I thluak hmun var (White Matter Disease) tibuaitu natna i hre tawh em? Kan sawi dawn nia!

I kum upat deuh deuh hian i hriatrengna chu a chhe deuh deuh niin i hria em? A nih loh leh, i kal emaw, thil i tih emaw hian tlem chuan balance tlem zawkin i inhria em? Chûngte chu kum upat ruala thil pangngai lo thleng a ni thei. Mahse, a chang chuan heng symptoms hnuaiah hian chhan tlem a awm thei a, chu chu tlem a fimkhur zawk tur a ni. Awle, vawiinah hian kan thluak var (white matter) tichhe thei dinhmun pakhat kan sawi dawn a ni.

He natna thluak hmun var (White Matter Disease) tibuaitu hi eng nge ni?

A awlsam zawngin kan thluaka white matter chhiatna leh inthlak danglamna sawina tlangpui a ni. He white matter hi kan thluak hmun hrang hrang inzawmkhawmtu "highway" network angin han ngaihtuah teh, chubakah thluak leh ruhro pawh a inzawm khawm bawk. Buaina hi heng "highway" te hi a chhiat atang hian a intan thin.

Hetiang dinhmun hi cerebral small vessel disease emaw microvascular disease emaw an ti bawk . Kum upa lam leh thluaka white matter-a thisen kalna kawng inthlak danglamna nen a thleng thei a ni. A na lo thei a, a na lo thei a, a na thei bawk .

I white matter a chhiat chuan white matter lesion a lo ni ta a ni . Doctor-te chuan thluak magnetic resonance imaging (MRI) scan-ah hengte hi bright spot angin an hmu thei a ni. A châng chuan heng hliamte hian natna lan chhuahna lian tham a thlen lo thei a, kan tar chhoh zel chuan a ṭhen hi "normal" tak a ni. Mahse, hliam thenkhat chuan thluaka "highway" pawimawh tak takte a tichhia thei a, hriatrengna, balance, leh kal kawngah harsatna a thlen thei a ni .

A tlangpuiin, white matter lesions tam zawk (chu chu white matter natna tam zawk) nei te hian symptoms an nei tam zawk thin .

He white matter natna hi cardiovascular disease risk factors nen a inzawm tlat a ni . Researcher te chuan biomarker a nih thu an ring a, chu chuan dam chhung zawnga stroke, dementia leh disability te a thlen theihna a tilang a ni.

He white matter hi eng nge ni tak tak?

White matter hi kan thluaka nerve fibers (axons) network lian tak a ni. Hei hi thluak hmun hrang hrang inkara thu inthlengna leh inbiakpawhna a awmna hmun a ni. Heng nerve fiber te hi myelin tih hming puin a hual vel avangin "white matter" an ti a ni. Chu myelin avang chuan he tissue hian a rawng dum a nei ta a ni.

I thluak hian a chung leh a thuk lamah gray matter a nei a. A rawng sen (gray color) hi nerve cell (neurons) cell body atanga lak a ni.

Kan white matter hi a hrisel theih nan thisen supply tha leh nutrients tha tak a mamawh a ni .

Kan huana thlai hian a mawi taka a lan theih nan tui, ni eng leh rake a mamawh ang bawkin, thluaka thil var (white matter) hian thisen tha leh ei leh in tha a tlakchham chuan a tichhe thei a ni.

Thisen supply tlahniam (damdawi lama ischemia tia hriat) leh nutrient tlahniam hian heng nerve fiber te hi a tichhe thei a ni. An lo hring thei a, an chhe thei a, an thi vek thei bawk.

He white matter natna hian tute nge a tuar ber?

Tu chungah pawh a awm thei a, mahse kum 60 chunglam leh rilru lam natna nei teah a awm tam ber .

Thalai thenkhat, entirnan, migraines ang chi natna nei te chuan thluak MRI scan-ah white matter lesions tlemte an nei thei. Mahse, kum upat leh rilru lam natna vei theihna tur control loh risk factors a pun chhoh zel chuan heng lesions hi a pung zel a rinawm.

Mi thenkhat chuan genetic risk factors vangin he natna hi an vei tam zawk thei bawk .

Hetiang dinhmun hi engtiang chiahin nge a awm?

White matter natna hi a awm fo , kum 60 chunglam zinga a chanve aia tam a vei.

He white matter natna hi engte nge a lan chhuah?

Hetiang dinhmunah hian symptom lang thei thenkhat chu hetiang hi a ni:

• Memory lama harsatna a awm .
• Zawi zawiin a kal .
• Balance issue leh tlak fo thin .
• Vawi khata thil pahnih emaw a aia tam emaw tih harsat , entirnan, thusawi laiin kea kal.
• Mood swings , depression ang chi dinhmun te .
• Zun control harsatna (urinary incontinence) .

Heng symptoms te hi natna khirh zawk nei te zingah a tam zawk .

Mahse, chûng chhinchhiahna tam tak chu tar nêna lo awm inthlâk danglamna pangngai avânga lo awm thei a ni tih hre reng ang che, a nih loh leh damdawi lam thil dang , ruh natna, zunthlum kaihhnawih neuropathy, Alzheimer’s dementia, a nih loh leh mut theih lohna Mahse, heng symptoms te hi a lo lang a, a na zual thuai a nih chuan ngaihtuahawm tak a ni.

A châng chuan, thluak MRI an tih hian chhan dang vangin white matter natna hi a thleng mai maiin hmuhchhuah a ni ṭhin. Mi thenkhat chuan nei mahse symptom engmah an lantir lo (asymptomatic). I natna lan chhuah dan hi white matter natna vang nge, thil dang vang nge tih hriat tumin doctor nen inbiakna neih a tha ber.

Eng thilin nge he white matter natna hi a thlen?

He natna leh a chhante hi zirchiangtute chuan an la chhui mek a ni. Tunah hian white matter-a nerve fiber-a thisen kal rei lutuk (chronically reduced blood flow) hi a chhan niin an ngai.Hei hi a chhan chu heng fiber te hi a chhiat vang a ni.

Kan tar chhoh zel chuan kan thisen kalna kawngte chu a nghet zual a, a elastic lo . Hei hian thluaka nerve-a thisen kal a tihtlem thei a, chu chuan white matter a tichhe thei a ni.

Atherosclerosis tih natna avang pawh a ni thei bawk . Hei hi hun kal zelah kan thisen kalna chhungah plaque a lo awm khawm a , chu chuan thisen kawng bang a ti thim a, a khauh phah thin. Hei hian taksaa thisen kalna kawng eng pawh a nghawng thei a, thluaka thisen kalna kawngte pawh a nghawng thei a ni.

Cardiovascular risk factors neih hian i thluaka white matter lesions a tipung thei a, chu chu thisen sang, zunthlum avanga thisen sugar level sang, ei leh in a cholesterol sang, leh meizuk .

White matter lesions awm chhan dangte

Myelin-a khuh nerve fiber-a chemical composition tihdanglamna, tihchhiat emaw, thisen supply tihtlem (ischemia) thlentu process eng pawh hi MRI scan-ah white matter lesions angin a lang thei a ni.

White matter natna hi vascular problem avanga white matter lesions awmkhawmna ni mahse, chhan dang vangin white matter lesions te te pawh i nei thei bawk. Entirnan, heng natna te hi demyelinating inflammatory disorders multiple sclerosis (MS) leh genetic condition leukodystrophy -ah te hmuh theih a ni.

Doctor, neurologist leh neuroradiologist te chuan MRI scan hmangin thluaka an awmna a zirin white matter natna leh hliam awm chhan dangte chu an thliar hrang thei fo thin. A châng chuan MRI scan-a white matter lesions hmuh chhuah chhan dik tak hriat theih nân test dang neih belh a ngai ṭhin.

Engtin nge he white matter natna hi hmuhchhuah a nih?

He natna hi hriat theih dan ber chu thluak magnetic resonance imaging (MRI) scan hmangin a ni . MRI scan hi natna nei lo test a ni a, taksa peng hrang hrang thlalak chiang tak tak a siam a ni. MRI machine hian magnet lian tak, radio wave leh computer hmangin heng thlalak chipchiar tak takte hi a siam chhuak a, engmah radiation (X-ray hman loh) hmang lovin.

Brain MRI scan hian doctor-te chu i thluaka white matter tihchhiat nasat zia a hriat theih nan leh white matter natna a hriat theih nan a pui thei a ni.

White matter inthlak danglamna hi MRI-ah chuan lesion angin a lang. Heng white matter inthlak danglamna te hi MRI report-ah hian kawng hrang hrangin an label thei a:

• Cerebral emaw subcortical white matter natna emaw, hliam emaw a awm thei.
• Microvascular natna a ni.
• Non-specific white matter a inthlak danglam thin.
• T2 hyperintensity (hliam) a awm.

A châng chuan, i doctor chuan natna dang i neihna MRI scan result aṭangin white matter natna chhinchhiahna a hmu thei a ni. A châng dangah chuan i doctor-in i natna lan chhuah chhan chiang tak dang, balance leh hriatrengna lama harsatna te a hmuh loh chuan MRI a ti thei bawk.

Imaging test dang awm mahse, CT scan (Computed Tomography scans) , magnetic resonance imaging (MRI) hian white matter natna hriat theihna atan image quality leh sensitivity tha ber a nei a ni.

He natna hi i hriatchhuah hunah i doctor chuan i natna lan chhuah dan tehna atan neurological exam pawh a nei thei bawk.

White matter natna hi cardiovascular disease risk factors nen a inzawm avangin i doctor chuan i risk tehna atan hetiang thisen test hi a ti thei bawk ang:

• Metabolic panel kimchang tak a awm .
• Lipid panel (cholesterol level en rawh).
• Glycosylated hemoglobin test (HbA1c) (Diabetes dinhmun en rawh).

He white matter natna hi engtin nge enkawl a nih?

He natna enkawl hian doctor-te chuan a natna lan chhuah dan enkawl leh rilru lam natna nena inzawm risk factors control-na lam an ngaihtuah ber a ni.

Hriselna lama harsatna awm thei, thisen sang, zunthlum, leh cholesterol sang te enkawl te, meizuk bânsan te hian white matter lesions dang a awm loh nan a pui thei a ni

White matter chhia tawh siamthatna tur enkawlna awm lo mahse, hriselna lama harsatna thunun theih loh zawk nei te chuan a tlangpuiin white matter chhiatna leh chak lohna an nei tam zawk thin.

White matter symptoms te enkawlna

• Physical therapy : Hei hian white matter natna avanga balance leh kalna lama harsatna awm thei te tan a pui thei a ni. Tlu lo tura zirtirna leh enkawlna te pawh a huam tel bawk.
• Psychological counseling leh psychiatric treatment : Rilru lam harsatna, depression ang chi tan chuan psychologist nen inbiakna hmangin symptoms te chu control theih a ni a, a tul chuan psychiatrist hnen atanga antidepressant dawngin
• Urinary incontinence : Hei hi enkawlna hrang hrang a awm a, chung zingah chuan damdawi, nunphung thlak danglam, leh damdawi lam kalphung thenkhat te pawh a tel.

Cardiovascular disease risk factor enkawl dan tur ruahmanna siam a ni

Cardiovascular disease nena inzawm risk factors enkawl hian white matter disease lo zual zel dan tur a control thei a, stroke ang chi cardiovascular events nunna atana hlauhawm tak takte pawh a veng thei bawk.

Cardiovascular disease risk factors enkawlna atana puitu enkawlnate chu:

• Thisen sang hrisel vawng reng turin damdawi leh nunphung thlak danglam .
• Diabetes enkawl dan (zunthlum i neih chuan).
• Damdawi hmanga cholesterol level control leh nunphung thlak danglam .
• Exercise neih fo thin .
• Meizial zuk loh tur .
• Zu in loh tur .
• Antiplatelet damdawi (hei hi thisen cell inzawmkhawm leh thisen zam siamna tur damdawi pawl khat a ni).
• Statins (i cholesterol level chu a normal a nih pawhin, hengte hian thisen kalna kawnga inflammation tihziaawmna kawngah a pui thei a ni).

He white matter natna hi eng ang doctor nge enkawl?

I natna lan chhuah dan leh i dinhmun a zirin heng doctor pakhat emaw a aia tam emaw hi white matter natna lan chhuah dan enkawl nan leh a kal zel dan enfiah turin i hmu thei ang:

• Neurologist a ni
• I chhungkaw doctor (Primary care provider) .
• Taksa lam enkawltu a ni
• Occupational therapist a ni
• Taksa lam doctor
• Cardiologist a ni
• Urologist (Urologist) a ni
• Psychologist leh/ emaw Psychiatrist emaw a ni

He white matter natna hi ven theih a ni em?

Zirna hrang hrangah chuan rilru lam natna vei theihna tur risk factor nei te chu white matter disease vei an tam zawk tih hmuhchhuah a ni.

Cardiovascular disease vei theihna tur risk factors te chu:

• Thisen sang (Hypertension) 1.1.
• Cholesterol sang (Hyperlipidemia, Dyslipidemia) 10. A rilru a hah lutuk chuan a rilru a buai em em a.
• Meizial zuk
• Zunthlum control tha lo

He natna kal zel dan tur thunun nan hian thil tih theih a awm . Zirna hrang hrangah chuan heng risk factors te, damdawi ei te, nunphung thlak danglam te, leh/ emaw meizuk bânsan te hi enkawl hian white matter lesions thar siam a veng thei tih a tarlang.

White matter natna hi eng prognosis nge ni?

White matter natna hi MRI-ah chuan natna chi hrang hrang a ni a, a na lo atanga a nasat thlengin a awm thei. A kaihhnawih symptoms chu engmah lo atanga na tak thlengin a awm thei. Chuvangin, white matter natna vei tur thlirna hi mi hrang hrangah a inang lo.

White matter natna i vei tih hmuhchhuah i nih chuan i neurologist nen i beisei theih tur chungchang sawipui a tha ber.

White matter natna chungchangah engtikah nge doctor i hmuh ang?

White matter natna i vei tih hmuhchhuah a nih chuan i primary care physician hmu fo a , i risk factors enkawl dan tur sawiho a pawimawh. I white matter natna awm dan leh a nasat dan azirin, leh i natna lan chhuah dan azirin, specialist dang i hmuh a ngai thei bawk.

White matter natna i neih chuan i cardiovascular health hi dah pawimawh hmasak a pawimawh. Entirnan, i cholesterol leh thisen sang control nana damdawi ei leh nunphung tihdanglam hian white matter lesion thar lo awm tur venna atan a pui thei a, stroke leh dementia i vei theihna a ti tlem thei bawk. Hetiang dinhmun emaw, rilru lam natna hlauhawmna emaw chungchanga zawhna i neih chuan doctor zawt rawh. Anni hi tanpui turin an rawn kal a ni.

Take-Home Thuchah a ni

Okay, chuvangin kan sawi tawh White Matter Disease chungchanga hriat reng tur awlsam tak tak thenkhat han thlir ila:

• Hei hi thluaka white matter tihchhiatna a ni , thluaka information kengtu "kawngpui" tihchhiatna ang mai a ni.
• Tar leh lung natna hlauhawmna (thisen sang, zunthlum, cholesterol, meizuk) nen a inzawm fo thin.
• A lan chhuah dân chu hriatrengna hloh, kal harsa, leh balance hloh te a ni thei .
• MRI scan hmanga hmuhchhuah a ni ber .
• Thil chhia tih tawh chu tihdanglam vek theih ni lo mah se, risk factors control leh symptoms enkawl hmangin condition hi enkawl theih a ni .
• He natna hi a zual zel tur venna atan hian thinlung hriselna enkawl hi a pawimawh hle.

Heng symptoms te hi i neih chuan, emaw, he thil chungchang hi hriat belh i duh chuan, doctor advice dil ngei ang che . Hlau suh, heng zawng zawngah hian a pawimawh ber chu thu dik hriat chian a, a tul anga hmalak hi a ni.

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