Oluusi owulira ng’okooye mu ngeri etaali ya bulijjo era ng’okooye awatali nsonga? Olina obutayagala mmere , okugejja oba okuziyira ? Oyinza n’okukiraba nti olususu lwo naddala enkokola n’amaviivi , lufuuse kitaka katono. Ebintu bino tobimala gabibuusa maaso. Ziyinza okuba akabonero akalaga nti waliwo ekintu ekikulu ekigenda mu maaso munda mu mubiri gwo. Leero twogera ku mbeera emu ng’ezo, Obulwadde bwa Addison .
Mu ngeri ennyangu, Obulwadde bwa Addison kye ki?
Lowooza ku mubiri gwaffe nga kkampuni ennene. Kkampuni eno erina ekibinja kya “chemical messengers ” abawanyisiganya obubaka okukuuma emirimu egy’enjawulo nga gitambula bulungi. Obusimu buno tubuyita .
Waggulu w’ensigo zaffe, ng’obukoofiira obutono bubiri, waliwo obusimu bubiri obutonotono. Zino ze tuyita endwadde z'ekibumba . Endwadde zino zikola obusimu bubiri obukulu obukulu mu bulamu bwaffe. Zino ze zino: cortisol ne aldosterone .
Obulwadde bwa Addison mbeera ng’endwadde z’ekibumba zoonoonese olw’ensonga ezimu era nga tezisobola kukola bungi bwa busimu buno obwetaagisa. Eno mbeera ya bbula nnyo. Naye kikulu nnyo okukimanya ku kino.
Obusimu buno obubiri bukola ki?
- Cortisol: Kino kiringa "omuddukanya situleesi" w'omubiri gwaffe. Obusimu buno buteekateeka omubiri okukola ku bulwadde, akabi n’okunyigirizibwa. Era ayamba okufuga puleesa, ssukaali mu musaayi, n’okukozesa ebirungo ebizimba omubiri, ebirungo ebizimba omubiri (carbohydrates) n’amasavu.
- Aldosterone: Obusimu buno bwe "kitereeza omunnyo n'amazzi" mu mubiri gwaffe. Ayamba ensigo zaffe okukuuma bbalansi y’omunnyo (sodium) ne potassium mu mubiri. Era kifuga puleesa yaffe.
Obusimu buno bwe buba butono, emirimu gy’omubiri gwonna gitaataaganyizibwa. Ekyo kye kibaawo mu bulwadde bwa Addison.
Bubonero ki obulaga obulwadde bwa Addison?
Obubonero bw’obulwadde bwa Addison bujja mpolampola, mpola mpola. Kale oluusi kiyinza okutwala akaseera okukitegeera ng’obulwadde. Obubonero buno bufaananako n’obw’endwadde endala ezitera okukwatibwa, n’olwekyo buyinza okutegeerwa obubi.
Laba ekipande wansi ku bintu ebikulu by’ogenda okulaba.
| Obubonero | Okunnyonnyola |
|---|---|
| Obukoowu obutawona n’okunafuwa kw’ebinywa | Okuwulira ng’okooye era nga tolina bulamu olunaku lwonna, ne bw’owummula otya. |
| Olususu lwa kitaka/oluddugavu (Hyperpigmentation) . | Okuddugala kw’olususu ku bitundu ng’enkokola, amaviivi, enkokola, emimwa, n’ennyindo. N’enkovu enkadde zisobola okufuuka enzirugavu. |
| Okubulwa okwagala okulya n’okugejja | Okubulwa okwagala okulya n’ekivaamu okugejja. |
| Puleesa eya wansi (Hypotension) . | Bw’owulira ng’oziyira naddala ng’oyimiridde ng’otudde, kiyinza okuba nga kiva ku puleesa okukka. Oyinza n’okubulwa amagezi. |
| Okwegomba omunnyo okuyitiridde | Omunnyo mu mubiri bwe gukendeera, buli kiseera wabaawo okwagala okulya emmere erimu omunnyo n’ebintu nga pickles. |
| Ebintu ebirala ebirimu | Okuziyira, okusiiyibwa, okulumwa olubuto, okuzimba, ssukaali omutono mu musaayi (hypoglycemia), obutabeera bulungi mu birowoozo, n’okugenda mu nsonga mu ngeri etategeerekeka mu bakyala. |
Biki ebivaako obulwadde bwa Addison?
Ekisinga okuvaako obulwadde bwa Addison bulwadde obuva ku busimu obuziyiza endwadde.Mu ngeri ennyangu, kino bwe kiba nti abaserikale b’omubiri gwaffe bennyini bagenda mu maaso ne balumba n’okusaanyaawo endwadde zaffe ez’omubiri (adrenal glands). Kino kye kivaako abalwadde ba Addison ebitundu 70%.
Okugatta ku ekyo, wayinza okubaawo ensonga endala.
- Yinfekisoni: Yinfekisoni eziwangaala nga akafuba ne siriimu zisobola okwonoona endwadde z’ekibumba.
- Kookolo: Obutoffaali bwa kookolo obubadde butondeddwa awalala busaasaana ne bugenda mu nnywanto z’omubiri (adrenal glands).
- Okuvaamu omusaayi munda: Okuvaamu omusaayi munda mu nseke z’ekibumba.
- Ebivaako obuzaale: Waliwo n’obulabe bw’okufuna obulwadde buno olw’embeera z’obuzaale ezimu.
- Okulongoosebwa: Bw’oba olongooseddwa okuggyamu endwadde z’ekibumba.
Kino okisanga otya Omusawo?
Bw’oba olina obubonero buno, laba omusawo w’amaka go amangu ddala nga bwe kisoboka. Ajja kukukebera n’okukusindika ew’omusawo omukugu bwe kiba kyetaagisa.
Okukebera omusaayi okuwerako kwe kusinga kukozesebwa okuzuula obulwadde buno.
1. Okukebera omusaayi okusookerwako: Kino kijja kukebera oba sodium (omunnyo) mu musaayi gwo mutono oba potassium mungi.
2. ACTH Stimulation Test: Kino kye kigezo ekisinga obukulu. Mu kino, obusimu obutono obuyitibwa ACTH obufulumizibwa obwongo bwo buweebwa ng’empiso. Mu muntu omulamu obulungi, empiso eno ereetera endwadde z’ekibumba okukola obusimu bungi obuyitibwa cortisol. Kyokka mu muntu alina obulwadde bwa Addison, endwadde teziddamu mu ngeri eno. Obulwadde buno bukakasibwa nga bakwata omusaayi ne bapima omuwendo guno ogwa cortisol.
Okugatta ku ekyo, bayinza okukolebwa CT scan okukebera oba waliwo yinfekisoni, kookolo, oba omusaayi mu nnywanto z’omubiri.
Ekisinga okuba eky’obulabe: Addisonian Crisis
Guno gwe mutendera ogusinga okuba ogw’akabi era ogw’amangu ogw’obulwadde bwa Addison. Obubonero butera okujja mpolampola, kale abantu abamu tebamanyi na nti balina obulwadde buno. Mu kiseera kino, singa omubiri guba ku situleesi nnyingi, gamba ng’obulwadde obulala, okulongoosebwa oba akabenje, obubonero buno buyinza okufuuka obw’amaanyi ennyo mu bwangu. Kino kiyitibwa ekizibu ky'Abaddisoni .
Eno mbeera ya mangu mu by’obujjanjabi era eyinza okuviirako okufa singa tezijjanjabwa.
Obubonero bw’obuzibu bw’Abaddisoni:
- Obulumi obw’amangu, obw’amaanyi mu mugongo, mu lubuto oba mu magulu.
- Okusesema okw’amaanyi n’ekiddukano, ekivaamu okuggwaamu amazzi mu mubiri.
- Okusannyalala okuva ku puleesa okukka ennyo.
- Okufiirwa okutegeera.
- Omusujja ogw’amangu n’obunafu obw’amaanyi.
Singa obubonero buno bulabika, .Omulwadde alina okutwalibwa mu kitongole ekijjanjaba abalwadde ab’amangu (ETU) mu ddwaaliro erikuli okumpi mu bwangu.
Obujjanjabi n’obulamu obwa bulijjo
Oyinza okutya okuwulira ku bulwadde bwa Addison, naye ekirungi nti waliwo obujjanjabi obukola ennyo .
Obulwadde buno buva ku busimu bwa bika bibiri obubula mu mubiri. Kale obujjanjabi kwe kuwa obusimu obwo ebweru mu ngeri y’empeke.
- Hydrocortisone: Empeke ya steroid edda mu kifo ky’obusimu obuyitibwa cortisol.
- Fludrocortisone: Empeke edda mu kifo ky’obusimu obuyitibwa aldosterone.
Eddagala lino lirina okulimira buli lunaku, nga ddala omusawo bw’alagira.
Ekisinga obukulu kwe butabuuka ddoozi emu ey’eddagala. Okubula wadde ddoozi emu kiyinza okuba eky’akabi.
Bw’oba olina yinfekisoni, omusujja oba ng’olongoosebwa, omusawo wo ajja kwongera ku ddoozi y’eddagala lino okumala akaseera okutangira ekizibu ky’e Addisonian.
Omuntu alina obulwadde bwa Addison bw’afuna obujjanjabi obutuufu , asobola okubeera n’obulamu obwa bulijjo ddala, obulungi .
Obubaka Obutwala Awaka
- Obulwadde bwa Addison mbeera ng’endwadde z’ekibumba ziremererwa okukola obusimu obumala obuyitibwa cortisol ne aldosterone.
- Obubonero obukulu kwe kukoowa buli kiseera, okugejja, puleesa okukka, n’olususu okuddugala.
- Bw’oba olina obubonero buno, tosattira era olabe omusawo mu bwangu.
- Wadde nga eno mbeera ya bulamu bwo bwonna, osobola okubeera n’obulamu obwa bulijjo ddala ng’omira eddagala buli lunaku.
- Bw’oba olina obulwadde bwa Addison, bulijjo yambala kaadi oba akakomo akalaga embeera yo. Kiyinza okuba ekiwonya obulamu mu mbeera ey’amangu.
- Obuzibu bwa Addisonian mbeera ya mangu eyeetaaga okujjanjabibwa mu bwangu. Kikulu okumanya obubonero.
Obulwadde bwa Addison, obusimu, endwadde z’ekibumba, cortisol, aldosterone, okukoowa buli kiseera, okuddugala kw’olususu, endwadde z’ekibumba, obutakola bulungi mu kibumba, puleesa okukka
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