Acromegaly: Kodi miyendo ndi nkhope yanu ndi zazikulu kwambiri? Tiyeni tikambirane!

Kodi munayamba mwazindikirapo kuti mawonekedwe a manja, miyendo, kapena nkhope yanu akusintha? Mwina mphete yomwe mumavala nthawi zambiri imamveka yolimba, kapena kukula kwa nsapato zanu kwasintha? Izi sizinthu zachisawawa chabe, zitha kukhala zizindikiro za matenda osowa koma omwe angakhale oopsa otchedwa acromegaly . Musadandaule, tikambirana izi mwatsatanetsatane komanso lero.

Kodi Acromegaly ndi chiyani? Mwachidule...

Acromegaly ndi vuto lomwe limayamba chifukwa cha kuchuluka kwa mankhwala otchedwa Growth Hormone (GH) m'thupi lanu. Kawirikawiri, hormone iyi (GH) imapangidwa ndi pituitary gland , yomwe ndi gland yofanana ndi nandolo pansi pa ubongo wathu. Komabe, mu acromegaly, hormone iyi imapangidwa mopitirira muyeso chifukwa cha chotupa mu pituitary gland kapena kwina kulikonse m'thupi.

Kodi mukudziwa kuti pituitary gland ndi kachiwalo kakang'ono koma kofunikira kwambiri. Kamatulutsa mahomoni asanu ndi atatu, limodzi mwa iwo ndi hormone ya kukula (GH).

Kodi hormone ya kukula (GH) ndi chiyani kwa ife?

Hormone Yokulira, yomwe imadziwikanso kuti Human Growth Hormone (hGH) kapena Somatotropin , ndi homoni yachilengedwe. Ndi yofunika kwambiri pakukula kwa ziwalo zosiyanasiyana za thupi lathu komanso kukula kwa msinkhu wathu tili ana. Komabe, pamene tikukula, mafupa athu atatsekedwa, matupi athu amafunikirabe GH iyi. Kodi mukudziwa chifukwa chake? Imathandiza kusunga kapangidwe kabwino ka mafupa athu, cartilage, ndi ziwalo zamkati, komanso imathandizira kuwongolera kagayidwe kachakudya, makamaka kuchuluka kwa shuga m'magazi.

Choncho, ngati hormone ya kukula kwa thupi (GH) imawonjezeka kwambiri munthu akakula, mavuto monga kufooka kwa mafupa, kukulitsa ziwalo, komanso kuchuluka kwa shuga m'magazi (hyperglycemia) angachitike.

Kodi kusiyana pakati pa Acromegaly ndi Gigantism ndi kotani?

Zonsezi zimachitika chifukwa cha kuwonjezeka kwa mahomoni okula (GH). Komabe, kusiyana kuli pa omwe matendawa amakhudza. Akuluakulu amadwala acromegaly. Ana amadwala gigantism .

Ngati kuchuluka kwa mahomoni okulira (GH) kukwera mwa ana asanatseke ma growth plates m'mafupa awo (monga, asanafike msinkhu), amakula modabwitsa. Izi zimatchedwa gigantism. N'zosowa kwambiri kuposa acromegaly. Madokotala ena amatchanso "pediatric acromegaly."

Komabe, ngati kuchuluka kwa mahomoni anu okula (GH) kukukwera pambuyo poti ma growth plates anu atsekedwa, simungakule kwambiri. Komabe, mahomoni ochulukirapo amenewo angakhudze mawonekedwe a mafupa anu, kukula kwa ziwalo zanu, ndi zina zokhudzana ndi thanzi. Matendawa amatchedwa acromegaly.

Ndani amene ali ndi mwayi waukulu wopeza matenda a acromegaly?

Zitha kuchitika pa msinkhu uliwonse mutakula msinkhu. Komabe, madokotala nthawi zambiri amazindikira matendawa mwa anthu azaka zapakati pa 40 ndi 50, kutanthauza kuti, azaka zapakati.

Kodi izi ndizofala bwanji?

Matenda a Acromegaly ndi matenda osowa kwambiri . Anthu pafupifupi 31 pa 100,000 okha ndi omwe apezeka ndi matendawa. Choncho musachite mantha mopanda chifukwa, koma ndikofunikira kudziwa zizindikiro zake.

Kodi acromegaly imakhudza bwanji thupi langa?

Munthu wamkulu akayamba kudwala matenda a acromegaly, kutanthauza kuti, akamakula mahomoni (GH), mafupa, cartilage, ziwalo za thupi, ndi minofu ina zimayamba kukula. Pali kusintha koonekeratu pa maonekedwe . Mwachitsanzo:

• Kukulitsa manja ndi mapazi.
• Kukulitsa makutu, milomo, ndi mphuno.
• Nsagwada yotuluka, mphumi yokulirapo.

Homoni yokulira (GH) imauza chiwindi chathu kuti chipange homoni ina yotchedwa Insulin-like Growth Factor 1 (IGF-1) . Homoni iyi, yotchedwa IGF-1, imathandiza mafupa ndi minofu yathu kukula, komanso imakhudza momwe thupi lathu limalamulira shuga m'magazi (shuga) ndi mafuta (lipids). Chifukwa chake, milingo ya GH ikakwera, milingo ya IGF-1 imawonjezekanso. Izi zingayambitse matenda monga Matenda a Shuga a Mtundu Wachiwiri , Kuthamanga kwa Magazi (Kuthamanga kwa Magazi) , ndi Matenda a Mtima .

Tangoganizani, monga momwe pompo yomwe imasiyidwa nthawi yayitali imatayira madzi, mahomoni awa, akakwera kwambiri, amakhala ndi zotsatira zosiyanasiyana pa thupi.

Kodi ndi zifukwa ziti zomwe zimayambitsa acromegaly?

Choyambitsa chachikulu cha acromegaly ndi chotupa mu pituitary gland. Ichi chimatchedwa pituitary adenoma . Chotupachi chimapangitsa pituitary gland kutulutsa mahomoni ochulukirapo (GH).

Zambiri zokhudza Pituitary Adenoma...

Matenda a pituitary adenomas nthawi zambiri amakhala abwino. Izi zikutanthauza kuti, si khansa. Zotupa zambiri zomwe zimayambitsa acromegaly zimakula pang'onopang'ono. Chifukwa chake, simungazindikire zizindikiro zilizonse za GH yochulukirapo kwa zaka zambiri.

Kutengera kukula ndi malo a chotupacho, chingakanikizidwe mbali zina za pituitary gland ndikukhudza mahomoni ena opangidwa ndi pituitary gland. Ngati chotupacho ndi chachikulu, chingakanikizidwenso mbali zapafupi za ubongo, zomwe zimayambitsa mutu ndi mavuto a masomphenya .

Kodi zizindikiro za Acromegaly ndi ziti?

Munthu wamkulu akayamba kudwala matenda a acromegaly, amakhudza mafupa ndi minofu ya thupi, zomwe zimapangitsa kuti akule modabwitsa. Izi zingayambitse zizindikiro zotsatirazi:

• Manja kapena mapazi okulira: Mwina mphete zanu zimayamba kulimba, ndipo kukula kwa nsapato zanu, makamaka m'lifupi, kumawonjezeka.
• Kusintha kwa mawonekedwe a nkhope: Kutuluka kapena kukulira kwa dera la nsagwada ndi/kapena pamphumi.
• Kukula kwa milomo, mphuno, ndi/kapena lilime.
• Thukuta kwambiri kapena khungu lamafuta.
• Kukweza mawu ndi kukweza mawu.

Zizindikiro zina:

• Mutu
• Kupweteka kwa mafupa
• Kusintha kwa masomphenya
• Kuwonjezeka kwa zizindikiro zazing'ono za pakhungu
• Kusanza m'manja
• Kupuma movutikira (sleep apnea)
• Matenda a Carpal tunnel kapena mavuto a msana.

Zizindikiro za acromegaly nthawi zambiri zimayamba pang'onopang'ono , nthawi zina pakapita zaka zambiri. Chifukwa chake zimakhala zovuta kuzizindikira poyamba. Anthu ena amangozindikira kuti manja awo akukula pamene mphete yomwe amavala yayamba kulimba kapena kukula kwa nsapato zawo kumasintha.

Tangoganizani, pali munthu dzina lake Nilanthi. Wakhala akumva ngati mphete yake yaukwati yathina kwa kanthawi tsopano. Nsapato zake sizili zolimba monga kale, zathina pang'ono. Amaganiza kuti wakula kumene. Koma nthawi yomweyo, anzake akunena kuti nkhope yake yasintha pang'ono kuposa kale, ndipo chibwano chake chakulirapo pang'ono. Izi ndi zinthu zazing'ono zomwe zimawonedwa koyamba.

Ngati muli ndi zizindikiro izi, ndikofunikira kwambiri kulankhula ndi dokotala.

Kodi matenda a acromegaly amachiritsidwa bwanji?

Chifukwa zizindikiro zimawonekera pang'onopang'ono kwambiri, pakapita zaka zambiri, zimakhala zovuta kuzizindikira.

Dokotala wanu angakutumizireni kwa katswiri wa matenda a endocrinologist , dokotala yemwe ndi katswiri wa matenda okhudzana ndi mahomoni. Iye adzakudziwitsani matendawo kutengera mbiri yanu yachipatala, mayeso azachipatala, ndi mayeso apadera (monga mayeso a magazi ndi mayeso ojambula zithunzi).

Kodi mayeso oyezetsa matenda ndi ati?

Ngati mwapezeka ndi acromegaly, dokotala wanu angakupatseni mayeso ena kuti aone ngati vutoli lakhudza ziwalo zina za thupi lanu. Izi zingaphatikizepo:

• Kuyezetsa kwa echocardiogram kuti muwone ngati pali mavuto a mtima.
• Kuyesa kuphunzira za kugona kuti muwone ngati mukupuma movutikira mukamagona.
• Colonoscopy kuti muwone thanzi la m'matumbo.
• Yesani thanzi la mafupa pogwiritsa ntchito X-ray kapena DEXA scan .

Kodi Acromegaly imachiritsidwa bwanji?

Pali njira zingapo zochizira matenda a acromegaly. Kutengera ndi zizindikiro ndi matenda anu, dokotala wanu adzakupatsani chithandizo choyenera kwa inu.

Mankhwala omwe amagwiritsidwa ntchito kwambiri ndi awa:

• Opaleshoni
• Mankhwala
• Chithandizo cha radiation

Opaleshoni ya Acromegaly

Nthawi zambiri, opaleshoni imatha kuchepetsa kapena kuchiritsa kwathunthu zizindikiro za acromegaly. Madokotala nthawi zambiri amagwiritsa ntchito njira yotchedwa transsphenoidal surgery , yomwe imaphatikizapo kuchita opaleshoniyo kudzera mu mphuno ndi kudzera mu sphenoid sinus (malo opanda kanthu kumbuyo kwa mphuno, pansi pa ubongo).

Tsatanetsatane wa opaleshoniyi umadalira kukula ndi malo a chotupacho. Cholinga chachikulu cha opaleshoniyi ndikuchotsa chotupa chonse chomwe chimayambitsa kupanga mahomoni ochulukirapo (GH). Ngati dokotalayo atha kuchotsa gawo lalikulu la chotupacho, simungafunike chithandizo china chilichonse. Komabe, ngati gawo lokha la chotupacho lachotsedwa, mungafunike mankhwala kapena chithandizo cha radiation kuti muchepetse zizindikiro ndikuchepetsa kupanga mahomoni okulirapo (GH).

Mankhwala a Acromegaly

Dokotala wanu angakupatseni mankhwala amodzi kapena kuphatikiza mankhwala. Mankhwalawa amagwira ntchito m'njira zosiyanasiyana kuti achepetse kuchuluka kwa mahomoni okulira m'thupi lanu (GH) ndikuchepetsa zizindikiro. Nthawi zina, mankhwalawa amaperekedwa mpaka chotupacho chitachepa, kuti dokotala wa opaleshoni athe kuchichotsa mosamala. Anthu ena angafunike kumwa mankhwala kwa nthawi yayitali kuti achepetse kuchuluka kwa mahomoni okulira (GH) ndi zizindikiro zake.

Kodi acromegaly ingachiritsidwe kwathunthu?

Acromegaly nthawi zina imatha kuchiritsidwa, koma osati nthawi zonse. Pamene chotupa cha pituitary chomwe chimayambitsa acromegaly chachotsedwa opaleshoni, chiŵerengero cha machiritso chimakhala pafupifupi 85% pa zotupa zazing'ono . Pa zotupa zazikulu, zimakhala pakati pa 40% ndi 50%.

Mankhwala sangachiritse matenda a acromegaly kwathunthu, koma angapereke chithandizo chotetezeka komanso cha nthawi yayitali .

Kodi acromegaly ingapewedwe?

Mwatsoka, palibe chomwe mungachite kuti mupewe acromegaly. Asayansi sakudziwabe chomwe chimayambitsa zotupa za pituitary zomwe zimayambitsa acromegaly. Komabe, amakhulupirira kuti zinthu zina za majini zitha kukhala ndi gawo.

Kodi acromegaly ndi chiyani?

Chiyembekezo cha izi chimadalira kuopsa kwa matendawa komanso momwe zizindikiro zimathetsedwera ndi chithandizo. Anthu ambiri amaona kuchepa kwakukulu kwa zizindikiro pambuyo pa chithandizo.

Ngati sichinachiritsidwe, acromegaly ingasinthe kwambiri mawonekedwe anu ndi mawonekedwe a mafupa anu. Zizindikirozi zitha kukhudza kwambiri kudzidalira kwanu komanso moyo wanu wabwino. Magulu othandizira amathandiza anthu ena kuthana ndi mavuto a acromegaly.

Acromegaly ingayambitsenso mavuto azaumoyo, monga matenda a mtima kapena matenda a shuga amtundu wa 2, zomwe zingachepetse moyo ndikufupikitsa nthawi yoyembekezera kukhala ndi moyo. Chifukwa chake, ndikofunikira kuwona dokotala ngati muli ndi zizindikiro ndipo, ngati mwapezeka ndi matendawa, kutsatira dongosolo la chithandizo mosamala.

Ndi mavuto otani omwe angachitike ngati sanachiritsidwe?

Ngati sichinachiritsidwe, acromegaly ingayambitse mavuto monga:

• Matenda a shuga amtundu wachiwiri
• Kuthamanga kwa magazi (BP)
• Matenda a mtima
• Matenda a minofu ya mtima (Cardiomyopathy)
• Matenda a nyamakazi
• Ma polyps a m'matumbo - Izi zimatha kukhala khansa ngati sizikuchiritsidwa.
• Kulephera kwa ziwalo

Kodi munthu amene ali ndi matenda a acromegaly amakhala ndi moyo wautali bwanji?

Izi zimadalira kuopsa kwa matendawa komanso ngati pali matenda ena, omwe nthawi zambiri amayamba chifukwa cha acromegaly yosachiritsidwa.

Ngati kuchuluka kwa mahomoni anu okulira (GH) sikuyendetsedwa bwino ndipo muli ndi matenda ena monga matenda a mtima ndi matenda a shuga, moyo wanu ukhoza kuchepetsedwa ndi zaka pafupifupi 10.

Komabe, ngati muli ndi acromegaly, mwalandira chithandizo choyenera, komanso muli ndi mahomoni okhwima (GH) ndi IGF-1, mwina mudzakhala ndi moyo wabwinobwino.

Kodi ndiyenera kupita liti kwa dokotala pankhani ya acromegaly?

Ngati muli ndi zizindikiro za acromegaly, ndikofunikira kwambiri kulankhula ndi dokotala.

Ngati mwapezeka ndi acromegaly, muyenera kupita kwa dokotala nthawi zonse kuti muwonetsetse kuti chithandizo chanu chikugwira ntchito bwino.

Acromegaly ndi matenda osowa koma oopsa. Nkhani yabwino ndi yakuti amatha kuchiritsidwa ndi opaleshoni, mankhwala, ndi/kapena chithandizo cha radiation. Ngati mwazindikira kuti manja, mapazi, ndi/kapena nkhope yanu ikukulirakulira, lankhulani ndi dokotala wanu. Akhoza kuchita mayeso ochepa osavuta kuti aone ngati kuchuluka kwa mahomoni anu okulira (GH) ndi komwe kumayambitsa zizindikiro zanu.

Pomaliza, uthenga wopita nawo kunyumba

• Acromegaly ndi vuto losowa kwambiri mwa akuluakulu lomwe limayamba chifukwa cha kuchuluka kwa mahomoni okula (GH).
• Zizindikiro zake zingaphatikizepo kutupa kwa miyendo ndi nkhope, thukuta kwambiri, komanso kusintha kwa mawu . Izi zingawonekere pang'onopang'ono, kotero simungazizindikire.
• Chifukwa chachikulu cha izi ndi chotupa, chomwe nthawi zambiri sichili khansa, chomwe chimayamba mu pituitary gland.
• Kuzindikira msanga ndi kulandira chithandizo kungateteze mavuto ambiri ndikukweza moyo.
• Ngati muli ndi zizindikiro izi, musazengereze kufunafuna upangiri wa dokotala. Ndicho chinthu chanzeru kwambiri kuchita.

Kumbukirani, izi ndi zongopereka chidziwitso chokha. Siziyenera kugwiritsidwa ntchito m'malo mwa upangiri wa zachipatala. Ngati muli ndi nkhawa zilizonse zokhudza thanzi lanu, chonde funsani katswiri wazachipatala wodziwa bwino ntchito yanu.

Acromegaly , Hormone Yokula, Pituitary Gland, Gigantism, IGF-1, Matenda a Hormonal, Endocrine