Zotupa zachilendo zomwe zimakula m'thupi komanso chiopsezo cha khansa - Tiyeni tiphunzire za Gardner Syndrome

Kodi mukupeza ziphuphu zachilendo m'malo osiyanasiyana pathupi lanu? Mwina muli ndi mano ambiri kuposa omwe muyenera kukhala nawo mukamayamwa mano? Ngakhale izi zingawoneke ngati zinthu wamba, nthawi zina pangakhale nkhani yaikulu kumbuyo kwake. Lero tikulankhula za matenda osowa kwambiri, koma ofunika kwambiri omwe aliyense ayenera kudziwa. Umenewo ndi Gardner Syndrome.

Kodi Gardner Syndrome ndi chiyani, mwachidule?

Mwachidule, uwu ndi matenda osowa omwe tingapeze kuchokera kwa makolo athu kudzera m'majini. Ndi matenda obadwa nawo. Munthu amene ali ndi matendawa amayamba kudwala matenda otupa m'mbali zosiyanasiyana za thupi lake.

Chomwe chimachitika n'chakuti machubu ang'onoang'ono mazana ambiri amakula mkati mwa matumbo. Machubu amenewa amatchedwa ma polyps . Choopsa kwambiri ndichakuti ngati sanalandire chithandizo, ma polyps onsewa ali pachiwopsezo chachikulu chodzakhala khansa ya m'matumbo .

Kuwonjezera pa m'matumbo, zotupa zomwe si khansa zimathanso kufalikira m'mafupa, m'matumbo, pakhungu, ndi m'minyewa ina yofewa. Anthu omwe ali ndi matendawa ali pachiwopsezo chotenga mitundu ina yambiri ya khansa.

Kodi vutoli ndi lofala bwanji? Ndani amalipeza?

Izi ndi matenda osowa kwambiri. Mwachitsanzo, m'dziko ngati America, munthu m'modzi yekha pa anthu miliyoni imodzi ndi amene amapezeka ndi matendawa.

Popeza ndi matenda obadwa nawo, anthu ambiri omwe ali ndi matenda a Gardner ali ndi mwayi waukulu wokhala ndi amayi kapena abambo omwe ali ndi matendawa. Izi zikutanthauza kuti amapatsiridwa kudzera m'majini kuchokera ku mibadwomibadwo.

Kodi zizindikiro za izi ndi ziti?

Zizindikiro za matenda a Gardner zimasintha pakapita nthawi. Zizindikiro zina zimatha kuonekera ali mwana.

Ndi matenda ena ati omwe amabwera chifukwa cha matenda a Gardner?

Munthu amene ali ndi matenda a Gardner ali pachiwopsezo chachikulu chotenga matenda otsatirawa:

• Mano owonjezera
• Mafupa a mafupa (osteomas)
• Zotupa za Desmoid - Ngakhale izi si khansa, zimatha kukula mofulumira ndikuwononga minofu yozungulira.
• Matenda a mafuta (Lipomas)
• Ma Fibroma
• Adenomas - Zotupa zomwe sizili khansa zomwe zimapangidwa m'matenda a gland.
• Ma cysts a epithelial
• Matenda omwe amakhudza retina ya diso (CHRPE - congenital hypertrophy of retinal pigment epithelium)
• Khansa ya m'mimba
• Khansa ya chiwindi
• Khansa ya m'matumbo

Chifukwa chiyani izi zikuchitika? Chifukwa chake ndi chiyani?

Chifukwa cha izi ndi vuto lomwe lili mu majini athu. Kunena zoona, pali jini yotchedwa APC gene . Ntchito yake yayikulu ndikulamulira maselo m'thupi lathu kuti asagawane ndikuchulukana mwachangu kwambiri. Monga momwe mabuleki amagwirira ntchito pagalimoto. Majini ngati awa amatchedwa majini oletsa kutupa , zomwe zikutanthauza kuti amaletsa kutupa kuti kusapangidwe.

Munthu amene ali ndi matenda a Gardner syndrome ali ndi jini ya APC yolakwika. Izi zikutanthauza kuti brake yomwe imalamulira kugawikana kwa maselo sigwira ntchito. Zotsatira zake, maselo amagawikana mosalamulirika ndikuyamba kupanga zotupa ndi ma polyps.

Kodi dokotala amazindikira bwanji matendawa?

Popeza matendawa ali ndi zizindikiro zosiyanasiyana, dokotala amagwiritsa ntchito mayeso angapo kuti awazindikire.

• Kuyesa majini: Kuyesa kumeneku kumachitika kuti muwone ngati muli ndi vuto mu jini yanu ya APC. Dokotala wanu angakulimbikitseni izi, makamaka ngati wina m'banja mwanu ali ndi matendawa.
• Mayeso a kamera: Izi zimaphatikizapo kulowetsa kamera kakang'ono m'thupi kuti kaone mkati mwa matumbo.
• Sigmoidoscopy
• Endoscopy
• Colonoscopy - Ichi ndi chomwe chimazindikira bwino ma polyps m'matumbo.

Kodi mankhwala ochizira izi ndi otani?

Chithandizo chimadalira zizindikiro zanu.

Tangoganizani kuti muli ndi mano owonjezera. Chimenecho chingakhale chizindikiro choyamba cha matendawa. Kenako muyenera kufunsa dokotala wa mano kuti akuchotseni manowo ndikukonza mano ena onse. Ngati muli ndi zotupa za desmoid, mutha kulandira chithandizo monga chemotherapy kuti zichepetse manowo.

Komabe, vuto lalikulu komanso loopsa kwambiri ndi matendawa ndi ma polyps omwe amapangika m'matumbo. Opaleshoni imafunika kuti izi zisanduke khansa.

Kodi matendawa angachiritsidwe kwathunthu?

Mwatsoka, Gardner syndrome singathe kuchiritsidwa kwathunthu.

Komabe, izi zitha kuthandizidwa bwino. Ndi chithandizo choyenera komanso kuyezetsa nthawi zonse, matenda akuluakulu monga khansa amatha kuzindikirika ndikuchiritsidwa msanga. Choncho palibe chifukwa chochita mantha.

Kodi n'zotheka kukhala ndi moyo wabwinobwino ndi matendawa?

Inde, mungathe. Komabe, pakhoza kukhala kusintha kwina pa moyo wanu mutachita opaleshoni. Mwachitsanzo, kuchotsedwa kwa m'matumbo anu kudzasintha momwe mumagayira chakudya ndi kutulutsa ndowe. Mungafunikenso kukhala ndi njira ina yolowera ndi thumba la ostomy lomwe limayikidwa pamimba panu kuti ndowe idutse. Dokotala wanu adzakufotokozerani izi mwatsatanetsatane.

Opaleshoni yoletsa khansa ya m'matumbo kuti isakule chifukwa cha matendawa ingakulitse moyo wa munthu. Kafukufuku wina anasonyeza kuti 100% ya anthu omwe anachitidwa opaleshoni ya proctocolectomy anali ndi moyo patatha zaka 5.

Kodi mumadzisamalira bwanji?

Kukhala ndi Gardner syndrome kumatanthauza kukhala ndi chiopsezo chotenga khansa uli mwana. Sikophweka. Kuthana ndi kusatsimikizika kumeneko kungakhale kovuta m'maganizo.

Choncho, ndikofunikira kuyezetsa khansa panthawi yoyenera. Izi zikutanthauza kuti ngati khansa yayamba, imatha kupezeka ndi kuchiritsidwa msanga.

Ngati mukumva kupsinjika maganizo ndi izi, lankhulani ndi dokotala wanu za izi. Ngati kuli kofunikira, funani upangiri.

Ndiyenera kupita kwa dokotala liti?

Ngati muwona kusintha kulikonse kwatsopano m'thupi lanu, mwachitsanzo, chotupa chatsopano, kapena kusintha kwa matumbo anu, makamaka ngati muwona magazi mu ndowe zanu , pitani kwa dokotala nthawi yomweyo.

Ndi mafunso ati omwe muyenera kufunsa dokotala wanu?

Mukapita kwa dokotala wanu, musaiwale kufunsa mafunso awa.

• Kodi ndi mankhwala ati omwe akugwiritsidwa ntchito panopa pochiza zizindikiro zanga?
• Kodi ndikufunika opaleshoni?
• Ndi mayeso otani omwe ndiyenera kuchita ndipo ndiyenera kuwachita kangati?
• Ndi kusintha kotani m'thupi langa komwe ndiyenera kusamala nako kwambiri?
• Kodi ndi bwino kuti banja langa lonse lipite kukayezetsa majini?

Matenda a Gardner si chinthu choopa, koma ndi vuto lomwe liyenera kuyang'aniridwa mosamala komanso moyenerera. Ndi upangiri woyenera wachipatala komanso kuyezetsa, mutha kukhala ndi moyo wathanzi komanso wautali.