IgA Nephropathy (Berger’s Disease) chungchang i zir dawn a, chu chuan ngawi rengin i kal a tichhia a ni.

Khawsik i neih hian i zun chu tea rawng a lo ni tih i hre ngai em? A nih loh leh i zun hian foam a nei tam tih i hmu em? Mi tam takin hengte hi thil pangngai anga an ngaih laiin, hei hi i kal (kidney)-a thil dik lo a awm tih hriattirna hmasa ber a ni thei. Vawiin hian IgA Nephropathy tih kan sawi dawn a, chu chuan kan taksa chu ngawi rengin a nghawng a, mi tam takin an la hriat ngai loh thil a ni.

A awlsam zawngin IgA Nephropathy chu eng nge ni?

Hei hi a takah chuan keimahni taksa hriselna lama harsatna avanga kal (kidney) tichhe thei natna a ni. A dik tak chuan hei hi autoimmune disease a ni .

Kan immune system hi ram humhimtu sipai angin han ngaihtuah teh. He sipai hian sipai chi khat bik an nei a, chu chu antibodies kan ti a ni. An hna chu taksaa lut hmêlma, virus leh bacteria ang chite zawn chhuah leh tihboral hi a ni. Chutiang antibody bik pakhat chu Immunoglobulin A, a nih loh leh IgA hi a ni.

IgA Nephropathy vei chuan taksaa IgA antibodies siam chhuah thenkhatah hian danglamna tlem, a nih loh leh tlakchhamna a nei a. Chuvang chuan kan immune system-a defender dangte pawhin he IgA mak tak hi an hre thei lo. Pawn lam atanga hmelma niin an ngai. Chuvangin, he IgA mak tak hi an bei a, an inzawm khawm a, clump lian tak tak an siam ta a ni.

He chhiatna hian kal (kidney) hian thisen a filter tha thei lo. Hei hian taksain a chemical balance a hloh phah a ni. Enkawl loh chuan he chhiatna hi end-stage kidney disease-ah a kal thei a ni.

He natna hi a chhan bik a awm em?

Scientist ten he natna thlentu dik tak hi an la hmuchhuak lo. Mahse, kai theih a ni lo. Genetic link a nei nia rin a ni. Chumi awmzia chu i chhungkuaa mi pakhatin a neih chuan nang pawhin i tihhmasawn theihna chance tlemte i nei tihna a ni.

Tin, damdawi lam dinhmun thenkhat chu hei hi a intan theihna tur ‘trigger’ a ni thei bawk.

He natna hi kum eng pawhah a vei thei a, mahse a lan chhuah tam ber chu kum 40 hnuai lam zingah a ni a, mipa pawhin hmeichhia aiin a let hnih zetin an vei tam zawk bawk.

A symptoms chu eng nge ni tih chiang takin i zawng chhuak ang u.

He natna chungchanga harsatna lian ber chu a tir lamah a lan chhuah loh vang a ni. Chuvang chuan mi tam takin he natna hi an nei tih pawh an hre lo.

Mahse, mi ṭhenkhatin an hriat chhuah ber leh langsar ber chu khawsik, flu, emaw, rilru natna ang chi an neih hian zunthlum (hematuria)-a thisen awm hi a ni Zun chu tea rawng, cola rawng, a sen pawh a ni thei. Infection a awm tawh chuan zun chu a rawng pangngaiah a kir leh ta a ni.

A lan chhuah dan ber dang chu zun (foamy urine) a ni . Hei hi zun atanga protein chhuak (proteinuria) avanga lo awm a ni.

Heng bakah hian natna lan chhuahna dang engemaw zat a awm thei bawk:

• Ke ah a hring a, a bik takin ke ruh ah a hring.
• Thisen sang (Hypertension).
• Natna hi rei tak a awm reng chuan kal (kidney failure) chhinchhiahna a lo lang thei a ni.

Engtin nge hei hi i hmuh theih, Doctor?

Heng symptoms te hi i neih chuan i doctor chuan zun test a ti hmasa ang a, zun chhunga thisen emaw protein emaw a awm leh awm loh a enfiah ang. Mahse, hengte hi kal natna dang tam takah hmuh theih a nih avangin a ringawt pawh hian IgA Nephropathy hi a nemnghet thei lo.

He thu i hriat hian hlauthawng suh. Hei hi damdawi ina tih thin routine test a ni. Doctor chuan i hnungzang a ti na ang a, i kal chhungah needle na tak tak a dah ang a, scanner hmangin i kal thlalak a la ang.Tissue tlemte tak tak an la a. Chumi hnuah microscope hmangin IgA clumps a awm leh awm loh leh kidney-a chhiatna engzat nge a awm tih enfiah a ni. He test hian natna a nemnghet mai bakah, doctor-in i tana enkawlna tha ber tur a relsak bawk.

Enkawl dan leh enkawl dan

Tunah hian he natna hi damdawi a la awm lo. Mahse, lungngai suh! Tunah chuan natna thunun thei, kal chhiatna tihziaawm thei, hrisel leh dam rei tak nei tura pui thei damdawi tha tak tak a awm ta.

Enkawlna tum berte chu:

• Thisen sang control dan tur.
• Zun atanga protein chhuak tihtlem.
• Kidney chhiatna tihziaawmna.

Chumi atan chuan i doctor chuan enkawlna hrang hrang a pe thei che a, chungte chu:

• Thisen sang damdawi: Hemi atan hian ACE inhibitor leh ARB ang chi damdawi hman a ni tlangpui. Hengte hian thisen sang a control mai bakah kal (kidney) venhimna kawngah pawh a pui bawk.
• Immune-suppressing damdawi: Steroid damdawi Prednisone emaw damdawi thar Nefecon ang chi emaw pek theih a ni a, hei hian kal a inflammation a tihziaawm thei a ni.
• Damdawi thar: Tunlai damdawi Sparsentan (Filspari) leh Iptacopan (Fabhalta) te hian zun atanga protein paih chhuah a tihtlem avangin kal hnathawh a venghim thei a ni.
• Diuretics: Taksaah hliam a awm chuan heng damdawi te hian zun kaltlangin tui tam lutuk a paih chhuak thei a ni.
• Cholesterol tihhniamna damdawi: Mi thenkhat chuan cholesterol level sang tak an nei thei. Chumi atan chuan statin ang chi damdawi an pe thin.

Nunphung thlak danglam hi a pawimawh hle

Damdawi bakah hian i nunphung tihdanglamna tenau te hian i kal venhimna kawngah kawng thui tak a zawh thei a ni.

• Salt intake tihtlem: I ei tur a salt awm zat tihtlem. Ei tur packaged leh artificial sweeteners ei loh tur. Chungte chu chi (salt) a tam hle.
• Protein control: I doctor emaw nutritionist emaw nen inbia la, i tana protein awm zat tur dik tak chu i hre thei ang. Protein ei tam lutuk hian i kal (kidney) ah extra strain a siam thin.
• Omega-3 fatty acids: Sangha hriak supplement hi a tha hle. Mahse, supplement i ei hmain doctor zawt hmasa phawt ang che.
• Painkillers pumpelh: Doctor thurawn lo chuan NSAID ang chi natna tidamtu (e.g. Ibuprofen, Diclofenac) ei loh tur. Hengte hian i kal (kidney) tan a tichhe thei a ni.
• Meizial zuk loh: Meizial in hian kal (kidney)-a thisen kal a ti tlem a, thisen sang damdawi hman thatna a ti tlem bawk.
• I thisen sang enfiah fo: In lamah i thisen sang teh la, record rawh.