Cancer hmuh tur awm lo, Sarcomatoid Carcinoma tih hi i hria em? Chipchiar takin sawi ila!

Cancer hian min ti hlauhawm deuh vek a ni lawm ni? Mahse cancer zawng zawng hi a inang vek lo. Vawiin hian cancer chi khat hmuh tur awm lo leh buaithlak tak kan sawi dawn a ni. Sarcomotoid Carcinoma an ti a. A hming hi i tan chuan mak tak angin a lang thei a, mahse awlsam taka sawifiah i tum ang u. Doctor-te chuan hei hi cancer chi khat, a lo thang chak hle a, a na hle niin an sawi .

Sarcomotoid Carcinoma chu eng nge ni?

A awlsam zawngin sawi ila, Sarcomatoid Carcinoma hi cancer chi hnih inzawmkhawm a ni. Chu chu carcinoma leh sarcoma pahnih ziarang a nei tihna a ni. Tunah chuan carcinoma leh sarcoma hi eng nge a nih kan en ang.

• Carcinoma: Hei hi cancer chi khat zingah chuan a tam ber a ni. Kan taksa peng emaw vun emaw chunglam khuh tu tissue atang hian a intan thin. Heng tissue te hi epithelial tissue kan tih chhan chu epithelial cell atanga siam an nih vang a ni.
• Sarcoma: Hei hi carcinoma aiin a tam lo zawk. Sarcomas hi ruh, connective tissue (e.g., cartilage, tendons), leh soft tissue (e.g., muscle, thau, nerves) ang chi hmunah te a intan thin. Cell chi khat mesenchymal cell an tih atanga siam an ni.

Chuvangin, sarcomatoid carcinoma-ah chuan, carcinoma leh sarcoma pahnih nena inzawm cell leh tissue awmna tumor chu a lo piang ta a ni. Heng tumor te hi an thang chak hle a, taksa peng hrang hrangah an darh (metastasize) thei a ni. Hei hi a darh chuan taksa chhunga tissue hrisel tak takte chu a chhe vek a ni.

Taksa chungah khawiah nge hetiang hi a thleng tam ber?

Sarcomatoid carcinoma tih hming i hriat hian i lung nen i inzawm tir mai thei . Mahse, he cancer chi hi carcinoma leh sarcoma te ang chi hi taksa peng dangah pawh a awm thei a ni. Entir nan:

• Vun
• Ruh
• Ka
• Thyroid gland a ni
• Hnute
• Pumpui
• Intestine te tak te
• Thin
• Pancreas a ni
• Nausen pum (uterus) a ni
• Prostate a ni
• Bladder a ni
• Kidney a ni
• Chhung lai takah hmun (hei hi ``Mediastinum'' an ti a. Thinlung, thawkna kawng, leh thymus gland ang chi thil hi hetah hian a awm)

Sarcomatoid carcinoma, lung atanga intan hi a darh chak hle niin an sawi. Chutiang chuan hmun engemaw zatah vawi khatah a darh thei a, chungte chu adrenal glands, thluak, ruh, thin, kal, peritoneum, pancreas, vun leh thinlungah te a darh thei a ni.

Hei pawh hi chi hrang hrang a awm em?

Ni e, World Health Organization (WHO) chuan kum 2015 khan sarcomatoid carcinoma chu chi pangaah a then a, heng chi hrang hrangte hi "poorly differentiated non-small cell lung carcinoma" an ti a ni. "Poorly differentiated" tih hian cell te hi a danglam bik em em a, eng chi nge an nih tih chiang taka sawi a harsa tihna a ni. Non-small cell lung cancer hi lung cancer chi khat, a lo thang lian a, a darh chak hle.

Heng chi pangate hi:

• Pleomorphic carcinomas: Hengte hian carcinoma feature an nei tam ber. Mahse, a tlem berah 10% chuan sarcoma feature an nei tlangpui. Hei hi sarcomotoid carcinoma chi khat zingah chuan a tam ber a ni.
• Spindle-cell carcinoma: He cancer chi hi a hming hi microscope hmanga a cell awm dan atanga lak a ni. An sei a, an sei a, spinning wheel-a spindle ang mai an ni.
• Giant cell carcinoma: Hei hian cell lian tak tak, sarcomas ang chi pattern-a inrem a nei a. Chungte chu lung chunglam lamah a lo awm tlangpui.
• Carcinosarcoma: Hei hian carcinoma chi thenkhat atanga tissue te a huam a, chu chu adenocarcinoma leh squamous cell carcinoma te hi a ni. Tin, sarcoma tissue pangngai lo, lo thang chak lo tak takte pawh a huam tel bawk.
• Pulmonary blastoma: Hei hi adenocarcinoma chi khat a ni a, nausen lung tissue ang chi a ni. Mesenchymal cell (sarcomas ang chi) pawh hmuh tur a awm bawk.

Hetiang hi tuin nge nei tam zawk?

Sarcomotoid Carcinoma hi mipa ah a tam ber a . Tuna zuk leh hmuam hmang tawh emaw tun hmaa hmang tawh emaw zingah a tam hle . Diagnosis kum zat chu kum 65 vel a ni.

Hei hi engtiang chiahin nge a hluar?

Hei hi cancer chi khat hmuh tur awm lo tak a ni . Sarcomotoid Carcinoma hi lung cancer zawng zawng zingah hian a tlem hle a, 0.1% leh 0.4% inkar a ni.

Hei hi eng symptoms nge ni?

I natna lan chhuah dan chu i taksaa cancer a darh danah a innghat a ni. Sarcomatoid carcinoma of the lungs i neih chuan hetiang hian symptoms i nei thei ang:

• Khuh (a awm reng) .
• Thâwk harsa (dyspnea) .
• A rilru a na
• Thisen chhuah leh mucus
• Chhan awm lovin taksa rihna tihtlem

Engvangin nge hetiang thil hi a lo thlen?

Doctor-te chuan sarcomotoid carcinoma thlentu lian ber chu "Epithelial-Mesenchymal Transition (EMT)" tih a ni an ti. A awlsam zawngin, hei hi non-small cell lung carcinoma-a cancerous epithelial cells te an inthlak a, thenkhat chu mesenchymal cells ah an inthlak thin a ni. Hetianga cancer cell danglam tak takte hi taksa pum puiah an darh chak hle a ni.

Heng cell inthlak danglamna leh a lo thang chak lutuk te hi cell chhunga genetic mutations nen a inzawm fo thin . I hria em, kan genes hi cell-te awm dan tur hrilhtu a ni. Genetic mutation chu chutiang thupek tihdanglam emaw, tihsual emaw a ni. Scientist-te chuan sarcomatoid carcinoma nena inzawm genetic mutations engemaw zat an hmuchhuak a.

Hei hi eng risk factors nge a nghawng?

Risk factor chu natna vei theihna tipungtu thil a ni. Sarcomotoid carcinoma-ah chuan meizuk hi a hlauhawm ber leh hriat lar ber a ni. Hriat tur pawimawh tak chu he lung cancer vei zinga 80% leh 90% inkar hi tuna zu in tawh emaw, zu in tawh emaw an ni.

Meizial zuk bânsan hian lung natna tam tak lakah a veng thei che tih theihnghilh suh, he natna ang cancer pawh hi a ni.

Engtin nge doctor hian hei hi a hriat theih?

I doctor chuan a enfiah hmasa ang che a, a tul chuan imaging procedure thenkhat a ti ang. Mahse, hei hi sarcomatoid carcinoma a nih leh nih loh hriat chian nan chuan cancer cells te enfiah nan biopsy lak a ngai a ni.

• Imaging: Doctor chuan CT scan hmangin cancer awmna hmun a en thei ang. Taksa chhung lam chiang zawka hmuh theih nan CT/PET scan emaw F-fluorodeoxyglucose (FDG)-PET scan emaw tih theih a ni. CT/PET scan hian test pahnih (CT leh PET) chu a rualin a inzawm khawm a. Fluorodeoxyglucose hi PET scan laiin taksaah a inject a ni. Cancer cell vel a khawlkhawm a, scan-ah a langsar zawk.

• Histopathology: Histopathology chu biopsy atanga cancer tissue sample lak atanga microscopic hmanga enfiah a ni. Cell awm dan hian doctor chu sarcomatoid carcinoma a nih leh nih loh leh, a nih chuan eng subtype nge a nih (e.g., pleomorphic carcinoma, spindle cell carcinoma) tih a hriat theih nan a pui thei a ni.

• Immunohistochemistry hmanga enkawl dan: 1.1.He test hian cell chi hrang hrang nena inzawm antigens an tih thilte a zawng thin. Antigen thenkhat chuan cell pakhat chu a pangngai lo emaw, malignant emaw a nih thu a hriat theih.

Engtin nge enkawl a nih?

He cancer enkawlna tha ber chu surgery hmanga tumor pumpui lakchhuah hi a ni. Chemotherapy hian operation hnua cancer cell la awm zawng zawng a tihlum thei a ni. Mahse, a tam zawkah chuan cancer hi a hriat chhuah hun chuan a darh tawh avangin operation tih theih a ni lo mai thei. Natna, thisen chhuah, thawk harsa tih ang chi harsatna a awm chuan radiation therapy pawh pek theih a ni.

Sarcomatoid carcinoma-ah chuan clinical trial hi enkawlna tha ber a ni thei. Clinical trial chu enkawlna thar a him leh him loh enfiahna a ni. Tunah hian scientist-te chuan he cancer natna i dam rei theihna tur damdawi an zirchiang mek a ni. Chung zinga pahnih chu:

• Targeted therapy: Hei hian cancer cells te chu thunun theih loha an pung zelna tur characteristic bikte target a ni.
• Immunotherapy: Hei hian i immune system a tichak a, cancer cells zawng chhuakin a tichhe thei a ni.

A hlauhawmna tihziaawmna turin eng nge kan tih theih ang?

Zuk leh hmuam hman loh i thlan hian sarcomatoid carcinoma i vei theihna a ti tlem thei a , chubakah lung cancer dang tam tak i vei theihna a ti tlem thei bawk. Hei hi i hmalakna pawimawh ber a ni.

Hei hi a dam kim thei ang em?

Dik tak chuan sarcomatoid carcinoma hi cancer chi khat a ni a, a tlangpuiin tihdam kim harsa tak a ni. Mahse, scientist-te chuan heng tumor-te cellular characteristic, genetic mutations ang chi an hriat belh zel chuan, anmahni target-a enkawlna thar an siam thei ta a ni. He natna hi i vei tih hmuhchhuah a nih chuan enkawlna thar test-na clinical trial-ah i tel thei ang. Hemi chungchang hi doctor zawt rawh.

He natna nen hian eng chen nge i dam chhung?

Hetiang dinhmunah hian eng chen nge i dam dawn tih sawi a har a, mahse fimkhur a pawimawh. A vaiin dam rei zawng hi thla 10 vel a ni. Kum nga chhunga damchhuah zat hi 15% vel a ni. Mahse, heng statistics te hi mi zawng zawngah a inang vek lo. I dinhmun tichhe thei thil tam tak a awm a:

• Cancer-a cell chi khat bik.
• Gene mutations lo awm tawhte chu engte nge ni?
• Natna lan chhuah tirh atanga natna hmuhchhuah thlengin eng chen nge a rei.
• Cancer hian eng chen nge a lo thang lian a, tissue hrisel tak tak a tihchhiat.
• Eng chen nge cancer hi a darh tawh.
• Doctor chuan cancer natna chu a paih chhuak vek thei em tih.

Chuvangin, i dinhmun dik zawka i hriat theih nan heng zawng zawng hi i doctor nen zalen taka sawipui a pawimawh hle.

Doctor hnena zawh tur pawimawhte chu engte nge ni?

Sarcomatoid carcinoma i vei tih i hriat chuan heng cancer te hi chi hrang hrang leh complex tak an nih avangin i lungkham hle mai thei a, i buai hle bawk. I enkawl dan tur leh nakin lawka natna lo awm dan tur chungchangah doctor nen zalen taka inbiakna neih a pawimawh hle. I doctor chuan i cancer cells awm dan leh i taksa chhunga cancer awmna hmun a zirin eng nge i beisei tur tih a hrilhfiah thei che a ni.

Doctor i zawh theih tur zawhna thenkhat chu hetiang hi a ni:

• Ka cancer hi a darh tawh em?
• Ka cancer hi engtiang chiahin nge a nat?
• Eng ang enkawlna nge i rawt?
• Enkawlna atang hian eng side effect nge beisei tur?
• Damdawi lam ngaihdan pahnihna lak hi ka tan chuan thil tha tak niin i hria em?
• Palliative care specialist te nen kan thawh dun a ngai em?
• Clinical trial-ah hian ka tel thei em?

I doctor chuan i mamawh information a pe thei che a, i tlin chuan clinical trial-ah a refer thei che a, palliative care i hmuh theih nan a pui thei bawk che a ni.

Kan hriat reng tur thilte

Okay, chuti a nih chuan, Sarcomatoid Carcinoma chungchang kan sawi tawh atang chuan, hriat reng tur pawimawh tak tak te chu hetiang hi a ni:

• Hei hi cancer chi khat, a nasat em em, a darh chak em em a ni.
• Hei hian carcinoma leh sarcoma pahnih features a lantir a ni.
• Hei hi meizuk hi a hlauhawm ber a ni.
• A lan chhuah dan chu cancer awmna hmunah a innghat. Lung lamah chuan a lan chhuah dan chu khuh leh thawk harsa te a ni thei.
• Hriat chian nan hian test bik (biopsy, imaging) neih a ngai a ni.
• Enkawl dan tur chu a buaithlak hle. Surgery, chemotherapy, leh radiation therapy bakah hian enkawlna thar (targeted therapies, immunotherapy) te pawh ngaihtuah mek a ni.
• Dam vek theihna chance chu tlem hle mah se, zirchianna thar chuan beiseina a pe a ni.
• I dinhmun chungchang hi doctor nen zalen taka sawipui a, engkim chiang taka hriat chhuah a pawimawh hle.

He thu hi in tan a tangkai ngei ka beisei. Hemi chungchangah hian zawhna dang i neih chuan doctor rawn la.

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