Lowooza ku kino, ffenna tukitwala nti buli katoffaali mu mubiri gwo kalina DNA yo, nedda? Ekyo kye kintu ekikulu kye tumanyi ku buzaale. Naye, si bulijjo nnyo, omubiri gw’omuntu guyinza okuba n’obutoffaali obulina ekika kya DNA eky’okubiri ekitali kyabwe, era nga kya njawulo ddala. Kiwulikika nga kyewuunyisa katono, si bwe kiri? Mu busawo, embeera eno eyeewuunyisa tugiyita ‘Chimerism’. Tofaayo, si bulwadde. Ka tulabe ddala kye kiri.
‘Chimerism’ kye ki?
Mu ngeri ennyangu, chimerism kwe kubeerawo kw’obutoffaali bubiri mu mubiri gw’omuntu omu obuva mu bantu babiri ab’enjawulo mu buzaale. Kino kitegeeza nti obutoffaali obumu mu mubiri gwo buyinza okuba n’ekika kya DNA kimu, ate obulala buyinza okuba n’ekika kya DNA eky’enjawulo ddala.
Emu ku ngeri enkulu kino gye kiyinza okubaawo kwe kuzaala abalongo. Teebereza maama ng’asitudde abalongo mu lubuto. Mu wiiki ezisooka ez’olubuto, emu ku nkwaso eyinza okulemererwa okukula n’okubula olw’ensonga ezimu. Kino kiyitibwa obulwadde bwa Vanishing Twin Syndrome. Kino bwe kibaawo, obutoffaali obuva mu nkwaso ebuze bunywezebwa embuto endala ekula obulungi. Kale, omwana ajja kuba n’obutoffaali bwe n’obutoffaali okuva mu muganda we eyabula mu bulamu bwe bwonna.
Ebika by’obutoffaali obujja awamu mu ngeri eno bya njawulo ku birala. Ebiseera ebisinga, enjawulo eno elabibwa mu musaayi. Kiyitibwa ‘blood chimerism’. Kino kiri bwe kityo kubanga obutoffaali bw’omusaayi obukolebwa mu busimu bw’amagumba buba bwa maanyi era busobola bulungi okuyita mu nnabaana. Okusinziira ku kunoonyereza, abalongo nga 8% aba bulijjo bayinza okuba n’embeera eno. Mu baana abasatu, obusobozi buno bweyongera okutuuka ku bitundu 21%.
Biki ebivaako okukuba ebifaananyi (chimerism)?
Nga bwe twayogeddeko emabegako, abantu abamu bazaalibwa n’embeera eno. Wabula omuntu asobola okufuna chimerism mu bulamu bwe. Waliwo ensonga bbiri enkulu eziviirako kino. Katubimenye nga bwebiti.
| Okuleetera | Okunnyonnyola engeri gye kibaawo |
|---|---|
| Obulwadde bwa Chimerism obuzaalibwa nabwo | Eno ye ‘Vanishing Twin Syndrome’ gye twayogeddeko emabegako. Embuto emu ebula mu lubuto era obutoffaali bwayo ne bunyigibwa embuto endala ekivaamu ebika by’obutoffaali bibiri okusigala mu mubiri obulamu bwonna. |
| Chimerism eyafunibwa | Kino kikolebwa ng’obujjanjabi obutaasa obulamu. Ng’ekyokulabirako, lowooza ku ky’okukyusa ebitundu by’omubiri . Omuntu bw’afuna ekibumba okuva ku muntu omulala omulamu obulungi, ekibumba ekipya kikola ne DNA y’oyo amuwadde. Olwo omuntu afuna DNA ye ne DNA y’oyo amuwadde. Bwe kityo bwe kiri ne ku kusimbuliza obusimu bw'amagumba . Mu mbeera eno, obusigo bw’amagumba g’omuntu omulamu obulungi busimbibwa mu kifo ky’obusigo bw’amagumba obulwadde. Olwo obutoffaali bwonna obupya bukolebwa okuva mu DNA y’oyo agaba omusaayi. Kino kiyinza n’okukyusa omusaayi gw’omuntu. |
Waliwo obubonero bwonna obulaga kino?
Amawulire amalungi gali nti abantu abasinga abalina chimerism tebalina bubonero bwonna. Abantu bangi bagenda obulamu bwabwe bwonna nga tebamanyi nti balina embeera. Olw’okuba tewali kukeberebwa kwonna ku kyo, tekitera nnyo kuzuulibwa.
Kyokka oluusi kino kiyinza okuvaako obuzibu obutalowoozebwako naddala nga bakeberebwa DNA.
Teebereza, taata akola okukebera DNA okukakasa nti omwana ye taata. Naye ekivaamu kivaayo nti si ye taata w’omwana. Akakasa 100% nti mwana we yennyini. Ekiyinza okubaawo wano kiri nti taata bw’aba alina obulwadde bwa chimerism, DNA tebeera mu musaayi gwe oba amalusu ge, wabula mu butoffaali bwe obw’okuzaala (sperm). Ye DNA y’ow’oluganda eyabula mu lubuto. Olwo mu buzaale omwana n’akwatagana naye ddala ng’alinga omwana w’omu ku baganda be, kwe kugamba, omwana wa muganda we oba muwala wa muganda we.
Ebintu ebifaananako bwe bityo bisobola okutuuka ku maama, naye. N’olwekyo ebiseera ebisinga, chimerism ezuulibwa nga eva ku butakwatagana mu ngeri ey’ekifuulannenge mu kiseera ky’okukebera DNA nga kino.
Embeera eno esobola okuleetawo ebizibu eby’amaanyi?
Chimerism si bulwadde oba embeera ya bulabe, naye eyinza okuleeta obuzibu obumu singa oba togimanyi.
- Ensonga z’amateeka: Nga bwe kyayogeddwako emabegako, ebyava mu kukebera obuzaale obutali butuufu bisobola okuvaako ensonga ennene mu mateeka ezikwata ku kulabirira abaana. Wabaddewo ebikolwa eby’engeri eno ebiwerako okwetoloola ensi yonna.
- Ebizibu by’obwongo:Abantu abamu bayinza okufuna okuwuniikirira okutono mu birowoozo n’ensonga z’endagamuntu bwe bakizudde nti balina ebitundu by’omubiri gw’omuntu omulala.
- Amakulu mu by’obujjanjabi: Kiyinza okuba ekikulu okumanya embeera eno mu kiseera ky’okukwatagana kw’ebitundu by’omubiri nga tonnasimbibwa bitundu by’omubiri.
Naye bamaama tebeetaaga kweraliikirira ‘vanishing twin syndrome’. Singa kibaawo mu myezi esatu egisooka ng’oli lubuto, tekijja kutuusa bulabe ku maama oba omwana omulamu obulungi. Maama ayinza obutalaba bubonero bwonna okuggyako okuvaamu omusaayi omutono.
Obubaka Obutwala Awaka
- Chimerism kwe kubeerawo kw’ebika bya DNA bibiri mu kiramu kimu. Kino kitera okubaawo nga kiyita mu kunyiga obutoffaali okuva mu balongo mu lubuto oba okuyita mu kusimbuliza ekitundu ky’omubiri/obusimu bw’amagumba.
- Eno si mbeera ya bulabe. Abantu abasinga abalina chimerism tebalina bubonero bwonna.
- Ekizibu ekikulu kiva ku kukebera DNA naddala mu bintu ng’okukebera obuzaale, ng’ebivaamu biyinza obutakwatagana.
- Bw’oba olina ekizibu ekitannyonnyoddwa ku bivudde mu kukeberebwa DNA, yogerako n’omusawo wo ku ky’okuba oyinza okuba nga okola chimerism.
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