Nangmah emaw i hriat mi emaw hian enzyme tlakchhamna pyruvate kinase tlakchhamna avanga hemolytic anemia i nei em? Hei hi thil awm lo tak a ni. Chutiang hunah chuan i doctor chuan Mitapivat tih pill a pe che a ni mai thei. He hming i hriat hian i rilru a buai deuh mai thei. Chuvangin, vawiin hian he damdawi Mitapivat (brand name PYRUKYND) tih hi awlsam tak leh ngilnei takin kan sawi dawn a ni.
A awlsam zawngin, he Mitapivat hi eng nge ni?
Mitapivat hi damdawi bik a ni a, pyruvate kinase tlakchhamna (pyruvate kinase deficiency) an tih avanga hemolytic anemia enkawlna atana pek thin a ni. Tunah chuan, "Hemolytic anemia hi eng nge ni?"
A awlsam khawp mai. Kan taksaah hian thisen cell chi khat, red blood cells an tih kan nei a. Heng cell te hian kan taksa pum puiah oxygen an phur a. A tlangpuiin heng thisen sen (red blood cells) te hi ni 120 vel an dam thin. Mahse, pyruvate kinase tlakchhamna nei taksaah chuan heng thisen sen (red blood cells) te hi an chhe vek a, tlem a hma deuh, rang zawkin an chhe vek a ni. Chu chu hemolytic anemia an tih chu a ni.
Chuvangin, Mitapivat hian a tih chu thisen sen (red blood cells) rang taka tihchhiat chu a titawp a ni. A dik tak chuan, chu cell-te chu chakna a pe a, an dam rei zawng a tipung bawk . Hei hian eng nge a tih?
- Taksaah thisen sen (red blood cells) a pung zel a.
- Anemia symptoms, hahna, hah fo , leh thawk hah lutuk te chu a tlahniam thin.
- Thisen pek fo ngaina pawh a tlem phah hle.
Chu chu he damdawi hian i nunphung a tisang dawn tihna a ni .
He damdawi hi i ei hmaa i doctor hnena i hrilh tur thilte
Damdawi eng pawh i hman hmain doctor hnenah i hriselna dinhmun kimchang taka sawi hmasak a pawimawh hle. Mitapivat i ei tan hmain a hnuaia natna te hi i neih chuan doctor hnenah hrilh hmasa phawt ang che:
- Liver disease: Liver natna awm tawh i neih chuan min hrilh dawn nia.
- Allergy nei te : 1.1.Mitapivat, damdawi dang, ei tur, dye, emaw, preservatives dang emaw allergy i neih chuan min hriattir ngei ang che.
- Naupai : Naupai emaw, naupai thuai tum emaw i nih chuan i doctor nen inbia ang che.
- Nu hnute petu i nih chuan: Nu hnute petu i nih chuan Doctor hnenah pawh i hrilh tur a ni.
Heng thute a\ang hian i doctor chuan he damdawi hi i tan a tha em tih emaw, a dose thlak a ngai em tih emaw a rel ang.
Damdawi hi engtin nge dik taka hman ang?
Damdawi pakhat atanga hlawkna tam ber hmu tur chuan a hman dik a pawimawh hle.
- He damdawi hi pill i ei thin a ni. Try to take it at the same time every day , i doctor-in a tih ang chiah khan.
- Tablet chu tui nen a pumin ei rawh. Tablet chu tichhia ngai suh, tikehsawm ngai suh, chew ngai suh.
- I doctor-in chawlhsan tura a tih hma loh chuan he damdawi hi ei chhunzawm zel ang che. I rilru a hahdam pawhin chawlhsan thut suh.
- He damdawi hi naupangte hnena pek a nih chuan fimkhur bik a ngai mai thei. Chuvang chuan Doctor thupek ang zelin zawm tur a ni.
Damdawi i ei tam lutuk chuan engtin nge i tih ang? (A tam lutuk) .
He damdawi hi a dose pek aia tam i ei palh ang tih han ngaihtuah teh. Chutiang a nih chuan tihkhawtlai suh. Damdawi in hnai ber Emergency Treatment Unit (ETU) ah kal nghal rawh. A nih loh leh Colombo National Hospital-a National Poisons Information Center-ah thurawn dil turin phone la.
He damdawi hi i tan chauh pek a ni. Mi dang hnenah share ngai suh, i symptoms ang chiah nei mahse.
Damdawi dose khat ka ei loh chuan engtin nge ni ang?
Nun buai lutuk hian a chang chuan damdawi dose khat pawh i hloh mai thei. Chutiang a nih chuan tih tur chu hetiang hi a ni:
- I hriatreng veleh i damdawi ei nghal rawh.
- Mahse, darkar 4 aia tam dose i miss chuan chu dose chu skip vek rawh. I dose lo awm tur chu a hun ruatah ei rawh.
- Eng thil vang pawha dose hloh tawh chu tihpun nan double dose ei suh.
He damdawi nena inzawm thei damdawi dang
Damdawi i ei thenkhat chu Mitapivat nen a inzawm thei. Hei hian Mitapivat hnathawh dan a tidanglam thei a, side effect a tipung thei bawk. Chuvangin, i damdawi ei zawng zawng (vitamin, herbal remedies, leh doctor dangin damdawi an pek te pawh telin) i doctor hnenah hrilh ngei ang che.I doctor hnenah hrilh rawh.
A hnuaia tarlan te hi Mitapivat nena inzawm thei damdawi thenkhat an ni.
| Ruihhlo chi hrang hrang | Entirnan |
|---|---|
| Fungal infection damdawi thenkhat | Fluconazole, Itraconazole, Ketoconazole te a awm bawk |
| Efavirenz (HIV damdawi) 1.1. | Efavirenz chuan a rawn ti a |
| Estrogen leh progestin hormone te hi a ni | Naupai venna damdawi, hormone therapy hmanga enkawlna |
| Midazolam a ni | Damdawi tihlum emaw, tihlum emaw nana hman thin |
| Rifampin a ni | Tuberculosis ang chi natna hrik tan antibiotic pek thin a ni |
Pawimawh: He list hi a kimchang lo hle. Zu i in emaw, zu i in emaw, ruihhlo dang i hman emaw chuan doctor hnenah hrilh rawh.
Damdawi ei huna fimkhur tur thil
He damdawi i ei lai hian i doctor chuan i hriselna a enfiah fo ang.
- Clinic appointment ruat saah tel thin ang che. Hei hi i awm dan leh damdawi hian hna a thawk em tih hriat nan a pawimawh hle.
- I natna lan chhuah dan a tha lo a nih chuan, a zual deuh chuan doctor hnenah hrilh rawh.
- He damdawi hi i ei lai hian thisen hnathawh tir turin an ti mai thei che. Heng test te hi skip suh la, tih fo thin ang che.
Side effect awm thei te chu engte nge ni?
Damdawi zawng zawng ang bawkin Mitapivat hian side effect a nei thei a, mi zawng zawngin an vei vek lo nachungin. Side effect thenkhat chu a pawi thei hle a, chuvangin fimkhur a pawimawh hle.
| Side effect a awm thei | Hrilhfiahna |
|---|---|
| Side effects te chu doctor hnenah hriattir nghal tur a ni | |
| Allergy natna a awm thei | Vun vun rawng, hnim hring, hmai, hmui, lei emaw kawr emaw a hring, thawk harsa. |
| Hemolytic anemia natna a zual zel | A tlangpui aia chau/chau zawka inhriatna, luak chhuak, lu na, thawk harsa, zun dum, vun emaw mit sen emaw. |
| Liver hliam chhinchhiahna | Pum dinglam chunglam na, chaw ei chak lohna, luak chhuak, tarry stools, dark yellow emaw brown urine, vun emaw mit emaw yellowing, chak lohna danglam tak. |
| A awm reng emaw, a buaithlak emaw chuan doctor hnenah hrilh rawh. | |
| Hnung lam natna | |
| Joint natna | |
He list-ah hian side effect awm thei zawng zawng a tel lo. Symptom dang, danglam tak i neih chuan i doctor nen sawiho rawh.
Damdawi hi engtin nge him taka kan dahkhawm ang?
- Naupang leh ran vulhte hmuh theih lohna hmunah dah rawh .
- Room temperature (20 leh 25 degree Celsius inkar) ah dah tur a ni.
- Damdawi chu a dawnna original container-ah dah tur a ni.
- Damdawi expired hmang ngai suh . Hrisel takin paih chhuak rawh.
Damdawi expired emaw, duh loh emaw i paih chhuah dawnin doctor rawn la a tha ber. Bawlhhlawhah paih mai a tha ber mai thei. Chutiang a nih chuan, pill chu bottle atang chuan la chhuakin, coffee ground hman tawh, lei, emaw, ui bawlhhlawh ang chi thil nen chawhpawlh la, bag khar nghet takah dah la, bawlhhlawh bawmah paih rawh.
Take-Home Thuchah a ni
- Mitapivat hi damdawi bik a ni a, pyruvate kinase tlakchham vanga hemolytic anemia a enkawl a ni.
- He damdawi hi doctor-in a tih ang chiah chiah, a hun takah ei fo ang che. Tablet te hi tichhia suh, tikehsawm suh, chew suh.
- I doctor hnenah damdawi dang zawng zawng, vitamin leh damdawi dang i ei zawng zawngte chu kimchang takin pe rawh.
- Side effect na tak tak, allergy emaw, liver chhiatna chhinchhiahna emaw i neih chuan doctor pan nghal rawh.
- He damdawi hi i tan chauh pek a ni. Midang hnenah share ngai suh.
- He damdawi chungchangah hian ngaihtuahna i neih chuan i doctor nen inbia ang che.
💬 Comments (0)
Comment a la awm lo. Hetah hian i comment hi a vawikhatna atan add rawh.
I comment kha add rawh