Type 2 Diabetes i nei em? A nih loh leh thinlung emaw thisen kalna kawng emaw natna? Chutiang a nih chuan i doctor chuan Empagliflozin tih damdawi, Jardiance tia hriat bawk chu a pe che a ni mai thei. He damdawi hi zunthlum vei lo mahse heart failure condition thenkhat nei te tan pawh pek thin a ni. Chuvangin, hei hi tuna mi tam takin damdawi an pek tawh a nih avangin vawiin hian chipchiar deuhin kan sawi dawn a, kan thianpa nen kan inbia ang maiin.
He damdawi Empagliflozin (Jardiance) hian engtin nge hna a thawh?
Hei hi scientific deuhin a lang thei a, mahse a awlsam hle. He damdawi hi damdawi chi khat, SGLT2 inhibitors an tih zingah a tel a ni. A hming kimchang chu Sodium-glucose co-transporter 2 inhibitor a ni.
Okay, tunah chuan a awlsam zawngin, hei hi a thleng ta a ni:
Kan kal (kidney) hian protein pakhat SGLT2 an nei a. A hna chu thisen atanga sugar (glucose) chu taksaah a lakluh leh a ni. Empagliflozin hian he protein SGLT2 an tih hi a block a ni. Then , kidney hian thisen a sugar tam lutuk chu taksaah a la lut leh lo va, chu ai chuan zun-ah a pass chhuak zawk thin. Filter-in thil duh loh a paih chhuak ang mai a ni. Chutiang chuan taksaa sugar level tam lutuk chu control a ni.
He damdawi hian kal atanga sodium (salt) taksaa lakluh lehna a ti tlem bawk. Hei hian thinlunga hnathawh tur a tihtlem phah a ni. Chuvang chuan he damdawi hi thinlung natna vei tan pawh a tangkai hle a ni.
He damdawi hi i hman hunah eng nge i beisei ang?
Empagliflozin hi ni khatah vawi khat i ei thin pill a ni. Nitin hun khata awm reng a tha ber. Doctor-te chuan zing lamah ei turin an ti tlangpui. Chaw ei rual emaw ei loh pawhin i ei thei bawk.
He damdawi hi chakna pahnih a awm a, chungte chu 10 milligram (10 mg) leh 25 milligram (25 mg) te an ni. I doctor chuan dose hniam zawkin a tan tir thei che a, a tul chuan a tipung thei bawk.
I theihnghilh chuan engtin nge i tih ang? Pill i ei theihnghilh chuan i hriatreng veleh ei nghal rawh. Mahse i pill dang ei hun a lo thleng tawh a nih chuan, i pill hloh leh a hnuhnung ber chu a rualin ei suh. Pill hloh chu skip la, a hnuaia pill chu a hun ruatah ei rawh.
A chang chuan i doctor chuan he damdawi hi zunthlum damdawi dang nen a pe ang che. Entirnan, metformin (Synjardy an tih) emaw, linagliptin (Glyxambi an tih) nen pill pakhat angin i dawng thei bawk.
He damdawi atanga hlawkna tam ber hmuh theih nan, ei leh in hrisel ei leh exercise neih fo a pawimawh , i doctor-in a rawt angin. Tin, nilengin tui tam tak in theihnghilh suh.
He damdawi hi i ei lai hian i doctor hian a chang chuan thisen test a nei ang a, i kal (kidney) a thawk tha em tih a enfiah ang. Tin, i thisen sugar level enfiah fo turin a hrilh bawk ang che. He damdawi hian a nghawng kimchang hriat theih nan thla 6 vel a ngai thei.
Hei hian eng side effect nge a neih?
Damdawi dang ang bawkin he damdawi hian side effect tenau te a nei thei bawk. Mahse, lungngai suh, a tam zawk hi chu an serious lo. Heng side effects te hi eng nge ni tih han thlir ila.
| Side effect a awm thei | Description leh tih tur |
|---|---|
| Side Effect awm tlangpui | |
| Genital Area-a Yeast Infection awm thei te | Hmeichhiaah a tam zawk a, mahse mipaah pawh a awm thei. A lan chhuah dan chu hnim hring, natna, hring, sen, leh tui chhuak te a ni. Hengte hi enkawl dan tur a awm a, chuvangin heng symptoms i neih chuan doctor rawn rawh. |
| Zun kawng natna (UTIs) . | Kang, natna, zun tam, zun chhum, thisen emaw ang chi natna lanchhuahna a awm thei. Pum na a awm thei bawk. Hengte hi enkawl a ngai bawk avangin doctor hnenah hrilh rawh. |
| Side effect tenau dangte pawh | Tuihalna nasa lutuk, zun tam, luak chhuak, ruh natna, leh ril natna te ang chi thil i nei thei. Hengte hi hun kal zelah i taksain damdawi a insiamrem avangin a bo tlangpui. An awm reng chuan doctor hnenah hrilh rawh. |
| Side Effect na tak tak, ngaihven vat ngai | |
| Urinary tract infection na tak tak a awm thei | Khawsik, khawsik, pum hnuai lam emaw, hnungzang emaw natna nasa tak. Hengte hi infection in kidney a nghawng tih chhinchhiahna a ni thei. Damdawi lam thurawn zawng nghal rawh. |
| Thisen sang a hniam | Luak chhuak, lu hah, a bik takin ding chungin. |
| Thisen thlum hniam | A bik takin zunthlum damdawi dang nena ei a nih chuan thawk hah, khur, lungphu sang, riltam, leh buaina ang chi symptoms a awm thei. |
| Fournier-a gangrene a ni | Hei hi mipat hmeichhiatna hmuna natna hlauhawm tak, na tak a ni. A lan chhuah dan chu a hmuna natna nasa tak, hring, khawsik, leh hah lutuk te a ni. Hei hi emergency a ni a, damdawi in Emergency Department (ETU) ah kal nghal rawh. |
| Zunthlum vei ketoacidosis a awm | Thisen sugar sang vanga natna khirh tak a ni. A natna lan chhuah dan chu tuihal lutuk, zun tam lutuk, pum na, rilru hah, chak lohna, thawk chunga thei rimtui te a ni. Hei pawh hi emergency a ni a, ETU ah kal nghal rawh. |
| Allergic Reaction awm thei te | Skin rash, hmai, hmui emaw, kawr emaw a hring, ei leh in emaw thawk harsa. Hei pawh hi emergency a ni a, damdawi lam pan vat rawh. |
Hman hmaa hriattirna leh himna atana fimkhur tur
He damdawi hi i ei tan hmain i damdawi ei zawng zawng (condition dang damdawi, vitamin, supplement, leh traditional medicine te pawh tel) i doctor hnenah hrilh hmasak a pawimawh hle. Empagliflozin hian a bik takin a hnuaia damdawi te hi a inzawm thei a ni:
- Zunthlum damdawi dang
- Thisen sang damdawi, ACE inhibitor leh Angiotensin receptor blocker (ARBs) te chu .
- Diuretics emaw "tui pills" emaw.
- Natna tidamtu aspirin, ibuprofen, leh naproxen te hi a ni
I doctor chuan damdawi dang i ei zat a thlak a ngai mai thei a, a nih loh leh a side effect chungchangah fimkhur zawk a ngai mai thei.
Ketoacidosis symptoms i neih chuan i doctor chuan i thisenah ketones a awm leh awm loh enfiah turin a ti thei bawk. Hei atan hian hmanraw bik emaw, zun test strip emaw a awm a.
Tui tam tak in theihnghilh suh , he damdawi hian dehydration a thlen thei a ni.
Zu i in a nih chuan doctor hnenah hrilh la, yeast infection emaw urinary tract infection emaw i neih fo chuan doctor hrilh rawh.
He damdawi hi tuin nge ei loh tur?
Empagliflozin hi mi zawng zawng tan a tha lo. He damdawi hi ei loh tur dinhmun thenkhat a awm a:
- Kidney dialysis i neih chuan.
- Nu hnute petu i nih chuan (damdawi hi hnute hnute hmangin naute hnenah a kal thei).
- Naupai emaw, naupai tum emaw i nih chuan (naute a tichhe thei a nih avangin hemi chungchang hi i doctor nen inbia ang che).
- Empagliflozin emaw a thil tel emaw allergy i neih chuan.
Tin, he damdawi hi Type 1 Diabetes vei tan pawh phal a ni lo a, Ketoacidosis vei theihna a tipung thei a ni.
Engtiang chiahin nge Empagliflozin (Jardiance) hi a thawh?
He damdawi hman tangkai dan hi clinical trial-ah pawh ziak tha tak a ni. Thla 6 chhung zet type 2 diabetes vei puitlingte zirchiannaah Empagliflozin:
- Fasting blood sugar level hi a tlangpuiin 19-25 velin a tlahniam thin.
- Thla 2-3 kalta chhunga thisen sugar level average tilangtu A1c value hi 0.7% - 0.8% in a tlahniam a ni.
Chu bâkah, mi ṭhenkhat chuan an taksa rihna pawh an tlahniam tawh bawk . Ni khata 10mg dose ei thinte hian an taksa rih zawng 2.5% vel an hloh a (entir nan, mi 90 kg tan 2.25 kg vel). 25mg dose ei te hian an taksa rih zawng 2.8% an hloh a (entir nan, mi 90 kg tan 2.5 kg vel).
He damdawi ei thinte zingah hian systolic blood pressure pawh a tlahniam deuh hlek bawk.
Take-Home Thuchah a ni
- Empagliflozin (Jardiance) hi zunthlum leh thinlung lam natna thenkhat enkawlna atana hman thin a ni. Kidney te hian taksa atanga sugar tam lutuk chu zun hmangin a paih chhuak thei a, hei hian hna a thawk a ni.
- He damdawi hi i doctor-in a pek ang chiah chiah, nitin hun khata ei thin ang che. Dose i miss a nih chuan a dawt lehah a rualin dose pahnih ei loh tur.
- He damdawi hmang hian zun kawng infection leh genital yeast infection te hi a awm fo thin. Heng symptoms te hi i neih chuan doctor hnenah hrilh rawh.
- He damdawi hian dehydration a thlen theih avangin nitin tui tam tak in thin ang che.
- Damdawi dang i ei zawng zawng chu i doctor hriattir a pawimawh hle.
- Allergy na tak, thawk harsa, Fournier’s gangrene, emaw ketoacidosis , ang chi natna khirh tak tak i neih chuan damdawi in emergency department (ETU) ah kal nghal rawh.
- Damdawi lam thurawn tel lo chuan he damdawi hi ei kha bansan ngai suh.
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