Omuwendo gwa platelet zo guli waggulu? Ka twogere ku bulwadde bwa Thrombocytosis!

Wali okwata lipoota yo eya Full Blood Count n’otunuulira ebintu by’eyogera? Oteekwa okuba nga olabye nti waliwo omuwendo oguyitibwa "Platelets" mu bintu ebiriyo. Oluusi omusawo agamba nti, "Omuwendo gwo ogwa platelet guli waggulu katono." Mu kiseera ekyo, kya bulijjo okuwulira ng’otya katono n’okweraliikirira. "Kino kye ki? Kiba kya maanyi?" Ggwe olowooza. Kale leero, ka twogere mu ngeri ennyangu ennyo era ey’omukwano ku kweyongera kuno okw’obutoffaali obukola omusaayi, embeera eyitibwa Thrombocytosis mu nsonga z’obusawo.

Ka tusooke tulabe, platelets kye ki?

Mu ngeri ennyangu, obutoffaali obuyitibwa platelets kika kya butoffaali butono mu musaayi gwaffe. Balowoozeeko ng’akatono aka ‘helper group’ akajja okukomya omusaayi ng’ofunye okusala oba okusenya awalala ku mubiri gwo. Zijja mangu mu kifo awaali obuvune, ne zikwatagana, ne zikola ekizimba, nga pulasita, okusiba ekiwundu. Eno y’engeri omusaayi gye gukoma. Kale osobola okulaba nti platelets kitundu kya mubiri gwaffe ekiteetaagisa era kikulu nnyo.

Naye, okufaananako ekintu kyonna, ebizibu bisobola okubaawo ng’obutoffaali buno bufuuse bungi nnyo. Thrombocytosis ye omuwendo gwa platelets mu musaayi bwe gweyongera okusinga ku mutindo ogwa bulijjo. Platelets bwe zeeyongera mu ngeri eno, omusaayi gwaffe oluusi guyinza okusiba. Kino kiyinza okuvaako ebizimba by’omusaayi ebiteetaagibwa okutondebwa mu bifo awatali buvune, kwe kugamba, munda mu misuwa. Singa ebizimba bino tebijjanjabwa, biyinza n’okuleetawo embeera ez’amaanyi ng’okulwala omutima oba okusannyalala.

Waliwo ebika bibiri ebikulu eby’obulwadde bwa thrombocytosis:

Okusinziira ku kivaako omuwendo gw’obutoffaali obuyitibwa platelets obungi mu musaayi gwo, embeera eno esobola okwawulwamu ebika bibiri ebikulu. Kikulu okutegeera bino ebibiri, kubanga enkola z’obujjanjabi zijja kusinziira ku kika kino.

Kyokka singa omusaayi gwo gulaga nti obutoffaali bw’omusaayi (platelets) bungi, kitegeeza nti waliwo ekigenda mu maaso munda mu mubiri gwo ekyetaaga okunoonyezebwa omusawo. Okusinziira ku kivuddeko ekizuuliddwa, oyinza okwetaaga obujjanjabi obw’ekiseera ekiwanvu, obujjanjabi obw’ekiseera ekitono oba obutafuna bujjanjabi n’akatono.

Bubonero ki obulaga nti obutoffaali obukola omusaayi (platelet) bungi?

Mu butuufu, abantu bangi tebafuna bubonero bwonna bulaga nti obutoffaali bungi. Kizuulibwa mu butanwa nga bakebereddwa omusaayi olw’ensonga endala.

Bw’oba ​​olina obulwadde bwa Reactive Thrombocytosis, oyinza okufuna obubonero bw’embeera eno (okugeza, omusujja oguva mu yinfekisoni).

Naye singa okweyongera kw’obutoffaali obukola omusaayi (platelets) kuleeta okuzimba omusaayi oba (nga si bulijjo nnyo) okuvaamu omusaayi munda, obubonero obumu buyinza okulabika. Embeera eno esinga kulabibwa mu bulwadde bwa Essential Thrombocytosis.

• Obukoowu
• Okuvaamu omusaayi mu nnyindo emirundi mingi
• Okuvaamu omusaayi (okunyiga) ne bwe wabaawo obuvune obutono
• Okuvaamu omusaayi okwangu okuva mu nnyindo oba mu bitundu ebirala munda mu kamwa
• Okuziyira , okulaba obubi, n’okulumwa omutwe
• Obulumi, okuzimba, n’okumyuuka mu ngalo n’ebigere (akabonero k’embeera eyitibwa erythromelalgia) .
• Obulumi mu lubuto naddala ku ludda olwa waggulu olwa ddyo olw’olubuto (kayinza okuba akabonero k’embeera nga Budd-Chiari syndrome) .

Lwaki platelets zeeyongera bwe ziti? Ensonga ze ziruwa?

Ensonga nazo zaawukana okusinziira ku bika ebibiri bye twayogeddeko emabegako.

Ebivaako obulwadde bwa Essential Thrombocytosis (ET) .

Kino kiva ku nkyukakyuka mu buzaale. Naye kino si kintu ekizaalibwa nakyo, wabula ekintu ekikulaakulana okumala ekiseera. Mu ngeri ennyangu, waliwo enkyukakyuka mu buzaale obugamba omubiri gwaffe okukola obutoffaali obuyitibwa platelets. N’ekyavaamu, obusigo bw’amagumba butandika okukola obusimu obuyitibwa platelets bungi nnyo nga tebufugibwa.

Ebivaako obulwadde bwa Reactive Thrombocytosis

Kino kyokka omubiri gwe guddamu ekizibu ekirala. Bino bye bimu ku bitera okuvaako obutoffaali obuyitibwa platelets obungi:

• Okuvaamu omusaayi: Bwe wabaawo okufiirwa omusaayi mungi olw’akabenje oba okulongoosebwa.
• Embeera za kookolo: Olw’ebika bya kookolo ebimu.
• Yinfekisoni: Yinfekisoni za bakitiriya oba akawuka.
• Embeera z’okuzimba: Endwadde ezireeta okuzimba mu mubiri, gamba ng’endwadde z’enkizi.
• Okukendeera kw’omusaayi olw’obutaba na kyuma.
• Eddagala erimu.
• Okulongoosa okuggyamu enseke: Omu ku mirimu gy’ennywanto kwe kuggyawo obutoffaali obukadde. Okugiggyawo kiyinza okwongera ku muwendo gw’obutoffaali obukola omusaayi.

Bizibu ki ebiyinza okubaawo olw’embeera eno?

Abantu abalina obulwadde bwa Essential Thrombocytosis (ET) bali mu bulabe bwa maanyi obw’okufuna ebizibu. Ebizibu bitono nnyo mu Reactive Thrombocytosis.

Obulabe obusinga obunene kwe kutondebwawo kw'omusaayi . Singa omusaayi guno gusibira mu musuwa ogugenda mu bwongo, guyinza okuvaako okusannyalala , era singa gusibira mu musuwa ogugenda ku mutima, guyinza okuvaako omutima okulwala . Ebizimba bino eby’omusaayi bisobola n’okutondebwa mu bifo ebirala, gamba ng’amawuggwe n’amagulu.

Tekitera nnyo, ET esobola okufuuka kookolo omulala ow’omusaayi, gamba nga leukemia, oba okuleeta enkovu mu busimu bw’amagumba (myelofibrosis). Era kiyinza okwongera ku bulabe bw’okufuna ebizibu ebimu ng’oli lubuto.

Naye teweeraliikiriranga. Bw’oba ​​olina ET, omusawo ajja kuba alondoola nnyo obulamu bwo era ajja kukuwa obujjanjabi obwetaagisa okutangira ebizibu nga bino.

Kino abasawo bakizuula batya ddala?

Obulwadde bwa Thrombocytosis businga kuzuulibwa nga bayita mu kukeberebwa omusaayi. Mu budde obutuufu, omuwendo gwa platelet ogusukka mu 450,000 buli microliter y’omusaayi gutwalibwa nga mungi. Omusawo ayinza okwagala okuddamu okukebera omusaayi gwo oluvannyuma lwa wiiki ntono okulaba oba omuwendo gw’omusaayi gwo gukyali mungi. Singa okubala kukomyewo mu mbeera eya bulijjo, ebiseera ebisinga tekiba kya kweraliikirira.

Singa omuwendo gwa platelet gweyongera okuba waggulu, ekiddako kwe kuzuula oba Reactive oba Essential. Kino kijja kwetaagisa okukeberebwa okulala okuwerako.

• Okukebera omusaayi okulala: Bino bikebera ebintu ng’ekyuma n’obubonero obulaga okuzimba, era binoonya enkula y’obutoffaali obutali bwa bulijjo wansi wa microscope.
• Okukebera obuzaale: Okukebera kuno kusobola okuzuula enkyukakyuka mu buzaale nga JAK2 , CALR1 , oba MPL1, ezitera okulabibwa mu Essential Thrombocytosis.
• Okukebera obusigo bw’amagumba: Kino kizingiramu okuggya sampuli entono ennyo ey’obusigo bw’amagumba okuva mu kifo ng’eggumba ly’ekisambi ng’obusumulula n’obukebera mu laboratory. Kino kiyinza okukakasa ddala embeera ya ET.

Kijjanjabwa kitya?

Enkola z’obujjanjabi zisinziira ku kika ky’obulwadde bwa thrombocytosis bw’olina n’obubonero bwo.

Ku bulwadde bwa Thrombocytosis obukola:

Kino kye kiseera obutoffaali obuyitibwa platelets bwe bweyongera nga buddamu obulwadde obulala. N’olwekyo, obujjanjabi bugendereddwamu ekivaako obulwadde buno . Okugeza, singa omuwendo gw’obutoffaali obukola omusaayi gweyongera olw’obulwadde, eddagala eritta obuwuka bwe liweebwa ku bulwadde obwo, omuwendo gw’obutoffaali obukola omusaayi gujja kudda mu mbeera eya bulijjo ng’obulwadde buwona.

Ku bulwadde bwa Essential Thrombocytosis (ET):

ET si bulwadde buwonyezebwa. Wabula kisobola okuddukanyizibwa obulungi okukendeeza ku bulabe bw’okuzimba omusaayi. Waliwo obujjanjabi obuwerako:

• Okulinda n’obwegendereza: Bw’oba ​​tolina bubonero bwonna ate ng’obulabe bw’okulwala omusaayi buba butono, omusawo ayinza okulondoola embeera yo ng’akebera omusaayi buli kiseera nga takuwa ddagala lyonna.
• Asipiin ow’omuwendo omutono: Oyinza okulagirwa empeke ya aspirin buli lunaku okuyamba okuziyiza omusaayi okuzimba. Naye jjukira nti totandika kumira aspirin ku bubwo nga tewebuuzizza musawo.
• Eddagala erikendeeza ku muwendo gw’obutoffaali obukola omusaayi: Eddagala nga Hydroxyurea, Anagrelide, ne Interferon alfa lifuga okukola kw’obutoffaali obukola omusaayi.
• Enkola y’okuggyamu omusaayi: Singa wabaawo akabi ak’amangu ak’okulwala omusaayi oguyinza okutta omuntu, omusaayi gwo guyinza okuyisibwa mu kyuma okusengejja obutoffaali obusukkiridde.

Ddi lw’osaanidde okulaba omusawo?

Bw’oba ​​ozuuliddwa ng’olina obulwadde bwa thrombocytosis, kikulu okwekebeza omusaayi buli kiseera ng’omusawo bw’akulagidde. Ekirala, buuza omusawo obubonero bw’osaanidde okuloopa amangu ddala singa bubaawo.

Okusingira ddala, bw’ofuna obubonero bw’okusannyalala oba okulwala omutima (e.g. okulumwa mu kifuba okw’amangu, okukaluubirirwa okwogera, okunafuwa ku ludda olumu olw’omubiri, okugwa mu maaso), genda mu kitongole ky’eddwaaliro eky’amangu (ETU) amangu ddala.