Tiyeni tiphunzire za mankhwala a matenda a shuga monga Canagliflozin ndi Metformin.

Kodi muli ndi matenda a shuga, kapena matenda a shuga a mtundu wachiwiri? Kapena kodi pali munthu amene mumamudziwa amene ali ndi vutoli? Ndiye dokotala wanu mwina anakupatsani mankhwala osakaniza awiri, omwe ndi Canagliflozin ndi Metformin, makamaka mapiritsi otulutsa mankhwala kwa nthawi yayitali . Dzina la mankhwalawa likhoza kukhala Invokamet XR. Tiyeni tikambirane zambiri za mankhwalawa lero, sichoncho?

Kodi kwenikweni chimachitika ndi mankhwala awa ndi chiyani?

Mwachidule, mankhwalawa amagwiritsidwa ntchito powongolera kuchuluka kwa shuga m'magazi mwanu (shuga m'magazi) . Mukakhala ndi `Matenda a Shuga a Mtundu Wachiwiri`, pamakhala kusintha kwina m'mene thupi lathu limawongolera shuga. Mankhwalawa amagwira ntchito pochepetsa kuchuluka kwa shuga m'magazi ndikukuthandizani kukhala ndi thanzi labwino. Pankhaniyi, `Canagliflozin` imathandiza thupi kutulutsa shuga wochuluka kudzera mu mkodzo, pomwe `Metformin` imachepetsa kupanga shuga ndi chiwindi ndikuwonjezera mphamvu ya maselo a thupi ku insulin. Koma kumbukirani, mankhwalawa okha sikokwanira. Zakudya zabwino komanso masewera olimbitsa thupi ndizofunikira kwambiri pa izi.

Kodi ndi zinthu ziti zomwe muyenera kuuza dokotala wanu musanamwe mankhwalawa?

Izi ndizofunikira kwambiri. Ngati muli ndi vuto lililonse mwa zotsatirazi, muyenera kuuza dokotala wanu musanayambe kumwa mankhwalawa. Chifukwa, pokhapokha dokotala angasankhe ngati mankhwalawa ndi oyenera kwa inu kapena ayi, kapena ngati mlingo wake uyenera kusinthidwa. Tangoganizani, ngati simunauze dokotala izi, mungakumane ndi mavuto osafunikira.

• Ngati muli ndi 'Anemia'
• Ngati muli ndi matenda a mitsempha yamagazi
• Ngati mwataya madzi m'thupi chifukwa cha kusowa madzi
• Ngati mudadwalapo kale matenda a shuga otchedwa `Diabetic ketoacidosis (DKA)` (kuchuluka kwa asidi m'magazi chifukwa cha matenda a shuga)
• Ngati mudya zakudya zopanda mchere wambiri
• Ngati mukudya pang'ono chifukwa cha matenda, opaleshoni, kuchepetsa kudya, kapena zifukwa zina
• Ngati muli ndi zilonda za mapazi
• Ngati mukuchitidwa opaleshoni mtsogolo
• Ngati muli ndi matenda a mtima
• Ngati muli ndi cholesterol yambiri (`cholesterol yambiri`)
• Ngati potaziyamu m'magazi ndi wokwera (`Potaziyamu wambiri m'magazi`)
• Ngati mwendo kapena gawo lina la thupi lanu linachotsedwapo kale ('Mbiri ya kudulidwa kwa chiwalo')
• Ngati muli ndi mbiri ya matenda a kapamba kapena mavuto ena a kapamba wanu
• Ngati muli ndi mbiri ya matenda a yisiti m'mimba kapena m'chikazi
• Ngati mumamwa mowa nthawi zonse
• Ngati mukupeza matenda m'chikhodzodzo, impso, kapena njira ya mkodzo
• Ngati muli ndi matenda a impso (mankhwalawa si oyenera ngati ntchito ya impso ili pansi pa mulingo winawake)
• Ngati muli ndi matenda a chiwindi
• Ngati muli ndi kuthamanga kwa magazi kotsika (`Kuthamanga kwa magazi kotsika`)
• Ngati muli ndi vuto la mitsempha
• Ngati ndinu munthu amene akulandira chithandizo cha hemodialysis
• Ngati muli ndi vuto la `Polycystic ovary syndrome (PCOS)` (vuto lomwe ma cysts amapangika m'ma ovary)
• Ngati muli ndi vuto lokodza
• Ngati muli ndi matenda aakulu kapena kuvulala
• Ngati muli ndi matenda a shuga a mtundu wa 1 (mankhwala awa ndi a anthu omwe ali ndi matenda a shuga a mtundu wa 2)
• Ngati ndinu mwamuna wosadulidwa
• Ngati mukusanza pafupipafupi
• Ngati muli ndi vuto la ziwengo chifukwa cha Canagliflozin, Metformin, mankhwala ena, zakudya, utoto, kapena zosungira
• Ngati muli ndi pakati kapena mukufuna kutenga mimba
• Ngati ndinu mayi woyamwitsa (`woyamwitsa`)

Musachite mantha ndi mndandandawu. Si zonse zomwe zikugwira ntchito kwa aliyense. Koma ngati pali china chake chomwe chikukukhudzani, ndikofunikira kuti mudziwitse dokotala wanu kuti muli otetezeka .

Kodi ndiyenera kugwiritsa ntchito bwanji mankhwalawa?

Chabwino, tsopano tiyeni tiwone momwe tingagwiritsire ntchito mankhwalawa molondola.

• Muyenera kumwa piritsi ili ndi kapu ya madzi .
• Izi ziyenera kumwedwa ndi chakudya . Nthawi zambiri ndi chakudya choyamba cha tsikulo. Kapena monga momwe dokotala wanu wanenera.
• Mezani piritsi lonse . Musaliphwanye kapena kulitafuna. Izi zili choncho chifukwa lapangidwa kuti ligwire ntchito kwa nthawi yayitali. Ngati muliphwanya, mankhwalawo adzalowa m'thupi lanu nthawi yomweyo, zomwe zimapangitsa kuti shuga m'magazi muchepe mwadzidzidzi kapena mavuto ena.
• Imwani mankhwala omwe mwapatsidwa, panthawi yolembedwa, mu mlingo womwe mwapatsidwa, monga momwe zalembedwera pa chizindikiro cha mankhwala.
• Musamwe mowa woposa womwe dokotala wakupatsani, kapena kumwa mowa pafupipafupi.
• Musasiye kumwa mankhwala mwadzidzidzi popanda upangiri wa dokotala. Kuchita zimenezi kungapangitse kuti shuga m'magazi mwanu mukwere mwadzidzidzi.

Mukalandira mankhwala awa kuchokera ku pharmacy, mudzapatsidwa kabuku kapadera kodziwitsa (ka `MedGuide`) pamodzi ndi mankhwalawo. Onetsetsani kuti mwawerenga mosamala nthawi iliyonse mukalandira mankhwala anu kapena mukalandira `refill`. Kali ndi zambiri zofunika kwa inu.

Kodi mankhwala awa angaperekedwe kwa ana?

Muyenera kulankhula ndi gulu lanu lazaumoyo pankhani yopereka mankhwalawa kwa ana. Nthawi zambiri mankhwalawa amaperekedwa kwa akuluakulu. Ngati akufunika kwa ana, amafunika zifukwa zapadera komanso kuyang'aniridwa.

Bwanji ngati mumwa mowa mopitirira muyeso? ('Kumwa mopitirira muyeso')

Ngati mukuganiza kuti mwamwa mankhwala ochulukirapo, pitani ku dipatimenti yadzidzidzi ya chipatala chapafupi nthawi yomweyo, kapena imbani malo owongolera poizoni (monga National Poisons Information Center - 0112 686 143) . Musataye nthawi.

Chofunika: Mankhwalawa aperekedwa kwa inu nokha. Musagawire mankhwala anu ndi ena, ngakhale atakhala ndi vuto lomwelo monga lanu. Chifukwa mankhwala omwe amagwira ntchito kwa munthu wina sangagwire ntchito kwa wina.

Kodi mungachite chiyani ngati mwaphonya mlingo wa mankhwala?

Nthawi zina mumalephera kumwa mankhwala. Ngati zimenezo zitachitika, imwani mwamsanga mukangokumbukira . Komabe, ngati nthawi yatsala pang'ono yoti mutenge mlingo wotsatira (monga, mkati mwa maola ochepa), dumphani mlingo womwe mwaphonya ndikumwa mlingo wotsatira panthawi yomwe mwakonza. Musamwe mlingo wowirikiza kawiri. Kuchita zimenezi kungapangitse kuti shuga m'magazi mwanu atsike kwambiri.

Ndi mankhwala ena ati omwe angagwirizane ndi mankhwalawa?

Iyi ndi mfundo yofunika kwambiri. Mukamamwa mankhwala a `Canagliflozin; Metformin`, sikoyenera kumwa mankhwala ena. Komanso, akhoza kusokonezana ndi mankhwala ena. Chifukwa chake, muyenera kuuza dokotala wanu za mankhwala onse omwe mukumwa (omwe dokotala wanu wakupatsani, omwe mumagula ku pharmacy, mankhwala achikhalidwe, mavitamini, ngakhale 'zowonjezera zakudya'). Komanso, uzani dokotala wanu ngati mumasuta ndudu, kumwa mowa, kapena kumwa mankhwala ena.

Mankhwala omwe sayenera kumwedwa ndi mankhwalawa:

• Mitundu ina ya mankhwala 'osiyana', omwe amaperekedwa kudzera m'mitsempha asanayesedwe mayeso ena monga X-ray, CT scans, ndi MRIs, amatha kukhudza impso ndipo, akaphatikizidwa ndi 'Metformin', amawonjezera chiopsezo cha matenda oopsa otchedwa 'Lactic Acidosis'.
• `Dofetilide` (uyu ndi mankhwala operekedwa pa kayendedwe ka mtima kosasinthasintha).

Mankhwala ena omwe angagwirizane ndi mankhwalawa:

(Mndandanda uwu sungakhale wokwanira, choncho ndikofunikira kuuza dokotala wanu zonse zomwe mukumwa)

• `Acetazolamide`
• Mowa - Umawonjezera chiopsezo cha lactic acidosis ndipo ungayambitsenso shuga m'magazi.
• Mankhwala ena oletsa mavairasi a HIV kapena Hepatitis
• Mankhwala ena a kuthamanga kwa magazi, matenda a mtima, ndi matenda a mtima (monga beta-blockers, omwe angabise zizindikiro za shuga wotsika m'magazi)
• 'Cimetidine'
• `Dichlorphenamide`
• Digoxin (mankhwala a mtima) - Mlingo wa Digoxin ukhoza kusintha ukamwedwa ndi Canagliflozin.
• Mankhwala ochepetsa kukodza (mankhwala omwe amayambitsa kukodza kwambiri) - Amawonjezera chiopsezo cha kutaya madzi m'thupi komanso kuthamanga kwa magazi.
• Mahomoni a Estrogen kapena progestin
• `Glycopyrrolate`
• `Isoniazid` (mankhwala a chifuwa chachikulu)
• `Lamotrigine`
• `Lithium`
• `Memantine`
• 'Methazolamide'
• 'Metoclopramide'
• `Midodrine`
• `Niacin`
• `Phenobarbital`
• Mankhwala otchedwa phenothiazines (monga chlorpromazine, prochlorperazine, thioridazine)
• `Phenytoin`
• `Ranolazine`
• Rifampin (mankhwala ogwiritsidwa ntchito pochiza chifuwa chachikulu kapena matenda ena) - Angachepetse mphamvu ya Canagliflozin.
• `Ritonavir`
• Mankhwala a steroid (monga prednisone kapena cortisone) - amatha kukweza shuga m'magazi.
• Mankhwala olimbikitsa kuvutika maganizo, kuchepetsa thupi, kapena kukhala maso
• Mankhwala a chithokomiro
• `Topiramate`
• `Trospium`
• `Vandetanib`
• `Zonisamide`

Tangoganizirani, zinthu zambiri zingasinthe mphamvu ya mankhwalawa. Ndicho chifukwa chake ndikofunikira kwambiri kuuza dokotala wanu za mankhwala aliwonse omwe mumamwa .

Ndi zinthu ziti zomwe muyenera kusamala nazo mukamamwa mankhwalawa?

Mukamagwiritsa ntchito mankhwalawa, muyenera kusamala kwambiri za thanzi lanu.

• Pitani kwa dokotala wanu nthawi zonse ('macheke okhazikika') kuti muwone momwe mulili . Pezani mayeso monga momwe impso zimagwirira ntchito komanso kuchuluka kwa vitamini B12 monga momwe dokotala wanu akulangizira.
• Popeza mankhwalawa ali ndi `Metformin`, nthawi zina asidi m'magazi amatha kukhala oopsa kwambiri (`Lactic Acidosis`) . Ngakhale izi sizichitika kawirikawiri, zitha kukhala zoopsa kwambiri ngati zitachitika. Ngati mukumva zizindikiro monga nseru, kusanza, kupweteka m'mimba, kutopa kosazolowereka, kupuma movutikira, kupuma mofulumira, kumva kuzizira, kapena chizungulire, siyani kumwa mankhwalawa nthawi yomweyo ndikuitana dokotala wanu kapena pitani kuchipatala . Ngati n'kotheka, onaninso mkodzo wanu kuti muwone ngati muli ndi ma ketones pogwiritsa ntchito `ketone dipstick`.
• Canagliflozin ingayambitsenso matenda otchedwa Diabetic Ketoacidosis (DKA) . Uwu ndi mkhalidwe womwe shuga m'magazi sumakwera kwambiri. Zizindikiro zake ndi monga ludzu lochuluka, kukodza pafupipafupi, pakamwa pouma, kutopa, kupuma movutikira, kupuma movutikira, kupweteka m'mimba, nseru, ndi kusanza. Ngati mukukumana ndi zizindikiro izi, uzani dokotala wanu nthawi yomweyo.
• Dokotala wanu nthawi zambiri amalamula mayeso otchedwa `HbA1C (A1C)` kuti aone momwe shuga m'magazi mwanu akuyendetsedwera bwino . Iyi ndi mayeso osavuta amagazi. Ikhoza kusonyeza momwe shuga m'magazi mwanu wayendetsedwera bwino kwa miyezi 2-3. Mayesowa nthawi zambiri amachitika miyezi 3-6 iliyonse.
• Phunzirani momwe mungayesere kuchuluka kwa shuga m'magazi mwanu kunyumba . Komanso, dziwani zizindikiro za shuga wotsika m'magazi (hypoglycemia) ndi shuga wambiri m'magazi (hyperglycemia) ndi momwe mungathanirane nazo .
• Nthawi zonse khalani ndi shuga wochepa (monga ma cubes a shuga, mapiritsi a shuga, chakumwa chotsekemera, madzi a zipatso) ngati mukumva zizindikiro za shuga wochepa m'magazi (thukuta, kugwedezeka, njala yayikulu, kugunda kwa mtima mofulumira, chizungulire, kusokonezeka). Komabe, ngati mutakomoka kapena muli ndi khunyu , uzani achibale anu kuti akhoza kutsamwitsidwa ngati ayesa kukupatsani chakudya kapena chakumwa. Ngati izi zitachitika , muyenera kupita kuchipatala nthawi yomweyo .
• Mankhwalawa angachepetse kuchuluka kwa folic acid ndi vitamini B12 m'thupi lanu, makamaka ndi metformin. Chifukwa chake, onetsetsani kuti mwadya mavitamini okwanira mukamamwa mankhwalawa. Dokotala wanu angakupatseni vitamini yowonjezera ngati pakufunika kutero.
• Pewani kutaya madzi m'thupi . Imwani madzi ambiri, makamaka nyengo yotentha, mukamachita masewera olimbitsa thupi, kapena ngati muli ndi m'mimba.
• Samalani kwambiri mapazi anu . Yang'anani mapazi anu tsiku lililonse, chifukwa pali chiopsezo chochepa cha matenda kapena kudulidwa kwa miyendo ya m'munsi mukamagwiritsa ntchito mankhwalawa (makamaka Canagliflozin). Choncho ngati muli ndi mabala, ming'alu, kufiira, kapena kutupa pamapazi anu, uzani dokotala wanu nthawi yomweyo.

Kodi zotsatirapo zake zingakhale zotani chifukwa cha mankhwalawa?

Monga mankhwala ena aliwonse, mankhwalawa angayambitse zotsatira zina zoyipa. Koma si aliyense amene amawapeza. Ena ndi oopsa ndipo muyenera kuuza dokotala wanu nthawi yomweyo. Ena nthawi zambiri samakhala oopsa, koma ngati apitirira, ndi bwino kuuza dokotala wanu .

Zotsatirapo zomwe muyenera kuuza dokotala wanu nthawi yomweyo

• Matenda a ziwengo : ziphuphu pakhungu, kuyabwa, ziphuphu (matuza ofiira pakhungu), kutupa kwa nkhope, milomo, lilime, kapena pakhosi (kungayambitse kupuma movutikira).
• Kusowa madzi m'thupi : Kuwonjezeka kwa ludzu, pakamwa pouma, chizungulire, mutu, mkodzo wakuda wachikasu kapena bulauni, kuchepa kwa mkodzo.
• Matenda a shuga a ketoacidosis (DKA) : Ludzu lochuluka kapena kukodza, pakamwa pouma, kutopa kwambiri, mpweya wonunkhira ngati zipatso, kupuma movutikira, kupweteka m'mimba, nseru, ndi kusanza.
• Matenda a yisiti m'mimba : (mu nyini mwa akazi, mbolo mwa amuna) kufiira, kutupa, kupweteka kapena kuyabwa, fungo loipa, ndi kutuluka magazi koyera kokhuthala kapena kofiira.
• Kuchuluka kwa lactic acid m'magazi (`Lactic Acidosis`) : Kupweteka kwa minofu kapena kupweteka m'mimba, kupweteka m'mimba, kuvutika kupuma, kupuma mofulumira, kusapeza bwino komanso kutopa, chizungulire, kuzizira.
• Matenda ozungulira ziwalo zoberekera kapena m'dera lomwe limatsogolera ku anus (`Fournier's gangrene`) : kufiira, kutupa, kuuma, kapena kupweteka, nthawi zina ndi malungo. Uwu ndi matenda oopsa kwambiri, omwe amatha kupha, choncho uzani dokotala wanu nthawi yomweyo ngati muwona zizindikiro izi.
• Kuchepa kwa vitamini B12 : Ululu, dzanzi, kapena kutayika kwa kumva m'miyendo, kufooka kwa minofu, chizungulire, kuvutika kuyang'ana, kusokonezeka, lilime lopweteka, kusintha mtundu wa khungu.
• Kupweteka kapena kuuma kwatsopano kwa mwendo kapena phazi, kusintha kwa mtundu wa khungu, zilonda kapena zilonda, kapena matenda.Izi ndi zinthu zomwe ziyenera kuganiziridwa mwachangu.
• Matenda a mkodzo (UTI) : Kumva kutentha mukamakodza, kukodza pafupipafupi, mkodzo wokhala ndi magazi kapena mitambo, kupweteka m'munsi mwa msana kapena m'mimba, kutentha thupi.
• Kusweka kwa mafupa : Kafukufuku wina wasonyeza kuti chiopsezo cha kusweka kwa mafupa chikuwonjezeka pang'ono mwa anthu omwe akumwa Canagliflozin. Choncho samalani ndi kugwa.

Zotsatirapo zomwe nthawi zambiri sizifuna upangiri wa dokotala, koma ngati zikupitirira, muyenera kuuza dokotala wanu.

• Kutsegula m'mimba
• Gasi
• Mutu
• Kusanza
• Ululu wa M'mimba
• Kusanza
• Kuchuluka kwa kukodza pafupipafupi
• Ludzu lopitirira muyeso

Mndandandawu sungakhale ndi zotsatirapo zonse zoyipa. Ngati muwona china chake chachilendo, lankhulani ndi dokotala wanu. Muthanso kunena za zotsatirapo zoyipa ku FDA (Food and Drug Administration) pa 1-800-FDA-1088.

Kodi muyenera kusunga bwanji mankhwala anu?

Ndikofunikanso kwambiri kusunga mankhwala anu moyenera.

• Sungani pamalo omwe ana ndi ziweto sangafikire.
• Sungani kutentha kwa chipinda (pakati pa madigiri 15 ndi 30 Celsius, pakati pa madigiri 59 ndi 86 Fahrenheit). Tetezani ku chinyezi chochuluka komanso kuwala kwa dzuwa mwachindunji. Musasunge m'malo onyowa kwambiri, monga m'bafa.
• Musagwiritse ntchito mankhwala otha ntchito. Tayani.

Kodi mumataya bwanji mankhwala osagwiritsidwa ntchito komanso omwe atha ntchito?

• Ngati n'kotheka, perekani mankhwalawa ku pulogalamu yoti mutenge mankhwala. Mutha kudziwa zambiri za malo otere ku pharmacy yanu kapena ndi akuluakulu azaumoyo am'deralo.
• Ngati sichoncho, yang'anani chizindikiro chomwe chili pa botolo/paketi ya mankhwala kuti muwone ngati ayenera kutayidwa mu zinyalala kapena kutayidwa m'chimbudzi. Ngati simukudziwa, funsani dokotala wanu kapena wamankhwala.
• Ngati mungathe kuutaya mu zinyalala (zomwe zimachitika nthawi zambiri), tulutsani mankhwalawo mu chidebecho, sakanizani ndi chinthu chomwe palibe amene angadye, monga khofi wogwiritsidwa ntchito, dothi, kapena zinyalala za amphaka, ndikuyika mu thumba kapena chidebe chotseka ndikuchitaya mu zinyalala. Izi ndi kuletsa wina kutenga mankhwalawo ndikugwiritsa ntchito.

Uthenga Wopita Nawo Kunyumba

Chabwino, takambirana zambiri za mankhwala a matenda a shuga `Canagliflozin` ndi `Metformin`. Mwachidule:

• Uwu ndi mankhwala ofunikira a matenda a shuga a mtundu wachiwiri omwe amayang'anira shuga m'magazi .
• Zotsatira zabwino kwambiri zimapezeka ngati izi ziphatikizidwa ndi zakudya komanso masewera olimbitsa thupi.
• Onetsetsani kuti mwauza dokotala wanu za matenda ena aliwonse omwe muli nawo komanso mankhwala ena aliwonse omwe mukumwa.
• Monga momwe dokotalayo adanenera,Imwani mlingo wolembedwa, panthawi yolembedwa, pamodzi ndi chakudya . Mezani piritsi lonse.
• Dziwani zizindikiro za shuga wotsika m'magazi (hypoglycemia) ndipo sungani shuga pafupi kuti mugwiritse ntchito mukafuna.
• Ngati mukukumana ndi zizindikiro zachilendo (makamaka zizindikiro zomwe zingakhale za `DKA` kapena `Lactic Acidosis`, matenda opatsirana m'mimba (chiopsezo cha `Fournier's gangrene`), zilonda za miyendo, zizindikiro za kutaya madzi m'thupi), uzani dokotala wanu nthawi yomweyo.
• Lumikizanani ndi dokotala wanu ndipo mukambirane za vuto lanu. Musaope kufunsa mafunso.

Kumbukirani, mankhwalawa ndi othandiza pochepetsa matenda anu a shuga. Thanzi lanu limadalira kwambiri moyo wanu, zakudya zanu, komanso kutsatira malangizo a dokotala wanu. Mankhwalawa sachiza matenda a shuga, amangothandiza kuwaletsa.

Ngati muli ndi mafunso ena, musazengereze kufunsa dokotala wanu, wamankhwala, kapena wothandizira zaumoyo wina. Iwo alipo kuti akuthandizeni.

Canagliflozin , Metformin, Invokamet XR, Matenda a Shuga a Mtundu wa 2, Matenda a Shuga, Shuga wa M'magazi, Mankhwala a Shuga, Zotsatirapo Zake