Asthma na tak control theihna beiseina thar: Tezspire chungchanga hriat tur

Asthma na tak i nei em? I inhaler leh damdawi dang hmang chung pawhin attack i la nei fo em? Zana mut that loh leh hna tenau ber pawh thawk thei lova i chau em? Chutianga thunun harsa, natna khirh tak neia nun chu a harsat zia chu a tuarte chauhvin an hria. Mahse hlau suh, medical science hmasawnna avang hian tunah chuan enkawlna thar a lo chhuak ta a ni. Vawiin hian chutiang enkawlna thar leh hmasawn tak pakhat chu kan sawi dawn a ni. Chu chu Tezspire a ni.

Engtin nge he damdawi Tezspire an tih hian hna a thawh tak tak?

Okay, asthma kan neih hian kan taksaah eng nge thleng tih hi thu awlsam takin i hrethiam hmasa ang u. Asthma hi kan thawkna kawng, a nih loh leh thlipui (windpipes) te chu a lo hring chhuak a, a hring chhuak a, a sensitive a ni. Allergy thil (entir nan, leivut, meikhu) taksaa a luh chuan heng thawkna kawngte hi a zim a, thawk a harsa thin.

A tlangpuiin, asthma enkawlna atan hian damdawi chi hnih kan hmang thin. Pakhat chu controller damdawi a ni . Hengte hi nitin asthma control nan leh attack laka inven nan hman thin a ni. A chi dang chu chhanchhuahna damdawi a ni . Hengte hi Asthma attack a awm chuan symptoms tihziaawmna atan hman a ni.

Tezspire hi controller damdawi i ei tawhnaah add-on medication a ni. Asthma attack venna atan a pui a, i neih huna ei tur ‘chhanchhuahna’ damdawi a ni lo.

A awlsam zawngin Tezspire hi protein chi khat atanga siam damdawi a ni. A dik tak chuan hei hi (monoclonal antibody) an ti a. Kan taksa hian chemical pakhat (Thymic Stromal Lymphopoietin - TSLP) tih a nei a. He TSLP hi thawkna kawnga swelling (inflammation) leh a tul lo taka sensitivity thlentu ber a ni. Tezspire damdawi hian chu chemical TSLP an tih hnathawh chu a tikhawlo a ni. TSLP hi block a nih chuan thawkna kawng a hring leh a zim te a tlahniam a, Asthma symptoms te pawh a control tha zawk.

Engtin nge he damdawi hian a thawh hlawkzia i hriat?

Damdawi thar eng pawh market-a a lo chhuah hmain mihringah hman a him em tih leh a hlawk tak tak em tih hriat nan clinical study lian tak tak neih thin a ni. Tezspire hmang hian zirchianna lian tham pahnih neih a ni tawh bawk.

He zirchiannaa telte hi kum 12 leh a chunglam, asthma na tak nei an ni . Chu chu, steroid pill emaw damdawi ina dah ngai emaw, asthma attack fo tawhte tihna a ni.

Research hian thil engemaw zat a teh ber a ni:

• Asthma Exacerbations: Damdawi ei hnua Asthma attack awm tam dan a tlahniam dan kan en a.
• Lung function : Special test hian second khat chhunga boruak thar chhuah theih zat a teh thin. Hei hi Second 1 chhunga Forced Expiratory Volume an ti a - FEV1 .
• Symptom control: Zawhna bik (`Asthma Control Questionnaire 6` emaw ACQ-6 ) hmangin damlote chu an symptoms control tha em em tih enfiah a ni bawk.

Heng zirchiannaah hian hnam hrang hrang leh hnam hrang hrang te an tel a, mahse meizuk leh thawkna lam natna dang nei te chu heng zirchiannaah hian an tel lo.

He zirchianna hian eng nge a rah chhuah?

He zirchiannaa telte hian an hman thin asthma control damdawi (e.g. inhaled corticosteroids ) an ei chhunzawm zel a. Group pakhat chu Tezspire vaccine pek an ni a, group dang chu placebo pek an ni thung. Placebo hi damdawi ang maia lang mahse a takah chuan active medicine engmah a awm lo. Damdawi tak takte nghawng dik tak tehna atan hman a ni.

Kar 52 tawp, chu chu kum khat chhunga result hmuh chu a fuh tak zet a ni.

• Placebo group nena khaikhin chuan Tezspire dawngtu te hian asthma exacerbation (attacks) 56% atanga 72% in an tlahniam a ni.
• Tin, Tezspire ei tute zingah lung function, chu chu FEV1 chu litre 0.13 velin a pung bawk.
• ACQ-6 questionnaire-a a lan dan chuan Tezspire ei zinga 86% chuan an symptoms a ṭhat thu an sawi a, placebo group-ah chuan 77% chuan an natna lan chhuah dan a ṭhat thu an sawi thung.

Heng result te hian Tezspire hi asthma na tak control nan a tha hle tih a tilang chiang hle. Mahse research result hi mi zawng zawng tan a inang vek lo tih hre reng ang che. I result pawh a danglam thei.

Engtin nge Tezspire hi kan hmuh theih ang? Engtin nge hman ang?

I asthma hi control harsa a nih a, Tezspire i ngaihven a nih chuan i chhungkaw doctor emaw, pulmonologist emaw hnenah i sawi thei ang. I doctor chuan he damdawi hi i dinhmun nena inmil a tih chuan, i dawn theih nan a tul angin ruahmanna a siam ang.

Tezspire hi subcutaneous injection a ni a, kar 4 danah pek thin a ni.. Hei hi doctor office-ah emaw, clinic-ah emaw, damdawi inah emaw pek theih a ni tlangpui. A chang chuan, i doctor chuan in lama vaccine i pek hi a him a, a remchang a ni tih a rel thei bawk. Chutiang a nih chuan i doctor emaw, nurse trained emaw chuan vaccine pek dan tur dik tak a zirtir ang che.

Side effect leh thil hriat tur

Damdawi dang ang bawkin Tezspire hian side effect tenau leh a chang chuan na tak a thlen thei bawk. Hengte hi fimkhur a pawimawh hle.

Damdawi dangah harsatna a awm thei em?

Tuna thuthang awm dan chuan Tezspire hian damdawi dang nena inzawmna na tak a thlen nia sawi a la ni lo. Mahse, i damdawi ei zawng zawng, vitamin leh supplement i ei zawng zawng chu doctor hnenah hrilh vek a tha ber. Damdawi thar i ei tan hmain i doctor zawt fo ang che.

He damdawi avanga side effect i neih nia i rinhlelh chuan Tezspire vang a ni tih 100% i chiang lo a nih pawhin Colombo National Hospital-a National Poisons Information Center-ah report theih a ni. He thu hi nakin lawkah he damdawi chungchanga thu belhchian dawl zawk khawlkhawmna kawngah a pawimawh hle dawn a ni.