Lennox-Gastaut Syndrome (LGS) hi eng nge ni? Kan sawi dawn nia!

I fa te hian seizures a nei fo em? Zirna leh nungchangah inthlak danglamna lian tak a nei em? Chutiang a nih chuan ka sawi tur hi i tan a pawimawh hle mai thei. Vawiin hian Lennox-Gastaut Syndrome , emaw (LGS) a tawi zawngin, epilepsy natna khirh tak leh enkawl harsa tak chungchang kan sawi dawn a ni. Hei hi kum naupan lai atanga tan theih a ni. Mahse, lungngai suh, tunah chuan damdawi thar leh enkawlna thar a awm ta.

Lennox-Gastaut syndrome (LGS) hi eng nge ni tak tak? Tuin nge dawng?

A awlsam zawngin sawi ila, LGS hi epilepsy natna khirh tak a ni a, naupan lai atanga tan a ni a, a tlangpuiin kum 10 an tlin hmain a intan a, a bik takin kum 3 leh 5 inkar a ni a , mipa naupangah chuan a tam zawk deuh hlek a ni. Amaherawhchu, a awm dan tlangpui a ni lo. Mi maktaduai khatah mi pakhat atanga pahnih vel a nghawng a ni. Epilepsy vei zawng zawng zinga 1% atanga 2% velin LGS an nei a ni.

Engtin nge hei hian kan taksa a nghawng?

Epilepsy hi thluaka electrical signal, a nih loh leh information, cell inkara inthlunzawmna natna a ni. (LGS) hi epilepsy natna na zawk a ni. A chhan hrang hrang a awm a:

• LGS-ah chuan seizure chi khat aia tam a awm thin. Heng seizure chi hrang hrang thenkhat hian naupang hliam na tak a thlen tam zawk.
• Heng seizures te hian thluak ngei pawh a tichhe thei a ni. LGS vei naupangte hian thluak chhiatna nasa tak an nei thei a, zirlai harsatna an nei thei a, an thanlenna pawh a tlai thei bawk. Chumi awmzia chu naupangin a thil zir tawh, kea kal leh thusawi ang chite chu a hloh emaw, a theihnghilh emaw a ni thei tihna a ni. Hei hi dinhmun lungchhiatthlak tak a ni.
• (LGS) hi a tlangpuiin enkawlna lakah a do thei hle. Chumi awmzia chu damdawi hmanga thunun a harsa tihna a ni. Damdawi hi enkawlna hmasa ber a ni a, mahse a tam zawkah chuan damdawi chi hrang hrang a rualin pek thin a ni. An pek pawh nise, damdawi chauh hian seizures chu a titawp vek thei lo.

(LGS) natna lan chhuah dan chu engte nge ni?

LGS vei naupang hian symptom hrang hrang a lantir thei a ni. Ṭhenkhat chu nitin nunah leh thil tihnaah hriat theih an ni a, ṭhenkhat erawh chu seizure lai chauha hriat theih an ni thung.

Zirna leh nungchang lama harsatna a awm

LGS vei naupangte hian zirlai harsatna leh nungchang lama harsatna an neih hi thil awmze nei tak a ni . Hengte hi seizures tan hnu lawkah a lo lang thei a, seizures chhunzawm zel chuan a na zual thei bawk. Heng zirlai leh rilru lama harsatnate hi a awm reng fo a, chu chu puitlin thlengin a awm reng thei tihna a ni.

LGS vei naupangte hian zirlai, ṭhian siam leh midang nena inbiak pawhna kawngah harsatna an nei ṭhin. An rilru put hmang tihreh harsa an ti thei bawk. Naupang thenkhat pawhin Autism Spectrum Disorder vei naupangte natna lan chhuah dan inang an nei thei bawk .

Seizure stage a ni

Seizure hi a tlangpuiin stage thum-ah a awm thei a:

1. Prodrome emaw aura: Hei hi mi thenkhatin seizure an neih hmaa an tawn thin a ni a, a awm fo lo nain. Hei hi rilru nuam lo tak a ni thei. Hetih lai hian mit hmuhna inthlak danglamna, hriatna dang inthlak danglamna emaw, rilru put hmang emaw, nungchang emaw inthlak danglamna a awm thei.

2. Seizure: Hei hi seizure a awm lai a ni. Hei hi seizure chi hrang hrang a zirin a danglam thei (a hnuaiah hian seizure chi hrang hrang kan sawi dawn a ni).

3. Post-seizure recovery: Hei hi seizure a tawp hnu hun chhung a ni. Hei hi miin a hriatna famkim a neih leh hun a ni.

LGS-a seizure chi hrang hrang hmuh theih

LGS-ah hian seizure chi hrang hrang hmuh tur a awm a. Seizure chi hrang hrang leh a nghawng dan tlangpui chu hetiang hi a ni:

• Atonic seizures te hi: 1.1.
• Muscle control hloh/fainting: Hei hi "drop attack" an ti bawk a, a chhan chu control hloh nghal a, leiah a tla a, puppet a hrui a chhe tawh ang mai a ni. Hei hi a hlauhawm hle a, a chhan chu naupangin an tluk hunah thununna a nei lo va, a lu, a kawr, a rilru leh a hnungzang-ah hliam na tak, nunna atana hlauhawm tak pawh a tuar thei a ni.
• Partial loss of consciousness: He seizure hian hriatna hloh vek a thlen lo thei.
• Hun rei lote chhung: Heng seizures te hi a rei lo hle a, second tlemte ang maiin.

• Tonic convulsions te hi a awm a:
• Whole body stiffness/freezing: Hei hi taksa ruh zawng zawng a inzawm khawm thut a, taksa chu lungah a chantir ang maia a nghet vek a ni.
• A special pose: Leia an awm lai hian an ke leh kekawrte chu leiah an awm a, an hnungzang chu a arch thei a ni. Kut chu an lu chungah a phar thei a, a nih loh leh kut chu hrual theih a ni a, elbow te chu a sir lam hawiin a awm thei a, fist te chu hip hnaih takah a awm thei bawk.
• Mut laiin a thleng tam ber: Hengte hi mut laiin a thleng tam ber. Mahse nilengin an thleng thei bawk. Naupang a harh laiin hetiang hi a thleng a nih chuan naupang chu a tlu thei avangin hliam a awm theihna a awm.
• Hun rei lote chhung: Hei pawh hi second tlemte atanga minute khat vel a ni.

• Atypical absence seizures te hi a awm lo.
• Mit a meng a, a en reng: He seizure-ah hian hriatna a bo a, mahse mit chu a inhawng reng thung. Chuvangin, hei hi nitin mumang, ngaihtuahna fim lo, leh hmun danga awm anga inhriatna anga ngaih sual theih a ni fo.
• Repetitive movements: He seizure chhung hian mit leh hmui chetna i hmu thei. Kut chetna pawh a awm thei bawk.
• Hun rei lote chhung: Hei pawh hi second tlemte aia rei lo a ni.

Pawimawh: LGS vei naupangte hian "clusters"-ah seizures an nei thei a, chu chu hun rei lote chhungin seizure engemaw zat a awm tihna a ni. Naupang hmun thuma ṭhena hmun hnih aia tam"Status Epilepticus" tih hming pu natna a awm thin. Hei hi emergency medical treatment mamawhna condition a ni!

Status Epilepticus tih hi eng nge ni?

Hei hian thil pahnih zinga pakhat a kawk a ni:

• Seizure vawi khat, rei tak minute 5 leh 30 inkar a ni.
• Minute 30 chhungin vawi khat aia tam seizure a awm a, chu seizures chhung chuan chu mi chuan a rilru a hahdam leh tawh lo.

Status epilepticus hi damdawi lam emergency a ni. A hlauhawm zual hle a, a chhan chu thluak a tichhe reng thei a, thihna thlengin a thlen thei a ni.

Symptom dang leh a kaihhnawih seizure chi hrang hrang

• Tonic-clonic seizures: Tonic-clonic seizures (hmanlai chuan "grand mal" tia koh thin) hi tonic seizures ang bawkin a intan a, mahse phase dang a nei thung. Clonic phase hi seizure-a thil langsar ber, taksa chetna (jerks) a lo awm hian a ni. Tonic leh tonic-clonic seizures hi minute hnih vel a ni tlangpui.
• Quick, short, jerky movements: Myoclonic seizures hi a rang, jerky movement a ni. Second tlemte chauh an daih a, mahse a chang chuan a rei zawk thei bawk. Seizure nei lote pawhin hetiang "myoclonic jerks" hi an nei thei bawk. Entirnan, hiccups an siam thei a, mut atanga an harh nghal mai thei bawk.
• Sensory, mental, emaw symptoms dang: Partial emaw focal seizures hian taksa peng tlemte chauh a nghawng a ni.

LGS hi engte nge ni?

Lennox-Gastaut syndrome hi a chhan awm thei engemaw zat a awm. A chhan thenkhat chu nausen pian hmain a awm thin. A dangte chu naupan laia thil thleng vang a ni. ``(LGS)`` hmun li a\anga hmun khat velah chuan a chhan chiang tak hriat theih a ni lo.

A chhan hriat chhuah thenkhat chu hetiang hi a ni:

• Pian hmaa thluak thanna lama harsatna awm.
• Lu hliam na tak (traumatic brain injuries emaw concussions emaw).
• Thluak tichhe thei natna hrik, meningitis emaw encephalitis emaw ang chi te.
• Metabolic natna rochun, entirnan `(Mitochondrial diseases)`.
• Nau piang hma emaw, nau neih lai emawa oxygen tlakchham vanga thluak chhiatna (cerebral hypoxia).
• Tuberous sclerosis natna a ni.
• Thluak natna (brain tumor) a awm.
• West syndrome (hei hi epilepsy chi dang a ni a, a hnuah LGS-ah a lo chang thei).

Zirchiangtute chuan LGS vei zingah "de novo mutations" hi a awm fo tih an hmuchhuak.De novo tih awmzia chu "a tir atang khan" tihna a ni. Chungte chu mi pakhat `(DNA)`-a chhiatna awm, rang taka, random taka lo awmte an ni. Chu chu, mutation hi chu mi siamtu sperm emaw egg emaw `(DNA)`-a chhiatna avanga lo awm a ni a, mahse nu leh pa pahnih zinga pakhat `(DNA)`-a chhiatna a ni lo tihna a ni.

Mahse, he dinhmun hi genetic influence a awm thei a ni. LGS vei zinga 30% vel chu chhungkaw history-ah epilepsy vei an ni. Mahse, hei hi engzat nge genetic factor a nih tih chiang taka hriat theih nan zirchianna tam zawk neih a ngai a ni.

Hei hi hri kai theih a ni em?

Ni lo, Lennox-Gastaut syndrome hi a kai thei lo. Mi pakhat atanga mi dangah a darh lo. Mahse, natna hrik kai thenkhat chuan thluak a tichhe thei a, ``LGS'' a thlen thei bawk. Mahse, chutiang natna vei zawng zawng chuan ``LGS'' an nei vek dawn lo.

Engtin nge Lennox-Gastaut syndrome (LGS) hi hmuhchhuah a nih?

LGS hriat theihna turin test engemaw zat an ti tlangpui a, doctor chuan neurological exam a ti ang. Naupang enkawltu doctor chuan an fate natna lan chhuah dan chungchanga nu leh pate sawi dan a\angin he natna hi a ringhlel thei a, a bik takin naupangin zirlai lama harsatna emaw, nungchang lama harsatna emaw a neih chuan.

Hei hi hriat theih nan eng test nge tih thin?

Test hman tlanglawn ber berte chu:

• Electroencephalogram (EEG): Hei hi thluaka electrical activity tehna tur conductive gel hmanga lu vunah electrode engemaw zat dah a ni. EEG hi LGS hriatchhuahna atan a pawimawh hle a, a chhan chu thluak wave-ah electrical pattern danglam tak a lantir vang a ni.
• Magnetic Resonance Imaging (MRI): Hei hian magnet chak tak leh computer hmangin taksa chhung lam, a bik takin thluak lam hawi resolution sang tak thlalak a la thin. Hei hian thluak thanna lama harsatna awmte hriatchhuahna kawngah a pui hle.
• Lab testing: Heng test-te hian thisen leh zun an enfiah a, seizures awm chhan dang a awm leh awm loh an enfiah thin. Thisen chemistry, liver enzyme, leh kal hnathawh ang chi thil an en thin. Heng test te hian LGS hi chiang takin a hriat theih loh laiin, LGS ang chi natna dangte chu paih chhuah kawngah a pui thei a ni.
• Genetic testing: Hei hian LGS thlen thei inherited condition a awm leh awm loh, a nih loh leh spontaneous mutations a awm leh awm loh hriat theih nan a pui thei a ni.

Chu bakah, test dang pawh tih theih a ni a, chutiang bawk chu a awm lo thei bawk. Hemi chungchang hi i doctor chuan a hrilh belh ang che.

Hei hi engtin nge enkawl theih ang? Dam theih a ni em?

LGS tan hian enkawlna kawng hrang hrang a awm a. Mahse, he natna hi enkawl harsa tia hriat a ni. A tam zawkah chuan heng enkawlna pakhat emaw, a pahnih emaw hi hman theih a ni:

• Damdawi chi hrang hrang
• Dietary therapies te pawh a awm bawk
• Thluak surgery emaw implanted device emaw hmanga tih a ni

Damdawi chi hrang hrang

Lennox-Gastaut syndrome hi damdawi lakah hian a dodal nasa hle fo thin. Chuvang chuan enkawl a har em em a ni. Thil tam takah chuan damdawi tam tak ei a ngai thin. Thil buaithlak dang chu antiseizure damdawi thenkhat, seizure chi hrang hrang control tu hian seizure chi dang a tipung thei a ni.

He natna hi enkawl theih loh a nih chuan doctor-te chuan seizure chi hrang hrang ven an tum thei a, a nih loh leh a awm tam loh pawh an ti tlem thei bawk. Entirnan, atonic seizures hi ven a pawimawh hle a, a chhan chu tlu avanga hliam tuar theihna sang tak nen a inzawm tlat a ni.

Dietary therapies te pawh a awm bawk

Epilepsy na tak nei tam tak tan chuan ei leh in thlak danglam hian seizure awm tam lohna a ti tlem thei a, a titawp vek thei bawk. Epilepsy tan chuan ketogenic diet – protein leh thau tamna leh carbohydrates tlem ei tur – hi doctor-te chuan an rawt fo thin. Damdawiin hna a thawh loh lai pawhin duhthlan tur tha tak a ni thei.

Ketogenic diet hi epilepsy na tak enkawlna lar tak ni mahse, a chhiatna tlemte a nei. He diet hian a dik taka i zawm chauhvin hna a thawk thei. Hei hi a chhan chu carbohydrates tam lutuk, sugar leh starchy foods ei hian seizures a thlen thei a ni. Mahse, modified diet dangte pawhin a pui thei bawk. I duh chuan i doctor chuan heng diet zinga pakhat hi enchhin turin a pui thei che a ni.

Thluak surgery leh implanted devices te

Thil engemaw takah chuan, a bik takin enkawlna dangin a hlawhtlin loh chuan operation hi a tha ber a ni. Surgery chi hrang hrang hetiang hi a ni:

• Vagus Nerve Stimulation (VNS): Hei hian taksaah hmanrua dahin, chu chuan 10th cranial nerve, vagus nerve – thluak nena inzawm tlat, electrical current na lo tak a thlen a ni. He current hian seizure awm tam dan leh a nasat dan a ti tlem thei a ni. Hun a kal zel a, a nghawng chu a pung zel a ni. Hei hian seizure tlem zawk leh seizure na lo zawk tihna a ni. He device hi implant hi reversible procedure a ni a, risk a tlem a, a dam rei pawh a rei lo hle a, chuvangin major surgery hmain ngaihtuah a ni fo thin.
• Corpus callosotomy: Corpus callosum hi thluak peng pakhat a ni a, veilam leh dinglam hemisphere inkar kawngpui (bridge) angin a thawk a ni. Corpus callosum chu tihtawp a nih chuan seizure thlentu signal pangngai lote chu a kal leh zel tawh lo. Hei hian seizures awm tamna a ti tlem thei a, seizures na tak, disabled tak pawh a titawp thei bawk.
• Hemispherectomy `(Hemispherectomy)` tih hi a awm lo.Hei hian thluak sir khat chu surgery hmanga lakchhuah a ngai a ni. Hei hi a lutuk angin a lang thei a, mahse specialist-te chuan thunun theih loh seizures tihtawp nan an hmang thei a ni. A hnuah chuan physical therapy hian thluak chu a danglamna chu a insiamrem theih nan a pui fo thin. Thluak hian a remap leh a, a bak zawng chuan a lakchhuahna hnathawh chu a la ta a ni.
• Resection: Thluak chhunga structure anomalies awm hian a chang chuan LGS a thlen thei. Chutiang thil dik lo chu doctor-te’n an hmuh theih chuan thluak tissue chhia emaw, natna nei emaw chu an paih chhuak thei a, seizures chu an titawp thei a ni. Mahse, LGS-ah chuan seizure activity hi thluak hmun khat aia tam a awm avangin hei hi LGS tan chuan a hlawhtling vak lo tlangpui.

Enkawlna avanga harsatna/side effect awm thei

Enkawlna avanga harsatna awm thei chu enkawlna tinah a bik takin a awm thin. Chuvangin, nangmah emaw, i fain emaw enkawlna i dawn avanga harsatna leh side effect awm thei te chu i doctor nen sawipui a tha ber. Chumi hnuah chuan doctor chuan i dinhmun, i dinhmun leh damdawi lam dinhmun dangte nena inmil thute a pe thei che a ni.

Engtiang chiahin nge enkawl hnuah ka dam leh ang? Eng chen nge a dam leh theih ang?

Enkawlna hnua dam leh hun chhung hi enkawlna hman dan leh i dinhmun pum pui a zirin a inang lo hle. I doctor hi i beisei tur dik tak leh eng chen nge i dam leh theih dawn tih hrilhtu tha ber a ni.

Lennox-Gastaut syndrome (LGS) hi ven theih a ni em?

A tam zawkah chuan LGS hi ven theih a ni lo. Chutiang bawkin, a vei theihna pawh a tlahniam thei lo. A danglamna awm chhun chu LGS avanga lu leh thluaka hliam awm thei venna a ni. Hetiang dinhmun lo thleng tur venna awmchhun chu i fate chu approved, certified helmet vuah tir hi a ni.

Ka fa emaw kei emaw hian hetiang dinhmun hi kan nei a nih chuan eng nge ka beisei ang?

Lennox-Gastaut syndrome hi natna khirh tak a ni tlangpui a, a rah chhuah na tak a ni. Hetiang natna vei naupang tam tak hian zir thiam lohna leh thluak chhiatna nghet tak neiin an rilru lama theihna a tikhawtlai a ni. Tin, atonic seizures (drop attack) hi a awm fo avangin, leh tlu a thlen fo avangin, hetiang natna nei naupangte hi hliam an tuar theihna a sang hle bawk.

Hetiang dinhmun hi enkawl harsa tak a ni bawk. Naupang tam tak chuan anmahni enkawl theih loh avangin dam chhung zawng specialist enkawlna an mamawh a ni. Mahse, he natna vei thenkhat hian thluak chhiatna tenau chauh an nei a, chu chu mahni inrintawkna neiin an nung thei tihna a ni.

(LGS) hi eng chen nge a daih?

Seizures tihtawp vek tura enkawlna pek a nih loh chuan (a tlem hle) LGS hi dam chhung zawnga natna a ni.

Hetiang dinhmun hi eng nge a thlir ang?

Lennox-Gastaut syndrome vei theihna lian ber chu thluak tihchhiat a ni a, chu chu thunun theih loha seizure vang emaw, seizure avanga tlu vang emaw a ni. Chutiang hlauhawmna avang chuan ``LGS'' vei te chu an hmuhchhuah atanga kum 10 chhunga thihpui zat chu 3% leh 7% inkar a ni.

A then phei chuan damdawi lam kalphung hian LGS vanga seizure awmte chu a titawp thei a ni. Hei hian natna chu a titawp a, mahse a hmaa seizure avanga thluak chhiatna chu a siam tha thei lo.

Engtin nge ka in enkawl ang? / Engtin nge ka fa ka enkawl ang?

Nangmah emaw, i hmangaih tak emaw LGS i nei a nih chuan i doctor thupek dik taka zawm a pawimawh hle. Hei hian a huam tel a ni:

• Damdawi pek dan anga ei.
• Doctor hnena a rawt angin kal.
• Seizures enkawl leh seizures thlen thei trigger emaw situation emaw pumpelh.

Engtikah nge Doctor ka hmuh ang?

I emaw i fa emaw doctor chuan a tul angin follow-up visit atan rawn lut turin a hrilh ang che. I seizure symptoms a danglam nasa a nih chuan emaw, nitin nunphung pangngai leh thiltih dan pangngai a nghawng a nih chuan doctor i pan tur a ni bawk.

Engtikah nge Emergency Treatment Unit (ETU) ah ka kal ang ?

Nangmah emaw i fa emaw hian medical emergency status epilepticus tih criteria zawm thei seizure emaw multiple seizures emaw i neih chuan i hnai ber damdawi inah emergency room-ah i kal tur a ni. Hei hian a hnuaia dinhmun hrang hrangah hian a kawk a ni:

• Seizure vawi khat chu minute 5 leh 30 inkar a nih chuan.
• Minute 30 chhunga seizure vawi hnih emaw a aia tam emaw a awm a, seizures lai hian mi chu a hriatna famkim a neih leh loh chuan.

Take-Home Thuchah a ni

Lennox-Gastaut syndrome (LGS) hi epilepsy natna khirh tak, a hmaa lo awm thin a ni. Naupang nunah nghawng thui tak, a chang chuan dam chhung zawng pawh a nei thei fo. Enkawl harsa tak ni mah se, damdawi thar, surgery leh enkawlna te hian natna nasatzia tihziaawmna leh natna darh zel tur tihtlem nan a pui thei a ni. A tlem berah chuan enkawlna hian a natna chu a tidam vek thei a ni. Mahse, he natna hi enkawl theih leh tihdam theih a nih leh nih loh hriat chian nan zirchianna tam zawk neih a ngai a ni. I fa hian heng symptoms zinga pakhat tal a neih chuan a rang thei ang bera doctor pan a tha ber.

` Lennox-Gastaut syndrome, LGS, epilepsy, seizures, naupang enkawlna, thluak lama harsatna, thluak lam natna