I doctor chuan depression emaw chronic pain ang chi natna atan damdawi a pe che em? Chu damdawi zingah chuan ‘tricyclic antidepressants’ tih hming hi i hre tawh em? Hengte hi damdawi thlah hlui deuh deuh ni mahse, a then phei chuan an la tangkai hle. Chuvangin vawiin hian heng tricyclic antidepressants, a tawi zawngin ``TCAs'' chungchang zawng zawng hi han sawi ila.
A awlsam zawngin, heng tricyclic antidepressant (TCA) te hi engte nge ni?
Tricyclic antidepressants (TCAs) hi damdawi chi khat a ni a, major depressive disorder symptoms control na tur a ni. An hmingah "antidepressant" tih thumal nei mah se, doctor-te chuan natna dang chi hrang hrang atan an pe bawk.
Hengte hi antidepressant hmuhchhuah hmasak ber an nih avangin "first-generation" antidepressant an ti bawk. An chemical structure-ah ring pathum an neih avangin "tricyclic" an ti a.
Tunlai hian depression damdawi thar zawk hi a him zawk a, side effect (SSRI ang chi) a nei tlem zawk avangin doctor-te chuan depression tan TCA an pe tam lo hle. Mahse, damdawi dang dawng lo mi thenkhat tan chuan an hlawk zawk mai thei. Condition dang atan pawh an hmang tlangpui bawk.
TCA chi hrang hrangte chu engte nge ni? Eng natna chi hrang hrangah nge doctor ten an prescribe thin?
Sri Lanka leh khawvel hmun hrang hrangah hian TCA chi hrang hrang hman a ni. I doctor-in damdawi a pek kha heng zinga mi a ni em tih enfiah rawh.
| Generic Hming a ni | Case hman tlanglawn tak tak te |
|---|---|
| Amitriptyline hmanga siam a ni | Depression, chronic pain, nerve pain, leh migraines te venna tur a ni |
| Imipramine a ni | Depression, naupang tê tête khum hnim hring |
| Nortriptyline hmanga siam a ni | Depression, natna rei tak nei |
| Clomipramine a ni | Ngaihtuahna leh thiltih duh loh zawnga awm thin Obsessive-Compulsive Disorder (OCD) tan a hlawk hle. |
| Doxepin a ni | Depression, lungkhamna, mut theih lohna |
A chunga kan sawi tak depression leh OCD bakah hian doctor-te chuan he damdawi hi natna dang engemaw zat atan an pe bawk. Hei hi "off-label hman" an ti a. Chumi awmzia chu damdawi hi a pawmpuina ni lo condition dang atan pek a ni tihna a ni a, chutih lai chuan research-in condition dang atan a tangkai tih a tarlang.
- Chronic pain: A bik takin nerve nena inzawm natna, diabetic neuropathy leh postherpetic neuralgia te hi a ni.
- Migraine ven nan: Migraine awm fo thin control.
- Mut theih lohna: Mi thenkhat chu an mut theih nan dose tlemte pek an ni.
- Lungkhamna (anxiety disorder) a awm
- Fibromyalgia: Taksa pumpuiah natna leh hahna a awm.
- Bedwetting: Hetiang dinhmun hi naupang tê tê tan pawh a ṭha ṭhin.
He damdawi hian taksaah engtin nge hna a thawh?
A awlsam zawngin sawi ila, kan thluak hian nerve cell inkara thuchah thawn chhuaktu chemical a nei a. Hengte hi neurotransmitter kan ti a . `Norepinephrine` leh `Serotonin` te hi neurotransmitter pawimawh tak tak pahnih, kan rilru put hmang, hlimna leh nungchang control tu an ni.
Heng level te hi depression ang chi dinhmunah chuan a hniam thei hle. TCAs hian thluaka heng neurotransmitters, ``Norepinephrine`` leh ``Serotonin`` te level tihsanin hna a thawk a, nerve cells inkara inbiakpawhna a tichak a ni.
Natna control hian heng damdawi te hian spinal cord atanga thluak thlenga natna signal te chu a block thin.
Mahse he process rual hian taksa chhunga receptor dangte pawh a block bawk. Chuvang chuan side effects, hmui vawt leh zun harsatna te a awm thin.
Heng damdawi te hian eng side effect leh risk nge a neih?
TCAs hian damdawi thar zawk aiin side effect a nei tam zawk deuh hlek a ni. Mahse, mi zawng zawngin an hmu vek lo. An tih chuan hun kal zelah taksain damdawi a hman thiam angin an tlahniam ang.
Side effect awm fo thin
- Kawng a vawt
- Ek khal
- Luak chhuak thei
- Mutthilh theih lohna
- Mit hmuh a fiah lo
Side effect dang a awm bawk
- Zun harsatna emaw, zun chhuah loh emaw
- Lung chakna sang (Tachycardia) .
- Orthostatic hypotension (ding emaw, tho emaw a thisen sang tlahniam) .
- Ei duhna a tipung a, taksa rihna a tipung bawk
Heng side effects te hian a tibuai che a nih chuan damdawi i chawlhsan hmain doctor nen inbiakna neih hmasak phawt ang che. A dose chu a siamrem thei a, a solution dang a rawn rawt thei bawk.
Case ngaihven bik ngai te
- Lung natna i neih chuan: TCA hian thinlung natna thenkhat a nghawng thei a, chuvangin i doctor chuan he damdawi hi i ei tan hmain EKG a ti duh mai thei.
- Epilepsy/fits i neih chuan: He damdawi hian seizures i neih theihna a tipung deuh thei.
- Naupai emaw, nau pai tum emaw i nih chuan: Naupai lai hian TCA hi a him vak lo a, chuvangin hemi chungchang hi i doctor nen inbiakna neih a pawimawh.
Pawimawh: Kum 25 hnuai lam thalaiten he damdawi hi an hman tan hian mahni intihhlum tumna a pung tlem hle. Nangmah emaw, i fa emaw hian heng ngaihtuahnate hi i neih chuan i doctor hnenah hrilh nghal rawh.
Overdose chungchangah i lungkham tur em ni?
Ni e, hei hi kan ngaihven tur a ni ngei ang. TCAs hi damdawi chi khat a ni a, overdose a ei chuan toxicity na tak a thlen thei a ni.
Mahse, i doctor-in a pek zat dik tak i ei chhung chuan he hlauhawmna hi a awm lo tih hre reng ang che. Overdose hi tihsual emaw, hriat lohna emaw, tumruhna emawa damdawi i ei tam lutuk chuan a thleng thei chauh a ni.
Chuvangin i damdawi chu i doctor-in a hrilh ang chiah chiah khan ei fo ang che. I pills te hi naupang leh ran vulhte hmuh theih lohna hmunah dah la.
Overdose natna lan chhuah dan
- Lungphung dik lo a awm
- Thisen sang a hniam hle
- Mutthilh nasat lutuk
- Seizures a awm thin
- Tremors a awm
- Dementia natna (dementia) a awm
- Coma state ah a awm
Nangmah emaw, i hriat miin emaw heng symptoms zinga pakhat tal i neih chuan tihkhawtlai suh. Ambulance dil turin 1990 call nghal la, a nih loh leh damdawi in hnai ber Emergency Department (ETU)-ah kal nghal rawh. A tul chuan Colombo National Hospital-a National Poison Information Center- ah pawh thurawn dil theih a ni.
Take-Home Thuchah a ni
- TCAs hi damdawi class hlui zawk, mahse a tangkai hle a, natna chi hrang hrang enkawltu a ni a, chung zingah chuan depression, chronic pain, leh migraine te pawh a tel.
- Hengte hian damdawi thar zawk aiin side effect a nei tam zawk a, mahse mi zawng zawngin an dawng vek lo. Side effects buaithlak tak tak i neih chuan i doctor nen inbia ang che.
- Damdawi ei zat hi thlak ngai suh la, doctor thurawn tel lo chuan ei nghal vat suh.
- Damdawi hi naupangte hmuh theih lohna hmun him takah dah fo ang che.
- Overdose a nih chuan a symptoms te chu hre reng ang che. Chutiang thil i rinhlelh chuan damdawi in hnai ber Emergency Department (ETU) ah kal nghal rawh.
- I damdawi ei dan, a that dan, a side effect chungchangah zawhna i neih chuan doctor zawt hreh suh. I tanpui turin a awm reng a ni.
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