I naute hian an thluaka kawngpui pawimawh tak a hloh a nih chuan engtin nge ni ang? (Corpus Callosum atanga agenesis - ACC) 1. A rilru a hah lutuk chuan a rilru a buai em em a.

I fa thluak chanve pahnih inzawmna chu a insiam tha lo mai thei tih i hre ngai em? Hei hi a hlauhawm deuhin a lang thei a, mahse lungngai suh. Hemi chungchang hi chipchiar takin sawi ila, awlsam takin. Hetiang dinhmun hi ‘Agenesis of the Corpus Callosum’ kan ti a, a tawi zawngin (ACC) kan ti bawk.

Agenesis of the Corpus Callosum (ACC) chu eng nge ni?

A awlsam zawngin, `(Agenesis of the Corpus Callosum - ACC)` hi pianpui natna a ni a, i thluak dinglam leh veilam (``hemispheres`` tia koh bawk) inkara information inbiakpawhna atana puitu nerve fibers thick band ``Corpus Callosum`` chu a bo vek emaw, a then emaw a awm lo.

I thluak kil hnih chu lui kam hrang hrang pahnih ang maiin ngaihtuah rawh. Heng bank pahnih inkarah hian information kal leh haw tur chuan bridge a awm a ngai a ni lawm ni? Chu chu `(Corpus Callosum)` chu a ni. He bridge hi thluak sir lehlamah an inbiak a, thu inhrilh tawnna tura puitu a ni. Chuvangin `(ACC)` chungchangah chuan he kawngpui plank te hi tlem a tlem a, a nih loh leh bridge hi a bo vek ang mai a ni. A chang chuan he kawngpui hi i pel thei a nih pawhin a harsa hle.

He ``Corpus Callosum`` hian kan hriatna, kan chetna leh kan ngaihtuahna buaithlak tak takte chu a thunun thei a ni. ``ACC`` dinhmun hian hmasawnna lama harsatna, zirlai lama harsatna, fine motor skills lama harsatna te a thlen thei a ni. Mahse, heng symptoms te hi enkawl dan tur a awm.

`(ACC)` chi hrang hrang a awm em?

Ni e, `(ACC)` hi chi hnih lian tak a awm a:

• Complete agenesis: Hetiang a nih chuan corpus callosum hi a lo piang kim lo.
• Partial agenesis (hypogenesis emaw dysgenesis emaw an ti bawk): Hetah hian corpus callosum thenkhat chauh a awm lo.

Heng chi hrang hrangte hi hetiang hian then belh theih a ni:

• Isolated: Hei hian Corpus Callosum chauh a nghawng a ni.
• Complex: Hetiang a nih chuan Corpus Callosum bakah hian thluak hmun dang pawh a nghawng thei bawk.

Naupang `(ACC)` vei te hian eng symptoms nge a neih?

ACC symptoms hi corpus callosum inrawlhna leh thluak hmun dang a nghawng leh nghawng loh a zirin a danglam thei. A lan chhuah dan tlangpui chu:

• Hmasawnna tlai: Entirnan, thil inher, thut, kal, leh thusawi ang chi te hi a tlai thei.
• Thil hriatna lama harsatna emaw, rilru lama harsatna emaw.
• Hmuh, hriat leh thusawi harsa.
• Seizures a awm thin.
• Nu hnute pek harsatna (nausen).
• A tul lo taka taksa ruh tihkhauh emaw, tihzauh emaw.
• Lu lian leh te tak te ang lo takin.
• Hydrocephalus (hei hi a tlem deuh).

Nu leh pa i nih angin, i fa kum hnih hmasa berah heng chhinchhiahna thenkhat hi i hmu thei a ni. Mahse, a na lo deuh ṭhenkhatah chuan i fain sikul a kal theih hma loh chuan natna lan chhuahna lian ber berte chu a lang lo thei a ni. Entîr nân, i fain hetiang thilte hi a harsat tih i hmu hmasa mai thei:

• Sensory-motor information enkawl dan: Chunglam atanga ball lo kal man ang mai.
• Reduced cognitive speed: Naupang dang aiin puzzle chinfel nan hun a duh rei zawk.
• Reasoning leh problem-solving: Step engemaw zat awmna thupek zawm harsa.

`(ACC)` nen hian eng nungchang lama harsatna nge inzawm theih?

Hetiang ang nungchang lama harsatna hi `(ACC)` condition nen pawh hmuh theih a ni:

• Clumsiness: Kal laiin tlu leh tlu fo thin.
• Taksa veilam leh dinglam inrem harsa: cycle khalh emaw, tui chawi emaw ang chi thil tih hunah.
• Kut leh mit inrem lohna: needle thread emaw musical instrument tum emaw ang chi.
• Mut harsatna: Mut harsa, mut laiin harh leh mut a kal (parasomnias) .

Naupang tam tak chuan ACC bakah hian neurodevelopmental disorder ADHD te pawh an nei thei bawk.

`(ACC)` awm chhante chu engte nge ni?

Dik tak chuan doctor-te chuan engvangin nge corpus callosum hi beisei angin a lo thanglian loh tih an la hre chiang lo. Mahse zirchianna chuan a tam zawkah chuan a hnung lamah hian genetic cause a awm tih a tarlang. Chung zinga ṭhenkhat chu:

• Aneuploidy: Taksa cell-a chromosome pakhat extra emaw, pakhat aia tlem emaw awm.
• Chromosome rearrangements: Chromosome pakhat insiam dan a inthlak danglam thin. Entirnan, segment pakhat chu a inthen a, chromosome pakhatah a inzawm leh (inversion) emaw, chromosome dangah a inzawm leh emaw (translocation).
• Genetic variants: Gene (DISC1) a danglamna hian symptom a thlen thei.

ACC hi damdawi lam thil dang nen a awm thei em?

Ni e, `(ACC)` chi thenkhat chu pianpui natna dang nen a awm dun thei a ni. Entirna thenkhat chu:

• `(Aicardi natna)`
• `(Apert syndrome)` tih a ni
• `(Dandy-Walker natna)`
• `(Joubert natna)`
• `(L1 syndrome)` tih a ni
• `(Schizencephaly natna)`
• `(Trisomy 13)` tih a ni
• `(Trisomy 18)` tih a ni

Hengte hi damdawi lam thumal buaithlak deuh deuh a ni a, mahse i doctor chuan he thu hi a hrilh belh ang che.

`(ACC)` tana risk factors te chu engte nge ni?

Naupai laia harsatna thenkhat chuan nausen pum chhunga naute thanlenna a tichhe thei a ni. Hei hian ``(ACC)`` vei theihna a tipung thei a ni. Heng risk factor thenkhat chu:

• Naupai kar 12 leh kar 24 inkar chhunga nausen natna hrik emaw, chhiatna emaw a awm.
• Fetal alcohol syndrome hi nuin zu a in vang a ni.
• Phenylketonuria tih hming pu natna a ni.

`(ACC)` dinhmun hi engtin nge kan hriat theih ang?

Doctor chuan naupai kar 16-na hnua ultrasound scan-naah ACC a ringhlel thei a ni. Mahse, naute pian hnuah definitive diagnosis tih a ni tlangpui.

Doctor pakhatin taksa enfiahna leh test dang a ti ang. Physics exam neih chhung hian doctor chuan i symptoms leh medical history te a zawt ang. Naupangteah chuan nu leh pate hnenah naupang chu kum nena inmil hmasawnna milestone (e.g., thut, kea kal) a thleng tawh em tih an zawt ang.

Diagnosis finfiah nan doctor chuan brain imaging test neih a ti thei bawk. Computed tomography (CT) scan emaw magnetic resonance imaging (MRI) scan emaw hmangin corpus callosum chu a then emaw, a block vek emaw tih hriat theih a ni.

He natna hi natna dang nen a awm dun nia rinhlelhna a awm chuan test dang neih belh a ngai mai thei.

`(ACC)` enkawlna tur engte nge ni?

ACC enkawlnaah hian natna lan chhuah dan enkawlna kawnga tanpui hi a pawimawh ber a ni. Hei hian a huam thei ang:

• Seizure control nan antiseizure damdawi pek.
• Sikul-a special education programme-a hmalakna hmasa emaw, tel emaw.
• Taksa lam enkawlna.
• Occupational therapy hmanga enkawlna.
• Thusawi hmanga enkawlna.
• Visual therapy hmanga enkawlna.
• Hydrocephalus natna vei tan shunt dah luh.
• Cognitive behavioral therapy hmanga enkawlna (cognitive behavioral therapy) a ni.

Enkawl dan hi mi hrang hrangah a inang lo. I doctor chuan i mamawh ang zela enkawlna tur ruahmanna a pe ang che.

`(ACC)` dinhmun nen chuan nun chu eng ang nge ni ang?

He dinhmun hian mi hrang hrang a nghawng dan a inang lo. I hriatna (cognitive function), motor thiamna leh nungchang te a nghawng thei a ni. I corpus callosum chhiatna zau zawng hian i prognosis a hril thei a ni. A nasat dan pawh a inang lo thei.

Mi thenkhat tan chuan ACC hian nitin hnathawhnaah nghawng tlemte chauh a nei thei. Mi dangte tan chuan doctor tam tak enkawlna hnuaia dam chhung enkawl a ngai thei bawk. I doctor chuan i dinhmun thlirletna chungchang a hrilh thei a, chu chu i tan a danglam bik a ni.

Infiamna, thiltih, sikul, a nih loh leh ni tin hna thawhnaah mahni chauha tel harsa i ti thei. Hei hian i rilru hriselna leh rilru hriselna a nghawng thei a ni. Mental health professional, i care team-a mi dangte nen, heng symptoms-te hian a nghawng dan che chu insiamrem leh enkawl turin a pui thei che a ni.

ACC hian dam rei zawngah nghawng a nei em?

Isolated ACC hian i dam chhung a nghawng nghal lo. Mahse, ACC nen hian natna dang i neih chuan, emaw, a natna lan chhuah dan hian thluak hmun dang a nghawng a nih chuan i dam chhung hi a danglam thei a ni.

`(ACC)` hi ven theih a ni em?

A chhan dik tak hriat a nih loh avangin ACC ven dan tur a awm lo. Amaherawhchu, nu leh pa naupai te chuan naupai laia mahni inenkawlna tha tak hmangin ACC vei nau neih theihna an tihziaawm thei a ni. Hei hian zu in loh te, hri kai leh chetsualna laka invenna te a huam a ni. Doctor chuan i hriselna leh i nausen piang lai hriselna enkawl turin a pui thei che a ni.

Chhungkaw din i tum a, nausen genetic condition nei i neih theih dan tur i hriat duh chuan genetic testing pawh i ti thei bawk.

`(ACC)` vei naupang chu nun pangngaiin a nung thei ang em?

Ni e, a thleng thei. Mahse i tana "normal" chu mi dangin "normal" anga an ngaih nen a danglam thei. I fa chu a la inkhel thei a, thil hlimawm takah a la tel thei a, sikul a la kal thei a, midangte nen pawh a la inkawp thei bawk. Harsatna engemaw zat a awm thei a, mahse a tul chuan i doctor-te chuan chutiang thila insiamrem turin an pui thei che a ni.

Engtikah nge doctor i hmuh ang?

I fain hmasawnna tur thil pawimawh tak tak a neih loh chuan, emaw, an nungchang emaw, an hnathawh danah emaw inthlak danglamna i hmuh chuan i doctor nen inbia ang che. I fa chu i hre chiang ber. Chuvangin ACC chhinchhiahna i hmuh chuan i fa doctor nen inbia ang che.

Doctor hnena zawh tur pawimawhte chu engte nge ni?

He natna hian mi zawng zawng a nghawng dan a inang lo avangin, i doctor hnenah hetiang zawhna hi zawh hi ngaihtuah rawh:

• ``Corpus Callosum'' ah hian engzat nge tlakchham?
• `(ACC)` ang chi symptoms thlen thei damdawi dang a awm em?
• Eng ang enkawlna nge i rawt?
• Enkawlna hian side effect a nei em?

`(ACC)` tih hian rualbanlo tihna a ni em?

ACC vang hian rilru lama harsatna a awm thei a ni. Mahse, ACC nei naupang zawng zawng hian rilru lama harsatna an nei vek dawn lo. Hei hi corpus callosum a nghawng nasat danah a innghat a ni.

I fain an thluak hmun thenkhat a hloh tih i hriat chuan lungkhamna a thlen thei a ni. An hmalam hun chu eng ang nge ni ang tih i ngaihtuah mai thei, a bik takin thluak veilam leh dinglam te hian inbiakpawhna an neih harsat chuan.

Nu leh pa tan thil engemaw (a tawpah) .

I fa enkawltu team chuan Agenesis of the Corpus Callosum (ACC) chungchang leh i fa i tanpui theih dan tur hriatthiamna an pe thei che a ni. Case tin hi a nasat dan a inang lo va, chuvangin i fa hian symptom tam tak a nei lo thei a, a nih loh leh an symptoms chu a na zual thei bawk. Mahse, doctor-te chuan i fate tan individualized treatment plan an siam ang. Beisei tur chungchanga zawhna i neih chuan i fa doctor-te nen inbia ang che. Nangmah chauh i ni lo tih hre reng la, tanpuina a awm bawk.

` Agenesis of the Corpus Callosum, ACC, thluak thanlenna, corpus callosum, hmasawnna tlai, naupang hriselna, genetic natna