Kodi muli ndi mafunso okhudza kuyezetsa magazi kwa ENA Panel (Extractable Nuclear Antigen Panel)? Tiyeni tikambirane mwachidule!

Kodi mudamvapo kuti chitetezo cha thupi lathu, asilikali omwe akuyenera kutiteteza ku matenda, amalakwitsa ndikuyamba kuukira ziwalo zathu zathanzi? Izi ndi zomwe timatcha matenda odziteteza okha . Pazochitika zotere, mayeso apadera a magazi otchedwa ENA panel angakuthandizeni kudziwa vuto lenileni komanso chifukwa chake izi zikuchitika. Lero, tiyeni tikambirane za ENA Panel , yomwe imayimira Extractable Nuclear Antigen Panel , m'njira yosavuta yomwe mungamvetse, chabwino?

Kodi mayeso a ENA ndi chiyani kwenikweni?

Mwachidule, gulu la ENA ndi mayeso a magazi. Limafufuza ngati chitetezo chathu cha mthupi chikuyesera kuukira ziwalo zathanzi za thupi lathu. Tsopano tiyeni tifotokoze pang'ono izi. Chitetezo chathu cha mthupi chili ngati gulu lankhondo lomwe limateteza dziko. Mu gulu lankhondo ili, muli asilikali apadera, omwe timawatcha ma antibodies . Ntchito ya ma antibodies awa ndikuzindikira ndikulimbana ndi tizilombo toyambitsa matenda , monga mabakiteriya ndi mavairasi, omwe amalowa m'thupi. Mdani aliyense ali ndi chizindikiro chapadera pathupi lake chomwe chingachizindikire, chomwe timatcha antigen mu mankhwala. Kotero ma antibodies amazindikira antigen iyi ndikuukira mdani. Ndi dongosolo lanzeru kwambiri, sichoncho? Komabe, nthawi zina dongosolo lanzeruli limapanga cholakwika chaching'ono. Ndicho chomwe chimachitika m'mikhalidwe yotchedwa matenda a autoimmune . Chomwe chimachitika ndiye kuti ma antibodies athu amayamba kupanga motsutsana ndi zidutswa zinazake za mapuloteni (zotchedwa ma antigen a nyukiliya ochotsedwa , kutanthauza "ma antigen omwe amatha kulekanitsidwa ndi nucleus") omwe amapezeka mu nucleus (pakati pa selo) ya maselo athanzi m'thupi lathu. Zili ngati gulu lathu lankhondo likuukira nzika zathu zathanzi. Pa nthawi yotereyi, mayeso a ENA amathandiza kupeza ma antigen athu omwe ma antibodies amenewa akuukira. Izi zingathandize madokotala kuganiza mtundu wa matenda omwe ali ndi chitetezo chamthupi kapena kutsimikizira kuti mulibe matenda otere.

Kodi ndiyenera kuchita mayeso a ENA liti?

Si aliyense amene adzafunika kuyesedwa kwa ENA. Pali zochitika zingapo zomwe dokotala angalamule mayesowa:

• Ngati muli ndi zizindikiro za matenda a autoimmune (monga kupweteka kwa mafupa , kutopa kwambiri, mavuto a khungu) ndipo mwakhala mukuyesedwa bwino za Antinuclear Antibody (ANA) , mayeso a ANA ndi mayeso a matenda a autoimmune .Kuyesa koyambira koti mudziwe. Ngati kuli ndi kachilombo ka HIV, mayeso a ENA athandiza kufufuza zomwe zidzachitike pambuyo pake.
• Ngati muli ndi pakati ndipo munapezekapo kale ndi lupus . Panthawiyi, ma antibodies anu amatha kudutsa mu placenta kupita kwa mwana wanu ndikuyambitsa vuto lotchedwa neonatal lupus . Izi zingayambitse mavuto mwa mwana, monga kutsekeka kwa mtima , kotero dokotala wanu angakulangizeni kuti muyesedwe mayeso a ENA kuti muwone izi.

Ndi mitundu yanji ya matenda yomwe mayeso a ENA amayesa kuzindikira?

Pali mitundu ingapo ya ma antibodies omwe mayeso a ENA amafufuza. Ma antibodies amenewa amagwirizanitsidwa makamaka ndi matenda aliwonse a autoimmune. Matenda ofala kwambiri omwe mayesowa amafufuza ndi awa:

• Lupus (Systemic Lupus Erythematosus /SLE)
• Matenda a Sjögren
• Matenda a Mixed Connective Tissue (MCTD)
• Scleroderma/systemic sclerosis
• Polymyositis
• Dermatomyositis

Matenda aliwonsewa amakhala ndi zizindikiro zosiyana, kotero dokotala adzayerekeza zizindikiro zanu ndi zotsatira za mayeso a ENA kuti apeze yankho.

Kodi mayeso a ENA amachitidwa bwanji? Kodi amagwira ntchito bwanji?

Ndi zophweka kwambiri. Katswiri wa labu amatenga chitsanzo cha magazi pang'ono kuchokera mumtsempha womwe uli m'dzanja lanu. Kenako amagwiritsa ntchito chitsanzo cha magazi ichi poyesa ENA. Mu labu, amagwiritsa ntchito zizindikiro zapadera. Zizindikirozi zimamatira ku ma antibodies omwe akufunafuna ngati alipo. Kenako zizindikirozi " zimawala" kapena kusintha mtundu. Umu ndi momwe akatswiri a zamankhwala amatha kuwona ngati ma antibodies awa alipo kapena ayi. Ukadaulo wapamwamba kwambiri, sichoncho?

Kodi mayeso a ENA amafufuza mitundu yanji ya ma antibodies?

Kawirikawiri, mayeso a ENA amafufuza ma antibodies omwe amayankha ma antigen anayi kapena asanu ndi limodzi omwe amapezeka mkati mwa maselo athu. Ma antibodies onsewa amagwirizanitsidwa ndi matenda enaake a autoimmune ndi matenda ena. Mwachitsanzo, ma antibodies ena amagwirizanitsidwa ndi lupus.Zina zimakhala ndi matenda enieni, pomwe zina zimagwirizana kwambiri ndi matenda a Sjögren . Ichi ndichifukwa chake mayesowa ndi ofunikira pozindikira matendawa. Dokotala wanu adzasankha ma antibodies oti muwayang'anire kutengera zizindikiro zanu.

Kodi ndiyenera kukonzekera pasadakhale mayeso a ENA?

Iyi ndi nkhani yabwino kwambiri! Simukuyenera kukonzekera mwapadera musanapite kukayezetsa ENA. Mutha kudya ndi kumwa bwino komanso kumwa mankhwala anu. Ndi bwino kulankhula ndi dokotala wanu za izi kuti mutsimikize.

Kodi mungayembekezere chiyani mukamachita mayeso a ENA?

Monga tanenera kale, dokotala, namwino, kapena katswiri wa labu adzagwiritsa ntchito singano yaying'ono kutenga magazi ochepa kuchokera mumtsempha womwe uli m'dzanja lanu. Mungamve kupweteka kapena kusasangalala singano ikalowetsedwa ndikuchotsedwa. Izi zimatenga masekondi ochepa okha. Ngati mukuopa singano, zingathandize kuyang'ana kwina panthawiyi. Kenako chitsanzo cha magazi chidzatumizidwa ku labotale kuti akayesedwe.

Kodi zoopsa za mayeso a ENA ndi ziti?

Zoopsa za mayeso a ENA ndizochepa kwambiri , koma zinthu zazing'ono zimatha kuchitika magazi akatengedwa.

• Nthawi zina, ngati n'kovuta kupeza mtsempha, mungafunike kuboola singano kangapo. Zimenezo zimakhala zovuta pang'ono.
• Mungamve chizungulire pang'ono kapena kukomoka mukatengedwa magazi.
• Pakhoza kukhala chotupa chachikulu kapena kusonkhanitsa magazi pansi pa khungu pomwe singano inalowetsedwa (izi zimatchedwa hematoma ).
• Kawirikawiri, matenda amatha kuchitika pamalo pomwe palumidwa.
• Anthu ena amatha kutuluka magazi ambiri kwa kanthawi magazi atatengedwa.

Ngati chinthu chonga ichi chichitika, musachite mantha, ingodziwitsani ogwira ntchito zachipatala.

Kodi mumapeza bwanji zotsatira za mayeso a ENA? Kodi zikutanthauza chiyani?

Zotsatira za mayeso nthawi zambiri zimakhala zoipa , zabwino , kapena malire (omwe amatchedwanso kuti osatsimikizika) . Magawo abwinobwino amatha kusiyana pang'ono kutengera labotale yomwe imachita mayesowo. Chifukwa chake, lipoti lanu la mayeso liyenera kuphatikiza zotsatira zanu pamodzi ndi mndandanda wazomwe zikuwonetsedwa mu labotale.

• Zotsatira zabwino zimatanthauza kuti antibody yoyenera yapezeka mu chitsanzo cha magazi anu.
• Zotsatira zoyipa zikutanthauza kuti panalibe ma antibodies olimbana ndi antigen yoyenera m'magazi anu, kapena panali ochepa kwambiri.

Ngati mayeso a ENA ali ndi kachilombo, kodi zikutanthauza kuti ndili ndi lupus?

Ayi, simunganene kuti muli ndi matenda enaake monga lupus chifukwa cha zotsatira za mayeso amodzi okha.

Izi ndizofunikira kwambiri. Kuyezetsa kwa ENA sikutanthauza kuti muli ndi lupus . Mwachitsanzo, anthu ambiri omwe ali ndi matenda a Sjögren's syndrome amapezeka kuti ali ndi ma antibodies otchedwa anti-SSA ndi anti-SSB . Komabe, ma antibodies omwewa amathanso kukhala ndi kachilombo mwa munthu amene ali ndi lupus kapena matenda ena. Chifukwa chake, dokotala wanu adzatenga zotsatira za mayeso a ENA, zizindikiro zanu, ndi zotsatira zina za mayeso (monga mayeso a ANA, CRP, ESR) pamodzi kuti adziwe matenda .

Ndiyenera kukaonananso ndi dokotala liti?

Ngati muli ndi mafunso kapena nkhawa zokhudzana ndi zotsatira za mayeso anu, onetsetsani kuti mwalankhula ndi dokotala wanu. Komanso, ngati muli ndi ululu, kutupa, mafinya pamalo omwe magazi amatengedwa, kapena zizindikiro za matenda monga malungo, pitani kuchipatala mwamsanga (ETU) .

Kodi kusiyana pakati pa mayeso a ANA ndi mayeso a ENA ndi kotani?

Izi ndi vuto kwa anthu ambiri. Tiyeni tiwone kusiyana pakati pa awiriwa. Ganizirani za mayeso a ANA ngati mayeso oyamba komanso ofala kwambiri omwe apolisi amachita. "Kodi pali vuto apa, kodi pali vuto la autoimmune?" Kawirikawiri amawunikidwa. Izi zimayesa ngati pali ma antibodies angati a antinuclear (ma antibodies otsutsana ndi nucleus ya selo) m'magazi mwanu. Mayeso a ENA ali ngati mayeso apadera omwe amachitidwa pambuyo pake. Ngati ANA ili ndi positive, amafufuza mozama ndikufunsa kuti, "Chabwino, ngati pali vuto, ndi chiyani kwenikweni? Ndi mapuloteni ati enieni (antigen) m'thupi lathu omwe ma antibodies awa amapangidwa motsutsana nawo?" Ndiko kuti, mayeso a ENA ndi enieni kuposa mayeso a ANA. Anthu ambiri omwe ali ndi matenda a autoimmune ali ndi mayeso abwino a ANA. Komabe, anthu athanzi omwe alibe matenda a autoimmune nthawi zina amatha kukhala ndi mayeso abwino a ANA (mayeso a ENA nthawi zambiri amakhala opanda ma antibodies mwa anthu otere). Ndicho chifukwa chake madokotala amalamula mayeso a ENA kuti adziwe zambiri zokhudza matenda a autoimmune mwa munthu yemwe ali ndi mayeso abwino a ANA.

Pomaliza, zinthu zoti muzikumbukira

Gulu la ENA (Extractable Nuclear Antigen panel) ndi mayeso ofunikira omwe amapatsa dokotala wanu zambiri zokhudza ma antibodies omwe akuwononga maselo anu ndipo angayambitse zizindikiro zanu.

Palibe mayeso amodzi omwe angapeze matenda a autoimmune.

Dokotala wanu adzatenga zotsatira za ENA, zizindikiro zanu, ndi mayeso ena pamodzi kuti adziwe matenda molondola. Chifukwa chake, ngati muli ndi mafunso okhudza zotsatira za mayeso anu kapena momwe angakhudzire zisankho zanu zaumoyo, musaope kufunsa dokotala wanu. Kenako inunso mutha kumvetsetsa bwino. Mayeso a ENA, matenda odziteteza ku matenda, ma antibodies, ma antigen, lupus, mayeso a magazi, mayeso a ANA