Waliwo ebyafaayo by’amaka agalina kookolo? Ka tuyige ku bulwadde bwa Lynch Syndrome

Oluusi twebuuza nti, "Nnina ebyafaayo by'amaka ga kookolo, kale nneebuuza oba nange nsinga kumufuna." Mu butuufu, ebika bya kookolo ebimu bisobola okuva ku buzaale obuyisibwa okuva ku mulembe okudda ku mulala. Okugeza, Lynch Syndrome mbeera eyongera nnyo ku bulabe bwa kookolo, naye nga teyogerwako nnyo. Kikulu nnyo okubeera nga omanyi kino. Kale ka twogere ku nsonga eno simply leero.

Mu ngeri ennyangu, Lynch Syndrome kye ki?

Lynch syndrome mbeera ya buzaale esiigibwa okuva ku muzadde okudda ku mwana, oba obuzaale . Omuntu alina embeera eno atera nnyo, oba mu bulabe bw’okufuna ebika bya kookolo ebimu okusinga ebirala.

Okusingira ddala, omuntu alina embeera eno alina emikisa mingi egy’okufuna kookolo w’olubuto n’omumwa gwa nnabaana ebitundu 40% ku 80% ng’aweza emyaka 70. Waliwo n’emikisa mingi egy’okufuna kookolo wa nnabaana, enkwaso, n’olubuto. Eky’enjawulo ku kino kiri nti kookolo asobola okukula nga bukyali nnyo okusinga emyaka gya kookolo egya bulijjo, mpozzi mu myaka gya 30 oba 40.

Kiki ekivuddeko embeera eno?

Kino okukitegeera, ka tulowooze ku mibiri gyaffe okumala akaseera. Emibiri gyaffe gikolebwa obuwumbi n’obuwumbi bw’obutoffaali. Obutoffaali buno buli kiseera buba bwawukana ne bukola obutoffaali obupya. Kilowoozeeko ng’okukola kkopi n’ekyuma ekikuba ebifaananyi. Obutoffaali bwe bwawukana mu ngeri eno, oluusi wabaawo ensobi entonotono. Naye ekirungi, DNA y’omubiri gwaffe erimu ‘obuzaale obuddaabiriza obutakwatagana’ obw’enjawulo obutegeera ensobi zino ne zizitereeza.

Omuntu alina obulwadde bwa Lynch syndrome alina ekikyamu oba ensobi mu emu ku ‘checker genes’ zino . Olwo, obutoffaali obwo bwe bwawukana, ensobi endala tezitereezebwa, era obutoffaali obulema bweyongera okweyawulamu, era obutoffaali obulala bungi obulema ne butandika okutondebwa mu mubiri. Ekiseera bwe kigenda kiyitawo, obutoffaali buno obulema bufuuka kookolo.

Singa maama wo oba taata wo alina embeera eno, naawe olina emikisa gya 50% okugisikira.

Bubonero ki obuyinza okulaga nti obulwadde bwa Lynch syndrome?

Waliwo ensonga enkulu eziwerako eziyinza okuleeta okweraliikirira ku mbeera eno. Singa ekimu oba ebisingawo ku bino bikwata ku ggwe oba ab’omu maka go, kikulu nnyo okwogera n’omusawo.

Otegeera otya embeera eno?

Singa ggwe oba omuntu mu maka go aba alina kookolo era omusawo wo n’ateebereza nti kiyinza okuba nga kiva ku bulwadde bwa Lynch syndrome, akatono aka kookolo kayinza okukeberebwa. Waliwo engeri bbiri enkulu ez’okukola kino:

• Immunohistochemistry (IHC) test: Kino kikebera ebika bya puloteyina ezisangibwa mu butoffaali bwa kookolo. Singa puloteyina ezikolebwa ‘checker genes’ ze twayogeddeko emabegako teziri mu butoffaali obwo, kiyinza okuba akabonero ka Lynch syndrome.
• Microsatellite instability (MSI) test: Kino kikebera butereevu ensobi mu DNA y’obutoffaali bwa kookolo.

Singa okukebera kuno kukakasa nti olina obulwadde bwa Lynch syndrome, oba bw’oba ​​olowooza nti oli mu bulabe olw’okuba omuntu mu maka go alina embeera eno, osobola okukeberebwa obuzaale ku musaayi okuzuula obukakafu oba naawe olina ekikyamu kino mu buzaale.

Obuwagizi okuva eri omukugu mu kubuulirira ku by’obuzaale

Mu kiseera kino, omusawo ayinza okukusindika ew’omukugu mu kubuulirira ku buzaale. Bajja kukunnyonnyola ebintu bingi ku nsonga eno.

• Engeri obulwadde bwa Lynch gye busikira mu maka.
• Ebyava mu lipoota yo ey’okukebera obuzaale kye bitegeeza.
• Engeri ebivuddemu bino gye bikosaamu obulabe bwo obwa kookolo.
• Emikisa gy’abaana bo okusikira obuzaale buno okuva gy’oli.
• Enkola zo ez’okuziyiza kookolo.

Bw’oba ​​olina obulwadde bwa Lynch syndrome, buddukanyizibwa butya?

Ekisinga obulungi ng’omanyi nti olina embeera eno kwe kugenda okwekebejjebwa buli kiseera okukebera kookolo. Olwo, ne bwe kiba nti kookolo akula, atera nnyo okuzuulibwa nga bukyali nnyo n’awona ddala . Okugeza kookolo w’olubuto olunene asobola okuwona mu bitundu 90% singa azuulibwa nga bukyali.

Omusawo ajja kusalawo okukeberebwa kw’olina okukola n’emirundi gy’olina okwetaaga. Ebigezo ebitera okusemba bye bino:

• Okukebera olubuto: Okutandika ku myaka 20-25, oyinza okusabibwa okukeberebwa kuno buli mwaka oba ebiri. Kino kikebera oba waliwo ebirungo ebiyitibwa polyps oba obubonero bwa kookolo mu kyenda ekinene.
• Endoscopies: Okutandika mu myaka gyo egy’obukulu 30, kino osobola okukikola buli luvannyuma lwa myaka 3-5 okwekenneenya olubuto n’ebyenda.
• Okukebera abakyala: Oluvannyuma lw’emyaka 30, okukebera nnabaana n’enkwaso kuyinza okuteesebwako buli mwaka okukebera nnabaana n’enkwaso.

Abantu abamu naddala abakyala abazaala abaana boogera n’omusawo waabwe ku ky’okulongoosebwa okuziyiza okukendeeza ku bulabe bwa kookolo. Kino kitegeeza okulongoosa okuggyamu ekyenda ekinene, nnabaana oba enkwaso nga kookolo tannafuna. Kino kisalawo kya muntu ku bubwe ddala.

Obukulu bw’obulamu obulungi

Wadde okwekebejjebwa buli kiseera, okubeera n’obulamu obulungi nakyo kiyamba okukendeeza ku bulabe buno.

• Lya emmere erimu enva endiirwa, ebibala, ebinyeebwa n’emmere ey’empeke.
• Kola dduyiro buli kiseera .
• Fuga obuzito bwo.
• Kkomya ku kunywa omwenge.

Okunoonyereza okumu kulaga nti okumira eddagala lya aspirin erya ddoozi entono buli lunaku kiyinza okukendeeza ku bulabe buno, naye okunoonyereza okusingawo kwetaagibwa ku kino. N’olwekyo , totandika kumira ddagala ku bubwo nga tewebuuzizza ku musawo wo.