Obujjanjabi bw'okwennyamira: Omanyi empeke za Isocarboxazid?

Oluusi owulira ennaku ey’amaanyi, okweraliikirira oba ng’oboola obulamu? Mu busawo, embeera eno tugiyita ``Okwennyamira``. Kale, abasawo batuwa eddagala erimu okutuyamba mu biseera nga bino. Okugeza eddagala ery’enjawulo erikozesebwa okujjanjaba embeera eyitibwa okwennyamira ye ``Isocarboxazid``. ``Marplan`` lye linnya eddala eriyitibwa eddagala lino.

`Isocarboxazid` ddagala lya ngeri ki?

Mu ngeri ennyangu, `Isocarboxazid` ddagala eriyamba okukendeeza ku nnaku, okweraliikirira n'okulongoosa embeera yo. Obwongo bwaffe bulimu ababaka b’eddagala abayitibwa `Dopamine`, `Norepinephrine` ne `Serotonin`. Zino ze ddagala eriyamba okufuga enneewulira zaffe ez’essanyu n’ennaku. `Isocarboxazid` ekola nga eyongera ku miwendo gy'eddagala lino mu bwongo.

Eddagala lino liri mu kibinja ky'eddagala eriyitibwa `MAOI`. `MAOI` kitegeeza `Ebiziyiza Monoamine Oxidase`. Enziyiza eno (`Monoamine Oxidase`) emenya eddagala eryayogeddwako emabegako nga `Dopamine`, `Norepinephrine`, `Serotonin` mu mubiri gwaffe. Kale, olw’okuba eddagala lya `MAOI` liyimiriza emirimu gya enzyme eyo, eddagala eryo eddungi lisigala mu bwongo okumala ebbanga eddene. Ekyo kye kiyamba okukendeeza ku kweraliikirira. Naye n’abasawo basobola okumuwa eddagala lino ku ndwadde endala. Kale bw’oba ​​olina ekibuuzo kyonna, buuza omusawo wo oba omukugu mu by’eddagala.

Ebintu by’olina okubuulira omusawo nga tonnatandika ddagala lino

Nga tonnatandika kumira `Isocarboxazid`, waliwo ebintu ebitonotono by'osaanidde okutegeeza omusawo wo. Kubanga eddagala lino terisaanira buli muntu. N’olwekyo ebintu bino olina okubibuulira omusawo wo mu bwesimbu ennyo.

• Olina obulwadde bw'amaaso `Glaucoma`?
• Otera okulumwa omutwe oba omutwe omuzito?
• Olina obulwadde bw’omutima?
• Olina puleesa?
• Obaddeko omutima ogukuba mu ngeri etaali ya bulijjo?
• Obadde ofunye stroke emabegako?
• Oli munywa mwenge bulijjo?
• Olina obulwadde bw’ekibumba?
• Olina obulwadde bw’ekibumba?
• Waliwo endwadde endala zonna ez’obwongo?
• Waliwo embeera ya kookolo ey’endwadde z’ekibumba eyitibwa `Pheochromocytoma`?
• Gye buvuddeko wali ofunye obuvune ku mutwe (head trauma)?
• Waliwo okukonziba kwonna?
• Wali obadde n’ebirowoozo eby’okwetta, enteekateeka, oba okugezaako okwetta emabegako? Waliwo omuntu yenna mu maka go akoze bw’atyo?
• Olina allergy eri eddagala `Isocarboxazid`, eddagala eddala, emmere, langi, oba ebikuuma?
• Oli lubuto oba ogezaako okufuna olubuto?
• Oli maama ayonsa?

Singa ekimu ku bino kikukwatako, kikulu nnyo okutegeeza omusawo wo.

Eddagala lino nkozese ntya?

Eddagala lino lijja mu ngeri y’empeke. Kirina okumira mu kamwa n’egiraasi y’amazzi. Kirungi okugimira ng’omusawo bw’akulagidde, mu kiseera kye kimu buli lunaku. Sigala ng’omira eddagala lino okutuusa omusawo lw’akugamba nti okomye.

Edduuka ly’eddagala bwe likuwa eddagala lino, likuwa n’akatabo k’ebiragiro ak’enjawulo (a `MedGuide`). Olina okusoma obulungi `MedGuide` eno buli lw'omira eddagala ne bw'okyusa eccupa y'eddagala. Kirimu amawulire amakulu ennyo agakwata ku ddagala lino.

Jjukira: Eddagala lino lya ggwe wekka. Togabana ddagala lyo na balala, ne bwe baba nga balina obubonero bwe bumu naawe.

Bw’oba ​​ogaba eddagala lino eri abaana abato, olina okufaayo ennyo. N’olwekyo, yogerako n’omusawo wo ku nsonga eno ofune amagezi.

Bw’oba ​​olowooza nti mu butanwa wamira eddagala lino erisukkiridde, genda mu kitongole ky’abalwadde ab’amangu mu ddwaaliro ekikuli okumpi, oba kuba ku ssimu y’ekifo ekirwanyisa obutwa, awatali kulwa.

Kiki ky’olina okukola singa osubwa ddoozi y’eddagala?

Bw’oba ​​weerabira okumira ddoozi, gimira amangu ddala ng’ojjukira. Wabula bwe kiba nti kumpi ekiseera kya ddoozi yo eddako, buuka ddoozi gy’osubiddwa era onywe ddoozi yo eddako mu kiseera ky’otegese. Tomirangako ddoozi bbiri omulundi gumu. Okukola ekyo kiyinza okwongera ku ddoozi.

Ebintu ebirala ebiyinza okukwatagana n’eddagala lino (interactions) .

Kino kintu kya kwegendereza nnyo . Eddagala lya `Isocarboxazid` liyinza okukwatagana obubi nnyo n'emmere ezimu n'eddagala eddala. Kino kiyinza okuvaako ebizibu eby’obulabe.

Weewale emmere erimu `Tyramine`!

Si kirungi okulya emmere erimu eddagala eringi erya tyramine ng’omira `Isocarboxazid`. Singa bino byombi bigattibwa wamu, embeera eziteeka obulamu mu matigga ng’okulumwa omutwe okw’amaanyi okw’amangu, puleesa (`Hypertensive crisis`), oba omutima okukuba obutasalako bisobola okubaawo.

Mmere ki erimu ekirungo kya `Tyramine` ekingi?

• Cheese ezikaddiye
• Ennyama erongooseddwa - ebintu nga sosegi, salami, pepperoni
• Bbiya ne ale (ne bbiya atali wa mwenge) .
• Wine (naddala wayini omumyufu), sherry
• Omwenge omukalu, Liqueurs
• Ovakedo
• Ebijanjaalo (naddala ebikungudde obulungi) .
• Ettiini, Zabbibu
• Soya sauce, ssupu wa Miso
• Ebizimbulukusa/ebirungo ebiva mu puloteyina
• Tofu (Omubisi gw’ebinyeebwa) .
• Fava oba ebikoola by’ebinyeebwa ebigazi
• Ebibala byonna ebisusse okwengera

Olukalala luno terujjuvu, n’olwekyo saba omusawo wo, omukugu mu by’eddagala oba omukugu mu by’endya olukalala lw’emmere mu bujjuvu erimu ekirungo kya tyramine.

Ate era, kirungi okussa ekkomo ku byokunywa ebirimu caffeine (nga caayi, kaawa, chocolate, ne cola) ng’omira eddagala lino.

Buuza omusawo wo ebbanga ly’osaanidde okwewala emmere n’ebyokunywa bino ng’omaze okulekera awo eddagala lino.

Eddagala eritalina kumira n’eddagala lino

Eddagala lino wammanga liyinza okuleeta ebizibu eby’amaanyi ennyo singa limira wamu ne `Isocarboxazid`. N’olwekyo, bw’oba ​​mu kiseera kino omira eddagala lino, olina okutegeeza omusawo wo.

• Eddagala lya Atomoxetine
• `Buspirone`
• `Eddagala lya Carbamazepine`
• Eddagala erimu erya puleesa: `Guanabenz`, `Guanadrel`, `Guanethidine`, `Reserpine`
• `Cocaine`
• `Eddagala lya Cyclobenzaprine`
• Dextromethorphan (alimu ebizigo ebimu eby’okusesema) .
• Eddagala erikendeeza ku mugejjo oba eddagala erizimba: Amphetamines, Ephedra
• `Diphenoxylate`
• `Effedrine`
• Eddagala eribudamya abantu bonna oba mu kitundu (bw’oba ​​omira eddagala lino nga tonnalongoosebwa, olina okutegeeza omusawo wo ) .
• `Genseng`
• Green tea (okunywa ennyo) .
• `Guarana`
• Linezolid (eddagala eritta obuwuka) .
• Ebika ebirala ebya `MAOI`: `Phenelzine` (phenelzine), `Rasagiline` (rasagiline), `Safinamide` (safinamide), `Selegiline` (selegiline), `Tranylcypromine` (tranylcypromine) .
• Eddagala eriwonya omutwe ogulumwa omutwe
• Eddagala eriwonya obuzibu mu ntambula nga obulwadde bwa Parkinson: `Entacapone`, `Levodopa`, `Selegiline`, `Tolcapone`
• Meperidine (eddagala eriweweeza ku bulumi) .
• `Bbululu wa methylene`
• Eddagala eriweweeza ku kweraliikirira okulala, okweraliikirira oba ebizibu by’embeera y’omuntu
• Eddagala eriweweeza ku bulumi eriwandiikiddwa abasawo
• `Eddagala lya Procarbazine`
• `SAM-e`
• `Omutukuvu. John's Wort` (eddagala ly'omuddo abantu abamu lye bamira okusobola okubeera obulungi mu bwongo)
• `Tramadol` (eddagala eriweweeza ku bulumi) .
• `Tryptophan`
• Tyramine (esangibwa mu mmere era ayinza n’okusangibwa mu bimu ku bikozesebwa) .
• `Eddagala lya Viloxazine`
• `Yohimbine`

Eddagala eddala eriyinza okukwatagana n’eddagala lino

Eddagala lino wammanga nalyo liyinza okukwatagana ne `Isocarboxazid`. N’olwekyo, bw’oba ​​omira bino, buulira omusawo wo nabyo.

• Ebirungo ebiyitibwa barbiturates (e.g. Phenobarbital) .
• Eddagala erifulumya amazzi mu mubiri
• Isoniazid (eddagala eriwonya akafuba) .
• Eddagala eriwonya obubonero ng’omusujja, alergy, ne ssennyiga
• Eddagala eriwonya obulwadde bwa sukaali
• Eddagala mu kibinja kya `Phenothiazines` (e.g. `Chlorpromazine`, `Prochlorperazine`, `Thioridazine`)

Olukalala luno terunnaggwa. Kale buulira omusawo wo ku ddagala lyonna ly’omira (eriwandiikiddwa, eritali ku ddagala, ery’ebimera, erya vitamiini, ery’endya). Era buulira omusawo wo bw’oba ​​onywa sigala, onywa omwenge oba okozesa eddagala eddala. Ebintu ebimu bisobola okukwatagana n’eddagala lino.

Ebintu ebirala by’olina okwegendereza ng’omira eddagala lino

• Singa obubonero bwo tebutereera oba nga bulabika nga bweyongera, buulira omusawo amangu ago. Sigala ng’okwatagana n’omusawo wo olabe engeri eddagala gye likola. Eddagala lino liyinza okutwala wiiki eziwerako okukola mu bujjuvu. N’olwekyo kikulu okugenda mu maaso n’okumira obujjanjabi nga omusawo bw’akugamba.
• Okulowooza ku kwetta oba okwennyamira okweyongera: Kino kikulu nnyo . Bw’oba ​​omira eddagala lino naddala ng’otandika obujjanjabi oba ng’omaze okukyusa ddoozi, weetegereze nnyo ebirowoozo byo okulaba oba olaba ebirowoozo ebipya eby’okwetta oba okwennyamira okweyongera. Ate era bw’oba ​​olina enkyukakyuka yonna ey’amangu mu muudu yo, gamba ng’okuwulira nga weeraliikirira, nga toteredde, ng’onyiiga, ng’olina obulabe, ng’olina obusungu, mukakanyavu, nga toteredde nnyo, ng’oyitiridde okutabuka n’okukola ennyo, oba ng’olina obuzibu mu tulo, kuba essimu y’omusawo amangu ago. Buulira ab’omu maka go era obasabe nabo batunuulire enkyukakyuka zino.
• Oyinza okuwulira ng’otulo oba ng’oziyira. Kale, okutuusa lw’onoomanya engeri eddagala lino gye likukwatamu, tovuga, tokozesa byuma, oba okukola ekintu kyonna ekyetaagisa okussaayo omwoyo. Tosituka oba okutuula mangu naddala ng’okaddiye. Bw’okikola kijja kukendeeza ku mikisa gy’okuziyira n’okugwa.
• Omwenge guyinza okutaataaganya eddagala lino okukola obulungi, n’olwekyo weewale okunywa omwenge.
• Eddagala lino liyinza okuvaako amaaso okukala n’okulaba obubi. Bw’oyambala lenzi, oyinza okufuna obuzibu. Okusiiga amatondo g’amaaso kiyinza okuyamba. Ekizibu kino bwe kisigala oba nga kya maanyi, laba omusawo w’amaaso.
• Akamwa akakalu kayinza okuba ekizibu. Okukamula ggaamu ataliimu ssukaali, okunuuna ssweeta enkalu etaliimu ssukaali n’okunywa amazzi amangi bisobola okuyamba. Ekizibu kino bwe kisigala oba ne kifuuka eky’amaanyi, yogerako n’omusawo wo.
• Weebuuze ku musawo nga tonnamira ddagala lyonna ery’okwekolako ku bintu ng’okusesema, omusujja, ne alergy. Ekirala, tomira ddagala lyonna erikendeeza ku mugejjo nga tolina lukusa lwa musawo. Ebirungo ebiri mu bimu ku bintu bino biyinza okwongera ku bizibu ebivaamu.
• Eddagala lino liyinza okukosa ssukaali mu musaayi. Bw’oba ​​olina obulwadde bwa sukaali, yogerako n’omusawo wo nga tonnakyusa mmere yo oba ddoozi y’eddagala lyo erya sukaali.
• Bw’oba ​​ogenda kulongoosebwa kwonna, okukeberebwa kw’abasawo oba okulongoosebwa, tegeeza omusawo wo nti omira eddagala lino. Eddagala lino litera okwetaaga okuyimirizibwa ng’ebula ennaku nga 10 okulongoosebwa mu ngeri ey’okulonda.
• Eddagala lino liyinza okuvaako vitamiini B6 okubeera entono. Kale kakasa nti ofuna vitamiini B6 emala ng’omira eddagala lino. Yogerako n’omusawo wo ku mmere ne vitamiini z’omira.

Biki ebiyinza okuva mu ddagala lino?

Okufaananako n’eddagala lyonna, Isocarboxazid asobola okuleeta ebizibu mu bantu abamu. Ebimu bya siriyaasi, ebimu si bya maanyi nnyo.

Ebizibu by’osaanidde okutegeeza omusawo mu bwangu:

Bw’ofuna obubonero buno bwonna, tegeeza omusawo wo awatali kulwa :

• Allergy : Okusiiyibwa ku lususu, okusiiwa, amabala amamyufu ku lususu, okuzimba mu maaso, emimwa, olulimi oba emimiro.
• Obubonero bwa Serotonin Syndrome : Okunyiiga, okutabulwa, omutima okukuba amangu oba obutasalako, ebinywa okukaluba oba okunyiganyiga, okutuuyana ennyo, omusujja ogw’amaanyi, okukonziba, okuziyira, okusiiyibwa, ekiddukano. Bino biyinza okuba obubonero bw’embeera ey’akabi eyitibwa Serotonin Syndrome, kubanga eddagala lino lyongera ku muwendo gwa serotonin mu bwongo.
• Obubonero bw’okulumwa ekibumba : Obulumi mu lubuto olwa waggulu ku ddyo, obutayagala mmere, okuziyira, omusulo ogwa langi enzirugavu, omusulo ogwa kyenvu oba kitaka enzirugavu, olususu oba amaaso okufuuka kyenvu, obunafu oba obukoowu obutali bwa bulijjo.
• Puleesa entono : Okuziyira, okuzirika, obutalaba bulungi.
• Okukonziba .
• Puleesa okweyongera ennyo : Okutandika amangu omutwe ogw’amaanyi, okuziyira, okusiiyibwa, okukaluba kw’ensingo, omutima okukuba amangu oba mu ngeri etategeerekeka (kino kiyinza okuba akabonero k’okuddamu kwa `Tyramine`).
• Ebirowoozo by’okwetta oba okwetuusaako obulabe, embeera y’omuntu okwonooneka, n’okwennyamira okweyongera .

Ebizibu ebitera obutaba bya bulabe nnyo, naye nga birina okuloopebwa eri omusawo singa bibaawo:

Ebiseera ebisinga ebizibu bino si bya maanyi, naye bwe bisigala nga bikutawaanya oba bikutawaanya, tegeeza omusawo wo:

• Obuteeyabya
• Okuziyira
• Akamwa akalu
• Okulumizibwa omutwe
• Ekikeeto
• Okukankana

Bw’olaba obubonero bwonna obutali bwa bulijjo oba obupya ng’omira eddagala lino obutali ku lukalala, tegeeza omusawo wo. Osobola n’okuloopa ebizibu ebivaamu eri FDA ku 1-800-FDA-1088.

Eddagala lino otereka otya?

• Eddagala lino likuume nga baana n'ebisolo by'omu nnyumba tebisobola kutuuka .
• Teeka ku bbugumu erya bulijjo (wakati wa diguli 15 ne 30 / diguli 59 ne 86 eza Fahrenheit). Eccupa/ekipapula ky’eddagala kikuume nga kiggaddwa bulungi .
• Tokozesa ddagala liweddewo. Zisuule.

Engeri y’okusuula eddagala eritakozesebwa oba eriweddeko:

• Waliwo pulogulaamu z’okutwala eddagala. Osobola okubamanya ku dduuka lyo ery’eddagala oba ku poliisi.
• Ekyo bwe kiba tekisoboka, kebera ku lupapula lw’eddagala oba olupapula oluli munda olabe oba lulina okusuulibwa mu kasasiro oba okukulukutira wansi mu kaabuyonjo. Bw’oba ​​tokakasa, buuza omusawo wo.
• Bwe kiba nga tekirina bulabe kusuula mu kasasiro, ggyayo eddagala mu kibbo. Kitabule n’ekintu ekirala, gamba ng’ebisasiro by’embwa, ettaka oba ebikuta bya kaawa. Omutabula guteeke mu nsawo oba mu kibbo, gusibe bulungi, ogusuule mu kasasiro.

N’ekisembayo, ebintu by’olina okujjukira

`Isocarboxazid` ddagala ddene nnyo mu kujjanjaba ekiwuubaalo. Naye olw’okuba kiri mu kibiina kya `MAOI`, kiyinza okuleeta enkolagana ey’amaanyi n’emmere (naddala emmere erimu `Tyramine`) n’eddagala eddala.

Nga bw’omira eddagala lino, weegendereze nnyo enkyukakyuka mu muudu yo naddala ebirowoozo by’okwetta. Bw’oba ​​olina ekizibu kyonna, tegeeza omusawo amangu ago. Ddira ddoozi entuufu, mu kiseera ekituufu, nga omusawo wo bw’akugamba ddala. Olwo lwokka w’osobola okufunamu ekisingawo mu ddagala lino n’okulongoosa obulamu bwo obw’omutwe.

Ekitundu kino kifunze kyokka. Bw’oba ​​olina ekibuuzo ekirala kyonna ku ddagala lino, nsaba oyogere n’omusawo wo, omukugu mu by’eddagala oba omusawo omulala.

` Isocarboxazid, MAOI, okwennyamira, obulamu bw’obwongo, dopamine, serotonin, tyramine, ebizibu ebivaamu, enkolagana y’eddagala