I chau tawh em? I mit a rit em? Myasthenia gravis chungchang hi i zir dawn teh ang.

Zing lamah tha takin i harh a, mahse ni a liam zel chuan chakna nei lo ang maiin i inhria em? I taksa ruhte a chak lo lutuk a, engmah ti thei lo ang mai a ni a, a bik takin i mit a rit a, tawng i harsat emaw, ei tur i ei harsa emaw? Chutiang thil i tawn tawh chuan tunlaia kan sawi mek natna ‘Myasthenia Gravis’ tih hi i hriat chian a pawimawh hle. Hei hi hriat loh deuh mahse, i hriatthiam awlsam chuan zawhna tam tak chhanna i hmu thei ang.

A awlsam zawngin, Myasthenia Gravis chu eng nge ni?

Myasthenia gravis, a tawi zawngin MG tih hi autoimmune condition a ni . A awlsam zawngin kan taksa invenna system, immune system-in kan taksa peng hrang hrang a rawn beih sual hian a ni. MG ah chuan immune system hian kan nerve leh muscle inzawmna te chu a bei thin.

Hei hian kan ruh nena inzawm leh min chêttîrtu ruhte chu zawi zawiin a tichak lo a ni. Hei hian a nghawng ber chu:

• I mit, i hmai, i kawng, i kut leh ke ruh te tan.

He chak lohna hian hetiang thil hi a ti harsa thei che a ni:

• I mit chu sawn kual la, mit khap rawh.
• I mit kha meng reng rawh.
• I hmai hmangin rilru natna hrang hrang sawi rawh.
• Chaw ei la, ei la, thusawi rawh.
• I kut phar la, i thilte kha han chawi sang rawh.
• Stairs pakhatah chuan chho la, chair atang chuan tho rawh.

Hei hi natna khirh tak a ni. Hei hian damdawi pakhat chauh a awm lo tihna a ni. Mahse, lungngai suh, tunlaia enkawlna tha tak tak hmang hian tu pawhin an natna lan chhuah dan chu an enkawl thei a, nun hrisel takin an hmang thei a ni.

Myasthenia gravis chi hrang hrang a awm em?

Ni e, he natna hi chi hrang hrang lian tak tak a awm. Eng nge an nih i en ang u.

Autoimmune myasthenia gravis natna tlanglawn ber chu chi hnih ah then leh a ni.

Mit lam Myasthenia a awm

Hei hi mit leh mitmeng tichhe thei ruh chauh a chak lo tihna a ni. Hei hian i mitmeng a ti tla thei a, i mit a tivar harsa thei bawk. Mi thenkhat chuan double vision an nei thei bawk. He mit chak lohna hi MG chhinchhiahna hmasa ber a ni fo thin. Hetiang natna vei zinga a chanve vel chuan a tawpah chuan generalized vision an nei ang.

Myasthenia natna tlangpui (generalized Myasthenia) a ni

Hetiang dinhmunah hian mit ruh bakah hian hmai, kawr, kut, ke leh kawr ruh te pawh a chak lo hle. Hei hian thusawi a ti harsa thei a, chaw ei a ti harsa thei a, i kut chu i lu chungah a chawi sang thei a, ṭhutna aṭanga tho chhuakin, hla tak takah kal a, stairs-ah a chho thei bawk.

Engtin nge he natna hi a lo awm tak tak? Kan taksa chhungah eng thil nge thleng?

Hei hi hrethiam tur chuan entirnan tlem han la ila. Kan nerve leh muscle inzawmna hi cricket match-a pitcher leh catcher inkar ang kha a ni ang tih han ngaihtuah teh.

1. The bowler (nerve): Nerve hi taksa peng (muscle) hnena "contract" tura thuchah thawntu a ni.

2. Ball (Acetylcholine): He thuchah hi chemical (neurotransmitter) ‘acetylcholine’ an tih hmanga thawn a ni. Hei hi kan 'ball' a ni.

3. Fielder kutkawr (receptors): He ‘ball’ man nan hian kutphah chungah hmun bik a awm a. ‘Receptor’ kan ti thin. Hei hi fielder 'glove' ang a ni.

A tlangpuiin nerve atanga ‘ball’ (acetylcholine) rawn thawn chu taksa peng chhunga ‘glove’ (receptor) nen a inmil a ni. Chu chu muscle hian contract tur signal a dawng ta a ni. Hei hi a thleng rang hle a, engmah tihbuai lohvin a thleng thin.

Mahse, myasthenia gravis vei taksaah thil danglam tak a thleng thin.

An immune system hian antibody dik lo a siam a, muscle chhunga receptor te chu a block emaw a tichhia emaw a ni. Tichuan, nerve hian ball chu thawn mahse, man tur glove a awm lo. Chuvangin, muscle hian signal dik tak a hmu lo va, chuvang chuan a chak lo hle. I thawhrim chuan ball a man theih loh avangin taksa ruh chu a chak lo lehzual thin. I chawlh hunah chuan glove hi tlem tal i hmang leh thei a, chuvang chuan a nung leh thin. I hrethiam em?

Myasthenia gravis natna lan chhuahna ber berte chu engte nge ni?

MG symptoms hi a intan nghal thei. Nitin leh a hun hunah an intensity pawh a inang lo thei bawk. Mi tam tak chuan ni tir lamah chak zawkin an inhria a, ni tawp lamah chuan chak lo zawkin an inhria.

Engtin nge doctor hian he natna hi a hriat chian tak tak?

Heng symptoms te hi i neih chuan i doctor chuan i medical history a zawt hmasa ang che a, physical exam a ti ang che. Chumi hnuah chuan diagnosis finfiah nan test engemaw zat an order thei ang:

• Thisen test: I thisenah hian a hmaa kan sawi tawh antibodies pangngai lo (`acetylcholine receptor antibodies` emaw `MuSK antibodies`) te chu enfiah a ni ang. MG vei zinga 85% vel chuan an thisenah heng antibodies te hi an nei a ni.
• Imaging scans: I thymus gland-a harsatna emaw, tumor (thymoma) emaw a awm leh awm loh enfiah nan CT emaw MRI scan emaw tih theih a ni.
• Electromyography (EMG): Hei hi test specialized deuh a ni a, nerve leh muscle inkara electrical signal kal danah thil dik lo awm apiang a zawng thin.

Heng test result a\ang hian i doctor chuan i dinhmun stage a ruat ang a, i tana enkawlna tur ruahmanna \ha ber a rawn rawt ang che.

Hei hi eng enkawlna nge ni?

A hmasa berah chuan MG hi enkawl theih a ni. Damdawi a awm loh laiin, tûn laiah hian i natna lan chhuah dân enkawltu leh nun pangngai, active taka nunpui thei tûr damdawi ṭha tam tak a awm a ni.

Enkawl dan hrang hrang a awm a:

• Damdawi hman tur: 1.1.
• Damdawi `cholinesterase inhibitors` ang chi hian nerve leh muscle inkara signal transmission a tichak a, muscle chakna a tipung a ni.
• Immunosuppressant, corticosteroids te hian chutiang antibody pangngai lo siam chhuah chu a ti tlem a ni.
• Monoclonal antibody te hi a awm a:Hengte hi protein bik, thisen kal tlanga pek thin an ni. Immune system hnathawh dan an control a ni.
• Plasma exchange (Plasmapheresis): Hei hian i thisen plasma portion antibodies tha lo tak tak awmna chu la chhuakin plasma hrisel emaw solution emaw hmanga thlak thei tur machine bik nena inzawm tir che a ni.
• IV immunoglobulin (IVIG): Donor hrisel tak takte hnen atanga antibodies thisen chhunga infusion a ni. Hei hian immune system a titawp thei a ni.
• Surgery: Mi thenkhat tan, a bik takin thymus tumor nei tan chuan gland chu surgery hmanga lakchhuah a ni (a `thymectomy`). Hei hian symptoms nasa takin a control thei a ni.

I doctor chuan i dinhmun atana enkawlna tha ber a thlang ang.

Symptoms nena kan nun lai hian keimahni tan eng nge kan tih theih ang?

Enkawlna i dawn lai hian i nunphungah inthlak danglamna tenau te siam hian he natna nen hian nun a ti awlsam thei hle.

• Exercise: I doctor zawt la, i tana ṭha tur exercise light tak ti rawh . Hei hian i taksa ruh a tichak ang a, i rilru a ti hahdam ang a, chakna a pe bawk ang che.
• Khua lum loh tur: Khua lum lutuk hian natna lan chhuahna a ti na zual thei. Chuvangin ni lum takah chuan chhuah loh tur a ni. I lum nia i hriat chuan i kawr leh i hmaiah puan tui lum a hnim hrual chu dah la.
• Ei leh in tha: chakna i neih theih nan protein leh carbohydrates tamna ei leh in inthlau tak ei thin ang che.
• I hnathawh tur ruahman rawh: Thawhrimna i neih tam ber laiin thawhrimna mamawh ber hnate chu thawk la, chu chu zing lamah tihna a ni.
• Chawlh hahdam a pawimawh: Nitin chawlh rei vak lo la. Mut hahdam rawh. I taksa chu ngaithla rawh. I chau nia i hriat laiin hna thawk turin in nawr luih suh.