He hming hi i la hre ngai lo mai thei. Epithelioid Hemangioendothelioma (EHE) hi cancer a ni a, a awm lo hle a, mi maktaduai khatah pakhat velin a vei thin. A hming hi a buaithlak deuh a, chuvang chuan a hlauhawm thei hle. Mahse, lungngai suh. He rare condition hi awlsam tak leh chiang taka hriatthiam a pawimawh. Chuvangin vawiin hian EHE hi eng nge a nih chiah kan sawi dawn nia.
A awlsam zawngin, EHE hi eng ang cancer nge ni?
Kan taksa pum puia thisen kalna kawng ( arteries , veins, leh capillaries) te hi ram pum huapa kawngpui inzawm ang mai a ni ang tih han ngaihtuah teh. Heng kawngpui chhungah hian cell layer te tak te tak tak a awm a. Heng cell te hi medical science-ah chuan endothelial cell an ti a.
Endothelial cancer hi thisen kalna kawng line siamtu cell-ah a intan a. Kan taksa chhung hmun tinah thisen kalna kawng a awm avangin EHE cancer hi taksa khawi hmunah pawh a lo awm thei a ni. Mahse, heng tumor te hi a tam ber chu liver, lung, a nih loh leh ruh atanga intan a ni . Mahse, hmun dang, lu, kawng, thyroid, pum, ovary, prostate, thluak leh ruhroah te pawh an lo thang lian thei bawk.
A châng chuan EHE hi lump pakhat angin a lang thei bawk. A chang chuan taksa peng pakhatah emaw, taksa peng hrang hrangah emaw lump tam tak angin a lang thei bawk. Vawi tam tak chu EHE hmuhchhuah a nih chuan cancer hi taksa peng pakhat aia tam ah a darh tawh a ni.
EHE hi sarcoma chi khat a ni em?
Ni e, a dik e. Sarcoma hi cancer chi khat a ni a, kan taksa peng nêm, thisen kalna kawng hrang hrangah a lo awm a. EHE cancer hi thisen kalna kawng endothelial cell atanga intan a nih avangin sarcoma chi khatah dah a ni.
Hei hi cancer natna tha lo tak a ni em?
Yes, EHE is malignant , chu chu malignant emaw cancer natna emaw a ni tihna a ni. Benign tumor ang lo takin heng cancer cell te hi thunun theih lohvin an thang lian thei a, taksa hmun dangah an darh (metastasize) thei a, tissue hrisel tak tak an tichhia thei bawk.
Mahse hetah hian hriat reng tur thil a awm. EHE cancer hi a buaithlak hle. EHE tumor thenkhat chu a darh chak hle a, cancer na tak ang maiin a darh chak hle. Mahse mi dangte chu an lo thang zawi zawi hle a, kum tam tak chhung chu an thang lian hle. Mak tak maiin heng tumor te hi enkawl ngai lovin an tlahniam tih report a awm tawh bawk. Hetiang nungchang danglam tak avang hian he cancer nasat dan leh enkawlna a dawn dan tur sawi lawk a harsa hle.
EHE natna lan chhuah dan chu engte nge ni?
EHE vei tam tak chuan a tir lamah chuan symptom engmah an nei lo. Hei vang hian natna dang test-naah accident-in hmuhchhuah a ni fo thin. Mahse, symptoms a awm tak tak chuan cancer lump awmna hmunah a innghat a ni.
A lan chhuah dan tlangpui thenkhat hmuh theih chu:
- Vun hnuaia hriat theih lump (hei hi a na thei a, a na lo thei bawk) .
- Chhan awm lovin taksa rihna tihtlem
- Khawsik leh hah lutuk
Cancer awmna hmun azira symptoms a danglam dan hi han thlir ila.
| Cancer awmna hmun | Symptoms awm thei te |
|---|---|
| Thin | Pum na, pum na. |
| Chuap | Thâwk harsa, khuh, thisen khuh, clubbing. |
| Ruh te | Ruh na, ruh tliak fo thin. |
| Spine a ni | Kal leh che harsa, hnungzang na. |
EHE cancer hi eng thilin nge a thlen?
EHE ang cancer hi cell hrisel tak chu cancer cell-ah a inthlak a, thunun theih loha a inthen tan hian a lo awm thin.
Hei hi eng nge a thlen tih hriat tumin zirchiangtute chuan genetic mutation bik avanga lo awm a ni tih an hmuchhuak a ni . A awlsam zawngin kan cell-a chromosome pahnih chu a inzawm dik lo va, chu chuan gene pahnih a inzawm khawm a ni. Heng genes te hi (WWTR1) ( (TAZ) tia koh bawk) leh (CAMTA1) an ti a. Heng gene pahnih hi an inzawm khawm chuan EHE cancer cells a lo piang tan ta a ni.
Chuvangin, i doctor pawhin diagnosis a siam hunah he chromosome association danglam tak hi a test thei bawk.
Engtin nge diagnosis hi siam a nih?
Kan sawi tawh ang khan EHE hi accident-a hmuhchhuah a ni fo thin. Doctor-te chuan imaging test, CT scan emaw MRI scan emaw-ah chauh he lump hi an hmu a, hei hi chhan dang vang a ni. Chumi hnuah chuan a awmna hmun, a lian leh te, leh hmun dangah a darh tawh em tih te an zawng chhuak thin.
Hengte hi EHE hriat theihna atana hman tlanglawn berte an ni.
| Fiahna | A awlsam zawngin, eng nge thleng? |
|---|---|
| CT Scan hmanga tih a ni | X-ray hmang hian i taksa chhungril cross-sectional image hrang hrang lak a ni. Hei hian rilru, pum leh pelvis-a EHE tumor awmte hriatchhuahna kawngah a pui thei a ni. Hei hian taksa peng hrang hrang, ruh leh ruh chhunga thil awmte chiang taka hmuh theih nan a pui a ni. |
| MRI scan (MRI) hmanga tih a ni. | Magnet chak tak leh radio wave hmangin taksa chhung lam thlalak chiang tak tak siam a ni. Hei hi liver leh ruh chhunga EHE tumor awm leh awm loh enfiahna atan a tangkai hle. A châng chuan taksa pum pui MRI, lu aṭanga ke thlengin taksa pum pui khuh hian ruh thlenga darh tawh tumor zawng chhuak thei a ni. |
| Core-Needle Biopsy hmanga tihchhuah a ni | Hei hi scan hnua lump chu EHE a nih leh nih loh finfiah nan test pawimawh ber a ni. Lump atang hian tissue te tak te chu special hollow needle hmangin an la chhuak thin. Specialist doctor pakhat, pathologist tia koh chuan he tissue piece hi microscope hmangin a enfiah a, cancer cell a awm leh awm loh leh eng chi nge a nih tih a hre thei a ni. |
Chu bakah, lumps hriatchhuah a, a darh tawh em tih enfiah nan (ultrasound) emawI doctor chuan test dang, PET scan ang chi pawh a rawt thei bawk.
EHE enkawl dan tur chu engte nge ni?
EHE hi chutiang khawpa natna hlauhawm tak a nih avangin a enkawlna tur standard treatment guidelines a la awm lo. Chuvangin, sarcoma enkawlna lama tawnhriat nei doctor multidisciplinary team-in an enkawl ang che. He team-ah hian surgical oncologist , radiologist , leh, cancer awmna organ (entir nan, ruh), orthopaedic surgeon , emaw, liver transplant specialist emaw a zirin an tel thei a ni.
Enkawlna i dawn dan chu thil engemaw zatah a innghat a, chung zingah chuan a hnah lian leh te, a awmna hmun te, a hnah engzat nge a awm tih te, leh cancer a darh leh darh loh te pawh a tel a ni.
Enkawl dan tur thenkhat chu hetiang hi a ni:
Fimkhur taka nghah
Symptoms i neih loh a, operation atana candidate tha tak i nih loh chuan i doctor chuan a tir lamah enkawl lo turin a rel mai thei a, i dinhmun chu uluk takin a enfiah mai thei bawk. Hei hi a chhan chu a chang chuan enkawlna avanga side effects hian a hlawkna a tluk phah thei a ni. Kan sawi tawh ang khan EHE tumor thenkhat chu enkawl lohvin an tlahniam emaw, an thang zawi zawi emaw a ni. Mahse, a natna a zual chuan i doctor chuan enkawlna dang a rawn rawt thei a ni.
Inzai
Tumor pakhat enkawlna hman tlanglawn ber chu surgery a ni. Hetiang tih danah hian surgeon chuan cancer natna hrik awm chu a la chhuak a, a chhehvela tissue hrisel tlemte chu a la chhuak a, chu chuan cancer cell a awm loh nan a enfiah thin.
Vascular Embolization hmanga enkawl a ni
Hei hian tumor thisen petu thisen kalna kawngte khap a huam a ni. Thlai chu tui pek i chawlhsan chuan a thi ang bawkin, thisen supply a tihtawp chuan tumor chu a thang lian thei lo va, a tlem thei lo bawk. Hei hi operation hmaa tumor tihtlem nan emaw, enkawlna ber atan emaw tih theih a ni. Transarterial chemoembolization (TACE) leh radioembolization te hi chutiang enkawlna pahnih a ni.
Targeted Therapy hmanga tih a ni
Hei hi advanced EHE enkawlna atana hman tlanglawn ber a ni. He enkawlna hian cancer cell te thanlenna atana an mamawh nutrients leh oxygen te block tu damdawi an hmang thin.
Radiation hmanga enkawlna a ni
He enkawlna hmang hian operation hnua cancer cell awm thei zawng zawng chu tihchhiat theih a ni. Surgery nei thei lo tan pawh radiation therapy hi enkawlna ber atan pek theih a ni bawk. He enkawlnaah hian targeted high-energy beams of radiation hmangin cancer cells te chu tihchhiat a ni.
Chemotherapy hmanga enkawl a ni
EHE (Chemotherapy) atan chuan .A hman tam lo hle a, mahse cancer chu a zual zel a nih chuan enkawlna dang nena hman dun a tha mai thei.
Organ Transplant tih a ni
Tumor tam takin taksa peng lian (a tam zawkah chuan liver) a nghawng a nih chuan doctor chuan taksa peng thlak (organ transplant) a rawt thei a ni.
EHE chungchanga zirchianna hi kalpui mek a ni a, enkawlna thar pawh clinical trial -ah enchhin mek a ni . I dinhmun a nasat dan azirin, i doctor chuan heng zirchianna hmanga enkawlna zinga pakhatah hian tel ve turin a rawt thei che a ni.
EHE nen hian eng chen nge i dam theih ang?
He thu i hriat hian, ‘Chuti a nih chuan eng chen nge ka dam theih ang?’ tiin i ngaihtuah mai thei. Dik tak chuan chu zawhna chu chhanna dik tak pek a harsa hle. EHE hi thil awm lo tak a nih avangin a chungchang hi information lakkhawm a la ni reng a ni.
Tin, a hmaa kan sawi tawh ang khan he cancer hi mi zawng zawngah hian a awm dan a inang lo. Mi thenkhat tan chuan cancer hi enkawl a nih pawhin a darh chak thei hle. Midang tan chuan cancer hi kum tam tak chhung a dam thei a, a lan chhuah dan lian tham a awm lo va, tumor pawh a darh thei bawk. Tumor thenkhat chu enkawl lohvin a tlahniam thin.
Chuvangin, i dinhmun leh i hmalam hun tur chungchanga hriat tur tha ber ber chu i enkawltu doctor hnen atangin chauh i hmu thei ang. I test report leh condition zawng zawng a ngaihtuah ang a, information dik ber ber a pe ang che.
I doctor zawh tur zawhna
Chutiang dinhmun hlauhawm tak i hriat chuan zawhna tam tak neih chu thil pangngai tak a ni. Doctor hmu tura i kal hunah heng zawhnate hi zawh theihnghilh suh.
| Zawhna zawh tur | Engvangin nge hei hi hriat a pawimawh? |
|---|---|
| Khawiah nge ka cancer natna hrik hi a awm? | Hmun a zirin symptom leh enkawl dan a inang lo. |
| Lump a lo lian em tih hriat theihna tur symptoms te chu engte nge ni? | Hei hian inthlak danglamna a awm chuan hriattir nghal vat turin a pui ang che. |
| Eng thilin nge ka dinhmun prognosis a nghawng? | Hei hi i dinhmun hriatthiamna dik tak neih nan a pawimawh hle. |
| Eng treatment nge ka tan i recommend? An side effects te chu engte nge ni? | Enkawlna chungchangah thutlukna chiang tak i siam thei a, a nghawng tha lo tur pawh i inpeih thei bawk. |
| Ka treatment team-a specialist-te hi tute nge ni? | I enkawltu team te chu hre chiang rawh. |
| Engzat nge follow-up turin ka lo kal a ngai dawn? | I hriselna chhinchhiah dan zir rawh. |
I rintlak doctor te hnen atanga enkawlna lak hi a pawimawh reng a ni. EHE ang chi rare condition chungchang sawi dawn chuan a pawimawh zawk. Hemi chungchang hi kan hriat loh tam tak a la awm avangin sarcomas leh complex cancer enkawlna lama tawnhriat nei doctor hnen atanga enkawlna zawng hian i dam lehna kawngah danglamna nasa tak a thlen thei a ni.
Take-Home Thuchah a ni
- Epithelioid Hemangioendothelioma (EHE) hi cancer chi khat a ni a, thisen kalna kawng line tu cell atanga intan a ni.
- He cancer awm dan hi mi hrang hrangah a inang lo thei hle. Ṭhenkhat chu an ṭhang chak hle a, ṭhenkhat erawh chu an ṭhang zawi hle emaw, enkawl lohvin an tlem emaw a ni.
- A tam zawkah chuan asymptomatic a ni a, chhan dang vangin scan an tih laiin accident-in hmuhchhuah a ni thei bawk.
- Diagnosis hriat chian nan biopsy neih a pawimawh hle.
- Enkawl dan hi damlo tinte nena inmil tura siam a ni a, enfiahna, operation, leh targeted therapies te pawh a tel thei bawk.
- Hei hi thil awm lo tak a nih avangin sarcoma lama tawnhriat nei specialist team hnen atanga enkawlna lak a pawimawh hle. I doctor hnenah zawhna zawt la, i dinhmun hi hriatthiamna tha tak nei rawh.
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