Kodi inunso mumakumana ndi matenda a Alzheimer's akamakula msanga? Tiyeni tiphunzire za matendawa!

Kodi nthawi zina mumaganiza kuti, "O, ndikuiwala chilichonse masiku ano"? Kapena mwaona kusintha pang'ono m'maganizo kapena machitidwe a mnzanu? Mwina zinthu izi si chinthu chodetsa nkhawa nazo. Komabe, ngati zinthuzi zikupitirirabe kuchitika ngakhale musanakule, ndi bwino kuzifufuza pang'ono. Kumva zinthuzi kungakhale kosokoneza pang'ono, koma chofunika kwambiri ndikudziwa izi.

Kodi Matenda a Alzheimer Oyambirira Ndi Chiyani?

Mwachidule, Matenda a Alzheimer Oyamba Kubadwa (EOAD) ndi mtundu wa matenda a Alzheimer omwe amafalikira mwa anthu osakwana zaka 65. Madokotala nthawi zina amatcha matenda a Alzheimer oyambira ali aang'ono . Nthawi zambiri, zizindikirozi zimayamba kuonekera pakati pa zaka 45 ndi 64.

Matenda a Alzheimer's ndi matenda omwe amawononga mitsempha . Ndiko kuti, ndi matenda omwe amawononga ndikuwononga maselo muubongo wathu pakapita nthawi. Ichi ndiye chifukwa chachikulu cha matenda a dementia , omwe ndi kutayika pang'onopang'ono kwa kukumbukira ndi nzeru. Komabe, odwala onse a Alzheimer's ochepera 1% amadwala matenda a dementia oyambirira (EOAD).

Poyamba, mungakhale ndi nthawi yovuta kuzindikira kusintha komwe kulipo mwa inu. Koma anthu omwe ali pafupi nanu, monga banja lanu ndi anzanu, angazindikire kusintha kochepa komwe simungazindikire. Ngati muwona kusintha kulikonse mu kukumbukira kwanu, kuganiza kwanu, kapena magwiridwe antchito anu atsiku ndi tsiku, pitani kwa dokotala nthawi yomweyo.

Kodi zizindikiro za matenda a Alzheimer's oyambirira ndi ziti?

Zizindikiro za matenda a Alzheimer omwe analipo kale zimafanana kwambiri ndi za matenda a Alzheimer's wamba. Kusiyana kwakukulu ndi msinkhu womwe zizindikirozi zimayamba kuonekera. Matendawa amachititsa kuchepa pang'onopang'ono kwa luso la nzeru (kuchepa kwa chidziwitso) . Izi zikutanthauza kuti pamene ubongo ukuwonongeka, zizindikirozo zimakula pakapita nthawi.

Poyamba, zingakuvuteni kuzindikira nokha zizindikirozi. Koma okondedwa anu, banja lanu, angazindikire kusinthaku pang'ono. Ngati inu kapena munthu amene mumamudalira awona zizindikiro zilizonse za matenda amisala, ndikofunikira kwambiri kulankhula ndi dokotala.

Matendawa (EOAD) sakhudza aliyense mofanana. Koma kawirikawiri, angakhudze:

• Kukumbukira
• Luso la chilankhulo - kulankhula ndi kulemba
• Luso loganiza bwino
• Khalidwe ndi umunthu
• Kudziwa za malo - Mwachitsanzo, kumvetsetsa za malo.

(EOAD) Zizindikiro nthawi zambiri zimayamba pang'ono kwambiri ndipo zimakula pakapita nthawi. Poyamba, mungaone kusintha pang'ono monga:

• Kusintha kwa khalidwe lanu kapena umunthu wanu (makamaka kukhala wokwiya msanga, wosinthasintha maganizo, kapena wosinthasintha maganizo kuposa kale)(Zingachuluke.) Tangoganizirani, munthu amene kale anali wodekha kwambiri tsopano akukwiya ndi zinthu zazing'ono.
• Kuvuta kupeza mawu oyenera polankhula kapena polemba. Zimakhala ngati mawu sakutuluka mkamwa mwanu.
• Kutaya kukumbukira (monga kuiwala mayina a anthu, nkhope, kapena zochitika zomwe zinachitika panthawiyo). Kodi nthawi zambiri mumaiwala mndandanda wa zinthu zomwe munauzidwa kuti mubweretse? Kapena mumaiwala mwadzidzidzi zomwe munkafuna kunena pokambirana?
• N'zovuta kuthetsa mavuto omwe nthawi zambiri mumatha kuchita mosavuta.
• Ngakhale malangizo aperekedwa (monga kuphika motsatira njira yophikira) , zingakhale zovuta kuyang'ana kwambiri zomwe mungachite kenako ndikupanga zisankho .
• Mavuto ndi masomphenya, kulinganiza bwino, ndi kugwirizana (mungadzipeze mukungogundana ndi mipando nthawi zonse kapena kupunthwa).

Pambuyo pake, mungaone zizindikiro zoopsa kwambiri, monga:

• Kuyiwala komwe muli komanso momwe munafikira kumeneko .
• Choyipa kwambiri ndi kutayika kwa kukumbukira (mpaka kufika poti umaiwalanso mbali zina za kukumbukira kwa nthawi yayitali).
• Kukayikira ndi kusakhulupirira okondedwa anu (ngakhale omwe mukuti mumawadziwa bwino).
• Kutaya pang'ono (kapena kwathunthu) kwa luso lolankhula ndi kulankhulana.

Kodi ndi zifukwa ziti zomwe zimayambitsa matenda a Alzheimer's oyambirira?

Chifukwa chachikulu cha matenda a Alzheimer's msanga ndi kusungidwa kosazolowereka kwa mapuloteni muubongo , makamaka mitundu iwiri ya mapuloteni otchedwa amyloid ndi tau .

Mukudziwa, ubongo wathu uli ndi maselo amitsempha mabiliyoni ambiri otchedwa ma neuron . Maselo amitsempha awa ndi omwe amatithandiza kuganiza, kuphunzira, kukumbukira, ndi kukonzekera. Chifukwa chake, puloteni ya amyloid imalumikizana mkati mwa maselo a ubongo, ndikupanga ma clumps otchedwa ma plaque . Mapuloteni a Tau amalumikizana pamodzi, kupanga ma tangles . Ma plaque ndi ma tangles awa amaletsa maselo amitsempha kugwira ntchito bwino. Amaletsa zizindikiro zamagetsi ndi mankhwala zomwe zimadutsa mwa iwo.

Pamene mapuloteni a amyloid ndi tau akuunjikana mu ubongo, pang'onopang'ono amapha maselo a mitsempha. Izi ndi zomwe zimayambitsa kuwonongeka kosatha komwe kumayambitsa zizindikiro za matenda a Alzheimer's. Maselo a mitsempha amayamba kufa mbali imodzi ya ubongo, kenako n'kufalikira mbali zina. Nthawi zambiri, EOAD imayamba mbali ya ubongo yomwe imayang'anira kukumbukira kwathu - hippocampus .

Akatswiri akuyesetsabe kupeza chifukwa chake mapuloteniwa amaunjikana. Ofufuza akuganiza kuti kuchulukana kwa mapuloteni kumeneku kumachitika kale zizindikiro zisanawonekere. Zingatenge zaka 10 kuti muyambe kuona zizindikiro.

Kodi matenda a Alzheimer's amayamba msanga ndi majini?

Inde, matenda a Alzheimer's asanakwane ndi matenda a majini.N'zotheka. Matenda ambiri a (Early-Onset Alzheimer's disease ) apezeka kuti akugwirizana ndi kusintha kwa majini mu ma chromosome 1, 14, kapena 21. Komanso, kukhala ndi jini yotchedwa (APOE e4 gene) kumawonjezera chiopsezo. Koma si aliyense amene ali ndi jini ya (APOE e4) amene adzadwala Alzheimer's. Ndi chinthu chimodzi chokha chomwe chingawonjezere chiopsezo.

Matenda a Alzheimer's amathanso kuchitika m'mabanja. Izi zikutanthauza kuti ngati makolo anu kapena abale anu ali ndi matendawa, muli pachiwopsezo chachikulu chotenga matendawa. Ngati abale anu awiri kapena makolo anu onse ali nawo, chiopsezo chanu chimakhala chachikulu kwambiri.

Kodi zinthu zoopsa ndi ziti?

Ofufuza akufufuzabe zomwe zimayambitsa matenda a Alzheimer's kukula msanga kuposa msinkhu uwu. Zina mwa zinthu zomwe zingawopseze matendawa ndi izi:

• Kukhala ndi matenda a Alzheimer's mwa achibale apafupi (makolo, abale).
• Zinthu zokhudzana ndi chilengedwe (chinachake chomwe chili m'malo omwe mumakhala, mumagwira ntchito, kapena nthawi zambiri).
• Kuvulala kwambiri mutu (kuvulala koopsa muubongo) .
• Kusuta fodya.
• Thanzi lanu lonse.

Matenda ena amatha kuwonjezera chiopsezo cha matenda a Alzheimer's, kuphatikizapo:

• Matenda a mtima
• Matenda a shuga
• Matenda a Down omwe amayamba chifukwa cha (Trisomy 21)
• Kuthamanga kwa magazi
• Cholesterol yambiri
• Kunenepa kwambiri

Kodi mavuto a Alzheimer's omwe amayamba msanga ndi ati?

Vuto lalikulu la matenda a Alzheimer's omwe amayamba msanga ndi kuwonongeka komwe kumayambitsa ubongo wanu. Kungayambitse kusintha kosatha kwa momwe mumaganizira, momwe mumagwiritsira ntchito thupi lanu, komanso umunthu wanu. Pamene matendawa akupita patsogolo, mungakumane ndi mavuto, ena mwa iwo omwe angakhale oopsa.

Izi zitha kuwonedwa ngati zovuta:

• Kuwonongeka kwa thanzi la thupi lonse.
• Matenda (monga chibayo kapena matenda a pakhungu).
• Kugwidwa ndi khunyu .
• Kuvuta kupuma.
• Kuvuta kumeza.

Ngati simungathe kulamulira thupi lanu, mungakhale pachiwopsezo chachikulu cha:

• Zilonda za m'mimba .
• Kusowa madzi m'thupi kapena kusowa zakudya m'thupi .
• Kugwa, kusweka mafupa, ndi kuvulala kwina kwakukulu.
• Kulephera kudziletsa mkodzo ndi kusadziletsa m'mimba .
• Kuwola kwa mano, mabowo, ndi mavuto ena a mano.

Kodi matenda a Alzheimer's a Early-Onset amapezeka bwanji?

Madokotala amazindikira matenda a EOAD mofanana ndi momwe amadziwira matenda a Alzheimer's. Amachita kafukufuku wathunthu wa thupi ndi mayeso a mitsempha.Kenako, amachotsa matenda ena omwe angayambitse mavuto ofanana ndi kukumbukira ndi zizindikiro zina.

Dokotala wanu adzakufunsani mafunso kuti amvetse thanzi lanu komanso moyo wanu watsiku ndi tsiku. Adzakulankhulaninso za kusintha komwe simungazindikire, koma komwe munthu wapafupi nanu waona. Dokotala wanu angakufunseni za:

• Thanzi lanu lonse.
• Mbiri yanu yachipatala .
• Ndi mankhwala kapena zowonjezera ziti zomwe mukumwa pakadali pano?
• Kusintha kwa momwe mukumvera, khalidwe lanu, ndi umunthu wanu.
• Luso lanu lochita ntchito zanu zachizolowezi.

Dokotalayo adzachitanso mayeso angapo monga:

• Mayeso a kuzindikira .
• Kujambula kwa CT .
• Kujambula kwa MRI ya ubongo .
• Kujambula kwa PET .
• Kuyezetsa magazi.
• Kuyesa mkodzo.

Palibe mayeso amodzi omwe angatsimikizire kapena kuzindikira matenda a Alzheimer's omwe amayamba msanga. Komabe, ndi chidziwitso chosonkhanitsidwa kuchokera ku mayeso aliwonsewa, dokotala akhoza kuchotsa matenda ena omwe angayambitse zizindikiro zofanana.

Kodi mankhwala otani a matenda a Alzheimer's omwe amayamba msanga ndi ati?

Dokotala wanu adzakulangizani mankhwala ochepetsa kupitirira kwa matenda anu a dementia , omwe ndi kutayika kwa kukumbukira ndi nzeru. Palibe mankhwala a mtundu uliwonse wa matenda a Alzheimer's . Komabe, mankhwala angathandize kuwongolera zizindikiro ndikuchepetsa kupitirira kwa matendawa.

Kuyamba chithandizo mwamsanga ndiyo njira yabwino kwambiri yosungira thanzi la ubongo wanu m'moyo wanu wonse. Komabe, palibe chithandizo chomwe chingathandize kubwezeretsa kuwonongeka kwa ubongo kapena kuchepa kwa chidziwitso.

Dokotala wanu mwina adzakupatsani mankhwala ochiritsira matenda a Alzheimer's a EOAD. Mungafunike mankhwala monga awa:

• (Zoletsa za Cholinesterase)
• (Donanemab)
• (Lecanemab)
• (Otsutsa a NMDA)

Aducanumab ndi mankhwala atsopano a EOAD. Akatswiri akufufuzabe. Imachepetsa mapuloteni a amyloid omwe amasonkhana muubongo.

Mankhwala oletsa zizindikiro zinazake

Dokotala wanu angakulembereninso mankhwala oletsa zizindikiro zina. Mwachitsanzo:

• Mankhwala Oletsa Kuvutika Maganizo : Mankhwalawa amatha kuchiza zinthu monga nkhawa, kusakhazikika maganizo, kusintha kwa maganizo, komanso kuvutika maganizo.
• (Ma antipsychotics (neuroleptics)) : Izi zingayambitse mantha, kuona zinthu molakwika, komanso kusokonezeka maganizo.Zinthu ngati zimenezo zitha kuchiritsidwa.
• (Mankhwala oletsa kugunda kwa mtima) : Mankhwalawa nthawi zina amatha kuchiza kusinthasintha kwa maganizo.

Mayeso azachipatala

Asayansi nthawi zonse amafufuza za EOAD ndi mankhwala omwe angapezeke. Funsani dokotala wanu ngati pali mayesero aliwonse azachipatala omwe angakuthandizeni. Awa ndi mayeso kapena maphunziro omwe amakhudza odzipereka omwe ali ndi matenda a Alzheimer's oyambilira. Izi zingakupatseni mwayi woyesa mankhwala atsopano omwe sanapezeke kwambiri.

Kodi munthu amene ali ndi matenda a Alzheimer's amayembekezera moyo wautali bwanji?

Matenda a Alzheimer oyambilira msanga amakhudza aliyense mosiyana. Anthu ena amakhala ndi moyo kwa zaka zambiri. Ena amafa mkati mwa zaka 10 kuchokera pamene apezeka ndi matendawa. Kutalika kwa moyo wanu kumadalira zinthu monga:

• Kuchuluka kwa luso lanu la nzeru kukuchepa (kuchepa kwa nzeru) .
• Zaka zanu pamene munapezeka ndi matendawa.
• Thanzi lanu lonse ndi matenda ena aliwonse omwe mungakhale nawo.

Matenda a Alzheimer omwe amayamba msanga nthawi zambiri amakula mofulumira kuposa matenda a Alzheimer wamba. Izi zikutanthauza kuti mungakhale ndi zizindikiro zoopsa msanga kuposa momwe munthu wina angadziwire atakwanitsa zaka 65. Lankhulani ndi dokotala wanu za kukhala ndi matenda a Alzheimer omwe amayamba msanga (EOAD). Iye angakuthandizeni kukhazikitsa zolinga ndi ziyembekezo zenizeni.

Kodi mungatani kuti muzolowere kukhala ndi matenda a Alzheimer's oyambirira?

Kukhala ndi matenda a Alzheimer's omwe amayamba msanga kungakhale kovuta kwambiri. Anthu omwe amadwala matenda a Alzheimer's (EOAD) nthawi zambiri amakhala akugwirabe ntchito, ndipo akhoza kukhala ndi mabanja achichepere okhala ndi ana aang'ono . Izi zitha kubweretsa mavuto omwe anthu omwe ali ndi matenda a Alzheimer's omwe nthawi zonse sakhala nawo. Izi zitha kukhala zovuta kwambiri, koma kumbukirani kuti simuli nokha paulendowu.

Muli ndi ufulu wofunafuna chithandizo chomwe mukufuna kuntchito kwanu. Dokotala wanu angakuuzeninso za zinthu zina zomwe zingakuthandizeni. Mutha kuyamba kukonzekera zamtsogolo zizindikiro zanu zisanakule kwambiri. Mwachitsanzo, mungafune kuganizira malangizo apamwamba , mapulani azamalamulo ndi azachuma.

Ngati mukufuna thandizo, lankhulani ndi katswiri wa zamaganizo . N'zofala kwambiri kuti anthu omwe ali ndi matenda a Alzheimer omwe amayamba msanga komanso mabanja awo azikhala ndi nkhawa, nkhawa, komanso chisoni chowonjezereka , makamaka akapezeka ndi matendawa. Maganizo amenewo ndi enieni komanso olondola, koma safunika kulamulira moyo wanu. Katswiri wa zamaganizo angakuthandizeni kumvetsetsa malingaliro ndi malingaliro anu ndikukuthandizani kuthana nawo.

Kodi ndiyenera kupita kwa dokotala liti?

Ngati mukukumana ndi vuto lililonse ndi kukumbukira kapena kuganiza kwanu, pitani kwa dokotala nthawi yomweyo .

Muyenera kupita kukayezetsa dokotala nthawi zonse. Iye adzayang'anira momwe matenda anu akupitira patsogolo ndikusintha chithandizo chanu ngati pakufunika kutero.

Mukhozanso kufunsa dokotala wanu mafunso monga awa:

• Ndi zizindikiro kapena kusintha kotani komwe ine ndi banja langa tiyenera kuyang'anira?
• Kodi pali njira yodziwira momwe matendawa adzapitirire mofulumira?
• Kodi chithandizo chabwino kwambiri kwa ine ndi chiti?
• Kodi mungandipatse malangizo ena othandiza anthu ammudzi omwe angathandize banja langa kuti lizolowere vutoli?

Aliyense amaiwala zinthu zazing'ono nthawi ndi nthawi, kapena mwadzidzidzi amaiwala zomwe akufuna kunena akamalankhula. Si chinthu chodetsa nkhawa. Palibe amene amadziwa bwino maganizo ndi thupi lanu kuposa inu. Koma ngati mukuda nkhawa kuti kukumbukira kwanu kapena kuganiza kwanu kukusintha kwambiri—makamaka ngati zikuchitika mwadzidzidzi—onani dokotala.

Ndiye, ndi zinthu ziti zofunika kwambiri zomwe tikufuna kutenga kuchokera m'nkhaniyi?

Matenda a Alzheimer's Oyamba Kuyamba ndi vuto lalikulu lomwe lingakhudze anthu osakwana zaka 65. Ndikofunikira kwambiri kufunafuna upangiri wa dokotala nthawi yomweyo ngati muwona zizindikiro zoyambirira monga kuiwala, kuvutika kupeza mawu, ndi kusintha kwa khalidwe .

Ngakhale kuti palibe mankhwala a vutoli, kuzindikira matendawa msanga komanso kulandira chithandizo kungathandize kuchepetsa zizindikiro ndikuchepetsa kufalikira kwa matendawa. Kumbukirani kuti simuli nokha. Pali madokotala, akatswiri azaumoyo wamaganizo, ndi magulu othandizira omwe angakuthandizeni inu ndi banja lanu kuthana ndi vutoli.

Samalani thanzi la ubongo wanu. Ngati muwona kusintha kulikonse, musanyalanyaze.

` Alzheimer's, kuiwala, kukumbukira, matenda a ubongo, matenda a mitsempha, matenda a dementia, EOAD