Heng mast cell te hi engte nge ni? Hei hi i allergy chhan a ni em?

Leivut tlemte i khawih pawhin i thawk i chhuak tan em? A nih loh leh, rulhut emaw, rulhut emawin a seh i nih chuan, chu hmun chu a sen a, a hring a, tuar theih loh khawpin a hrual bawk em? Mi tam tak chuan hetiang thil tawn hi kan tawng tawh a. Chuvangin, vawiin hian hetiang hun laia kan taksa chhunga lo awm thin he reaction siamtu key player chungchang kan sawi dawn a ni. Chu chu "Mast Cells " a ni.

A awlsam zawngin, heng mast cell te hi tute nge ni?

Mast cells hi i immune system-a sipai bik an ni. Kan ram hian amah vengtu tur sipai a neih ang bawkin kan taksa pawhin a venghimtu tur immune system a nei bawk. Heng mast cell te hi chu system chhunga vengtu an ni a, an inring reng a ni.

Heng cell te hi kan ruhro (bone marrow) ah an lo piang chhuak thin a ni. Chumi hnuah thisen kal tlangin kan taksa tissue hrang hrangah an awm ta a ni. Chutah chuan an hna chu a intan ta a ni. An hna ber chu taksa tana hlauhawm chi hrang hrang laka min humhim hi a ni.

Mahse a chang chuan heng mast cell te hi an thawk nasa lutuk thin. Chutah chuan buaina chu a intan ta a ni. Dust mite emaw ei tur emaw ang chi thil hlauhawm lo tak takah pawh reaction lian tak an siam thei a ni. Heng dinhmunte hi ‘allergies’ emaw ‘allergic asthma’ emaw kan ti thin. Thil na tak tak thenkhatah chuan heng mast cells te hnathawh hian allergic reaction na tak anaphylaxis an tih chu a thlen thei a, chu chuan nunna a tichhe thei a ni.

Engtin nge heng mast cell te hian hna an thawh? He 'alarm system' hi i hrethiam ang u!

I taksa hi kulh lian tak angin ngaihtuah rawh. Mast cells chu chu kulh bang hmun tinah alert system dah ang mai a ni. He alarm system hi pawn lam hmelma, chu chu natna hrik, virus leh bacteria, leh rulhut rulhut leh wasp rulhut ang chi toxins te laka taksa venhim turin a inpeih reng a ni.

Hetiang kalphung hi engtin nge a lo awm tih hi chipchiar deuhin han thlir ila:

1. Hmelma hriatchhuah: Pakhatnaah chuan hrik thar emaw allergen thar emaw i taksaah a luh chuan immune system peng pakhat B-cells an tih chuan a hrechhuak thin.

2. Hriamhrei bik siam: Hmelma an hriat chian hnuah B-cell te hian chu hmelma tan bik antibody chi khat an siam tan thin. Heng antibody te hi immunoglobulin E (IgE) an ti a.

3. Guard-te ralthuam hmanga thuam:Heng siam IgE antibodies te hi kan thawnthua hero te mast cells chung lamah an kal a, an innghat tlat thin. Vengtu hnenah ralthuam pek ang mai a ni.

4. Alarm a ri: Tunah chuan mast cell te chu an IgE ralthuam nen high alert-ah an awm ta. A dawt leha hmelma ang chiah (i.e. hrik emaw allergen ang chiah) taksaah a luh leh hunah chuan mast cell-a IgE inzawm chuan a man ang. Chu chu mast cells te chu ``activated'' an nih lai a ni.

5. Histamine attack: Mast cells te hi activate an nih chuan an chhunga chemical dahkhawm tam tak chu vawi khatah a chhuah tir thin. Heng chemical zinga pawimawh ber chu histamine a ni .

Kan taksaah hian chemical histamine an tih chhuah hian eng nge thleng tih hi han thlir ila.

Tunah chuan allergy kan neih hian taksaah eng nge thleng tih i hrethiam tawh a ni lawm ni? Heng zawng zawng hi min humhimna tura tih ni mah se, a chang chuan he chhanna hi a na lutuk thin.

Taksaah hian khawiah nge heng mast cells te hi an tam ber?

Heng guard-te hi pawn lam atanga hrik leh allergen lo lut tur kawngkhar lian ber berteah an awm tam ber a ni. Chu chu:

• Thâwkna kawng leh lung: Kan thawh chhuah boruak nena lo thleng thil lakah inveng rawh.
• Digestive system (GI tract): Kan ei leh in nena lo kal natna hrik lakah inveng rawh.
• Vun: Vun chunglam atanga thil lutte lakah inveng rawh.
• Heng cell te hi thisen kalna leh nerve vel ah pawh hmuh tur a awm bawk .

Mast cells nena inzawm natna awm thei te chu engte nge ni?

Mast cells a chhiat chuan natna chi hrang hrang a awm thei a. Ṭhenkhat chu a tlanglawn leh hriat hlawh tak tak an ni.

Heng symptoms te hi fimkhur rawh.

Mast cell natna lan chhuah dan chu:

• Vun a sen, a hring, a lum tih hriat.
• Taksa hmun hrang hrangah a hring (edema) a awm.
• Thâwk harsa.
• Allergy na tak (anaphylaxis) a awm thei.

Heng symptoms te hi i tawng fo a nih chuan mahni invenna aiin doctor pan a, thurawn lak a pawimawh hle.

Engtin nge doctor hian heng natnate hi a hriat theih ang? Enkawlnate chu engte nge ni?

I doctor-in i symptoms a zirin mast cell natna i vei nia a rinhlelh chuan test chi hrang hrang a ti thei ang.

• Thisen test a ni
• Zun test a ni
• Allergy vun test a ni
• A châng chuan ruhro emaw vun emaw sample tlem te chu test (`biopsy`) atan lak a ni.

Damlo hrang hrangah leh a dinhmun a zirin enkawlna kawng hrang hrang a inang lo. Enkawlna tlanglawn tak takte chu:

• Allergens laka inthiarfihlim: I allergy i neihte hriatchhuah a, chuta hlat taka awm.
• Damdawi: Symptoms control nana pek thin damdawi. Entirnan, antihistamine leh montelukast te hi a ni.
• Mast cell stabilizers: Heng damdawi te hian mast cell atanga histamine ang chi chemicals chhuak tur chu a titawp a ni.
• Emergency damdawi: Anaphylaxis na tak tan epinephrine ang chi damdawi.

A tawp berah chuan mast cell hi a tha em, a tha lo em ni?

Mi tam zawk chuan mast cell chungchang hi allergy ang chi harsatna an neih hunah chauh an hre thin a, chuvang chuan thil tha lo takah an ngai mai thei. Mahse a nihna takah chuan mast cells hi kan taksa invenna atana thil pawimawh leh pawimawh tak a ni.

A tam zawkah chuan natna leh hrik lakah min venghim thin. Tlem an phur lutuk hian allergy kan nei thin. Rukru tlemte man tumin khaw pum pui halral vengtu thahnemngai lutuk ang maiin.

Chuvangin, a dawt leha i thawk hah emaw, i inhnim emaw hunah heng mast cell te te hi thinlung takin lawmthu sawi rawh. A chhan chu nangmah humhim turin an thawkrim em em a ni!