Obusimu bwo bwonna obw’omu lubuto (pituitary hormones) butono? Ka twogere ku bulwadde bwa panhypopituitarism!

Oluusi ebintu mu mibiri gyaffe tebikola nga bwe kisuubirwa, nedda? Obusimu kibinja ky’ababaka abakulu ennyo abeenyigira kumpi mu buli nkola mu mubiri gwaffe. Singa wabaawo ekizibu mu nkola eno ey’obusimu, kiyinza okukosa obulamu bwaffe bwonna. Leero tugenda kwogera ku mbeera etali ya bulijjo buli muntu gy’alina okukimanya. Ekyo kye kizibu kya panhypopituitarism.

Obulwadde bwa Panhypopituitarism kye ki?

Mu ngeri ennyangu, obulwadde bwa panhypopituitarism mbeera etali ya bulijjo ng’endwadde ya pituitary gland, akatundu akatono mu bwongo bwaffe, tekola kimala oba nga temuli busimu bwonna bwe bukola. Ekitundu kya "pan" kitegeeza "bonna." Embeera eno esobola okukwata abalongo, abaana n’abantu abakulu.

Kati osanga weebuuza nti, "Obusimu buno bwe buruwa? Lwaki bukulu nnyo?" Okay, ka tulabe ekyo.

Obusimu bulinga ababaka mu mibiri gyaffe. Zino ddagala lya njawulo. Zitambula mu musaayi gwaffe ne zitwala obubaka mu bitundu by’omubiri eby’enjawulo, ebinywa n’ebitundu ebirala. Zikwasaganya, kwe kugamba, zifuga era zikwasaganya ebikolwa eby'enjawulo eby'omubiri gwaffe, nga zibagamba nti "kikola kino, kikole mu kiseera kino, kikole bwe kiti."

Ensigo yaffe ey’omu lubuto (pituitary gland) eringa entangawuuzi. Kisangibwa ku musingi gw’obwongo bwaffe, wansi ddala w’ekitundu ekiyitibwa hypothalamus. (Hypothalamus kifo kinene mu bwongo ekifuga ebintu bingi ebikulu, omuli n’obusimu bwaffe obw’okwefuga.) Wadde nga ntono, enseke z’omubiri (pituitary gland) zikola kinene nnyo mu nkola yaffe ey’omubiri (endocrine system). Kwe kugamba, obusimu buno obuyitibwa pituitary hormones bwe bufuga ebintu bingi mu mubiri gwaffe, gamba ng’enkyukakyuka y’omubiri, okukula n’okuzaala.

Mu budde obwabulijjo, emibiri gyaffe gitereeza n’obwegendereza obusimu buno. Kyokka singa ekimu ku busimu buno kifuuka ekitono ennyo, kiyinza okuleeta obubonero obw’enjawulo n’obuzibu mu bulamu. Panhypopituitarism bwe busimu bwonna obukolebwa enseke z’omubiri (pituitary gland) bwe buba obutono ennyo, ekivaako obubonero obw’enjawulo.

Njawulo ki eriwo wakati w’obulwadde bwa Panhypopituitarism ne Hypopituitarism?

Amannya gano gombi gafaanagana katono, n’olwekyo gayinza okubutabula. Lowooza ku kino, obulwadde bwa hypopituitarism mbeera nga hormone emu oba eziwera zikolebwa enseke y’omubiri. Panhypopituitarism nsonga ya njawulo, esinga okukwata ku nsonga y’emu. Kwe kugamba, obulwadde bwa panhypopituitarism buba bbula mu busimu bwonna obukolebwa enseke z’omubiri (pituitary gland). Ekigambo "pan" kitegeeza "bonna", kale kinnyonnyola embeera eno.

Busimu ki obukolebwa enseke z’omubiri (pituitary gland)?

Waliwo ebika by’obusimu ebiwerako ebikolebwa era ne bifulumizibwa (ebifulumizibwa) endwadde yaffe eya pituitary gland. Buli emu ku zo erina omulimu ogw’enjawulo. Ka tulabe kiki kye bali:

• Obusimu obuyitibwa Adrenocorticotropic hormone (ACTH oba corticotropin): Buno busitula endwadde zaffe ez’omu kibumba okukola obusimu obuyitibwa cortisol. Cortisol eno era eyitibwa ‘obusimu bwa situleesi’. Kikulu nnyo mu kufuga puleesa ne glucose mu musaayi.
• Follicle-stimulating hormone (FSH): Obusimu buno buyamba okusitula ensigo mu basajja n’okusitula enkwaso mu bakyala okukola obusimu obuyitibwa estrogen n’okukuza amagi.
• Growth hormone (GH): Nga erinnya bwe liraga, kyetaagisa nnyo mu kukula kw’abaana. Era kiyamba okukuuma ebinywa n’amagumba nga biramu mu bantu abakulu, era kikosa ensaasaanya y’amasavu mu mubiri. GH nayo yeenyigira mu nkyukakyuka yaffe mu mubiri.
• Luteinizing hormone (LH): LH yeetaagibwa okusitula okufulumya eggi mu bakyala n’okusitula okukola ekirungo kya testosterone mu basajja.
• Prolactin: Obusimu buno buyamba okukola amata g’amabeere ng’omwana amaze okuzaalibwa. Era kiyinza okukosa enkola y’okugenda mu nsonga mu bakyala n’okuzaala n’enkola y’okwegatta mu bantu abakulu.
• Obusimu obusitula thyroid (TSH): Buno busitula endwadde yaffe eya thyroid okukola obusimu bwa thyroid, obuddukanya enkyukakyuka mu mubiri, amaanyi n’obusimu.

Ng’oggyeeko bino, enseke y’omubiri (pituitary gland) etereka era n’efulumya obusimu obulala bubiri bwe kiba kyetaagisa. Kyokka bino bikolebwa ekiwuka ekiyitibwa hypothalamus:

• Antidiuretic hormone (ADH oba vasopressin): Hormone eno etereeza obungi bw’amazzi ne sodium (omunnyo) mu mubiri gwaffe.
• Oxytocin: Ayamba abakyala okukonziba nnabaana nga bazaala, era ayamba n’amata g’amabeere okutambula. Obusimu buno era kigambibwa nti bukosa enkolagana wakati w’abazadde n’abalongo.

Laba, nga omulimu mukulu nnyo akatundu kano akatono aka pituitary gland kakola! Kale, okukendeera kw’obusimu buno bwonna kuyinza okuba n’akakwate akanene.

Ani asinga okukosebwa embeera eno ey’obulwadde bwa panhypopituitarism?

Mu butuufu, embeera eno eyitibwa panhypopituitarism esobola okubaawo mu muntu yenna, ku myaka gyonna. Tewali kkomo lya myaka oba kitundu kitongole.

Embeera eno ya bulijjo etya?

Eno mbeera ya bbula nnyo . Mu nsi yonna, obulwadde buno butegeezebwa mu bantu bana bokka ku buli lukumi buli mwaka. N’olwekyo, kya bulijjo obutawulira bingi ku nsonga eyo.

Obulwadde bwa Panhypopituitarism buyinza okuba obw’obulabe eri obulamu?

Yee, mu mbeera ezimu embeera eno eyinza okutta omuntu. Naddala singa obusimu obuyitibwa adrenocorticotropic hormone (ACTH) buba butono nnyo, kiyinza okuba eky’obulabe.

Ensonga lwaki kino kiri bwe kityo eri nti obutaba na ACTH kiyinza okuvaako embeera ey'amangu eyitibwa adrenal crisis . Kino era kiyitibwa ``acute cortisol insufficiency''. ACTH y’efuga emiwendo gyaffe egya cortisol. Kale ACTH bw’eba eweddewo, cortisol takolebwa. Obuzibu buno obw’ekibumba (adrenal crisis) mbeera eyeetaaga okujjanjabibwa amangu era eyinza n’okuteeka obulamu mu matigga.

Obubonero bw’obuzibu bw’ekibumba buyinza okuli:

• Omusujja
• Obunafu obw’amaanyi
• Okutabulwa (obutategeerekeka) .
• Puleesa ekka (hypotension) .
• Omutima okukuba amangu (tachycardia) .
• Okusesema
• Embiro
• Ssukaali omutono mu musaayi (hypoglycemia) .

Ggwe oba omwana wo bw’oba ​​n’obubonero buno bwonna, genda mu ddwaaliro erikuli okumpi mu bwangu oba kuba 1990. Kino kya mangu!

Bubonero ki obulaga obulwadde bwa Panhypopituitarism?

Obubonero bw’obulwadde buno buyinza okwawukana ennyo okusinziira ku muntu, okusinziira ku bungi bwa buli busimu bwa pituitary obubulamu n’engeri embeera gy’egenda mu maaso amangu oba mpola.

Wano waliwo obubonero obutera okulabika mu baana n’abantu abakulu:

• Okuziyira oba okuziyira
• Obukoowu obuyitiridde
• Okwennyamira ne/oba okweraliikirira
• Okukwatibwa yinfekisoni enfunda eziwera
• Ssukaali omutono mu musaayi (hypoglycemia) .
• Obutasobola kugumira nnyonta
• Olususu olukalu mu ngeri etaali ya bulijjo
• Okugejja oba okweyongera awatali nsonga
• Ebipimo by’amasavu ne kolesterol mu musaayi ebitali bituufu (dyslipidemia) .
• Omutima okukuba amangu (tachycardia) .
• Ennyonta esusse n’okufuka ennyo
• Okugenda mu nsonga ezitali za bulijjo mu bakyala
• Obutazaala bw’abakyala
• Obutazaala bw’abasajja

Waliwo obubonero obulala obukwata ennyo abalongo, abawere, ne/oba abaana abato:

• Jaundice okumala ebbanga eddene mu balongo
• Obusajja obutono mu balongo abasajja (micropenis) .
• Okukula okulemererwa (obutakula buwanvu) .
• Okulwawo okutuuka mu myaka gy’obuvubuka

Olw’okuba obubonero buno buyinza okufaananako n’embeera endala ez’obujjanjabi, kikulu okuzuulibwa obulungi singa oba olina obubonero obupya oba obutasalako nga buno. N’olwekyo, laba omusawo akuwe amagezi.

Biki ebivaako obulwadde bwa panhypopituitarism?

Waliwo ebintu ebiwerako ebiyinza okuvaako embeera eno. Oluusi abasawo tebasobola kuzuula nsonga ntongole. Kino kiyitibwa obulwadde bwa idiopathic panhypopituitarism.

Okutwalira awamu, ensonga enkulu lwaki kino kikoleddwa eri nti hypothalamus ne/oba pituitary gland yaffe eyonoonese mu ngeri emu oba endala, ekivaako emu oba zombi obutakola bulungi.

Okusobola okutegeera ensonga zino, olina okuba n’okutegeera okutono ku ngeri hypothalamus yaffe ne pituitary gland gye bikolaganamu.

Enkolagana ya Hypothalamus-pituitary gland

Lowooza ku hypothalamus yaffe, pituitary gland, ne pituitary gland nga CEO era maneja wa kampuni ennene. Ebibiri bino byonna awamu bikola ng’ekifo ekikulu ekifuga obwongo bwaffe (hypothalamus-pituitary complex), nga bifuga enkola enkulu ennyo mu mubiri.

Hypothalamus kye kitundu ky’obwongo bwaffe ekivunaanyizibwa ku mirimu gy’omubiri egiwerako emikulu. Kiweereza obubaka eri obusimu bwaffe obw’okwefuga. Era egamba enseke z'omubiri (pituitary gland) "okukola obusimu buno, bufulumya buno." Obusimu buno obuyitibwa pituitary hormones bukosa ebitundu by’omubiri ebirala.

Ensigo y’omubiri (pituitary gland) eyungibwa ku hypothalamus n’ekikolo ekirimu emisuwa n’obusimu obuyitibwa ``pituitary stalk.'' Okuyita mu kikolo kino hypothalamus mw’ewuliziganya n’enkwaso.

Hypothalamus ekola obusimu obuwerako okusitula endwadde ya pituitary:

• Obusimu obufulumya eddagala lya corticotropin
• Ekirungo kya Dopamine
• Obusimu obufulumya Gonadotropin
• Obusimu obufulumya obusimu bw’okukula
• Eddagala lya Somatostatin
• Obusimu obufulumya thyrotropin

Olw’okuba enseke z’omubiri (pituitary gland) ne hypothalamus zikolagana nnyo, okwonooneka kw’ekimu kuyinza okukosa enkola y’obusimu bwa munne. Eno y’ensonga enkulu ey’okukula kw’obulwadde bwa panhypopituitarism.

Ebivaako ebikwata ku nseke z’omubiri (pituitary gland).

Embeera eziyinza okwonoona enseke z’omubiri (pituitary gland) n’okuleeta obulwadde bwa panhypopituitarism mulimu:

• Pituitary adenomas (bino bizimba ebitali bya kookolo) .
• Okulongoosa enseke z’omu lubuto (emirundi mingi okuggyawo endwadde zino eziyitibwa adenomas) .
• Obujjanjabi bw’amasannyalaze (radiation therapy) ku bulwadde bwa pituitary adenoma
• Pituitary apoplexy (okusaanawo okw’amangu kw’ebitundu by’omubiri ebiyitibwa pituitary tissue olw’okukendeera kw’omusaayi mu nseke oba okuvaamu omusaayi) .
• Ensigo y’omubiri (pituitary gland) tekula bulungi oba ekolebwa mu ngeri etaali ya bulijjo ng’azaalibwa.

Ebivaako ebikwata ku hypothalamus

Embeera eziyinza okwonoona hypothalamus n’okuleeta obulwadde bwa panhypopituitarism mulimu:

• Obuvune ku bwongo obuva ku buvune (TBI) .
• Okulongoosa obwongo nga kukolebwa ku hypothalamus oba okumpi nayo
• Ebizimba ebitali bya kookolo ebikula mu hypothalamus (e.g. craniopharyngiomas) .
• Kookolo eyasaasaana (metastasized) okutuuka mu hypothalamus okuva awalala mu mubiri (e.g. amawuggwe, kookolo w’amabeere) .
• Hydrocephalus (puleesa eva ku mazzi okukuŋŋaanyizibwa mu bwongo) .
• Storoko
• Obulwadde bw’akafuba obuyitibwa meningitis

Obulwadde bwa Panhypopituitarism buzuulibwa butya?

Bw’oba ​​olina obubonero bw’obulwadde buno, omusawo ajja kusooka kukubuuza ku bubonero bwo n’ebyafaayo by’obujjanjabi, n’oluvannyuma akukebere omubiri.

Olwo, okukeberebwa okwetaagisa kulagirwa okukakasa embeera y’obulwadde bwa panhypopituitarism n’okugaana embeera endala eziyinza okuba nga ze zireeta obubonero buno.

Biki ebikebera okuzuula obulwadde?

Abasawo batera okukola ebigezo ebiwerako okuzuula obulwadde buno omuli okukebera ebifaananyi n’okukebera obusimu.

Ebigezo by’okukuba ebifaananyi

Panhypopituitarism eva ku kwonooneka kwa hypothalamus oba pituitary gland, era okukebera ebifaananyi nga kuno kuyinza okukolebwa okuzuula ekivaako:

• Brain MRI (Magnetic Resonance Imaging) scan: MRI scan ekozesa amayengo ga leediyo n’amaanyi ga magineeti okufulumya ebifaananyi ebikwata ku munda mu mubiri. MRI scans zitwalibwa ng’engeri esinga okuzuula ebizimba by’omubiri (pituitary tumors). Era zisobola okuyamba okuzuula ebizibu ebirala ebiri ku hypothalamus oba pituitary gland.
• CT (Computed Tomography) scan of the brain: CT scan ekozesa X-ray ne kompyuta okukola ebifaananyi ebikwata ku bwongo mu bujjuvu. Okukebera kuno kuyinza okukozesebwa okukebera oba waliwo ekizimba ku bwongo oba pituitary adenoma. Era kiyinza okuyamba okuzuula ebizibu ebirala ebiri ku hypothalamus oba pituitary gland.

Okukebera obusimu

Bw’oba ​​olina obubonero bw’obulwadde bwa panhypopituitarism, omusawo wo ajja kwetaaga okupima emiwendo gya buli busimu obufulumizibwa enseke z’omubiri. Kino kijja kuyamba okuzuula buli busimu bw’eri wansi n’okugaana embeera endala.

Wadde ng’obusimu obumu obwa pituitary mu budde obutuufu bubeera mu musaayi gwaffe ku mutindo ogutakyukakyuka, obusimu obulala bukyukakyuka nnyo olunaku lwonna. N’olwekyo, okukebera obusimu obumu kuyinza okukolebwa ng’okukebera omusaayi okwangu, ate okulala kwetaaga okukeberebwa okw’enjawulo okw’okusikirizibwa.

Okukebera omutindo gw’obusimu mulimu:

• Okukebera omusaayi: Okukebera omusaayi okwangu kusobola okupima obusimu obuyitibwa pituitary hormone nga thyroid-stimulating hormone (TSH), prolactin, follicle-stimulating hormone (FSH), ne luteinizing hormone (LH). Era zisobola okupima obusimu obulala obukosebwa obusimu obuyitibwa pituitary hormones, gamba nga thyroxine, estrogen, ne testosterone.
• Okugezesebwa kw’okusikirizibwa kwa ACTH:Kino kikebera engeri endwadde zo ez’omu kibumba gye zikwatamu obusimu obuyitibwa adrenocorticotropic hormone (ACTH). Kino kizingiramu okukuwa empiso ya ACTH ey’obutonde n’okutwala omusaayi buli luvannyuma lwa kiseera.
• Okukebera obusimu bw’okukula (GH) stimulation test: Ku kukebera kuno, omusawo ajja kukukuba empiso y’eddagala. Eddagala lino litera okusitula enseke okufulumya obusimu obukula. Olwo, omusaayi gwo gujja kuggyibwako era GH levels zo zijja kupimibwa.
• Okukebera okugumira insulini: Okukebera kuno kuyamba okuzuula obusimu obukula (GH) n’obutaba na ACTH.

Obulwadde bwa Panhypopituitarism bujjanjabwa butya?

Obujjanjabi bw’embeera eno bwawukana okusinziira ku muntu. Kisinziira ku busimu bw’omubiri obuyitibwa pituitary hormone bwe buli wansi ne kiki ekivaako obuzibu. N’olwekyo, enteekateeka y’obujjanjabi ya muntu ku bubwe nnyo. Ttiimu yo ey’abasawo ejja kukusalawo enteekateeka y’obujjanjabi esinga obulungi gy’oli.

Ebimu ku bikozesebwa mu bujjanjabi bye bino:

• Obujjanjabi obukyusa obusimu: Ekigendererwa kya kino kwe kuzzaawo obusimu bw’omubiri (pituitary hormones) obubadde buweddewo okutuuka ku mutindo omulamu. Abantu abalina obulwadde bwa panhypopituitarism bajja kwetaaga obujjanjabi obw’okukyusa obusimu obulamu bwabwe bwonna okuggyako ng’ekizibu ekivaako ekizibu kino kisobola okujjanjabibwa. Eddagala erimu erikyusa obusimu limira ng’empeke, ate eddala liweebwa ng’empiso.
• Okulongoosa: Singa embeera eno eva ku kizimba ku bwongo oba ekizimba ekiyitibwa pituitary adenoma, omusawo ayinza okukuwa amagezi okulongoosebwa okuggyamu ekizimba.
• Obujjanjabi bw’amasannyalaze: Singa embeera eno eva ku kizimba ku bwongo oba ekizimba ekiyitibwa pituitary adenoma, obujjanjabi bw’amasannyalaze buyinza okulagirwa okujjanjaba oba okukendeeza ku kizimba.
• Corticosteroids: Oyinza okwetaaga okumira dose nnyingi eza corticosteroids nga tonnaba na/oba mu kiseera ky’ekintu kyonna ekireeta situleesi mu mubiri oba mu birowoozo. Ebintu ebinyigirizibwa mu mubiri mulimu okulwala, okukwatibwa yinfekisoni, n’okulongoosebwa. Eddagala lino erya corticosteroids liweebwa okudda mu kifo ky’obusimu bw’omu kibumba obutakolebwa olw’obutaba na ACTH. Obusimu buno bwetaagisa nnyo ng’omubiri guli ku situleesi.

Obulwadde bwa Panhypopituitarism busobola okuwona ddala?

Mu mbeera ezimu, obulwadde bwa panhypopituitarism busobola okukyusibwa nga tujjanjaba ekivaako ekizibu (okugeza, okulongoosa okuggyawo ekizimba ky’omubiri ekiyitibwa pituitary adenoma ekyali kinyigiriza ku nseke, singa endwadde teyonoonese). Naye, mu mbeera ezisinga obungi , obutaba na busimu obuva ku panhypopituitarism kyetaagisa okujjanjabibwa obulamu bwonna.

Embeera eno esobola okuziyizibwa?

Emirundi egisinga, tewali ngeri yonna gye tuyinza kuziyiza panhypopituitarism. Wabula bw’oba ​​oli mu bulabe bw’okulwala embeera eno, waliwo engeri gy’oyinza okugizuula nga bukyali.

Bw’oba ​​ofunye ekimu ku bino wammanga, oba mu bulabe obw’okulwala obulwadde bwa panhypopituitarism:

• Bw’oba ​​olongooseddwa ku bwongo oba ku nseke z’omubiri (pituitary gland).
• Bw’oba ​​obadde n’obujjanjabi bw’amasannyalaze (radiation treatment) ku bwongo ne/oba enseke z’omubiri (pituitary gland).
• Singa obwongo buba bufunye ensisi olw’akabenje (Traumatic brain injury).
• Bw’oba ​​olina obulwadde bwa hydrocephalus (amazzi agakuŋŋaanyizibwa ku bwongo).

Bw’oba ​​oli mu bulabe, omusawo wo ajja kutera okukuwa amagezi okukebera enkola n’obulamu bw’endwadde yo eya pituitary gland ne/oba hypothalamus.

Kiki ekitegeeza obulwadde bwa panhypopituitarism?

Endowooza y’obulwadde buno, kwe kugamba, engeri omulwadde gy’anaayitamu mu biseera eby’omu maaso, esinziira ku bintu ebiwerako:

• Buli busimu bwa pituitary bwe buba butono.
• Emyaka gyo obulwadde bwe bwatandika.
• Embeera eno ejja kukulaakulana mpola oba mangu?
• Obulwadde buno busobola kuzuulibwa mangu ki ne butandikibwawo obujjanjabi?

Panhypopituitarism ezuuliddwa nti ekwatagana n’okukendeeza ennyo ku mutindo gw’obulamu n’obulamu obusuubirwa.

Abantu abalina embeera eno batera okuba n’emikisa egy’okugejja, okukendeeza ku buzito bw’omubiri omugonvu, n’endwadde z’emisuwa. Era bayinza okuba n’obulabe obw’okwongera okulwala obulwadde bw’amagumba (okugonza amagumba) n’okumenya amagumba.

Kyokka, obujjanjabi obw’obwegendereza, obujjuvu obw’okukyusa obusimu n’okulondoola ennyo ensonga eziyinza okuvaako emisuwa gy’omutima kiyinza okulongoosa ebivaamu. N’olwekyo, kikulu nnyo okugoberera amagezi g’abasawo.

Ddi lw’osaanidde okulaba omusawo bw’oba ​​olina obulwadde bwa panhypopituitarism?

Bw’oba ​​olina obubonero bw’obulwadde bwa panhypopituitarism, oba ng’ozuuliddwa ng’olina obulwadde buno, kirabika ojja kwetaaga okulaba omusawo w’endwadde z’omu lubuto, omusawo mukugu mu kujjanjaba obuzibu obuva ku busimu.

Ojja kwetaaga okulaba omusawo w’endwadde z’omu lubuto buli kiseera obulamu bwo bwonna okukakasa nti obujjanjabi bwo obw’okukyusa obusimu bukola bulungi n’okwewala okukyusa obusimu obususse.

Kya bulijjo okuwulira ng’otya ng’ozuuliddwa ekipya. Naye totya kubuuza musawo wo bibuuzo ku panhypopituitarism. Okuva bwe kiri nti kitera okwetaagisa okujjanjabibwa obulamu bwo bwonna n’okulondoola obusimu, kikulu okulaba omusawo buli kiseera. Bw’ofuna obubonero obupya oba obweraliikiriza, tegeeza omusawo wo amangu ago. Baliwo okukuyamba.

Ebintu ebikulu by'olina okujjukira (Take-Home Message)

Okay, kale ka tufunze ebimu ku bintu by'olina okujjukira okuva mu bye twogeddeko:

• Panhypopituitarism mbeera etatera kulabika naye nga ya maanyi nnyo ng’obusimu bwonna obukolebwa enseke z’omubiri (pituitary gland) bukendeera.
• Kino kiyinza okubaawo ensonga nnyingi, okusinga okwonooneka kw’endwadde ya pituitary gland oba hypothalamus.
• Obubonero bwawukana, era oluusi n’embeera eziyinza okutta omuntu ng’obuzibu bw’ekibumba (adrenal crisis) ziyinza okubaawo. N’olwekyo, genda mangu omusawo amagezi bw’oba ​​olina obubonero.
• Ebintu ng’okukeberebwa omusaayi ne MRI/CT scans byetaagibwa okusobola okuzuula obulungi obulwadde.
• Obujjanjabi butera okuzingiramu obujjanjabi obw’okukyusa obusimu obulamu bwonna.
• Bw’okolagana obulungi n’omusawo wo n’ofuna okukeberebwa n’obujjanjabi obutuufu, osobola okubeera obulungi n’embeera eno.

Nsuubira nti amawulire gano gakuyamba. Jjukira nti toli wekka, era abasawo n’abakola ku by’obulamu baliwo okukuyamba.

` Panhypopituitarism, pituitary gland, obutaba na busimu, hypothalamus, obujjanjabi bw’obusimu, ebizimba ku bwongo, ACTH