HATTR amyloidosis tih hming pu genetic condition hmuh tur awm lo tak i neih thu i hriat chuan i lungngai hle mai thei. A nihna takah chuan natna hmuh tur awm lo tak a ni. Khawvel pumah mi 50,000 chauhvin he natna hi an vei a ni. I hriat veleh hlauhna leh buaina i neih hi thil pangngai a ni. A awlsam zawngin sawi ila, he natna hi kan taksaa TTR an tih gene a mutation avanga lo awm a ni. Chuvang chuan protein chi danglam tak amyloids an tih chu kan thinlung, kal, nervous system, leh gastrointestinal system-ah te a awm a. Tichuan chu taksa pengte chu a thawk tha thei lo. Doctor rawn hmuh hmasak ber tur i kal hunah chuan zawhna tam tak a zawt ang che. Inbuatsaih lawk a pawimawh hle. Tichuan nang leh doctor chuan i tan enkawlna tha ber i thlang thei ang.
Doctor hmu tura i kal hmain engtin nge i inbuatsaih thin?
Doctor pan hmain heng point te hi ngaihven hmasak phawt a tha.
I chhungkaw damdawi lam chanchin dik takin hre rawh
hATTR amyloidosis hi genetic natna a ni. Medical lamah chuan ``autosomal dominant`` condition a ni. Chumi awmzia chu i nu leh pa zinga pakhatin he natna thlentu gene mutation a neih chuan 50% in rochun theihna chance i nei tihna a ni. I nu leh pa emaw, i unau emaw, i fate zinga pakhatin he natna hi a vei tih hmuhchhuah a nih chuan, natna lan chhuahna nei lo mah la, genetic test neih a pawimawh hle.
I chhungkuaa mi pakhatin natna a vei vang mai mai chuan 100% in i vei theihna a ni lo tih hre reng ang che. Mahse gene i neih leh neih loh hriat hian enkawlna i hmu thei a ni .
Test report i tih tawh zawng zawng kha la vek rawh.
TTR gene mutation zawng tura genetic testing i neih tawh chuan i doctor hnenah hrilh rawh. Tin, i test result-in gene i nei tih a nemnghet a nih chuan i doctor chuan test dang engemaw zat tih belh leh turin a rawt bawk ang. Hei hi a chhan chu hATTR natna hian taksa peng dang, thinlung, thin, leh kal (kidney) te pawh a nghawng thei a ni. Tun hnaia heart test (echocardiogram) emaw thisen test emaw i neih chuan chu report zawng zawng chu rawn keng vek rawh.
I damdawi ei tur list keng la.
I doctor chuan i damdawi ei zawng zawng chu a hre duh ang. Hei hian i doctor-in a pekte chauh ni lovin, over-the-counter pain reliever, vitamin leh supplement i ei zawng zawng pawh a huam tel bawk.
Doctor-in a zawh theih zawhnate
I zawhnate chhân tûra inpeih reng chuan i doctor-in i tâna enkawlna ṭha ber tûr a relsak ang. Zawhna i neih apiang zawh theihna hun a pe bawk ang che.
Doctor-in a zawh theih che chu tawi te tein kan rawn tarlang e.
| Zawhna chhanna hmun | Eng nge zawh theih che leh i hriat tur |
|---|---|
| Chhungkaw history-a natna nei | "I chhungte zingah hATTR nei dang an awm em?" tiin an zawt a. I chhungkuaa mi tu emaw chuan thinlung natna, progressive neuropathy , carpal tunnel syndrome , a nih loh leh intestinal problems a nei tawh mai thei. hATTR an nei a, an hre lo pawh a ni mai thei. Chuvangin he thu hi an hnenah share ve rawh. |
| Genetic leh diagnostic test te a ni | "Genetic testing i nei tawh em?" tiin an zawt a. hATTR hian taksa peng hrang hrang a nghawng avangin hriat a harsa thei hle. I doctor chuan a hnuaia test te hi a rawt thei ang: biopsy (test atan tissue thenkhat lak), thisen test, i thinlung enfiah nan echocardiogram emaw cardiac MRI emaw, leh nerve hnathawh dan enfiah nan nerve conduction test te . |
| Lung lam nena inzawm natna lan chhuah dan | "Thinlung natna, thawk hah, exercise lak harsat, i ke a hring ang chi symptom i nei em?" hATTR hian heng proteins te hi thinlungah a tipung thei a, heart attack, heart disease, emaw heart muscle thickening (hypertrophic cardiomyopathy) te a thlen thei a ni. Heng symptoms te hi i neih chuan cardiologist hnenah refer nghal i ni ang. |
| Mit hmuhna lama harsatna a awm | "I mit hmuhnaah hian danglamna i nei em, floater ang chi?" TTR gene mutations 20% vel hian mit a nghawng a ni. Mit lama danglamna a awm chuan mit lam doctor hnenah enfiah tur a ni . |
| Kal leh nerve lama harsatna nei | "Kea kal harsatna i nei em?" hATTR natna lan chhuahna hmasa ber leh langsar ber pakhat chu i kut leh kea nerve tihchhiat (peripheral neuropathy) hi a ni. Hei hian natna, rilru hahna, leh tingling ang chi symptoms a thlen thei. Chûngte chuan i nun a nghawng a nih chuan, occupational therapy ang chi thilte chu i ngaihtuah a ngai mai thei . |
| Autonomic nervous system lama harsatna awm thei | "I thawmhnaw hah lutuk, riltam leh chaw ei kham inthlak danglam emaw, i zun control harsa i nei em?" Hengte hi kan thunun theih loh, kan thinlung chakna, thisen sang, leh chaw ei dan ang chi thil control thei autonomic nervous system-a harsatna a ni. Heng symptoms te hi i neih hian i hATTR condition a na zual zel tih hriattirna a ni thei. |
Doctor chuan enkawl dan tur a sawi bawk.
I dinhmun a finfiah hnuah doctor chuan enkawl dan tur a sawipui ang che.
I damdawi i ei tawh em?
Tunah hian hATTR control leh a kal zelna tikhawtlai thei tur damdawi engemawzat pawm a ni. Entirnan, ` Eplontersen (Wainua)`, `inotersen (Tegsedi)`, `patisiran (Onpattro)`, `vutrisiran (Amvuttra)`, `tafamidis (Vyndamax)`, leh `tafamidis meglumine (Vyndaqel)` te hi a ni. Heng damdawi te hi i lo hmang tawh em tih te, a puih che em tih te, side effect a thlen em tih te doctor hnenah hrilh a pawimawh.
Liver transplant chungchangah engtin nge i ngaih?
Kum sawm tam tak chhung chu hATTR enkawlna tha ber chu liver transplant a ni. Mahse, harsatna a thlen theihna a sang hle a, a bik takin thinlung lam harsatna a thlen thei a ni. Zirchianna thar atanga a lan dan chuan damdawi thar thenkhat chu liver transplant ang maiin a hlawk thei a ni. Chuvangin he surgery leh enkawlna dangte thatna leh that lohna chungchang hi i doctor nen in sawi dun thei ang.
Clinical trial-ah hian tel ve i duh em?
Doctor ten hATTR damlo enkawl dan tha zawk an zawng fo thin. Chutianga tih theih dan pakhat chu clinical trial hmanga tih a ni. Nimina damdawi pawmpui tawh zawng zawng chu hetiang hian test vek a ni. Hei hi mipui zahawmte tana hman theih a nih hmaa enkawlna thar neih theihna hun tha tak a ni. Mahse risk engemaw zat a awm. Hemi chungchang hi i doctor hnenah pawh i zawt thei bawk.
Take-Home Thuchah a ni
- hATTR amyloidosis hi natna hmuh tur awm lo, thlahtute atanga lo chhuak a ni. I hriat hunah lungkhamna i neih hi thil pangngai a ni.
- Doctor hmu tura i kal chuan i chhungkaw medical history, test result i neih tawh leh i damdawi ei tur list keng la.
- I natna lan chhuah dan (ril na, thawk harsa, i ke leh ke ruh, i mit a inthlak danglam) te chu engmah thup lovin doctor hnenah hrilh rawh.
- I doctor nen enkawlna kawng hrang hrang (damdawi, surgery, damdawi lam zirchianna) chungchangah zalen takin sawi la, zawhna i neih zawng zawng zawt rawh.
- Natna dik taka i hriat chian a, enkawl dan tur dik tak i dawn chuan he natna nen hian hlawhtling takin i nung thei ang.
💬 Comments (0)
Comment a la awm lo. Hetah hian i comment hi a vawikhatna atan add rawh.
I comment kha add rawh