Kia ako tātou mō ngā toa iti e rua e hanga ana i ō tātou angaanga: ko ngā 'Osteoblast' me ngā 'Osteoclasts'!

Kua whakaarohia e koe ō wheua? He maha ā tātou whakaaro he mea kaha, he mea kore e rerekē. Engari ehara i te mea pēnā. He kiko ora ō tātou wheua, pērā i te toenga o ō tātou tinana. Kāore pea koe e whakaaro pēnā, engari kei te tipu tonu, kei te pakaru, kei te whakakapia, ehara i te mea mai i te tamarikitanga ki te pakeketanga anake, engari mō te toenga o ō tātou oranga! E rua ngā momo pūtau tino nui e āwhina ana i tēnei mahi whakamiharo e kiia ana ko ngā 'Osteoblast' me ngā 'Osteoclasts'. Me kōrero anō tātou mō ēnei e rua i tēnei rā, e tika ana?

Ko wai ngā 'Osteoblast'? He aha tā rātou mahi?

He whakarāpopototanga noa iho, ko ngā 'Osteoblast' ngā "Mason Jars" e hanga ana i ō tātou wheua. I ētahi wā ka kiia hoki ko ngā 'osteogenic cells'. Ko rātou ngā mea e whakapakari ana i ō tātou wheua, ā, ko rātou ngā mea e hanga ana i ngā wheua hou. E toru ngā mahi matua a ngā 'Osteoblast':

• Te hanga wheua hou (te hanganga wheua ).
• I a tātou e pakeke haere ana, arā, i a tātou e tipu haere ana mai i te tamarikitanga ki te pakeketanga, ka huri ō tātou wheua kia rite ki te āhua o tō tātou tinana, he tukanga e kiia nei ko te 'whakahou'.
• Te whakaora i ngā wheua ina whati, ina whati, ina whara rānei .

Whakaarohia, ina hiahia tetahi o ō tātou wheua kia tipu, kia whakarerekē i tētahi ara, kia ora rānei i muri i te whati, ka whakaohokia ēnei pūtau 'Osteoblast' e ngā tauhohenga matū i roto i tō tātou tinana, e ngā 'hormone' rānei. Kātahi ka huihui mai ēnei pūtau 'Osteoblast' ka hanga, ka tuku i tētahi ranunga motuhake e kiia nei ko te 'bone matrix' . Ko tēnei 'bone matrix' he mea hanga mai i ngā 'pūmua' pērā i te 'collagen' me te 'calcium' me te 'phosphate', he kohuke tino nui ēnei mō ō tātou wheua. He rite tēnei mahi ki te tangata e ringihia ana te 'concrete' i te wā e hanga ana i tētahi rori. Ka taea e ia te hanga i tētahi rori hou. Ka taea rānei e ia te whakamahi i taua 'concrete' anō hei whakakī i ngā kapiti me ngā pakaru o tētahi rori tawhito. Waihoki, ka whakamahia e ngā 'Osteoblast', arā, ngā 'Mason', tēnei 'bone matrix' 'concrete' hei hanga wheua hou, hei whakapakari i ngā mea tawhito, hei whakaora i ngā mea whati. I muri i te hanganga o te kiko wheua hou i tēnei ara, ka noho ētahi pūtau 'Osteoblast' hei wāhanga o taua wheua hou. Kātahi ka kiia rātou ko ngā 'Osteocytes' . Ki te kore, ina kore e hiahiatia ā rātou ratonga, ka mate aua pūtau.

Me ako tātou mō ērā e kiia nei ko ngā 'Osteocytes'?

He rite ngā osteocyte ki ngā "kaitiaki haumaru" i roto i ō tātou wheua.Pēnei. Ko te nuinga o ō tātou wheua he mea hanga mai i ēnei pūtau 'Osteocytes'. Kei te mātakitaki tonu rātou i te momo pēhanga, i te pēhanga rānei e pā ana ki ō tātou wheua. Ina hikoi tātou, ina oma, ina hiki rānei i tētahi mea, ahakoa he pānga nui pēnei i te whati wheua, ka rongo ēnei 'Osteocytes' i taua mea. I taua wā, ko rātou te hunga e tuku tohu ana ki ngā 'Osteoblast' (te hunga e hanga ana) me ngā 'Osteoclasts' (te hunga e whati ana - ka kōrerohia e tātou i muri mai) me te kī, "Anei tētahi raruraru, haere mai ki te whakatika." Hei tauira, ki te pakaru, ki te whati rānei tētahi wheua, ko ngā 'Osteocytes' te hunga e tere kawe mai i ētahi atu pūtau ki te rohe, ka tango i ngā wahi pakaru, ka āwhina ki te hanga wheua hou me te whakaora.

Nā, he aha te momo pūtau he 'Osteoclasts'?

Ko ngā osteoclasts te "rōpū horoi" e whakarewa ana, e tango ana hoki i ngā pūtau tawhito, kua pakaru mai i ō tātou wheua. He rite ki te rōpū whakahoro. Ko rātou te hunga e whai wāhi ana ki ngā osteoblasts ki te hanga wheua hou.

He māmā noa iho te maumahara: He rite ngā 'pahū' ki ngā 'Kaihanga', he rite ngā 'Parāoa' ki ngā 'Kaihoroi'.

Ka tukuna e ngā osteoclast ngā whākōkī motuhake. Ka whakarewahia, ka wahia hoki e ēnei whākōkī te wheua tawhito. Ka puta he tauhohenga matū ki te mata o te kiko wheua tawhito, ka whakarewahia aua kongakonga, ka hanga huarahi mō ngā kiko hou, kaha ake. Engari ina whakarewahia ngā wheua e ngā osteoclast, ehara i te mea he waikawa e kai ana i tētahi wahi whakarewa pērā i te pakiwaituhi. He tino whakahaeretia, he tika hoki tēnei tukanga . Ka whakarewahia noa e ngā osteoclast ngā wāhi kua tohua e ngā osteocyte (āpiha haumarutanga) kua whakahuatia ake nei hei "koinei te wāhi me tango e tātou." Ka pakaruhia e ngā whākōkī e tukuna ana e ngā osteoclast te matrix wheua kaha, ka mimiti anō i ōna ihirangi. Kātahi ka puta he poka iti ki te mata o te wheua. Kia oti aua poka te hanga, ka haere mai ngā osteoblast (kaihanga) ka whakakī i ngā āputa ki te wheua hou. He rite ki te mahi tahi!

He aha te āhua o ēnei pūtau 'Osteoblasts' me 'Osteoclasts'?

He tino iti ēnei pūtau e rua, ā, kei roto i te uhi o waho ('arai wheua') o ō tātou wheua, me roto hoki i ngā wheua.

• He iti te nuinga o ngā pūtau osteoblast , he āhua tapawhā te āhua.
• He nui ake ngā wheua wheua i ngā wheua wheua. He porowhita, he rite ki te porowhita te āhua.

He aha ngā mate e pā ana ki te mahi a ēnei pūtau?

He wāhanga tino nui o ō tātou wheua ngā osteoblast me ngā osteoclast. Nō reira, ko ngā mate katoa e pā ana ki ō tātou wheua ka pā ki te mahi a ēnei pūtau. Anei ētahi o ngā raruraru matua e kore ai e taea e ō tātou wheua te hanga me te pupuri i te kaha:

• Te Osteoporosis - Koinei te wā ka angiangi, ka ngoikore, ka whati ngāwari ngā wheua.
• Osteopenia - He tohu tēnei mō te osteoporosis. Ka tīmata te heke o te mātotoru o ngā wheua.
• Hyperparathyroidism - He nui rawa te hanga o ngā homoni e ngā repe parathyroid, ka ngaro te konupūmā mai i ngā wheua.
• 'Te mate a Paget o te wheua (osteitis deformans)' - I tēnei āhua, ka raru te tukanga whakatikatika wheua, ka ngoikore, ka pēhia hoki ngā wheua.

He whakamātautau motuhake kei reira hei rapu mōhiohio mō ēnei pūtau?

Kāore he whakamātautau motuhake hei tirotiro i te pai o te mahi a ō osteoblast, osteoclast rānei. Ko te tikanga, ka whakamātauhia e ngā tākuta te hauora o te wheua katoa, kaua ki te titiro ki ngā pūtau motuhake. Heoi, i ētahi wā, ka mahia pea ngā whakamātautau toto (taiwhanga) hei tirotiro i te pai o te mahi a ō osteoclast, hei āwhina rānei i te tautuhi i tētahi mate pēnei i te osteoporosis. Anei ētahi whakamātautau noa hei tirotiro i te hauora o ō wheua:

• Whakamātautau kiato wheua (matawai DXA) : Ka whakamahia e tēnei he hihi-X iti hei ine i te kaha o ō wheua. Ka taea e ia te āwhina ki te whakatau mēnā kei te angiangi ō wheua i a koe e pakeke haere ana, mēnā rānei kei a koe ngā tohu o te osteopenia, te osteoporosis rānei.
• Whakamātautau Huaora D (`Whakamātautau Huaora D 25-hydroxy`) : Ka tirohia mēnā kei te whiwhi koe i te nui o te `Huaora D`.
• Whakamātautau konupūmā : Mā tēnei ka tirohia te taumata o te konupūmā i roto i tō toto, ā, ka taea hoki te tirotiro i te nui o te konupūmā i roto i tō mimi 24-hāora.
• Whakamātautau 'Te homoni parathyroid koretake (IPTH)' : Ka tirohia ngā taumata o te homoni parathyroid.
• Whakamātautau Creatinine : Mā tēnei ka tirohia mēnā kei te mahi tika ō whatukuhu.

Me aha tātou kia ora tonu ai ō tātou wheua?

He maha ngā mea ka taea e koe te mahi hei pupuri i te hauora me te kaha o ō wheua. Anei ētahi mea ka taea e koe te mahi:

• Kai i ngā kai totika me ngā matūkai , inā koa ngā kai e nui ana te konupūmā me te huaora D.
• Whakakorikori tinana e amo ana i te taumaha . Arā, ko te whakakorikori tinana e whakakaha ana i ō wheua, pērā i te hikoi , te oma, me te piki arawhata.
• Kaua rawa e kai hikareti . He tino kino te kai hikareti ki ngā wheua.
• Kia nui te konupūmā me te huaora D.Kia tūpato mēnā kei te rawaka āu kai. Ki te tika, me tango ngā tāpiringa i raro i te tohutohu a te tākuta.
• Me tirotiro hauora i ia wā . Ki te pāngia koe e te mate, e te panoni rānei, me toro atu ki te tākuta tonu.

He aha te rerekētanga i waenga i ngā 'Osteoblast' me ngā 'Osteocytes'?

He pūtau ngā 'Osteoblast' me ngā 'Osteocytes' e āwhina ana ki te hanga me te pupuri i ō tātou wheua. Engari he rerekētanga iti.

• Ko ngā osteoblast ngā pūtau e hanga ana i te wheua hou, e whakatipu ana i te wheua o mua, ā, e whakatika ana. Ko rātou ngā pūtau e tuku ana i te anga wheua me te hanga kiko hou.
• Ko ngā osteocyte he pūtau kei roto i te kiko wheua kua pakeke . Ko rātou ngā mea e rongo ana i te pēhanga me te ahotea ki runga i ngā wheua, ka tuku tohu ki ngā osteoblast me ngā osteoclast, me te kī, "He raruraru tēnei, me whakatika."

Hei whakamutunga, ngā mea hei maumahara (Karere hei tango ki te kāinga)

Kua mārama koe inaianei ki te pānga nui o ēnei pūtau iti e rua e kiia nei ko ngā 'Osteoblast' me ngā 'Osteoclasts' ki te hauora o ō tātou wheua. Ka mahi tahi tonu rāua, ka āwhina i ō tātou wheua kia tipu, kia whakahoutia, kia mau tonu te kaha. Pēnei i ngā toa kāore i te mōhiotia.

He mea nui rawa atu tēnei mō te hunga neke atu i te 65 tau te pakeke, ngā wāhine kua pāngia e te menopause, me te hunga he mate pūmau te rapu tohutohu hauora me te tirotiro hauora i ia wā. Mā tēnei ka taea e ngā tākuta te aroturuki i te hauora o ō wheua me te kite i ngā tohu wawe o te ngaronga o te wheua, te osteoporosis rānei.

Nō reira, tiakina hoki ō wheua. Ko te kai pai, te whakakori tinana, me te noho ora pai ngā mea tino nui!