Thyroid cancer chi khat Medullary Thyroid Cancer (MTC) hi i hria em?

I kawr hmalam a butterfly ang maia thyroid gland awm hi i hre tawh ngei ang. A châng chuan he gland-ah hian lump te tak te i hre thei bawk. A nih loh leh doctor chuan i enfiah laiin a hmu mai thei bawk. He lump hi a hlauhawm lo tlangpui laiin, a tlem berah chuan cancer chhinchhiahna a ni thei. Vawiin hian thyroid gland-a cancer chi khat bik, mahse a tlem berah chuan a awm lo tih kan sawi dawn a ni.

Medullary thyroid cancer (MTC) hi eng nge ni?

A awlsam zawngin sawi ila, Medullary Thyroid Cancer (MTC) hi i thyroid gland chhunga cancer lo awm thin a ni. He gland chhung lam hi ‘medulla’ an ti a. He medulla-ah hian cell chi khat bik a awm a, chu chu ‘parafollicular C cells’ an ti a ni. Heng C cell te hian hormone ‘calcitonin’ an siam chhuak thin. Chuvangin, heng C cell te hi thunun theih loha an lo thang lian tan chuan MTC a lo awm ta a ni. Huan chhunga thing duh loh zawng zawng, thunun theih lohvin hmun tina a darh ang maiin ngaihtuah rawh.

Cancer chungchang i hriat hian zawhna leh hlauhna tam tak neih hi thil pangngai a ni a, a bik takin a chi tlemte a nih chuan. Mahse, he zinkawngah hian i medical team te chu an awmpui reng tih hre reng ang che. MTC enkawl dan chi hrang hrang a awm a.

Medullary thyroid cancer (MTC) hi engtiang chiahin nge a awm?

Tunah chuan, "Aw, hei hi mi zawng zawngin kan vei thin natna a ni em?" Lungngai suh. Thyroid cancer hi a tam tawk hle. Mahse, kan sawi tum chi , medullary thyroid cancer (MTC) , hi a tlem hle . United States ang ramah pawh hian thyroid cancer report zawng zawng zinga 4% atanga 10% chauh hi MTC a ni tih hmuhchhuah a ni. Chumi awmzia chu kum tin chutah chuan mi 1,000 vel chauh MTC vei hmuhchhuah an ni tihna a ni. Chuvangin, Sri Lanka-ah chuan he zat hi a hniam zawk mai thei.

Medullary thyroid cancer (MTC) natna lan chhuah dante chu engte nge ni?

Okay, chuti a nih chuan MTC symptoms te chu engte nge ni? Mi zawng zawng hian symptom inang an nei vek lo. Mahse, a tlangpui thenkhat chu:

• I thyroid gland chunglama lump (nodule) awm chu palpable a ni. Hei hi mi 75% atanga 95% velin an natna an hmuhchhuah huna an lan chhuah dan ber a ni. Lump te tak te ang maiin a lang thei a, a chang chuan i kawr hmalam i en pawhin a lang thei bawk.
• Kawr chhunga lymph node lo hring chhuak . Hei hi natna hmuhchhuah hunah mi 70% vel ah pawh hmuh tur a awm bawk. Chungte chu kawr sir lehlamah hnah te te angin hriat theih a ni.

Mahse, a tlem hle a, thyroid nodule a lian a nih chuan a hnuaia symptoms te hi a awm thei a ni:

• Aw a inthlak a, a ri chhuak.
• Chaw ei harsa.
• Thâwk harsa.

A pawimawh ber chu mi thenkhatin MTC nei mahse hun rei tak chhung chu symptom an lantir lo. Hei hi a chhan chu tumor hi cancer a nih vang a ni.A te hle mai. Chuvangin, i kawr ah thil danglam bik i hmuh chuan ngaihven a pawimawh hle.

Engvangin nge medullary thyroid cancer (MTC) hi a lo awm?

Tunah chuan he MTC hi engvangin nge a lo awm tih hi han en ila. Hei hi chhan hrang hrang a awm a. A bik takin MTC hi kawng hnih a awm a.

Sporadic MTC a awm bawk

MTC vei zinga 75% vel (pali zinga pathum vel) chuan he natna hi an vei fo thin . Chumi awmzia chu an chhungkuaa tumahin MTC an la nei lo tihna a ni. Chhungkaw chanchin nei lovin a thleng thin. Scientist te chuan he MTC sporadic lo awm chhan dik tak hi an la hmuchhuak lo. Mahse, hetianga MTC vei zinga 40% leh 50% inkar hian ``(RET)`` tih gene-ah mutations an nei a ni. Hei hi an pianpui thil a ni lo va, nakin lawka lo piang chhuak genetic abnormality a ni.

MTC hi thlah khat atanga thlah dangah a ni

A lehlamah chuan MTC vei zinga 25% vel (pali zinga pakhat vel) chuan rochun natna ‘Multiple Endocrine Neoplasia type 2’ (MEN2) tih an nei thei bawk. ‘MEN2’ hi subtype engemaw zat a awm a:

• `(MEN2A)`: Hetiang natna vei te hian MTC vei theihna chance a sang hle (90% vel) .
• `(MEN2B)`: `(MEN2B)` case thenkhat chu rochan atanga lo chhuak a ni. Mahse, a tam zawkah chuan chutiang chu a ni lo. `(MEN2B)` vei te hian kum naupang takah MTC vei theihna chance 100% an nei .

He `(MEN2B)` hi subtype dang a awm a, chu chu `Familial Medullary Thyroid Cancer (FMTC) tih a ni. `(FMTC)` vei te hian `(RET)` gene mutation an nei a, mahse MTC chauh an nei (cancer chi dang erawh an nei lo).

Ngaihtuah teh, i chhungkuaa mi pakhatin he ``(RET)`` gene mutation hi a nei tih hmuhchhuah a nih chuan, cancer a lo awm hmaa preventive surgery hmanga thyroid gland lakchhuah tir a, hlauhawm lian tak i pumpelh thei mai thei.

Engtin nge medullary thyroid cancer (MTC) hi hmuhchhuah a nih?

MTC hi thyroid gland-a lump angin a lang hmasa fo thin. Nangmah ngeiin i hre mai thei a, i doctor pawhin routine exam-a i kawr i hriat hian a hmu thei bawk. A châng chuan, chhan dang vanga imaging test an tih laiin a lump hi a thleng mai maiin hmuh a ni ṭhin.

I doctor chuan MTC i vei nia a rinhlelh chuan heng test te hi an order mai thei:

• Imaging test: Hengte hian thyroid nodule chiang taka hmuh theih nan a pui thei a ni. Entirnan , thyroid ultrasound , CT scan , leh/ emaw MRI te.Hetiang test hi i ti thei bawk. Camera hmanga thlalak lak ang bawkin heng machine te hian taksa chhunga thil awmte chu chiang takin an hmu thei a ni.
• Fine needle aspiration (needle biopsy): I doctor chuan i thyroid nodule atanga tissue sample tlemte (biopsy) lak a rawt mai thei. Hei hian needle nalh tak tak hman a huam a ni. Needle prick te tak te ang maiin a lang. He tissue sample hi microscope hmangin cancer cell a awm em tih enfiah a ni.
• Thisen test: Heng zingah hian i thisena thil awm zat tehna test te pawh a tel thei a, chu chu calcitonin leh carcinoembryonic antigen (CEA) te an ni. Heng level te hi MTC vei zingah a sang tlangpui.

I doctor chuan ``MEN2'' tih hming pu genetic condition i neih leh neih loh enfiah turin genetic test neih a rawt thei bawk. Chutiang a nih chuan thisen chhûngkaw dangte tân genetic test neih an rawt mai thei a, chu chuan an hlauhawm em tih hriat nân a ṭanpui thei a ni.

Medullary thyroid cancer (MTC) enkawl dan tur chu engte nge ni?

Okay, tunah chuan MTC tan eng treatment nge awm tih kan en ang.

MTC enkawlna ber chu i thyroid gland zawng zawng lakchhuahna operation (total thyroidectomy) a ni . Hei hi operation lian tak angin lang mahse, he cancer tihdamna kawng tha ber a ni.

• Lymph node lakchhuah: I kawr chhunga lymph node-ah thyroid cancer a darh (metastasized) a nih chuan surgeon pawhin a la chhuak ngei ang.
• Hormone therapy: Operation i neih zawhah i dam chhung zawngin thyroid hormone thlakna damdawi i ei a ngai dawn a ni. Thyroid gland atanga hormone siam chhuah te hi taksa tana pawimawh tak a nih avangin pawn lam atanga pill angin pek a ngai a ni.

Surgery bakah hian i doctor chuan enkawlna dang a rawt thei a, chung zingah chuan:

• Radiation therapy: Energy sang tak nei rays hmanga cancer cell tihchhiat dan a ni.
• Chemotherapy: Damdawi hmanga cancer cell tihhlum dan a ni.
• Targeted therapies: MTC natna thenkhatah chuan DNA inthlak danglamna chauh target tur damdawi bik hman a ni. Entirnan vandetanib leh cabozantinib te hi a ni .

MTC enkawl hnuah i doctor chuan thisen test hmangin i CEA leh Calcitonin level a enfiah fo ang. Hei hian enkawlna a hlawhtlin zia leh cancer chu a lo let leh tawh em tih an hriat theih nan a pui ang.

MTC hi cancer a ni a, thyroid cancer chi dang, a tam zawk aiin a nasat deuh thei a ni. Mahse, a kawng emaw taksa peng dang emawa lymph node-a a darh hmaa hmuh a nih chuan enkawl, tihdam leh thunun a awlsam zawk hle.

Medullary thyroid cancer (MTC) vei tan chuan eng prognosis nge a awm?

MTC vei tan chuan prognosis, a nih loh leh outlook chu thil engemaw zatah a innghat a ni.

• Cancer stage (chu chu cancer hi eng chen nge a darh tawh tihna a ni).
• Cancer hian taksa peng dangah a darh (metastasized) em tih.
• Surgery neih laiin cancer natna hrik awm zat chu engzat nge lakchhuah a nih.
• I kum leh i hriselna zawng zawng.

MTC prognosis hi a tlangpuiin papillary thyroid cancer leh follicular thyroid cancer te angin a tha lo . Mahse, nang leh i doctor hian MTC hi in vei hma chuan operation hmangin a dam vek thei a ni . Diagnosis a tlai a nih pawhin MTC hi a darh zau (a na zual) fo thin .

Hetiang mite tan hian dam leh theihna chance a hniam deuh mai thei:

• Kum 65 chunglamte.
• Cancer vei dinhmun sang zawka awmte.
• Surgery neih laiin cancer chu a chhuak kim thei lo te.

Medullary thyroid cancer (MTC) dam rei zawng hi engzat nge ni ang?

MTC vei damchhuah zat chungchang sawi dawn chuan tuna zirchianna atanga a lan dan chuan MTC stage pakhatna, pahnihna leh pathumna kum nga chhunga damchhuah zat chu 93% vel a ni. Mahse, stage palina atan chuan he rate hi 28%-ah a tlahniam thung.

Mahse, hetah hian thil pawimawh tak chu kum tin MTC vei thar an tlem em avangin heng damchhuah zat hi a dik vak lo mai thei. I medical team chuan i beisei tur chu a hre chiang zawk ang.

Papillary leh medullary thyroid cancer hi eng nge an danglamna?

Tunah chuan, ‘He MTC leh chutiang thyroid cancer chi dangte hi eng nge an danglamna?’ tih hi i ngaihtuah mai thei.

Papillary thyroid cancer hi a tam ber a ni . Thyroid cancer hmuhchhuah zinga 80% vel a ni. Mahse, medullary thyroid cancer (MTC) hi a awm lo .

A danglamna ber chu heng cancer chi hnih lo chhuahna cell-ah hian a awm a ni.

• Papillary thyroid cancer hi i thyroid gland-a follicular cells-ah a intan a, chu chuan thyroglobulin, protein a siam chhuak thin .
• MTC hi thyroid gland-a C cells atanga lo piang chhuak a ni a, chu chuan calcitonin, hormone a siam chhuak thin .

Thil dang pakhat chu papillary thyroid cancer hi radiation exposure nen a inzawm fo a, mahse MTC nen hian chutiang taka inzawmna chiang tak a awm lo.

A tawp berah chuan hei hi hre reng ang che.

Cancer i vei tih hriat chu eng chi pawh ni se, thil hlauhawm tak a ni. Chu chu kan hre vek. Mahse medullary thyroid cancer (MTC) chungchang sawi dawn chuan, a hmaa hmuhchhuah a nih chuan enkawlnaah a chhang tha hle tih hre reng ang che .

MTC vei tam zawk chhan dik tak hriat ni lo mah se, thlahtu natna thenkhat nen hian inzawmna nghet tak a awm a ni. Chuvangin nangmah emaw, i chhungte hnai tak emaw (first-degree relative - nu leh pa, unau, fate) MTC vei nia hriat chuan genetic testing neih a pawimawh hle. Hei hian nang leh i chhungte tan a \angkai hle thei a ni.

MTC vei theihna tur chungchanga zawhna i neih chuan doctor nen inbiakna neih hlau suh. I zawhnate chhang turin an awm reng a ni. A pawimawh ber chu thu hriat reng te, hriat reng te, leh a tul anga hmalak hi a ni.

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