Waliwo obuzibu mu nkola y’amasannyalaze g’omutima gwo? Ka twogere ku bulwadde bwa Long QT Syndrome (LQTS).

Wali owuliddeko ku nkola y’amasannyalaze g’omutima? Omutima gwaffe gukola ng’ekyuma ekitono. Alina enkola y’amasannyalaze, efuga okukuba kw’omutima. Oluusi, enkyukakyuka entonotono zisobola okubaawo mu nkola eno ey’amasannyalaze. Enkyukakyuka emu ng’ezo eyitibwa Long QT Syndrome, oba `(Long QT Syndrome - LQTS)`. Tofaayo, ka twogere ku nsonga eno mu ngeri ennyangu.

Obulwadde bwa Long QT Syndrome kye ki? Mu ngeri ennyangu...

Teebereza nti omutima gwo bwe gumala okukuba omulundi gumu, gutwala "okuwummula" katono nga tegunnaddamu kukuba, nga bbaatule bw'eddamu okucaajinga. Obudde obutwala "okuwummula" oba okuddamu amaanyi buwanvu katono okusinga ku bwa bulijjo, kye tuyita long QT syndrome.

Bw’oba ​​obadde okola ECG, nga kino kye kigezo ekitunuulira amasannyalaze g’omutima, waliwo ekitundu ku kyo ekiyitibwa QT interval. Kino kiraga ebbanga lye kitwala ebisenge ebya wansi eby'omutima gwo ebiyitibwa ventricles okukwatagana n'oluvannyuma ne biwummulamu, oba "okuddamu amaanyi" nga bwe nnagambye.

Omulimu gw’amasannyalaze ogw’omutima gwaffe guyambibwako obutundutundu obutono obulina amasannyalaze obuyitibwa `ions`. Ayoni nga sodium, calcium, potassium, ne chloride bye biyamba mu kino. Ayoni zino ziyingira ne zifuluma mu butoffaali bw’omutima nga ziyita mu mikutu egy’enjawulo egiyitibwa `emikutu gya ion`. Kati, mu kino `(Long QT Syndrome)`, oba waliwo obuzibu ku mikutu gino egya ion, oba waliwo obutabaawo. Olwo omutima ne gulwawo "okuddamu okucaajinga". Ekiseera kya QT bwe kiwanvuwa, wabaawo obulabe obweyongera obw’obuzibu bw’okukuba kw’omutima obw’amangu obw’akabi obuyitibwa `Torsades de Pointes`, obuyinza okutta obulamu.

Waliwo ebika by’obulwadde bwa Long QT Syndrome?

Yee, waliwo ebika bibiri ebikulu. Ekimu kisikira , ekitegeeza nti kiyisibwa okuyita mu buzaale. Ekirala kifunibwa , ekitegeeza nti kiva ku bintu ebirala, gamba ng’eddagala erimu.

Ebika by’obuzaale:

Bino bisinga kuva ku buzibu mu buzaale mu `ion channels` ze njogeddeko.

• Obutabeera bulungi mu mikutu gya ion: Kino kye kika ekisinga okubeerawo. Waliwo ebika ebiwerako nga `LQT1, LQT2, LQT3, LQT4, LQT5`. Zino zigabanyizibwa okusinziira ku kika ky’omukutu gwa ion oguzingirwamu. Obulabe bw’okulwala omutima mu biseera eby’omu maaso buyinza okwawukana okusinziira ku kika.
• Jervell ne Lange-Nielsen Syndrome: Mu mbeera eno, abazadde bombi basobola okutambuza obuzaale obutali bwa bulijjo, naye bayinza obutaba na bubonero. Eno mbeera ya bbula nnyo. Olw’okuba tekisuubirwa nti abazadde bombi bajja kutambuza obuzaale buno, buli mwana alina emikisa 25% okubusikira. Abantu abalina obulwadde buno bayinza okuzaalibwa nga bakiggala.
• Obulwadde bwa Romano-Ward Syndrome:Mu mbeera eno, omuzadde omu atera okuba n'obulwadde bwa ``Long QT Syndrome'' ate omulala talina. Buli mwana alina emikisa 50% okusikira obuzaale buno obutali bwa bulijjo. Mu mbeera eno, okuwulira kwa bulijjo.
• Timothy Syndrome: Kino nakyo kika kya bbula nnyo. Tekisobola kukosa mutima gwokka, wabula n’ebitundu by’omubiri ebirala.

Embeera eno ya bulijjo etya?

Long QT Syndrome mu butuufu mbeera etali ya bulijjo . Ng’ekyokulabirako, mu Amerika, kiteeberezebwa nti omuntu omu ku buli bantu 2,000 alina embeera eno.

Bubonero ki obulaga obulwadde bwa Long QT Syndrome?

Buno bwe bubonero obutera okulabibwa:

• Syncope: Okubulwa amagezi mu bwangu.
• Okukonziba: Abantu abamu bayinza okukonziba.
• Omutima okusiba: Kino kya bulabe nnyo.
• Okufa okw’amangu:

Obubonero buno bubaawo ng’obuzibu bw’omutima obw’akabi obuyitibwa `Torsades de Pointes` bwe nnayogeddeko emabegako bubaawo. Mu kiseera kino omutima tegusobola kusiba musaayi bulungi. Singa obwongo tebufuna musaayi gumala, ebintu ng’okuzirika n’okukonziba bibaawo. Singa obuzibu buno bweyongera, okufa okw’amangu kuyinza okubaawo. Kyokka singa omutima guddamu okukuba mu mbeera eya bulijjo, obubonero bukoma.

Obubonero businga kulabika nga:

• Nga okola dduyiro (oba eddakiika ntono oluvannyuma lw’okukola dduyiro).
• During strong emotional stimulation , naddala nga otidde mu bwangu oba nga weewuunya.
• Mu kiseera ky'okwebaka oba ng'ozuukuse mu bwangu .

Ekikulu, okutuuka ku 50% ku bantu abalina Long QT Syndrome bayinza obutafuna bubonero . Era, ku bantu nga omu ku buli bantu kkumi, omutima okusiba kye kabonero akasooka ak’embeera eno. Kino kiyinza okutta omuntu singa tekijjanjabwa mangu.

Obubonero butera okutandika mu myaka egy'obukulu . Bw’oba ​​olina obubonero, buyinza okuddamu. Obubonero businga kulabika nga tebannaweza myaka 30. Kyokka abantu abamu bayinza okufuna obubonero nga bali mu myaka 50 n’okusingawo.

Kiki ekivaako obulwadde bwa Long QT Syndrome?

Nga bwe nnagambye emabegako, kino kiyinza okusikira bazadde bo (congenital) oba okukifuna olw’eddagala erimu . Mu Long QT Syndrome, waliwo obutali bwa bulijjo mu gene code y’emikutu gyo egya ion. Emikutu gino egya ion egitali gya bulijjo gireeta okulwawo mu mutendera gw’okudda engulu kw’okukuba kw’omutima gwo. Kino kiyinza okuvaako obulwadde bw’okutambula kw’omusaayi mu ngeri eyinza okutta omuntu.

Eddagala erimu liyinza okuleeta ``Long QT Syndrome'' mu bantu abalina obusobozi obumu eri emikutu gyabwe egya ion. Bayinza n'obutakimanya, naye bwe bamira eddagala eryo ``Long QT'' w'ebaawo.

Eddagala eriyinza okuleeta obulwadde bwa acquired long QT syndrome:

• Ebimu ku `Antiarrhythmics` (eddagala eriwonya obuzibu bw'okukuba omutima)
• Ebimu ku ddagala eriweweeza ku kweraliikirira
• Eddagala erimu erifulumya omusulo (eddagala erikufuula omusulo ennyo) .
• Eddagala erimu eritta obuwuka
• Ebiziyiza oba ebiziyiza ebikwata ku serotonin
• Ebiziyiza ebikwata ku histamine

Ebirala ebivaako obulwadde bwa acquired long QT syndrome:

• Ebika by’obutwa ebimu
• Anorexia nervosa (obulwadde bw’obwongo obukwatagana n’obutafaayo) .
• Ebimu ku `bradyarrhythmias` (omutima okukuba empola mu ngeri etaali ya bulijjo) .
• Ebirungo bya calcium, magnesium oba potassium ebitono mu mubiri
• Obuvune ku busimu bwo

Ani ali mu bulabe obw’amaanyi obw’okufuna embeera eno?

Abantu bano wammanga bali mu bulabe bwa maanyi obw'okulwala ``Long QT Syndrome``:

• Ku baana abatawulira okuva lwe bazaalibwa.
• Abaana n‟abavubuka abalina ebyafaayo by‟amaka eby‟okufa okw‟amangu oba okuzirika (syncope) mu ngeri etategeerekeka.
• Ku abooluganda lw'omusaayi abalina ``Long QT Syndrome``.
• Ku abo abalina `Cardiomyopathy` (obulwadde bw'ebinywa by'omutima) oba obulwadde bw'omutima obuzaalibwa.
• Ku abo abalina obusannyalazo obumu obutono mu mubiri olw’embeera endala ey’obujjanjabi.
• Ku abo abamira eddagala erikosa emikutu gya ion mu mutima.

Nze era nsaana okukeberebwa obulwadde bwa Long QT Syndrome?

Long QT Syndrome mbeera ya buzaale esobola okusiigibwa okuva ku mulembe okudda ku mulala. Singa omu ku b’eŋŋanda zo eza ddaala erisooka (abazadde, baganda bo, abaana) alina obulwadde bwa Long QT Syndrome, kirungi okukeberebwa obuzaale .

Abooluganda bonna aba ddaala erisooka (abooluganda, abazadde, n’abaana) balina okukeberebwa ECG. Era kikulu omuntu yenna alina ebyafaayo by’amaka eby’okukonziba oba okuzirika okukeberebwa kuno.

Ekisooka kwe kutegeeza omusawo wo nti ab’omu maka go balina embeera eno. Kirabika ajja kukola ebigezo ebyetaagisa okukebera omutima gwo. Singa ebigezo ebyo bikakasa nti olina embeera eno, olina okugenda ew’omusawo w’omutima ng’amanyi bulungi obulwadde bwa Long QT Syndrome.

Bizibu ki ebiva mu bulwadde bwa Long QT Syndrome?

``Long QT Syndrome`` esobola okuleeta obulwadde bw'okutambula obulungi obutta obulamu obuyitibwa ``Torsades de Pointes`` bwe nnayogeddeko. Kino kiyinza n’okuviirako okufa okw’amangu.

Obulwadde bwa Long QT Syndrome buzuulibwa butya?

Abasawo basobola okuzuula obulwadde bwa Long QT Syndrome nga bakozesa okukebera kwa ECG okwangu. Okuzuula embeera eno, bapima QT interval ku ECG. Singa QT interval yo esukka milisekondi 450, oyinza okuba n’obulwadde bwa Long QT Syndrome.

Omusawo ajja kukubuuza ku bintu bino:

• Waliwo ebyafaayo by'amaka eby'obulwadde bwa ``Long QT Syndrome''?
• Waliwo ebyafaayo by’amaka eby’okuzirika, okukonziba oba okusiba omutima mu ngeri etategeerekeka?
• Wali ozirika, okukonziba oba okusiba omutima naddala ng’okola dduyiro?

Bikebere ki ebikozesebwa okuzuula obulwadde bwa Long QT Syndrome?

Ng’oggyeeko ECG, okukebera kuno kuyinza n’okukolebwa:

• Okukebera omusaayi.
• Okukebera obuzaale.
• Okugezesa situleesi mu dduyiro.
• Ambulatory monitor: Kino erondoola enkola y’omutima gwo okumala ennaku eziwera.

Obulwadde bwa Long QT Syndrome bujjanjabwa butya?

Waliwo eddagala, ebyuma, oba okulongoosa ebiyinza okuyamba okufuga obubonero n’okuziyiza okufa okw’amangu olw’obulwadde bwa Long QT Syndrome. Wadde ng’obujjanjabi buno tebusobola kuwonya mbeera eno ddala, busobola okukukuuma obutakuba mutima mu ngeri etaali ya bulijjo.

Eddagala

Abantu bangi abalina obulwadde bwa Long QT Syndrome (ne abo abatalina bubonero) bamira eddagala eriziyiza obulwadde bwa beta-blocker, nga nadolol. Eddagala eddala liyinza okukendeeza ku QT interval yo oba okulongoosa electrolyte levels yo. Omusawo ajja kukubuulira eddagala erisinga okukukwatako.

Ebyuma ebikozesebwa

Abalwadde abamu abalina ``Long QT Syndrome'' nabo bayinza okwetaaga ebyuma nga bino:

• Implantable Cardioverter Defibrillator (ICD): Ekyuma ekiziyiza omutima ekiyitibwa implantable cardioverter defibrillator (ICD) kiyinza okuteekebwa mu bantu abalina ebyafaayo by’okusiba omutima oba abakyalina obubonero wadde nga bafunye obujjanjabi bwa beta-blocker. Ekyuma kino kizuula obuzibu bw’okutambula kw’omusaayi mu mutima oguyinza okutta omuntu era ne kituusa ekiwujjo ku mutima mu ngeri ey’otoma okutangira okufa okw’amangu.
• Pacemaker: Ekyuma kino kiyamba abantu abalina omutima okutambula empola mu ngeri etaali ya bulijjo.

Okuloongoosa

Abalwadde abamu abalina obulwadde bwa Long QT Syndrome bayinza okwetaaga okulongoosebwa Left Cardiac Sympathetic Denervation (LCSD) oba sympathectomy. Eno nkola etali ya kuyingirira nnyo nga mu busimu obumu mu busimu bwo obw’okusaasira buggyibwamu.

Bizibu ki/ebizibu ebiva mu bujjanjabi bye biruwa?

Ebizibu oba ebizibu ebiyinza okuvaamu bisinziira ku kika ky’obujjanjabi bw’ofuna.

• Omuzibizi wa Beta:
• Puleesa eya wansi.
• Okuziyira.
• Okulumizibwa omutwe .
• Obukoowu.
• ICD (Ekyuma ekiziyiza omutima ekiteekebwa mu mubiri):
• Ensobi mu kyuma.
• Amawuggwe agagudde.
• Okuvaamu omusaayi.
• Yinfekisoni.
• Ekyuma ekikuba omukka:
• Amawuggwe agagudde.
• Okuvaamu omusaayi.
• Yinfekisoni.
• Ensobi mu kyuma.
• LCSD (Okulongoosa okukendeeza ku busimu bw’omutima obw’okusaasira):
• Obulwadde bwa Horner.
• Amawuggwe agagudde.
• Okumyuuka mu maaso oba okutuuyana.

Obulwadde bwa Long QT Syndrome busobola okuziyizibwa?

Tosobola kukiremesa singa okisikira ku bazadde bo. Wabula eri abo abatabusikira, osobola okuziyiza embeera ezireeta acquired (long QT syndrome) oluvannyuma. Ng’ekyokulabirako, weegendereze ku ddagala erimu.

Kiki ekibaawo singa mba n’obulwadde bwa Long QT Syndrome?

With proper treatment , omuwendo gw'okufa kw'abantu abalina ``Long QT Syndrome`` guli nga 1%. Awatali bujjanjabi, embeera eba mbi nnyo. Abantu nga 21% abalina obubonero abatafuna bujjanjabi bafa mu mwaka gumu bukya bulwadde bwa syncope butandise.

Naye jjukira, abantu abalina ``Long QT Syndrome'' basobola okubeera obulamu obujjuvu . Basobola okufuna embuto ne bazaala abaana.

Obulwadde bwa Long QT Syndrome bumala bbanga ki?

Inherited Long QT Syndrome mbeera ya bulamu bwonna. Wabula obubonero n’obulabe bw’okufuna ebizibu biyinza okukendeera oluvannyuma lw’ekiseera.

Nze nneerabirira ntya?

Long QT Syndrome esobola okukosa ebintu bingi mu bulamu bwo obwa bulijjo. Olina okwebuuza ku musawo nga tonnaba kukola bintu bimu.

Amaloboozi n’okunyigirizibwa

Abantu abamu abalina obulwadde bwa Long QT Syndrome bayinza okukosebwa amaloboozi amangi ag’amangu oba situleesi mu nneewulira. Wadde nga tosobola kufuga maloboozi gonna na situleesi ekubeetoolodde, osobola okugezaako okubikomya.

• Gamba mikwano gyo n’ab’omu maka go nti si kya bulabe kukuzuukusa mu bwangu.
• Mu kifo ky’okukozesa alamu ey’amaanyi evuga omulundi gumu, kozesa alamu erimu eddoboozi erisanyusa.
• Kendeeza ku ddoboozi ly’ebintu ebinene ebiyinza okukuwuniikiriza.

Dduyilo

Ebika ebimu eby’obulwadde bwa Long QT Syndrome bitera okuleeta obuzibu mu dduyiro. Omusawo ajja kukubuulira emirimu egikusaanira okusinziira ku kika ky’obuzaale obutali bwa bulijjo bw’olina. Olw’okuba dduyiro asobola okuvaako okutabuka kw’omusaayi okufa, olina okwogera n’omusawo wo nga tonnasalawo kuzannya mizannyo egy’okuvuganya. Bw’oba ​​osazeewo okuzannya emizannyo, kiyinza okwetaagisa okukola ebintu ebimu eby’okwekuuma.

Okuwuga kuyinza okuba okw'akabi eri abantu abamu abalina ``Long QT Syndrome''. Singa ozirika ng’owuga, oyinza okubbira mu mazzi.

Eddagala

Eddagala lingi liyinza okwongera ku bbanga lya QT. Eddagala lino liyinza okukosa abantu abalina ``Long QT Syndrome`` okusinga abo abatalina. Bwoba olina ``Long QT Syndrome``, olina okukola bino wammanga:

• Buulira abasawo bo bonna nti olina ``Long QT Syndrome''.
• Yogerako n’omusawo wo nga tonnamira ddagala lyonna eriragiddwa ku mbeera endala ez’obujjanjabi.
• Weewale okumira eddagala eritali ku ddagala (OTC) (okuggyako aspirin oba paracetamol eya bulijjo) nga toyogedde na musawo wo.

Bwoba olina ``Long QT Syndrome'', ebika by'eddagala bino biyinza okukukosa:

• Antihistamines (eddagala eriwonya alergy) .
• Eddagala eriweweeza ku kweraliikirira (eddagala eriwonya okwennyamira) .
• Eddagala eriwonya ebizibu by’obwongo
• Eddagala eriwonya endwadde z’omutima
• `Eddagala eritta obuwuka`
• Eddagala eritta obuwuka obuleeta endwadde
• `Eddagala eritta akawuka`
• Eddagala eriwonya endwadde z’ekyenda
• Eddagala eriweweeza ku kuzimba
• Diuretics (eddagala erivaako okufulumya omusulo okweyongera) .
• Eddagala eriwonya puleesa
• Eddagala eriwonya omutwe omuzito
• Eddagala erikendeeza ku kolesterol

Ddi lwe nnina okulaba omusawo wange?

Olina okulaba omusawo ng’otandika okufuna obubonero ate waakiri omulundi gumu mu mwaka oluvannyuma lw’ekyo. Omukugu mu by’amasannyalaze y’asinga obulungi.

Singa omwana wo alina ``Long QT Syndrome'', olina okulaba omusawo wo emirundi egisukka mu gumu mu mwaka okukakasa nti afuna ddoozi y'eddagala entuufu okusinziira ku buzito bw'alina kati.

Bw’oba ​​olina ekyuma ekikuteekeddwamu, olina okulaba omusawo omulundi gumu mu mwaka okukakasa nti kikola bulungi.

Ddi lwe nnina okugenda mu kitongole ekijjanjaba abalwadde ab’amangu (ETU) ?

Omuntu alina obulwadde bw'omutima yeetaaga okujjanjabibwa mu bwangu . Omuntu ali okumpi alina okutandika CPR (okuzuukusa omutima) n’akubira 911 (oba ennamba yo ey’amangu mu kitundu kyo).

Bibuuzo ki bye nnina okubuuza omusawo wange?

Ebimu ku bibuuzo by’oyinza okubuuza omusawo wo:

• Kika ki ekya ``Long QT Syndrome'' kye nnina?
• Bujjanjabi ki obw’enjawulo bw’onteesa?
• Mirundi emeka gye nneetaaga okukulaba?
• Eddagala ki n'emirimu ki gye nsaanidde okwewala n'ekika kyange ekigere ekya ``Long QT Syndrome''?

N’ekisembayo, Obubaka bw’Okutwala Awaka

Kya bulijjo okuwulira okweraliikirira ng’okizudde nti olina obulwadde bw’omutima. Naye okubuuza omusawo ebibuuzo era bwe kiba kyetaagisa okwogera n’omubuulirizi kiyinza okukuyamba okuwulira obulungi. Kikulu okugoberera ebiragiro by’omusawo, okumira eddagala mu budde, n’okukuuma enteekateeka zo.

Era kiyinza okukuwa obuweerero okutegeeza ab’omu maka go n’emikwano nti olina obulwadde bwa Long QT Syndrome. Singa ofuna obubonero nga bali naawe, basobola okukubira essimu okuyambibwa mu bwangu. N’ekisinga obulungi, singa bamanyi okukola CPR, kiyinza okutaasa obulamu bwo. Teweeraliikiriranga, bw’oddukanya obulungi, naawe osobola okubeera n’obulamu obulungi.

` Long QT Syndrome, LQTS, obulwadde bw’omutima, QT interval, okukuba kw’omutima, obutatambula bulungi, endwadde z’obuzaale