintu.
• Okunyiiga oba okunyiiga: Okunyiiga olw’ebintu ebitonotono, okuwulira nga tolina mirembe.
• Okwennyamira: Okuwulira ennaku n’obutaba na ssuubi.
• Okuzirika mu mimwa, olulimi, engalo, ne/oba ebigere: Ebitundu bino biwulira nga biwunya, oba ng’enseenene ezidduka.
• Okukaluubirirwa okussa olw’okusannyalala kw’ebinywa by’emimiro (`(Laryngospasm)`): Kino kya bulabe katono, kizibuwalira okussa.
• Okukaluba kw’ebinywa n’okunyiganyiga (`(Tetany)`): Embeera ebinywa by’omubiri mwe bikaluba ne binyiganyiga.
• Okukonziba: Buno nakyo kabonero ka maanyi.

Ng’oggyeeko obubonero buno, nga bwe kyayogeddwako emabegako, magnesium ne phosphorus omutono mu musaayi (`(Hypomagnesemia)` ne `(Hypophosphatemia)`) nazo ziyinza okubaawo. Obubonero bw’embeera zino bufaanagana nnyo n’obw’ekirungo kya calcium ekitono. Era zisobola okuleeta obuzibu mu binywa, okukonziba, n’okukuba kw’omutima okutali kwa bulijjo (`(Arrhythmia)`).

Obulwadde bw'amagumba g'enjala butera okubaawo mu ssaawa 18 oluvannyuma lw'okulongoosebwa parathyroid oba thyroid .

Lwaki ‘Hungry Bone Syndrome’ eno ebaawo?

Waliwo ebikulu ebiwerako ebivaako ‘Hungry Bone Syndrome’:

• Oluvannyuma lw’okulongoosebwa parathyroid (`(Parathyroidectomy)`) ku bulwadde bwa hyperparathyroidism obusookerwako oba obw’okubiri.
• Obulwadde bwa thyrotoxicosis mbeera ebaawo oluvannyuma lw’okuggyibwako thyroid yonna.
• Kookolo w’enseke bw’asaasaana mu magumba (metastasized).

Okutegeera obulungi lwaki kino kibaawo, kikulu okutegeera katono ku ngeri emiwendo gya calcium gye gitereezebwa mu mibiri gyaffe.

Teebereza, emabega w’endwadde yo eya thyroid mu bulago bwo, waliwo obusimu buna obutono obuyitibwa parathyroid glands. Endwadde zino zikola obusimu obuyitibwa parathyroid hormone (PTH) . Omulimu omukulu ogw’obusimu buno obwa PTH kwe kufuga omuwendo gwa calcium mu musaayi (si mu magumba, wabula mu musaayi). PTH era eyamba okufuga emiwendo gya phosphorus (nayo mineral) ne vitamin D (nayo hormone) mu musaayi n’amagumba.

Kale, omubiri gwo bwe guwulira nti calcium mu musaayi gwo mutono, endwadde za parathyroid zifulumya obusimu bwa PTH. PTH eno egenda n’efulumya ekirungo kya calcium ekitono okuva mu magumba n’akigatta mu musaayi. Olwo calcium mu musaayi n’edda mu mbeera eya bulijjo.

Kati, teebereza nti omuntu alina endwadde z’omubiri eziyitibwa parathyroid glands ezisukkiridde, era balongoosebwa okuziggyamu. Ekibaawo nti obusimu bwa PTH obwali bungi ennyo edda bukendeera mangu. Oluusi, bwe balongoosebwa thyroid, singa endwadde za parathyroid eziriraanyewo zoonoonebwa mu butanwa, emiwendo gya PTH nagyo giyinza okukka.

Emiwendo gya PTH bwe gikka mu bwangu, omuwendo gwa calcium mu magumba amakadde addamu okuyingizibwa mu musaayi (`(Resorption)`) gukendeera, era omuwendo gw’amagumba amapya agatondebwa (`(Bone Formation)`) gweyongera. Kino kireetera amagumba "okufa enjala" ya calcium. Eno y’ensonga lwaki kino kiyitibwa ‘hungry bone syndrome’.

Kino kye kibaawo nga kookolo w’enseke asaasaana mu magumba. Eyo, emirimu gy’obutoffaali obuzimba amagumba (`(Osteoblastic activity)`) gyeyongera, kale amagumba geetaaga calcium omungi.

Ani ali mu bulabe obw’amaanyi obw’okulwala ‘Hungry Bone Syndrome’?

Abantu abamu batera okufuna embeera eno. Ka tulabe kye bali:

• Obusimu obuyitibwa parathyroid hormone (PTH) bungi nnyo mu musaayi.
• Okwongera ku muwendo gwa alkaline phosphatase mu musaayi.
• Calcium mu musaayi atera kuba mutono.
• Okubeera n’obutaba na vitamiini D.
• Okukola okulongoosa thyroid ne parathyroid mu kiseera kye kimu.
• Okwongera ku muwendo gwa urea nitrogen (BUN) mu musaayi.
• Omugejjo, kwe kugamba, okugejja ennyo.
• Okulongoosa okuggyawo endwadde ya parathyroid ennene okusinga eya bulijjo.
• Okusaasaana kw’obutoffaali bwa kookolo okutuuka mu magumba (Metastatic tumors of the bones).
• Okubeerawo kw’endwadde ezikwatagana n’amagumba nga ebizimba ebya kitaka ne osteitis fibrosa cystica.

Abantu abalina ensonga zino ez’akabi batera okulwala ‘hungry bone syndrome’.

Kino abasawo bakizuula batya?

Omusawo atera okusooka okuzuula oba olina ‘hungry bone syndrome’ ng’akola okukebera omusaayi gwa ‘calcium’. Okutwalira awamu, singa omuwendo gwa calcium mu musaayi gwo guba wansi wa 8.4 mg/dL okumala ennaku ezisukka mu nnya, kitwalibwa ng’ekintu eky’obulabe eri ‘hungry bone syndrome’.

Tekikoma awo, naye omusawo wo ayinza n’okukola ebigezo ebirala ebitonotono okulaba oba embeera eno ekosezza ebintu ebirala ebikwata ku bulamu bwo:

• Okukebera omusaayi okulala: Omusaayi gwo guyinza okukeberebwa oba gulina magnesium, phosphorus, parathyroid hormone (PTH), ne/oba vitamin D.
• EKG (Electrocardiogram): Okukebera kuno kupima ennyimba z’omutima gwo nga kusiba obuuma obuyitibwa electrodes ku kifuba kyo. Kino kikulu kubanga ekirungo kya calcium ekitono mu musaayi (hypocalcemia) ne ‘hungry bone syndrome’ bisobola okuvaako omutima okukuba obutasalako.
• Okukebera ebifaananyi by’amagumba: Okukebera kuno kuyinza okukebera oba waliwo obuzibu ku magumba go, gamba ng’okumenya, okulema oba ebizimba.

Bujjanjabi ki obw’obulwadde bwa ‘Hungry Bone Syndrome’?

Tofaayo, waliwo obujjanjabi obulungi ku kino. Ekigendererwa ekikulu eky’obujjanjabi kwe kuzza omuwendo gwa kalisiyamu mu musaayi gwo ku mutindo omulamu. Emirundi egisinga, ojja kufuna obujjanjabi buno ng’oli mu ddwaaliro. Obujjanjabi buyinza okuli:

• Okuwa calcium ng’oyita mu musuwa (`(IV Calcium - Calcium Gluconate)`): Kino kiyamba okuzzaawo amangu calcium.
• Ebirungo bya Calcium ebiweebwa mu kamwa (Calcium Citrate oba Calcium Carbonate): Bino biweebwa okukuuma omuwendo gwa calcium.
• Vitamin D Supplements mu kamwa: Vitamin D yeetaagibwa nnyo omubiri okusobola okunyiga calcium.
• Okukyusa magnesium: Singa magnesium eba ntono, ekyo nakyo kyetaaga okutereezebwa.

Abasawo bajja kwekenneenya embeera yo era bazuule obujjanjabi obusinga okukusaanira.

Kinatwala bbanga ki okuwona embeera eno? Ebiseera eby’omu maaso bye biruwa?

Amawulire amalungi gali nti embeera eno, ‘Hungry Bone Syndrome’, kumpi ewona ddala . Ekyo kitegeeza nti prognosis nnungi nnyo.

Kyokka ne bwe kiba nga kijjanjabiddwa, obudde embeera eno bw’etwala okuggwaawo mu bujjuvu buyinza okwawukana. Abantu abamu batereera mu nnaku ntono ate abalala bayinza okutwala emyezi egiwerako. Mu mbeera ezitali nnyingi nnyo, esobola okumala omwaka mulamba.

Ekisinga obukulu, singa tebujjanjabwa, hypocalcemia ey’amaanyi eyinza okuvaako ebizibu ebiyinza okutta omuntu ng’okukonziba. N’olwekyo, kikulu okunoonya obujjanjabi mu bwangu singa obubonero bubaawo.

'Hungry Bone Syndrome' esobola okuziyizibwa?

Okuva ‘hungry bone syndrome’ bwe kiyinza okubaawo oluvannyuma lw’okulongoosebwa parathyroid (`(Parathyroidectomy)`) oba okulongoosebwa thyroid (`(Thyroidectomy)`), abasawo bagezaako okukola emitendera okubuziyiza ne bwe baba nga tebannalongoosebwa. Ka tulabe kye bali:

• Okukebera nga tonnalongoosebwa: Nga tonnalongoosebwa , omusawo wo ajja kukebera obungi bw’amagumba go, calcium mu musaayi, phosphate, PTH, ne vitamin D. Ebigezo bino bisobola okuyamba omusawo wo okuzuula oba oli mu bulabe bw’okulwala ‘hungry bone syndrome’.
• Ebikolwa eby’okuziyiza:Bw’oba ​​oli mu bulabe obw’okulwala ‘hungry bone syndrome’, omusawo ayinza okukuwa amagezi okumira eddagala oba eddagala okukuuma omuwendo gwa vitamiini D ne kalisiyamu nga tonnalongoosebwa. Kino kiyinza okuyamba okukendeeza ku mikisa n’/oba obuzibu bw’obulwadde bwa ‘hungry bone syndrome’.
• Okulondoola oluvannyuma lw’okulongoosebwa: Oluvannyuma lw’okulongoosebwa, ttiimu y’eddwaliro ejja kukebera buli kiseera omuwendo gwa calcium, phosphate, magnesium ne PTH mu musaayi gwo. Kino kikolebwa singa ofuna obulwadde bwa ‘hungry bone syndrome’, busobola okuzuulibwa nga bukyali era obujjanjabi busobole okutandika amangu ddala.

Wabula wadde nga bino byonna bikoleddwa, oluusi ‘hungry bone syndrome’ esobola okukula. Abanoonyereza n’okutuusa kati tebakakasa lwaki kino kibaawo.

Nsaana okulaba omusawo ku ssaawa mmeka?

Bw’oba ​​olongooseddwa parathyroid oba thyroid n’oluvannyuma n’ofuna obubonero bwa calcium omutono mu musaayi (`(Hypocalcemia)`) bwe twayogeddeko emabegako, gamba ng’okuzimba ebinywa, okuwulira obunafu, enkyukakyuka mu kutegeera (nga okutabulwa), n’okuzimba emimwa n’engalo, mazima ddala wandibadde olaba omusawo amangu ddala nga bwe kisoboka.**Eggumba ly’omusulo syndrome' ne `(Hypocalcemia)` bisobola okubaawo oluvannyuma lw'okulongoosebwa parathyroid ne/oba thyroid, biyinza okukka oluvannyuma lw'ennaku ntono, n'oluvannyuma ne biddamu okulabika. N’olwekyo, kikulu nnyo okussaayo omwoyo ku kabonero akatono n’akatono.

‘Hungry bone syndrome’ mbeera eyinza okubaawo oluvannyuma lw’okulongoosebwa okuggyamu endwadde za parathyroid oba thyroid. Amawulire amalungi gali nti asobola okujjanjabibwa n’okuwona. Kyokka, kiyinza okutwala ekiseera okutereera mu bujjuvu. Okuva bwe kiri nti ekirungo kya calcium ekikendeera ennyo mu musaayi kiyinza okuba eky’obulabe eri obulamu bwo, kirungi okugenda ew’omusawo amangu ddala ng’olaba obubonero.

Twala awaka obubaka

Kale, mu ngeri ennyangu, ‘Hungry Bone Syndrome’ mbeera eyinza okubaawo oluvannyuma lw’okulongoosebwa ku parathyroid oba thyroid gland. Mu bukulu kye kikola kwe kuba nti omuwendo gwa kalisiyamu mu musaayi gw’omubiri gukendeera mangu. Kino kiri bwe kityo kubanga omutindo gw'obusimu obuyitibwa parathyroid hormone (`(PTH)`) gukendeera oluvannyuma lw'okulongoosebwa, ekivaako amagumba "okwetaaga" calcium.

Totya kuwulira bino, kubanga 'Hungry Bone Syndrome' mbeera esobola okujjanjabibwa n'okuwona obulungi ennyo.

Ekisinga obukulu, bw’oba ​​olina obubonero buno bwonna (nga okunyiga ebinywa, okukoowa, okuzirika), tomala biseera era olabe omusawo amangu ddala nga bwe kisoboka. Mu ngeri eno, osobola okuzuula embeera eno nga bukyali, n’otandika amangu obujjanjabi obwetaagisa, n’ogiwonya nga tebunnafuuka kizibu kinene. Jjukira nti okulabirira obulamu bwo kiri mu mikono gyo.

`Obulwadde bw’amagumba g’enjala, Obulwadde bw’amagumba g’enjala, Calcium, Hypocalcemia, Parathyroid, Okulongoosa thyroid, PTH