Kodi munayamba mwadzifunsapo kuti ubongo wathu ndi wotanganidwa bwanji? Zili ngati Colombo Town, ndi zinthu zambirimbiri zikuchitika nthawi imodzi. Mauthenga akupita mobwerezabwereza, zisankho zikupangidwa, malingaliro akulamulidwa... zonsezi zimachitika kudzera mu netiweki ya amithenga ang'onoang'ono a mankhwala. Ndiye, chimachitika ndi chiyani pamene chilichonse chikuyenda mozungulira pamalo otanganidwa chonchi? Chilichonse chimakhala chisokonezo, sichoncho? Pali winawake mu ubongo wathu amene amaletsa chisokonezo chimenecho, amatonthoza chilichonse, ndikuchilamulira. Lero tikambirana za mthenga wofunika uja, kutanthauza 'kutseka' kwachilengedwe mu ubongo wathu. Ameneyo ndi GABA.
Kodi GABA ndi chiyani kwenikweni?
Mwachidule, GABA , yomwe ndi chidule cha gamma-aminobutyric acid, ndi mthenga wa mankhwala muubongo mwathu. Mu zamankhwala, timatcha ma neurotransmitters awa. Monga postmen, amanyamula mauthenga kuchokera ku selo imodzi ya mitsempha muubongo kupita ku ina.
Koma uthenga umene GABA ili nawo ndi wapadera pang'ono. Si uthenga woti "Fulumirani, thawani." Ndi uthenga woti "Chabwino, chabwino, tsopano. Chepetsani pang'ono, bata." Izi zikutanthauza kuti GABA imawongolera pang'ono ntchito ya dongosolo lathu la mitsempha - kutanthauza ubongo ndi msana. Imaletsa maselo a mitsempha kuti asayambe kugwira ntchito mopanda chifukwa.
Ichi ndichifukwa chake timakhulupirira kuti GABA imagwira ntchito yofunika kwambiri pakutonthoza maganizo athu ndikulamulira zinthu monga kupsinjika maganizo, mantha, ndi nkhawa. Ili ngati mankhwala otonthoza ubongo wathu.
Tiyeni tiwone bwino momwe GABA imagwirira ntchito.
Kuti mumvetse izi, tangoganizani kuti maselo amitsempha muubongo wanu akulankhulana. Koma sali olumikizana. Pali mpata wochepa pakati pa selo limodzi ndi lina. Timatcha kuti synapse. Uthenga ukafunika kutumizidwa, neurotransmitter imatulutsidwa kuchokera ku selo limodzi, imasambira kudutsa mpata umenewo, ndikulumikizana ndi cholandirira chapadera pa selo lotsatira.
Zili ngati kiyi ndi loko. Si kiyi iliyonse yomwe ingatsegule loko iliyonse. Komanso, si `Neurotransmitter` iliyonse yomwe ingalumikizane ndi `Receptor` iliyonse. `Kiyi` yotchedwa GABA imatha kutsegula `maloko` otchedwa GABA receptors okha.
Pamene GABA ikupita ndi kumangirira ku 'receptor' yake, uthenga womwe selo lotsatira la mitsempha limalandira ndi "kuchepetsa zochita zanu." Izi zikutanthauza kuti, kuthekera kwa selo limenelo kulandira mauthenga kuchokera ku maselo ena, kupanga mauthenga atsopano, kapena kutumiza mauthenga ku maselo ena kumachepa. Mwanjira imeneyi, ntchito yonse ya ubongo imachepa. Monga momwe nyali ya magalimoto imakhalira yofiira pamsewu wotanganidwa, magalimoto amaima ndipo magalimoto amawongoleredwa pang'ono.
GABA ndi Glutamate - ma switch awiri a 'On' ndi 'Off' muubongo
Kuti ubongo wathu ugwire ntchito bwino, kulinganiza bwino n'kofunika kwambiri. Tikamalankhula za GABA, timafunikanso kulankhula za Glutamate , yomwe ndi yosiyana ndi ubongo wathu.
GABA ndi glutamate zimagwira ntchito ngati ma switch awiri a 'On' ndi 'Off'.
- GABA ndiye chosinthira chachikulu cha ubongo chomwe chimaletsa kugwira ntchito ndikukutonthozani.
- Glutamate ndiye chinthu chachikulu chomwe ubongo umagwiritsa ntchito poyambitsa ubongo . Izi zikutanthauza kuti, ndi 'neurotransmitter' yomwe imalimbikitsa maselo amitsempha ndikuwonjezera ntchito zawo.
Taganizirani izi ngati accelerator ndi brake m'galimoto. Ngati mukufuna kuyendetsa galimoto bwino, muyenera kugwiritsa ntchito zonse ziwiri moyenera komanso panthawi yoyenera. Kukhala ndi imodzi yokha sikungathandize. Ngati muli ndi accelerator yokha, mudzagwa kulikonse. Ngati muli ndi brake yokha, simungathe kupita patsogolo. Mofananamo, kuti ubongo wathu ugwire ntchito bwino komanso moyenera, payenera kukhala mgwirizano wosavuta pakati pa zotsatira za GABA zotonthoza ndi zotsatira zolimbikitsa za glutamate.
Chodabwitsa n'chakuti, chinthu chotonthoza ichi chotchedwa GABA chimapangidwa kuchokera ku chinthu chomwecho cholimbikitsa, glutamate. Glutamate imasandulika GABA pogwiritsa ntchito enzyme yapadera.
Kodi chimachitika ndi chiyani ngati milingo ya GABA siili bwino?
Ngati kulinganiza komwe takambiranaku kwatayika, makamaka ngati ntchito ya GABA yachepa, 'mabuleki' a ubongo sagwira ntchito bwino. Kenako ntchito ya ubongo idzawonjezeka mosafunikira, ndipo mavuto angapo angabuke. Tiyeni tiwone zina mwa matenda omwe akuganiziridwa kuti akugwirizana ndi kuchepa kwa ntchito ya GABA pansipa.
| Matenda | Kufotokozera kosavuta |
|---|---|
| Nkhawa ndi Matenda a Maganizo | Pamene palibe GABA yokwanira yotonthoza maganizo, mantha osafunikira, malingaliro osokoneza, ndi kusakhazikika maganizo kungachitike. |
| Schizophrenia | Matenda amisala ovuta omwe amakhudza malingaliro, malingaliro, ndi khalidwe. Pali umboni wina wosonyeza kuti kusalinganika kwa GABA kungayambitse izi. |
| Matenda a Autism Spectrum | Vuto la chitukuko lomwe limakhudza maubwenzi ndi kulankhulana. Lingaonekere mu kusintha kwa dongosolo la GABA. |
| Kuvutika maganizo | Chisoni cha nthawi yayitali komanso kutaya chidwi ndi zinthu. Izi zitha kukhala zokhudzana ndi kuchepa kwa GABA. |
| Khunyu / Kugwidwa | Kuwonjezeka kwadzidzidzi komanso kosalamulirika kwa ntchito zamagetsi muubongo. Chifukwa chachikulu cha izi ndi kufooka kwa njira ya 'brake' ya GABA. |
| Matenda a Huntington | Matenda obadwa nawo omwe amawononga maselo a ubongo pang'onopang'ono. |
| Kusazindikira bwino | Kugona kwambiri masana kapena kugona kwa nthawi yayitali kungayambitsidwe ndi kugwira ntchito mopitirira muyeso kwa dongosolo la GABA. |
Kodi pali mankhwala aliwonse omwe amalimbikitsa GABA?
Inde. Popeza GABA imagwira ntchito yofunika kwambiri muubongo wathu, opanga mankhwala apanga mankhwala angapo omwe amalimbana ndi dongosolo la GABA. Mankhwalawa amagwira ntchito powonjezera mphamvu zachilengedwe za GABA zotonthoza kapena kuchita zinthu ngati GABA.
Chofunika: Mankhwala otsatirawa ndi zitsanzo chabe. Musagwiritse ntchito kapena kusiya kuwagwiritsa ntchito pazifukwa zilizonse popanda upangiri ndi malangizo a dokotala. Ena mwa mankhwalawa akhoza kukhala osokoneza bongo ndipo angayambitse zotsatirapo zoyipa.
| Gulu la mankhwala / dzina | Kodi imagwiritsidwa ntchito pa chiyani? (Mwachitsanzo) |
|---|---|
| Benzodiazepines - mwachitsanzo Diazepam (Valium®), Alprazolam (Xanax®) | Kuchepetsa nkhawa, kuwongolera khunyu, kuwongolera zizindikiro za kusiya kumwa mowa, komanso kumasula minofu. |
| Ma Barbiturates | Izi ndi mtundu wa mankhwala ochepetsa ululu. Amagwiritsidwa ntchito pochiza khunyu ndi mankhwala oletsa ululu. |
| Valproic Acid | Amaperekedwa kuti achepetse khunyu komanso ngati chothandizira kukhazikika kwa malingaliro. |
| Zolpidem (Zolpidem - Ambien®) | Piritsi logonetsa lomwe limagwiritsidwa ntchito pochiza kusowa tulo. |
| Propofol | Mankhwala amphamvu omwe amagwiritsidwa ntchito pochiza ululu panthawi ya opaleshoni. |
| Baclofen | Mankhwala operekedwa kuti achepetse kuuma kwa minofu kosafunikira (kupindika). |
Zoona kapena zabodza zokhudza zakudya ndi zowonjezera za GABA
Mwina mwawonapo "GABA Supplements" ikugulitsidwa m'masitolo ogulitsa mankhwala kapena pa intaneti. Amati angakuthandizeni kupumula, kugona, komanso kuchepetsa nkhawa. Koma pali vuto.
Ubongo wathu ndi malo otetezeka kwambiri. Sulola chilichonse kulowa. Pali njira yapadera yotetezera ubongo yotchedwa Blood-Brain Barrier . Ili ngati ngalande yozungulira nyumba yachifumu. Zinthu zofunika kwambiri ku ubongo zokha ndi zomwe zimaloledwa kudutsa mu njira yotetezerayi.
Ofufuza ambiri amakhulupirira kuti mphamvu ya GABA supplements yomwe timamwa kunja kuti tidutse chotchinga cha magazi ndi ubongo ndi yotsika kwambiri. Chifukwa chake, momwe zimakhudzira ubongo sizikudziwikabe. Anthu ena amati amakhala bata akamamwa supplements izi. Palibe mgwirizano wasayansi pankhani ya ngati izi ndi GABA yomwe ikufika mu ubongo, kapena ngati ndi placebo effect.
Choncho, onetsetsani kuti mwalankhula ndi dokotala wanu musanamwe mankhwala owonjezera a GABA. Iye ndiye munthu woyenera kusankha ngati ndi oyenera matenda anu kapena ayi.
Kodi pali GABA mu zakudya?
Inde, GABA imapezeka mwachibadwa muzakudya zina, makamaka zakudya zowiritsa.
- Kimchi
- Miso
- Tempeh
Kuphatikiza apo, tiyi wobiriwira, wakuda, ndi oolong ulinso ndi GABA. Komanso, pali chikhulupiriro chakuti zakudya monga mpunga wofiirira, soya, broccoli, sipinachi, tomato, ndi kolifulawa zimathandiza kuwonjezera kupanga kwa GABA m'thupi lathu.
Koma monga momwe zilili ndi zakudya zowonjezera, palibe umboni wokwanira wosonyeza kuchuluka kwa GABA kuchokera muzakudya izi komwe kumafika ku ubongo. Koma kudya zakudya zoyenera komanso zopatsa thanzi ndikwabwino kwa thupi m'njira zonse.
Uthenga Wopita Nawo Kunyumba
- GABA ndiye mthenga wamkulu wa mankhwala 'otonthoza' muubongo mwathu. Imagwira ntchito ngati 'brake' muubongo mwathu.
- Kugwirizana pakati pa glutamate, yomwe imawonjezera ntchito ya ubongo, ndi GABA, yomwe imachepetsa ntchito, ndikofunikira kuti munthu akhale ndi thanzi labwino.
- Kuchepa kwa GABA kungagwirizane ndi matenda osiyanasiyana, monga nkhawa, kuvutika maganizo, ndi khunyu.
- Mankhwala ambiri ofunikira omwe amagwiritsidwa ntchito mu mankhwala amalimbana ndi njira ya GABA. Mankhwalawa ayenera kugwiritsidwa ntchito pokhapokha ngati dokotala akuwayang'anira.
- Palibe umboni wokwanira wa sayansi wokhudza momwe ma supplementary a GABA amagwirira ntchito pamsika, ndipo n'zokayikitsa ngati amalowadi muubongo.
- Ngati muli ndi vuto la nkhawa, kupsinjika maganizo, kapena kusowa tulo, ndikofunikira kwambiri kufunsa dokotala wodziwa bwino ntchito ndikupempha upangiri , m'malo mongodalira zakudya zowonjezera kapena zowonjezera.
💬 Comments (0)
Palibe ndemanga zomwe zatumizidwa pano. Onjezani ndemanga yanu pano koyamba.
Onjezani ndemanga yanu