Whipple natna hi i hre tawh em? He hri kai hmuh tur awm lo tak hi thu awlsam takin han sawi ila!

A chang chuan i taksa chu a chak lo hle a, pum harsatna i nei a, ruh natna i nei a, mahse chhan i hmu thei lo em ni? Hei hi mi tam takin an hriat ngai loh natna a ni mai thei, mahse hriat a pawimawh hle. Vawiin hian chutiang natna hmuh tur awm lo, mahse uluk taka enkawl a nih chuan tihdam theih pakhat chungchang kan sawi dawn a ni. Chu chu Whipple natna a ni.

Whipple natna hi eng nge ni?

A awlsam zawngin, Whipple natna hi bacteria infection hmuh tur awm lo tak a ni a, i small intestine ah a awm thin . Hei hi i ei tur i ei that loh vang leh a mamawh nutrients te i taksaah a luh loh vang a ni (hei hi malabsorption'' an ti). Ngaihtuah teh, kan taksa tana chakna leh chaw tha kan neih theih nan chaw kan ei thin. Chuvangin a absorb tha lo a nih chuan harsatna tam tak a awm thei a ni. He natna hi Tropheryma whipplei'' tih hming pu bacteria taksa chhunga a luh chuan a lo awm thin. He bacteria hi leiah, chu chu leiah a awm tlangpui. Mahse thu lawmawm tak chu antibiotics'' dik tak hmang hian he bacteria hi taksa atangin paih chhuah theih a ni a, a natna lan chhuah dan a ti tlem thei a, a dam vek thei bawk

Whipple natna hi engtiang chiahin nge a hluar?

Hetah hian a pawimawh ber. He natna thlentu bacteria ((Tropheryma whipplei)) hi boruakah, a bik takin leia tam tak awm mahse, Whipple natna hi a awm lo hle a, a tlem hle a ni Damdawi lam zirchiangtute sawi dan chuan America ang ramah pawh hian mi maktaduai khat zinga mi 9 velin an vei nia chhut a ni. Chumi awmzia chu he natna hrik kai zawng zawng hian he natna hi an nei vek lo tihna a ni. A chhan dik tak erawh hriat a la ni lo.

Whipple natna lanchhuahna chu engte nge ni?

Whipple natna lanchhuahna hi a lang nghal lo. Stage engemaw zat chhungin an lo thang zauh zauh thin .

A hmasa ber (Prodromal Phase) atanga a lan chhuah dan .

A bul tanna chu ruh natna nasa tak atanga tan a ni . He natna hi a lo thleng thei a, a bo thei bawk. A bik takin i ruh lian tak tak – i ke ruh, i kekawrte, i hip, i khup, leh i kekawrte . Doctor-te chuan he early stage hi prodromal phase'' an ti fo thin.Hei hi kum sarih emaw kum riat emaw chhung a daih thei , chutah chuan symptom dang a lo lang tan thin. A chhan hmu lovin kum tam tak chhung ruh natna neih chu a harsat zia han ngaihtuah teh.

A hnu lama a lan chhuah dan

Hun engemaw chen hnuah a hnuaia symptoms te hi a lo lang thei bawk:

• Pum na: Pum na pangngai mai ni lovin, ei hnua natna zual zel emaw, a awm reng emaw pawh a ni thei.
• Diarrhea (tui hmanga bawlhhlawh): Ni khatah vawi eng emaw zat lo awm thin, tui awmna. Hei hian tui tlakchhamna nasa tak a thlen thei a, taksa atanga ei tur tha a hloh thei bawk.
• Swelling (Edema): Swelling i hmu thei a, a bik takin ke leh ke ruh ah hian a hring chhuak tih i hmu thei. I kut zungtang hmanga i hmet chuan dimple ang maia i hriat chuan edema a ni thei.
• Chauhna awm fo: 1.1.Eng ang pawhin muthilh mah la, i taksa chu nunna nei loin a inhria a, engmah tih duhna i nei lo.
• Fever: Chhan awm lova lumna hriat.
• Vun rawng danglam: Hmun thenkhat, a bik takin ni chhuahna hmun chu a tlangpui aia a dum thei.
• Swollen lymph nodes: Kawr, kawr leh kekawrte ang chi hmuna hnah te te a awm.
• Sawifiah loha taksa rihna tihtlem: Diet leh exercise la lovin taksa rihna tihtlem.

Central Nervous System chungchanga harsatna awm thei

Whipple natna vei zinga 20% leh 40% inkar chuan central nervous system lama harsatna an nei thin . Hei hi dinhmun pawi zawk a ni. A lan chhuah dan chu:

• Balance problems: I kal laiin i nghet lo hle a, ding nghet thei lo i ni.
• Buaina: I awmna hmun, hun leh i hriat mite pawh hriatna hloh.
• Chaw ei harsa: Chaw ei emaw, in tur emaw i ei laiin i rilru a buai ang maia inhriatna.
• Hriatrengna hloh: Tun hnaia thil thleng pawh theihnghilh.
• Mihring nun inthlak danglamna: I nihna ang kha ni lo ang maia inhriatna, thinrim awlsam leh buaithlak.
• Seizures: Thil hriatna hloh nghal leh convulsion.
• Thusawi lama harsatna: Thusawi thiam lo, chiang taka sawi theih lohna.

Whipple natna hi eng nge ni?

Doctor-te hriat dan chuan he natna hi leia awm bacteria chi khat (Tropheryma whipplei) avanga lo awm a ni . He bacteria kai apiang hi hri kai theihna an nei a ni. Mahse, a hmaa kan sawi tawh ang khan Whipple natna hi a tlem hle. Chuvangin, engvangin nge mi thenkhat chauhvin an neih tih hi a la chiang lo .

Mahse, zirchianna chuan a hnuaia thilte hian natna kai theihna a tipung thei tih hmuhchhuah a ni :

• Kum: Whipple natna hian kum 65-84 inkar mi a vei tam ber tih hmuhchhuah a ni a, mahse chu aia naupang zawkah pawh a vei thei bawk.
• Lei emaw ran vulhna lama inhriatthiamna: Zirchianna atanga a lan dan chuan leia emaw ran vulh lama thawktute chu he natna hi an vei theihna a sang zawk a ni. A bik takin, lo neitute, huan nei emaw, rannung nena thawk ho emaw chu an hlauhawm zawk thei. I in huana thil te tak te i phun hian he bacteria hi i tawk thei hial a ni.
• Genetic mutations te chu: 1.1.Whipple natna leh protein (IFR4) siamtu gene hi inzawmna a awm a. He protein hian kan taksa immune cells, (B cells) leh (T cells) te chu a lo thang lian thei a ni. Tin, gene (HLA-B27)-a mutation nen pawh a inzawm tih hmuhchhuah a ni bawk. Hengte hi a thuk zawk deuh a, mahse a awlsam zawngin kan genes-a inthlak danglamna thenkhat hian hetiang hi min siam thei a ni.
• Immune system chak lo: I immune system tichhe thei natna (HIV ang chi) i neih chuan, emaw, immunosuppressants (hei hi natna thenkhat tan pek a ni a, a chang chuan arthritis ang chi thil atan emaw, taksa peng thlak hnuah emaw pek thin) i ei a nih chuan, he natna hi i vei theihna chance a sang zawk bawk.

Whipple natna avanga harsatna awm thei te chu engte nge ni?

Kan sawi tawh ang khan Whipple natna hi i taksain i ril te tak te kal tlanga ei tur atanga thau, carbohydrates, vitamin leh nutrient dangte tha taka a lakluh theih loh vang a ni. Natna zual zel a ni a , hun kal zelah a na zual zel a ni . Chumi awmzia chu enkawl loh chuan hriselna lama harsatna thar, pawi tak a lo awm thei tihna a ni.

Hetiang ang harsatna hi a awm thei a ni:

• Anemia (thisen sen zat hniam): Hei hian hahdamna, chak lohna leh vun rawng a ti hring reng thei.
• Dementia (hriatrengna leh rilru hnathawh hloh): Hei hi nervous system a nghawng chuan a thleng thei.
• Heart murmur: Hei hi doctor-in stethoscope hmanga a enfiah che hian hriat theih a ni.
• Oculomasticatory myorhythmia: Hei hi a lan chhuah dan chiang tak a ni a, mit leh hmui chu a inrem ang maiin a lang .
• Pleural effusion: Hei hian thawk harsatna a thlen thei.
• Uveitis: A lan chhuah dan chu a sen, natna, leh mitdelna te a ni thei.

A pawimawh ber chu Whipple natna hian i central nervous system a nghawng a nih chuan a thihpui thei a ni. Chuvangin symptoms i neih chuan doctor pan nghal a pawimawh.

Engtin nge doctor-te hian Whipple natna hi an hriat theih?

Doctor hmu tura i kal chuan taksa enfiahna a pe hmasa ang che . Tichuan, i medical history , tuna emaw, tun hmaa emaw hriselna lama harsatna i neih tawh zawng zawngte pawh tiamin, an zawt ang. Damdawi i ei dan leh i chhungte zingah heng natna te hi an nei tawh em tih te pawh an zawt thei bawk. Chu bakah, a hnuaia test te hi an ti thei bawk:

• Complete Blood Count (CBC) : Hei hian taksa thisen cell awm dan te, thisen tlakchhamna (anemia) a awm leh awm loh a enfiah a, natna kai chhinchhiahna a awm leh awm loh a enfiah thin.
• Upper endoscopy hmanga intestine te tak te a awm: Hetah hian camera te tak te nei tube chu ka chhungah dahin small intestine chhungah an en a. Hetiang hian chutah chuan inthlak danglamna eng pawh, hri kai chhinchhiahna te chu enfiah theih a ni. Hei hi tih a nih hma chuan mut tir i ni ang a, chuvangin natna engmah i nei lovang.
• Polymerase Chain Reaction (PCR) test : Hei hi test bik a ni a, bacteria (T. whipplei) a awm leh awm loh hriat theih nan a pui thei a ni. Biopsy atanga lak tissue piece pakhatah emaw, taksa tui dang lakah emaw pawh tih theih a ni.
• Small intestine biopsy : Endoscopy an tih lai hian small intestine atanga tissue te tak te lakchhuah a ni a, microscope hmangin an enfiah thin. Hei hi Whipple natna finfiah nan an hmang fo thin. Bacteria avanga intestinal tissue-a inthlak danglamna chiang tak a zawng thei a ni.

Whipple natna hi engtin nge enkawl a nih?

Whipple natna thlentu bacteria taksa atanga paih vek tur chuan hun rei tak a ngai a ni . Chuvangin enkawlna hi a rei deuh hlek a ni. Mahse i dawhtheih chuan result tha tak i hmu thei a ni.

Enkawlna anga tih thinte chu hengte hi a ni:

• Antibiotics : Enkawlna hi a tlangpuiin intravenous (IV) antibiotics hmangin kar hnih atanga kar li chhung a tan thin . Hei hi damdawi inah tih a ni fo. Chumi hnuah chuan thla 12 chhung tal chu oral antibiotics i ei a ngai dawn a ni . A châng chuan, rei zâwk, kum hnih thleng i ei a ngai mai thei. Damdawi hi doctor-in a tih ang chiah chiah ei a pawimawh hle.
• Fluid thlak : Diarrhea avanga tui tlakchhamna i neih chuan IV fluid pek i ni thei a, chu chuan a tihtawp theih nan a pui thei bawk. A nih loh leh, tui leh chi bo tawhte thlak nan electrolyte in tur (Jevani ang chi) in turin an ti mai thei bawk.
• Vitamins leh nutrient supplement : I doctor chuan vitamin (vitamin D, B12, leh iron ang chi) leh i intestines-in a hip tha thei lo nutrients te tihpunna tur supplement ei turin a rawt mai thei. He natnaah hian ei leh in lama harsatna a awm fo thin.

Enkawlna hian side effect a nei em?

Ni e, side effect thenkhat chu a awm thei a, a bik takin antibiotics hmang hian. Mahse hengte hi mi zawng zawngah a thleng vek lo va, a thleng pawh ni se, a tlangpuiin a serious lo.

• Diarrhea (ril a na) .
• Luak chhuak thei
• Nausea leh luak chhuak
• Vun a hring chhuak
• Yeast infection (a bik takin hmeichhiaah chuan vagina-ah) .

Hetiang thil hi a thleng a nih chuan doctor hnenah hrilh a pawimawh . Damdawi an thlak danglam thei emaw, a side effect tihziaawmna tur thil dang an pe thei che emaw a ni thei.

Whipple natna vei chuan eng nge a tawn?

Mi tam tak ang bawkin nang pawhEnkawl i tan tirh chuan hahdamna i nei nghal vat ang. Pum na leh ruh na te chu a reh zauh zauh ang. Mahse, i intestine te chu a dam kim theih nan kum hnih vel a ngai thei . Chuvangin inenkawlna kawngah dawhthei taka kan awm a pawimawh.

A tam zawkah chuan Whipple natna hi enkawlna hmangin a dam vek a ni . Mahse, a chang chuan enkawl zawh hnuah natna hi a lo let leh thei a ni. Chuvang chuan doctor ten an check chhunzawm zel ang che.

I doctor chuan hun rei tak chhung regular follow-up test neihpui turin a rawn lut ang che. Entirnan, upper endoscopy nei turin an ti thei che a ni:

• Thla ruk danah enkawl kum khatna atan .
• Kum thum chhung atan kum khatah vawi khat .
• Tichuan kum thum danah vawi khat chu i dam chhung zawngin .

Hei hi natna a lo awm leh tawh em tih enfiah nan tih a ni. Chuvangin, Doctor-in a rawt angin follow-up visit-te hi lo tlawh loh tur a ni.

Whipple natna hi ven theih a ni em?

Chu chu sawi harsa deuh a ni. A chhan chu Whipple natna thlentu bacteria te hi kan chhehvel hmun tinah te, a bik takin leiah te an awm vek a ni . Mahse, a kaihhnawih zawng zawng hian Whipple natna hi an vei vek lo.

Mahse, taksa chak lohna nei emaw, immunosuppressant ei thin emaw te chu he natna hi an vei theihna a sang zawk. Heng mite zinga mi i nih chuan lei emaw, lei emaw hmanga hnathawh apiangin kutkawr vuah a tha a, hnathawh zawhah pawh uluk takin kut sil a tha A bik takin huan i enkawl emaw, rannung nena hnathawh emaw i nih chuan fimkhur hle ang che.

Engtin nge ka in enkawl ang?

A pawimawh ber chu doctor-in a sawi angin antibiotics ei hi a ni a, a hun chhung zawng zawng . Ni khat pawh tlai lo la, damdawi chu doctor-in a pek hun chhung zawng zawng ei rawh. Mi tam zawk chuan an natna an hmuhchhuah hnuah kum khat tal antibiotics an ei a ngai dawn a ni . Mi thenkhat chuan an dam chhung zawngin antibiotics an ei a ngai mai thei. Chu chu doctor-in a rel tur a ni.

Whipple natna i neih hian i taksain ei tur pawimawh tam tak a hloh mai thei . Enkawlna atanga hahdamna i hmu a nih pawhin, i ei leh in tur chungchangah dietitian rawn hmasa phawt a tha . Hei hian ei leh in dik tak i neih theih nan leh i taksa rihna hrisel tak i neih theih nan a pui ang che.

Engtikah nge Doctor ka hmuh leh ang?

Enkawl i tan hnu pawha Whipple natna lanchhuahna i neih chhunzawm zel a nih chuan , emaw, enkawlna a tawp hnu lawkah (entir nan, pum na emaw, ruh na emaw i neih chuan) i doctor pan ngei ngei tur a ni. Tikhawtlai suh. Hei hian natna chu a lo kir leh tawh tihna a ni thei a, harsatna dang a awm thei tihna a ni thei bawk.

Engvangin nge he natna hi "Whipples disease" an tih?

Hei hi hriat a tha. He natna leh a thlentu bacteria hming hi George H. Whipple, pathologist hming chawia sak a ni a , kum 1907 khan a natna lan chhuah dan a sawi hmasa ber a, kum 80 hnuah chauh zirchiangtute chuan he natna thlentu bacteria hi an hmuchhuak ta a ni. An natna hrik chu Tropheryma whipplei tiin an vuah a. He hming hi Greek tawng pahnih inzawmkhawm a ni a, "trophe" tih awmzia chu nutrition tihna a ni a, "eryma" tih awmzia chu obstruction tihna a ni . Malabsorption a thlen tihna a ni . Hming inhmeh tak a ni lo maw?

Bacteria hi kan chhehvel hmun tinah (leh kan taksa chhungah) a awm a. A tlangpuiin nitin kan tawn thin bacteria te hian min tibuai lo. Mahse he bacteria infection hmuh tur awm lo, Whipple natna hi a danglam deuh hlek a ni. Leia awm bacteria tlanglawn tak Tropheryma whipplei atanga lo chhuak a ni.

He bacteria (T. whipplei) hi hnathawhna hmunah emaw, huan enkawl lai emaw pawhin i kai thei a ni. Mahse, a kaihhnawih zawng zawng hian Whipple natna hi an vei vek dawn lo. Vanneihthlak takin he natna hi a hmaa hriat chhuah a, uluk taka enkawl a nih chuan a dam thei fo thin.

I hriat reng tur pawimawh ber berte

Whipple's Disease hi bacteria infection hmuh tur awm lo tak a ni a , mahse enkawl tha a nih chuan a dam thei a ni .

• Ruh natna, pum na, ril\am, leh taksa rihna tlahniam ang chi symptoms a awm reng chuan doctor pan ngei ngei tur a ni. Hengte hi ngaihthah suh.
• Enkawlna atan hian antibiotics rei tak ei a ngai a . Anmahni zawm dik a pawimawh hle.
• Lei hmanga hnathawh i nih chuan, a bik takin i taksa hriselna chak lo i neih chuan i kut kha uluk takin silfai la, kutkawr hmang rawh .
• Natna a dam tawh hnuah pawh Doctor-in a tih angin regular check-up (follow-up) neih a pawimawh hle.

He natna hi hlau suh. Hriatthiamna leh damdawi lam thurawn lak a pawimawh. Nangmah chauh i ni lo va, eng harsatna pawha pui theitu doctor an awm bawk. Rinhlelhna i neih chuan Doctor biak hreh suh.