Immunotherapy for Breast cancer: I taksa chakna hmangin cancer hi do rawh

Cancer enkawl dan kan ngaihtuah hian chemotherapy leh radiotherapy ang chi enkawlna kan ngaihtuah nghal mai thin a ni lawm ni? Mahse, hengte bakah hian, kan taksa ngeia kan invenna (defence system) hmanga cancer cell do thei tur, enkawlna thar, changkang tak a awm tih i hria em? Chu chu immunotherapy kan tih chu a ni.

Chuti a nih chuan, a awlsam zawngin, immunotherapy chu eng nge ni?

Immunotherapy hi i taksa ngeia immune system , a nih loh leh ‘a tiharh’, hnute cancer cells hriat theihna, a beih leh tihchhiat theihna tura puitu damdawi a ni. Hmelma thup (cancer cell) zawng chhuak tur leh tihchhiat tumin nangmah ngeiin defense force te training tir ang mai a ni.

Tunah hian doctor-te chuan he enkawlna hi triple-negative breast cancer, enkawl harsa chi chi khat tan an hmang ber a ni. Metastatic breast cancer atan pawh hman a ni . Hei bakah hian hnute cancer chi dang, HER2-positive leh ER-positive te tana immunotherapy hman tangkai dan tur zirchianna pawh kalpui mek a ni.

He enkawlna hian engtin nge kan taksa chhungah hna a thawh?

Hei hi hrethiam tur chuan entirnan tlem han la ila. Kan immune system hi kan rama police te ang a ni tih han ngaihtuah teh. Police hna chu mi sual leh rukrute hriatchhuah leh man hi a ni. Kan taksaa cell hrisel leh cancer cell te hian an chung lamah protein bik an nei vek a. Heng antigens te hi kan ti a .

Mahse cancer cell te hi rukru fing tak tak an ni. Cancer cell thenkhat chuan an chunglam protein te chu an thlak danglam a, an inthuam a, immune system, police te hnenah, "Ka chhe lo, nangmahni zinga mi ka ni," tiin an lantir a ni. Tichuan police te hian he rukru hi an hre thei lo. He hna fing tak hi tihbuai tumin Immunotherapy hi a awm a ni.

He enkawlna hian kawng lian pahnih a thawk thei a:

• Active Immunotherapies: Hei hian nangmah ngeiin i taksa hriselna (immune system) ‘training’ bik pek a huam a ni. Immune system hi cancer cell-ah chauh hmuh theih marker (antigen) bikte hriatchhuah a, anmahni chauh bei tura zirtir a ni.
• Passive Immunotherapies: Hei hi lab-a siam damdawi bik taksaah inject a ni. He damdawi hian kan taksa hriselna (immune system) pui tura lo kal ‘special forces’ unit angin hna a thawk a ni. Damdawi hian cancer cell-ah direct-in a kal a, a mask a phelh a, a pholang emaw a ni.

Hnute cancer tan hian eng ang immunotherapy damdawi nge pek thin?

Tunah hian khawvelah hian hnute cancer enkawlna atana pawm immunotherapy damdawi chi hnih lian tak a awm a.

1. Pembrolizumab (Keytruda®): Hei hi damdawi hman tam ber a ni. A bik takin triple-negative hnute cancer tan pek a ni. He damdawi hian cancer cell-te’n anmahni inthup nan an hman protein bik pakhat chu a block a, hna a thawk a ni. Hei hian immune system chuan awlsam zawkin cancer cell te chu a hre thei a, a bei thei bawk. A chang chuan he damdawi hi operation hma leh operation hnuah pek thin a ni a, chu chu cancer a lo let leh tawh loh nan a ni.

2. Dostarlimab (Jemperli®): He damdawi hi damlo enkawlna dang hnua cancer a darh tawh, an cancer cell-a genetic marker (tumor marker) bik nei te tan pek thin a ni.

Engtin nge he enkawlna hi pek a nih a, eng chen nge pek a nih?

Immunotherapy damdawi hi vein hmanga pek a ni a, chu chu saline solution ang chi, intravenous (IV) injection an ti a ni. He enkawlna hi kar 3 atanga kar 6 danah pek thin a ni tlangpui. I dinhmun azirin he enkawlna hi thla engemaw zat atanga kum hnih thleng a ni thei. I doctor chuan schedule a rel ang.

Immunotherapy hi engtiang chiahin nge a hlawhtlin?

He enkawlna hi a la thar deuh hlek a ni. Mahse, zirchianna atanga a lan dan chuan, a bik takin triple-negative breast cancer vei tan chuan immunotherapy leh chemotherapy inkawp hian chemotherapy chauh aiin dam rei theihna hun a ti tha zawk a ni. Hei hi a beisei awm tak zet a ni.

Tunah hian khawvel hmun hrang hrangah clinical trial za tam tak kalpui mek a ni. Hengte hian immunotherapy hi hnute cancer chi dang atan hman theih a nih leh nih loh en a ni a, enkawlna awmsa pawh tihchangtlun theih a nih leh nih loh enfiah a ni. Chuvangin he enkawlna hi nakin lawkah cancer dona kawngah ralthuam pawimawh tak a ni thei ang.

Side effect awm thei te chu engte nge ni?

Enkawlna dang ang bawkin immunotherapy hian side effect a nei thei a ni. Mahse, hei hian mi zawng zawng a nghawng dan inang lo. Mi thenkhat chuan harsatna tenau chauh an nei thei a, thenkhat erawh chuan side effect engmah an nei lo thei thung. Enkawlna i tan hmain i doctor nen a side effect awm thei chungchang sawipui a pawimawh hle a, chu chu i hriat chian a pawimawh hle.

Engtikah nge Doctor ka hmuh ang?

A chunga tarlan side effect na tak tak i neih chuan i doctor hnenah i hriattir nghal tur a ni . Side effect tenau tak pawh ni engemaw zat chhunga a ṭhat loh emaw, a nasat lutuk emaw chuan doctor hnenah hrilh rawh. Enkawl laia i taksaa inthlak danglamna awm apiang ngaihven a, chu chu doctor nen inbiakna neih a pawimawh.