Ebiziyiza omubiri gwo biba bitono? Ka twogere ku neutropenia!

Otera okulwala? Oba waliwo omusawo eyatunuulidde omusaayi gwo n'agamba nti, "Obutoffaali bwo obweru butono katono?" Mpozzi olina omusujja, owulira nga munafu katono, naye nga tosobola kutegeera lwaki. Mu biseera nga bino, kiyinza okuba ekikulu ennyo gy’oli okumanya embeera eno eyitibwa neutropenia, gye twogerako leero. Tofaayo, ka tukinnyonnyole mu ngeri ennyangu.

Neutropenia kye ki? Kyangu nnyo!

Mu ngeri ennyangu, obulwadde bwa neutropenia mbeera ng’omusaayi gwo gulina omuwendo omutono okusinga ogwa bulijjo ogw’ekika ky’obutoffaali obweru obuyitibwa neutrophils. Lowooza ku biwuka bino ebiyitibwa neutrophils ng’abaserikale ba poliisi abatendeke mu ngeri ey’enjawulo munda mu mibiri gyaffe. Bano be balwanyisa obuwuka, gamba nga bakitiriya ne virus, ebiyingira mu mibiri gyaffe ne bitukuuma obutakwatibwa ndwadde.

Abaserikale bano abayitibwa neutrophils basinga kukolebwa mu kkolero eriri munda mu busimu bwaffe obw’amagumba. Kale, omuwendo gwa neutrophils zino bwe gukendeera, obusobozi bw’omubiri gwaffe okulwanyisa obuwuka nabwo bukendeera. Ekyo kitegeeza nti emikisa gy’okukwatibwa yinfekisoni gyeyongera nnyo. Mu mbeera ezimu ez’amaanyi, ne bakitiriya mu budde obutuufu tezitawaanya nnyo muntu mulamu, gamba ng’ezo eziri mu kamwa oba mu byenda byaffe, zisobola okutuleetera obulwadde obw’amaanyi. Otegedde?

Omutindo gwa bulijjo ogwa neutrophils gulina okuba gutya?

Neutropenia esengekebwa okusinziira ku muwendo gwa neutrophils mu musaayi. Okutwalira awamu kikkirizibwa nti omuntu omukulu alina okuba ne neutrophils ezitakka wansi wa 1,500 buli microliter y’omusaayi. (Abamu ekkomo lino bakitwala nga 1,800). Laba engeri gye kimenyekamu:

• Okukendeera kw’obusimu obutono: Wakati wa 1,000 – 1,500 neutrophils.
• Neutropenia ey’ekigero: Wakati wa neutrophils 500 – 1,000.
• Neutropenia ey’amaanyi: Neutrophils ezitakka wansi wa 500.

Embeera eno eyinza okuba ey’akaseera obuseera (acute) oba ey’ekiseera ekiwanvu (chronic). Era kiyinza okuba nga kyazaalibwa oba nga kyafunibwa.

Ani asinga okulwala obulwadde bwa neutropenia?

Neutropenia oluusi eyinza okuva ku yinfekisoni. Wabula kisinga kulabibwa ng’ekizibu ekiva mu bujjanjabi bwa kookolo naddala obw’eddagala eriweweeza ku bulwadde bwa kookolo. Abanoonyereza bagamba nti abantu abawera 50% abafuna eddagala lya Chemotherapy bayinza okulwala obulwadde bwa neutropenia.

Waliwo ekika ekirala ekiyitibwa `Benign Ethnic Neutropenia (BEN).` Eno mbeera ya buzaale, ewangaala. Businga kubeera mu bantu abava mu Afirika, mu Buvanjuba obw’Amasekkati n’Abayindi ab’amaserengeta. Abantu bano balina omuwendo gwa neutrophil ogutakka wansi wa 1,500, naye tebali mu bulabe bwa maanyi bwa kukwatibwa yinfekisoni.

Obulwadde bwa neutropenia bukosa butya omubiri gwange?

Ebiva mu kukendeera kw’obusimu (neutropenia) byawukana okusinziira ku muwendo gw’obusimu bwo. Omuntu alina obulwadde bwa neutropenia obutono ayinza obutaba na bubonero bwonna. Kitera okuzuulibwa mu butanwa nga bakeberebwa omusaayi okuzuula embeera endala. Kyokka bw’oba ​​olina obulwadde bwa neutropenia obw’ekigero oba obw’amaanyi, oba mu bulabe bwa maanyi nnyo obw’okufuna yinfekisoni. Obulwadde bwa neutropenia obw’amaanyi buyinza okutta omuntu singa tebujjanjabwa bulungi. Eno y’ensonga lwaki kikulu okumanya embeera eno.

Lwaki obulwadde bwa neutropenia bubaawo? Biki ebivaako?

Neutropenia eyinza okuva ku nsonga ssatu enkulu:

1. Obusigo bwo obw’amagumba tebukola neutrophils zimala.

2. Okumenya (okusaanawo) okw’amangu kwa neutrophils ezikolebwa.

3. Oba, okusaanyaawo obusimu obuyitibwa neutrophils obukoleddwa.

Zino ze zimu ku nsonga lwaki:

• Embeera z’obuzaale: Oluusi embeera eno esobola okusiigibwa okuva mu bazadde okutuuka ku baana okuyita mu buzaale. Benign Ethnic Neutropenia (BEN), Cyclic neutropenia, ne Severe congenital neutropenia bye bimu ku bika ebiva ku buzaale obw’engeri eyo.
• Yinfekisoni: Neutropenia era esobola okuva ku yinfekisoni z’akawuka, bakitiriya n’obuwuka obusirikitu. Eby’okulabirako mulimu akawuka ka siriimu, ekibumba, akafuba, sepsis (obulwadde obw’amaanyi mu musaayi), n’obulwadde bwa Lyme.
• Kookolo: Kookolo nga leukemia, lymphoma, n’endwadde endala ezikwata ku musaayi oba obusigo bw’amagumba ziyinza okuleetera omubiri obutasobola kukola butoffaali buzungu bulamu bwe gwetaaga, ekivaamu okukendeera kw’obusimu obuyitibwa neutropenia.
• Eddagala: Obujjanjabi bwa kookolo, gamba ng’obujjanjabi bw’eddagala n’obusannyalazo busobola okwonoona obusimu obuyitibwa neutrophils n’obusigo bw’amagumba obubukola. Ate era, eddagala erimu eriwonya embeera endala ezitali za kookolo liyinza okukendeeza ku bungi bwa neutrophil ng’ekizibu.
• Obutaba na mmere: Obulwadde bw’obusimu obuyitibwa Neutropenia busobola okubaawo singa omubiri tegufuna vitamiini n’ebiriisa ebimala, gamba nga vitamiini B12, folate oba ekikomo.
• Obutabeera na busimu obuziyiza endwadde: Kino bwe kiba nti abaserikale baffe bennyini tebategeera bubi abaserikale baffe bennyini ne bakola obutoffaali obuziyiza endwadde obusaanyaawo obuwuka obuyitibwa neutrophils obulamu. Kiringa eggye lyaffe lye lyerumbye. Obulwadde bwa Crohn, lupus, n’endwadde z’enkizi ze zimu ku mbeera zino.

Oluusi wabaawo embeera eyitibwa `Chronic idiopathic neutropenia`. Kwe kugamba, waliwo okukendeera kw’obusimu obuyitibwa neutropenia, naye ekituufu ekivaako tekisobola kuzuulibwa .

Lwaki obujjanjabi bwa kookolo buleeta obulwadde bwa neutropenia?

Obujjanjabi bwa kookolo nga chemotherapy ddagala lya maanyi nnyo. Zitta obutoffaali bwa kookolo. Kyokka era zisobola okwonoona obutoffaali obulamu obweyawukana amangu. Neutrophils zaffe n’obutoffaali bw’obusimu bw’amagumba obuzikola nabyo butoffaali obweyawulamu mangu. Eno y’ensonga lwaki obulwadde bwa neutropenia butera okubeerawo mu kiseera ky’okujjanjaba eddagala. Emiwendo gya neutrophil gitera okusinga okukka mu wiiki bbiri ezisooka ng’ofunye obujjanjabi. Oluvannyuma lw’ekyo, ziddamu okweyongera mpolampola.

Kikulu nnyo okukola emitendera egy’enjawulo okwekuuma yinfekisoni mu kiseera kino, kuba kino kye kiseera obuziyiza bw’omubiri we businga okunafuwa.

Bubonero ki obulaga obulwadde bwa neutropenia?

Neutropenia yennyini terina bubonero bwonna bwa njawulo. Wabula singa ofuna yinfekisoni olw’obulwadde bwa neutropenia, oyinza okufuna obubonero bw’obulwadde obwo. Okukwatibwa yinfekisoni enfunda eziwera nakyo kiyinza okuba akabonero k’okukendeera kw’obusimu obuyitibwa neutropenia. Bino bye bimu ku bubonero obulaga nti obulwadde buno:

• Omusujja (naddala embeera eyitibwa febrile neutropenia) .
• Obukoowu
• Okulumwa emimiro (Pharyngitis) .
• Ennywanto z’omusaayi ezizimba
• Amabwa mu kamwa oba okwetooloola enseke
• Obulumi, okuzimba, n’okumyuuka mu kifo awakwatibwa obuwuka
• Obutagaaya mmere, ekiddukano
• Obubonero bw’omusulo, gamba ng’okwokya ng’ofulumya omusulo n’okufuka ennyo

Bw’oba ​​olina obulwadde bwa neutropenia obutono, oyinza okuba n’obusimu obumala mu mubiri gwo okulwanyisa yinfekisoni. Mu mbeera eyo, oyinza obutafuna bubonero bwonna.

Obulwadde bwa neutropenia buzuulibwa butya?

Okukebera okukulu era okwangu okuzuula kino kwe kubala omusaayi mu bujjuvu (CBC) nga kuliko enjawulo . Bw’oba ​​ojjanjabibwa nga eddagala eriweweeza ku bulwadde, omusawo wo ajja kukola okukebera kuno buli kiseera okulondoola emiwendo gy’obutoffaali obuyitibwa neutrophil.

Omusawo bw’aba teyeekakasa kiki ekikuleetera obulwadde bwa neutropenia, ayinza okulagira okwongera okukeberebwa. Ng’ekyokulabirako, oyinza okuggyibwako sampuli y’obusimu bwo obw’amagumba ne bukeberebwa mu microscope. Okukebera kuno kuyinza okuzuula oba neutrophils zikolebwa bulungi mu busimu bwo obw’amagumba, oba zisaanawo nga zimaze okukolebwa. Amawulire gano gasobola okuyamba omusawo wo okukakasa nti ozudde obulwadde buno.

Bujjanjabi ki obujjanjaba obulwadde bwa neutropenia?

Ebika ebimu eby’obulwadde bwa neutropenia biyinza obuteetaagisa bujjanjabi. Obujjanjabi obulala businziira ku kivaako emiwendo gyo egy’obusimu obuyitibwa neutrophil obutono.

Bino wammanga bisobola okukolebwa ng’obujjanjabi:

• Eddagala eritta obuwuka: Bw’oba ​​olina obulwadde bwa febrile neutropenia ng’olina omusujja, eddagala eritta obuwuka liyinza okutaasa obulamu. Emirundi mingi ojja kuweebwa ekitanda mu ddwaaliro n’oweebwa eddagala eritta obuwuka, gamba nga saline, mu misuwa. Mu kiseera kino, wagenda kukolebwa okukebera okuzuula ekivuddeko obulwadde buno.
• Corticosteroids: Bw’oba ​​olina obulwadde bwa neutropenia obuva ku mbeera y’abaserikale b’omubiri, omusawo ayinza okukuwa eddagala eriyitibwa corticosteroids. Eddagala lino likendeeza ku mirimu gy’abaserikale b’omubiri, ekisaanyaawo obuwuka bwo obuyitibwa neutrophils.
• Granulocyte colony-stimulating factor (G-CSF): Omusawo ayinza n’okukuwa eddagala erizimba obusigo bw’amagumba okufulumya obutoffaali obweru. Bw’oba ​​ofuna obujjanjabi bw’eddagala, oyinza okuweebwa empiso eno eya G-CSF.

Singa kizuulibwa nti obulwadde bwa neutropenia buva ku ddagala ly’omira, omusawo ajja kukugamba okulekera awo okumira eddagala eryo oba okukyusa eddagala.

Neutropenia esobola okuziyizibwa?

Tetusobola kuziyiza ngeri za buzaale eza neutropenia. Wabula bw’oba ​​ogenda kujjanjabwa ddagala, omusawo bw’aba ateebereza nti obusimu bwo obuyitibwa neutrophil butono, ayinza okulwawo eddagala eriddako oba okukendeeza ku ddoozi. Era bayinza okukuwa amagezi okukozesa empiso ya G-CSF okwongera okukola obutoffaali obweru.

Nnyinza ntya okwekuuma yinfekisoni singa mba n’obulwadde bwa neutropenia?

Bw’oba ​​okimanyi nti neutrophils zo ntono, waliwo emitendera mingi gy’oyinza okukola okwekuuma yinfekisoni. Bino bintu bikulu nnyo by’olina okukuuma mu birowoozo.

• Naaba mu ngalo buli kiseera ne ssabbuuni oba kozesa eddagala erirongoosa mu ngalo eririmu omwenge.
• Omuli ssennyiga ne Covid-19 `(COVID-19)`Funa okugema kwo kwonna mu budde.
• Weewale abantu abalwadde n’ebifo omujjudde abantu w’oyinza okusanga omuntu omulwadde.
• Weegendereze okukunya, okusala, n’ebiwundu (omuli ttatu n’okufumita omubiri). Laba olususu lwonna olukosebwa mu bwangu.
• Okunaaba obulungi ebibala n’enva endiirwa, okwawula ennyama n’ebyennyanja ku mmere endala, era otegeke emmere mu ffumbiro eriyonjo, ng’ogifumba bulungi. Mu ngeri eno, osobola okuziyiza obuwuka okusaasaana.
• Togabana bikozesebwa mu kulya, ebikopo, oba emmere n’ebyokunywa n’abalala.
• Togabana bintu nga obutambaala, enviiri, ne bbulawuzi z’amannyo n’abalala.
• Bw’oba ​​okolera mu lusuku, yambala ggalavu.
• Weewale okuggyawo kasasiro w’ebisolo by’omu nnyumba n’okukyusa obuwale bw’abalongo nga bwe kisoboka (bw’oba ​​olina okukikola, yambala ggalavu era onaaba bulungi mu ngalo ng’omaze okumaliriza).
• Weewale okukozesa ennyanja, ebidiba, emigga, n’amazzi agookya.
• Eddagala likozese ddala nga omusawo bw’akulagidde okuziyiza yinfekisoni.

Bingi ku magezi gano bye bintu bye tutera okukola okusobola okusigala nga tuli balamu bulungi. Kyokka bw’oba ​​olina obulwadde bwa neutropenia, olina okwegendereza ennyo. Buuza omusawo kiki ekirala ky’oyinza okukola okwekuuma yinfekisoni, okusinziira ku bulamu bwo n’embeera y’obulamu bwo.

Prognosis ki eri abantu abalina neutropenia? (Okuteebereza)

Neutropenia esobola okujjanjabibwa, n’olwekyo endowooza y’abantu abasinga nnungi. Ekisinga obukulu kwe kuziyiza yinfekisoni n’okunoonya obujjanjabi mu bwangu (bw’oba ​​olwala).

Ddi lwe nnina okulaba omusawo?

Bw’oba ​​ofuna obujjanjabi bw’eddagala oba ng’olina embeera endala eyinza okuvaako obulwadde bw’obusimu obuyitibwa neutropenia, laba omusawo mu bwangu singa ofuna obubonero buno bwonna, oba kuba essimu mangu omusawo akuwe amagezi ku ky’olina okukola:

• Omusujja gwa diguli 100.4 (diguli 38 Celsius) oba okusingawo.
• Okutuuyana oba okukankana olw’ennyonta.
• Okukaluubirirwa okussa.
• Okuzibikira ennyindo.
• Okulumwa emimiro oba ensingo okukaluba.
• Okusesema okupya oba okweyongera kw’okusesema okuliwo.
• Ekiddukano ne/oba okusiiyibwa.
• Okuvaamu amazzi mu bukyala oba okusiiwa.
• Obulumi, okumyuuka oba okuzimba wonna ku mubiri.
• Enkyukakyuka mu kufulumya omusulo (obulumi, okwokya, obwetaavu bw’okufulumya omusulo ennyo).
• Obulumi obupya naddala mu lubuto oba mu nseke.
• Okuwulira nga osobeddwa oba nga wa njawulo mu birowoozo okusinga bulijjo.
• Okuwulira ng’okooye ekisusse oba nga tolina bulungi.

Engeri gy’ofunamu obulwadde bwa neutropenia esinziira ku kiki ekyaviirako emiwendo gyo egy’obusimu okukka. Singa emiwendo gyo giba wansi olw’obulwadde bw’ofuna gye buvuddeko, kirabika gijja kudda mu mbeera eya bulijjo ng’omubiri gwo guwona. Singa obulwadde bwo obw’obusimu buva ku bulwadde obw’ekiseera ekiwanvu oba eddagala eriweweeza ku bulwadde, omusawo ajja kulondoola emiwendo gy’obusimu bwo buli kiseera okutangira ebizibu ebiva mu yinfekisoni. Buuza omusawo wo oba neutropenia yo yeetaaga okukeberebwa buli kiseera mu by’obujjanjabi n’eddagala okuziyiza yinfekisoni.

N’ekisembayo, ebintu by’olina okujjukira (Obubaka bw’okutwala awaka) .

Neutropenia mbeera ng’obutoffaali obweru obw’omubiri obuyitibwa neutrophils buba butono. Kino kyongera obulabe bw’okukwatibwa obulwadde. Embeera eno esinga kubeera mu bantu abajjanjabwa kookolo ng’eddagala eriweweeza ku bulwadde bwa kookolo.

Si kyeraliikiriza, waliwo obujjanjabi ku kino. Ekisinga obukulu kiri nti:

• Goberera ddala ebiragiro by’omusawo wo.
• Okukola buli kimu ekisoboka okwekuuma obutakwatibwa yinfekisoni.
• Bw’olaba obubonero bwonna obulaga nti olina obulwadde, gamba ng’omusujja , genda mangu omusawo amagezi.

Kino bw’oba ​​okimanyi era n’okwegendereza, osobola okusigala ng’oli mulamu bulungi ne bw’oba ​​n’obulwadde bwa neutropenia. Tolonzalonza kwogera na musawo wo ku bibuuzo byonna oba ebikweraliikiriza by’oyinza okuba nabyo.

` Neutropenia, neutrophils, obutoffaali obweru, obutafaali obuziyiza endwadde, yinfekisoni, kookolo, eddagala