Kodi muli ndi vuto lochepa la maselo oyera m'magazi? Tiyeni tiphunzire za Autoimmune Neutropenia (AIN)!

Kodi munayamba mwadzifunsapo chifukwa chake chitetezo chathu chamthupi, m'malo motiteteza, nthawi zina chimayamba kuukira maselo athu? Imeneyo ndi vuto lovuta koma lomveka bwino lotchedwa Autoimmune Neutropenia (AIN) . Chomwe chimachitika ndichakuti chitetezo chathu chamthupi chimaukira mtundu wofunika kwambiri wa maselo oyera m'thupi lathu, otchedwa `neutrophils.` Tiyeni tikambirane izi mosavuta, m'njira yomwe mungamvetse.

Ndiye, kodi Autoimmune Neutropenia (AIN) ndi chiyani?

Mwachidule, `Autoimmune Neutropenia` (AIN) ndi matenda okhudzana ndi magazi. Chomwe chimachitika apa ndi chakuti chitetezo chathu cha mthupi, chomwe chiyenera kutiteteza, chimaukira molakwika maselo athu oyera amagazi otchedwa `neutrophils`. Tangoganizirani izi, monga gulu lankhondo loteteza dziko lathu molakwika likuukira anthu athu.

Kodi 'Neutrophils' ndi chiyani?

Ma neutrophils ndi mbali yofunika kwambiri ya chitetezo chathu chamthupi. Ali ngati asilikali ang'onoang'ono m'thupi lathu. Ntchito yawo yaikulu ndikupeza ndikuwononga zinthu zovulaza zomwe zimalowa m'thupi, monga mabakiteriya ndi bowa zomwe zimayambitsa matenda. Chifukwa chake, pankhani ya `Autoimmune Neutropenia`, chitetezo chathu chamthupi chimawononga maselo ofunika awa a `neutrophils`, kotero chiwerengero cha `neutrophils` m'magazi chimachepa pansi pa mulingo wabwinobwino.

Pali mitundu iwiri ikuluikulu ya AIN:

1. Matenda Oyambitsa Matenda a Autoimmune Neutropenia (AIN): Izi nthawi zambiri zimawoneka mwa makanda ndi ana aang'ono . Chomwe chimachitika apa ndichakuti chiwerengero cha `neutrophils` chimachepa popanda chifukwa china chilichonse. Koma nkhani yabwino ndi yakuti vutoli nthawi zambiri limatha pakatha zaka zingapo.

2. Matenda a Secondary Autoimmune Neutropenia (AIN): Izi zimachitika kwambiri mwa ana okalamba ndi akuluakulu . Pano, kuchuluka kwa ma neutrophil ochepa kumachitika chifukwa cha matenda ena. Mwachitsanzo, kungayambitsidwe ndi matenda, matenda ena a magazi, kapena matenda ena a autoimmune (matenda omwe chitetezo cha mthupi chimaukira thupi lake). Matenda a secondary AIN nthawi zambiri amakhala osatha .

Kodi chiwerengero cha ma neutrophils chotchedwa neutropenia n'chochepa bwanji?

Matenda a Autoimmune Neutropenia ndi mtundu umodzi wa matenda ambiri otchedwa Neutropenia. Neutropenia imagawidwa m'magulu ofatsa, apakati, kapena ovuta, kutengera kuchuluka kwa ma neutrophils pa microliter (microL) ya magazi.

• Kuchepa kwa Neutropenia: 1,000 - 1,500 ma neutrophils pa microL iliyonse.
• Neutropenia yapakati: 500 - 1,000 neutrophils pa microL iliyonse.
• Matenda a Neutropenia Oopsa: Ma Neutrophils osakwana 500 pa microL iliyonse.

Chofunika kwambiri ndichakuti mfundo izi ziyenera kutsimikiziridwa ndi dokotala. Ngati muli ndi kukayikira kulikonse pa izi, ndikofunikira kwambiri kufunafuna upangiri wa dokotala.

Kodi AIN imakhudza bwanji thupi langa?

Mmene AIN imakukhudzirani zingasiyane malinga ndi munthu. Zimatengera zinthu zingapo, choncho ndi bwino kulankhula ndi dokotala wanu za izi. Ngati kuchuluka kwa ma neutrophil anu kumatsika kwambiri, mumakhala ndi mwayi wopeza matenda . Nthawi zina matendawa akhoza kukhala oopsa, makamaka ngati simulandira chithandizo chamankhwala mwachangu.

Komabe, nthawi zina, matenda a autoimmune neutropenia angayambitse matenda ofooka okha. Kapena akhoza kukhala opanda zizindikiro. Ndicho chifukwa chake ndikofunikira kugwira ntchito ndi dokotala kuti mudziwe chomwe chikuyambitsa matenda anu a neutropenia. Kutengera ndi chomwe chikuyambitsa, dokotala wanu akhoza kuyang'anira vuto lanu ndikukuthandizani kuwongolera matendawa.

Ndani amadwala matenda a Autoimmune Neutropenia (AIN)?

• AIN Yoyamba: Izi zimakhudza kwambiri makanda ndi ana aang'ono . Nthawi zambiri zimapezeka ali ndi miyezi 8.
• AIN yachiwiri: Izi zimachitika nthawi zambiri ndi matenda ena odziteteza okha, monga lupus kapena rheumatoid arthritis. Ana omwe ali ndi AIN yachiwiri nthawi zambiri amapezeka ali ndi zaka 10. Akuluakulu omwe ali ndi AIN nthawi zambiri amapezeka ali ndi zaka zapakati pa 40 ndi 60.

Kodi autoimmune neutropenia ndi yofala bwanji?

Matenda a AIN oyamba ndi matenda osowa kwambiri . Amakhudza mwana m'modzi yekha mwa ana 100,000 osakwana zaka 10. Kotero mutha kuwona momwe zimakhalira zachilendo.

Kodi zizindikiro za Autoimmune Neutropenia ndi ziti?

Matenda a Autoimmune Neutropenia nthawi zambiri samayambitsa zizindikiro zazikulu. Komabe, nthawi zina mungaone zizindikiro za matenda. Mwachitsanzo:

• Matenda a m'makutu: Ichi ndi chimodzi mwa zizindikiro zofala kwambiri. Tangoganizirani kuti mwana wanu akuvutika ndi ululu wa m'makutu nthawi zonse, ndipo mukapita kwa dokotala, amakuuzani kuti ndi matenda ena a m'makutu.
• Matenda opatsirana m'mapapo: Chimfine, chifuwa, ndi malungo nthawi zambiri.
• Matenda a pakamwa: Zinthu monga zilonda pakamwa ndi gingivitis.
• Matenda a pakhungu.
• Chibayo.
• Matenda a meninjitisi.
• Matenda a mkodzo (UTIs).
• Sepsis: Ichi ndi matenda oopsa kwambiri, omwe amaika moyo pachiswe.

Matenda okhudzana ndi AIN yoyamba nthawi zambiri amakhala ochepa, koma matenda oopsa monga chibayo, meningitis, ndi sepsis amapezeka kwambiri mu AIN yachiwiri.

Kodi n’chiyani chimayambitsa matenda a autoimmune neutropenia?

AIN imagawidwa ngati yoyamba kapena yachiwiri kutengera chifukwa cha kuchuluka kwa ma neutrophil otsika.

Matenda Oyambitsa Matenda a Autoimmune Neutropenia (AIN Yoyamba)

Mu AIN yoyamba, ma antibodies amalimbana ndi kuwononga ma neutrophils. Ma antibodies ndi mtundu wa mapuloteni omwe ali mu chitetezo chathu chamthupi. Ntchito yawo yanthawi zonse ndi kuwononga zinthu zovulaza, monga mavairasi ndi mabakiteriya, omwe amalowa m'thupi. Koma pakadali pano, ofufuza sakudziwabe chifukwa chake ma antibodies athu amaukira ma neutrophils awa.

Matenda a Sekondale a Autoimmune Neutropenia (Sekondale AIN)

Mu AIN yachiwiri, chiwerengero cha ma neutrophils chimachepa chifukwa cha chifukwa china kapena vuto lina. Izi zimapangitsa kuti chitetezo cha mthupi chiwononge ma neutrophils.

Zinthu zina zomwe zingayambitse izi ndi izi:

• Matenda ena a autoimmune: Zitsanzo ndi monga nyamakazi, lupus, ndi autoimmune hemolytic anemia.
• Khansa: Mwachitsanzo, `large granular lymphocyte leukemia`.
• Matenda: Matenda monga `HIV`, `Parvovirus`, `hepatitis B`.
• Zotupa: Monga `Chotupa cha Wilms`, `Matenda a Hodgkin`.
• Matenda a mitsempha: Mwachitsanzo, multiple sclerosis.
• Kusamutsa impso kapena mafupa.
• Mankhwala ena: Makamaka mankhwala ena a chemotherapy omwe amaperekedwa chifukwa cha khansa.

Kodi matenda a Autoimmune Neutropenia amapezedwa bwanji? (Kuzindikira)

Mukakhala ndi malungo kapena matenda, dokotala wanu angaone kuti kuchuluka kwa ma neutrophil anu ndi kochepa panthawi yoyezetsa magazi kuti adziwe chomwe chikuyambitsa. Kuzindikira AIN kungakhale kovuta pang'ono, chifukwa pali zifukwa zambiri zomwe zingachitike. Dokotala wanu angazindikire AIN atachotsa matenda ena omwe angayambitse kuchuluka kwa ma neutrophil anu.

Kuti adziwe kapena kuyang'anira `Autoimmune Neutropenia`, dokotala wanu angachite mayeso otsatirawa:

• Kuchuluka kwa magazi (CBC): CBC imatha kuwona kuchuluka kwa ma neutrophils m'magazi anu. Popeza milingo iyi imatha kusiyana, dokotala wanu nthawi zambiri amachita ma CBC opitilira limodzi kuti atsimikizire neutropenia ndikuwunika milingo yanu ya ma neutrophil. Ma CBC wamba angathandizenso kudziwa ngati AIN yanu ndi yosatha.
• Kuyeza magazi m'mbali mwa thupi: Kuyeza magazi kumayesedwa pogwiritsa ntchito maikulosikopu kuti aone mawonekedwe ndi mtundu wa ma neutrophils. Izi zimathandizanso pozindikira matenda.
• Mayeso a Vitamini B12, folate, ndi copper: Mayeso awa amatha kuwona kusowa kwa michere iyi. Thupi limafunikira izi kuti lipange ma neutrophils.
• Mayeso a ntchito ya chiwindi: Izi zitha kuwonanso momwe chiwindi chikuyendera komanso ngati pali matenda a chiwindi omwe ali ndi kachilombo.
• Kafukufuku wa HIV ndi mavairasi ena: Matenda opatsirana ndi mavairasi monga HIV angayambitsenso kuchepa kwa maselo oyera a magazi.
• Kuyeza kwa kayendedwe ka magazi: Iyi ndi njira yoyezera maselo kuti aone ngati ali ndi zizindikiro za matenda. Imagwiritsidwa ntchito kudziwa ngati neutropenia imayamba chifukwa cha vuto la autoimmune.
• Kujambula: Ngati pali kukayikira kuti AIN imayambitsidwa ndi khansa monga lymphoma, MRI kapena CT scan ikhoza kuchitidwa.
• Kufufuza ndi kuyeza kuchuluka kwa mafuta m'mafupa: Apa, dokotala amatenga chitsanzo cha mafuta m'mafupa ndikuwunika ngati pali zizindikiro za matenda. Izi zingathandize kudziwa ngati neutropenia imayambitsidwa ndi khansa ya m'magazi, monga khansa ya m'magazi.

Dokotala wanu angakupatseninso mayeso a magazi kuti muwone ngati pali ma antibodies m'magazi anu omwe amaukira ma neutrophils. Mayeso ofala kwambiri ndi I-GIFT (Indirect granulocyte immunofluorescence test) ndi GAT (Granulocyte agglutination test).

Mwatsoka, mayesowa nthawi zonse samakhala odalirika pozindikira AIN. Kutengera ndi chifukwa cha neutropenia yanu komanso nthawi yoyesera, mayesowa sangazindikire ma antibodies kapena angapereke zotsatira zabodza. Zotsatira zabodza ndi pamene mayesowo akuwonetsa kuti ma antibodies alipo pomwe palibe.

Ngati dokotala akuganiza kuti neutropenia imayamba chifukwa cha vuto linalake, akhoza kuyitanitsa mayeso ena.

Kodi matenda a Autoimmune Neutropenia amachiritsidwa bwanji?

Chithandizo chimadalira kuopsa kwa vuto lanu. Mwachitsanzo, mwana yemwe ali ndi neutropenia yosawonetsa zizindikiro angafunike kupatsidwa CBCs nthawi zonse ndi kuchuluka kwa neutrophils, koma sangafunike chithandizo mwachangu. Ngati mwana wanu ali ndi matenda opatsirana pafupipafupi, dokotala wanu angapereke mankhwala oletsa mabakiteriya kuti apewe matenda. Mankhwala oletsa mabakiteriya nthawi zambiri amaperekedwa kuti athetse matenda, koma mankhwala oletsa mabakiteriyawa amaperekedwa kuti apewe matenda.

Kwa munthu amene ali ndi AIN yachiwiri, dokotalayo adzachiza vuto lomwe limayambitsa kuchepa kwa neutrophil. Angakuuzeninso kuti:

• Granulocyte colony-stimulating factor (G-CSF): Iyi ndiyo njira yaikulu yothandizira matenda oopsa a neutropenia. Imathandiza thupi kupanga ma neutrophils ambiri. G-CSF imathanso kupewa matenda opatsirana pafupipafupi okhudzana ndi AIN yoyamba.
• Corticosteroids: Corticosteroids, monga prednisone, imaletsa chitetezo cha mthupi lanu, kuchepetsa kuchuluka kwa ma antibodies omwe amaukira ma neutrophils.
• Mankhwala ena: Mankhwala ena monga IVIG, rituximab, ndi alemtuzumab agwiritsidwanso ntchito kwa odwala omwe ali ndi matenda oopsa a autoimmune neutropenia.

Kodi Autoimmune Neutropenia ikhoza kupewedwa?

Palibe AIN yoyamba kapena AIN yachiwiri yomwe ingapewedwe . Komabe, mutha kupewa mavuto okhudzana ndi `Autoimmune Neutropenia`, kutanthauza kuti, kukula kwa matenda. Kuti muchite izi, muyenera kuchitapo kanthu kuti mudziteteze ku matenda. Mwachitsanzo, kupewa malo odzaza anthu, kusamba m'manja pafupipafupi, komanso kupewa anthu odwala.

Kodi munthu amene ali ndi matenda a Autoimmune Neutropenia angayembekezere tsogolo lotani?

AIN yoyamba nthawi zambiri imadzithera yokha . Pafupifupi 95% ya ana omwe ali ndi AIN, kuchuluka kwa neutrophil m'magazi awo kumabwerera mwakale akafika zaka ziwiri kapena zitatu. Pafupifupi ana onse omwe ali ndi AIN yoyamba amachira mokwanira akafika zaka 11. Izi n'zolimbikitsa kwambiri, sichoncho?

Nthawi zina, yotchedwa secondary AIN, kuchira kwanu kumadalira zinthu zingapo, makamaka vuto lomwe linayambitsa neutropenia yanu. Kuchiza vutoli ndikupewa matenda kungathandize kubwezeretsa kuchuluka kwa ma neutrophil anu kukhala kwabwinobwino.

Kodi ndiyenera kupeza upangiri wa dokotala liti?

Ngati muli ndi vuto lalikulu la autoimmune neutropenia ndipo mukuyamba kutentha thupi, pitani kwa dokotala nthawi yomweyo . Nthawi zina, dokotala wanu akhoza kukupatsani mankhwala opha tizilombo toyambitsa matenda kuti mumwe ngati mukuyamba kutentha thupi. Nthawi zambiri, muyenera kulandira chithandizo kuchipatala.

Ngati muli ndi matenda oopsa a autoimmune neutropenia omwe amatenga nthawi yayitali, dokotala wanu adzakufotokozerani zizindikiro zomwe muyenera kudziwa komanso zomwe mungachite kuti mupewe mavuto.

Kumbukirani: Ngati inu kapena mwana wanu mwapezeka ndi AIN, lankhulani ndi dokotala wanu za momwe imakukhudzirani. Ngakhale zizindikiro ndi zomwe zimayambitsa zimasiyana, nkhani yabwino ndi yakuti mankhwala monga G-CSF ndi othandiza kwambiri pakuwonjezera kuchuluka kwa neutrophil.

Ngati mwana wanu ali ndi AIN, pitani kukayezetsa magazi nthawi zonse monga momwe dokotala wanu wanenera. Yang'anirani zizindikiro za matenda, ndipo funani chithandizo mwamsanga ngati muwona chilichonse, kuti mupewe mavuto omwe angakhalepo.

Chidule (Uthenga Wopita Nawo Kunyumba)

Chabwino, ndikukhulupirira kuti tsopano mwamvetsa bwino za `Autoimmune Neutropenia` (AIN) yomwe tidakambirana.

• AIN ndi vuto lomwe chitetezo chathu cha mthupi chimawononga maselo athu oyera a magazi otchedwa `neutrophils`.
• Izi zitha kuchitika mwa ana aang'ono (Primary AIN) kapena akuluakulu (Secondary AIN). Primary AIN mwa ana aang'ono nthawi zambiri imatha yokha.
• Chiwopsezo chachikulu ndi matenda opatsirana pafupipafupi.
• Pali mayeso a magazi ndi mayeso ena oti azindikire.
• Chithandizo chimaphatikizapo kuyang'aniridwa, mankhwala oletsa matenda, G-CSF, ndi corticosteroids.
• Chofunika kwambiri ndichakuti musamachite mantha kapena kuchita mantha ndikupempha upangiri kwa dokotala ngati inu kapena mwana wanu muli ndi zizindikirozi. Ngati mwapezeka msanga ndikuthandizidwa bwino, mutha kukhala ndi moyo wathanzi ngakhale muli ndi AIN.

Ngati muli ndi mafunso ena okhudza izi, onetsetsani kuti mwalankhula ndi dokotala wanu. Iwo ndi omwe angakupatseni upangiri wabwino kwambiri.

Neutropenia , Autoimmune Neutropenia, Maselo Oyera a M'magazi, Chitetezo cha Mthupi, Matenda, Matenda a M'magazi, Matenda a Ana