Kodi nthawi zambiri mumamva kutentha pamtima kapena kupweteka pachifuwa? Kodi mukuganiza kuti muli ndi zomwe tonse timatcha "gastritis"? Ngati mukumva kuti chakudya sichigayidwa ndipo nthawi zonse mumakhala ndi ululu m'mimba, chimodzi mwa zifukwa zake chingakhale mankhwala omwe amapangidwa m'thupi lathu. Lero tikambirana za mahomoni otchedwa Gastrin, omwe mwina simunamvepo, koma omwe ndi ofunikira kwambiri pa kugaya chakudya.
Mwachidule, kodi Gastrin ndi chiyani?
Gastrin ndi mahomoni omwe amathandiza kuti kugaya chakudya chanu kugwire bwino ntchito. Tsopano mwina mukudabwa kuti mahomoni awa ndi chiyani. Taganizirani ngati mthenga wamng'ono mkati mwa thupi lathu. Mahomoni awa amayenda m'magazi m'thupi lonse, akuuza chiwalo chilichonse kuti, "Chabwino, tsopano chitani ntchito iyi" ndi "Tsopano siyani kugwira ntchito iyi." Choncho gastrin ndi mthenga wofunikira kwambiri amene amapereka malangizo ku matumbo athu.
Homoni ya gastrin iyi imapangidwa makamaka ndi mtundu wapadera wa selo lotchedwa G-cells m'makoma a gawo la pansi la mimba yathu (m'mimba) . Kuphatikiza apo, pang'ono zimapangidwa ndi gawo loyamba la matumbo athu ang'onoang'ono (duodenum) ndi kapamba.
Kodi zinthu zazikulu zomwe gastrin amachita m'thupi lathu ndi ziti?
Gastrin imagwira ntchito zingapo zofunika kwambiri m'thupi lathu. Tiyeni tiwone zomwe zili.
- Kupanga asidi m'mimba: Kuti chakudya chomwe timadya chigayidwe bwino, m'mimba mwathu mumafunika mtundu wina wa asidi. Izi zimatchedwa hydrochloric acid. Gastrin ndi yomwe imapatsa m'mimba chizindikiro chakuti, "Chabwino, yambani kupanga asidi tsopano." Asidi uyu amayamba kuswa mapuloteni omwe ali mu chakudya.
- Zimayambitsa minofu ya m'mimba kufinya: Chakudya chikalowa m'mimba, chimayenera kusakanikirana bwino, kusakaniza ndi asidi, ndikusweka. Izi zimafuna kuti minofu yomwe ili m'makoma a m'mimba isunthe mmbuyo ndi mtsogolo ndikufinya. Izi zimatchedwa kuyenda kwa m'mimba. Gastrin ndi yomwe imauza minofu iyi kuti igwire ntchito.
- Zimathandiza kuteteza khoma la m'mimba: Asidi m'mimba ndi wamphamvu kwambiri. Choncho kuti makoma a m'mimba asawonongeke ndi asidi wamphamvuyo, maselo omwe ali pakhoma ayenera kukonzedwanso nthawi zonse. Ichi ndi chomwe timachitcha kuti mucosa ya m'mimba. Gastrin imathandizanso maselowa kukulitsa atsopano.
- Imathandiza kapamba ndi ndulu: Pamodzi ndi mahomoni ena, cholecystokinin, gastrin imatumiza zizindikiro ku kapamba ndi ndulu zathu kuti zitulutse madzi awo ogaya chakudya.
Ubongo ndi matumbo athu nthawi zonse zimalankhula. Ingoganizirani, mukaganizira za chakudya chokoma, kapena ngakhale kununkhiza, mumataya malovu, sichoncho? Mofananamo, ubongo umatumizanso uthenga m'mimba, kuti, "Chakudya chakonzeka, yambani kupanga gastrin."
Kodi chimachitika ndi chiyani ngati gastrin ikukwera?
Amati kuchuluka kwa chinthu chilichonse sikwabwino. Zimenezi zimachitikanso ndi gastrin. Pamene kuchuluka kwa gastrin m'magazi kukukwera kwambiri kuposa momwe kungafunikire, timatcha hypergastrinemia . Nanga bwanji ngati izi zitachitika?
Mwachidule, gastrin ikachuluka, kupanga asidi m'mimba kumawonjezekanso. Zili ngati kukweza kutentha pa chitofu kwambiri. Asidi wochulukirapoyu amayamba kuwononga mkati mwa mimba. Izi zili choncho chifukwa:
- Matenda a Zilonda Zam'mimba: Asidi woopsa uyu amatha kutentha makoma a m'mimba kapena matumbo ang'onoang'ono, zomwe zimayambitsa zilonda.
- Matenda a gastroesophageal reflux (GERD) amapezeka pamene asidi wochuluka m'mimba amatha kubwerera m'mimba, zomwe zimayambitsa zizindikiro monga kutentha pamtima ndi kupweteka pakhosi.
Ngati muli ndi kutentha pamtima pafupipafupi, ndipo sikutha ngakhale mutamwa mankhwala, dokotala wanu angakuwuzeni kuti muyeze magazi kuti muwone kuchuluka kwa gastrin m'thupi lanu.
Kodi ndi matenda ati omwe amayambitsa kuchuluka kwa gastrin m'magazi?
Pakhoza kukhala zifukwa zosiyanasiyana zomwe zimapangitsa kuti gastrin ikule. Nthawi zina imatha kuwonjezeka ndi acidity m'mimba, ndipo nthawi zina gastrin imatha kuwonjezeka ngakhale acidity ili yochepa. Kuti mumvetse izi, onani tebulo ili m'munsimu.
| Udindo | Kufotokozera kosavuta |
|---|---|
| Ngati gastrin ndi asidi m'mimba zimakwera, ndiye kuti pali kuwonjezeka kwa shuga m'magazi. | |
| Matenda a Gastrinoma | Izi ndi zotupa zomwe zimapanga gastrin zomwe zimakula mu kapamba kapena m'matumbo ang'onoang'ono. Zitha kukhala khansa kapena zosakhala khansa. Matendawa amatchedwa Zollinger-Ellison syndrome . |
| Kulephera kwa impso kosatha | Impso zikalephera kugwira ntchito bwino, njira yochotsera gastrin m'thupi imachepa, zomwe zimapangitsa kuti gastrin m'magazi ikwere. |
| Milandu yomwe gastrin imakwera ndipo asidi m'mimba imachepa | |
| Matenda a gastritis osakhazikika | Pa vutoli, maselo omwe amapanga asidi m'mimba amawonongeka. Pamene kupanga asidi kumachepa, thupi limaganiza kuti likufunika asidi wambiri, motero limapanga gastrin yambiri. Izi zitha kuchitika chifukwa cha matenda a bakiteriya H. pylori kapena mavuto a autoimmune . |
| Mankhwala ochepetsa asidi | Nthawi zambiri timamwa mankhwala a gastritis, monga H2 blockers kapena proton pump inhibitors (PPIs), kuti tilepheretse kupanga asidi m'mimba. Popanda asidi, thupi limayesedwa kuti lipange gastrin yambiri. |
Kodi ndiyenera kuchita chiyani ngati ndili ndi zizindikiro ngati izi?
Ngati nthawi zonse mumakumana ndi chimodzi kapena zingapo mwa zizindikiro zotsatirazi, muyenera kuda nkhawa.
- Kupweteka m'mimba kapena kupweteka kobaya
- Kutentha pamtima pafupipafupi komanso kusadya bwino chakudya
- Chakudya kapena asidi m'mimba akukwera pakhosi
- Kupweteka pakhosi kwa nthawi yayitali komanso kusanza
- Kutsegula m'mimba kosatha (kutsegula m'mimba)
- Mavuto ena a m'mimba
Chofunika kwambiri ndichakuti ngati mwakhala ndi zizindikirozi kwa nthawi yayitali, muyenera kuwona dokotala ndikupempha upangiri, m'malo mongomwa mankhwala kuchokera ku pharmacy.
Dokotala wanu adzalamula kuti muyesedwe magazi kuti muwone kuchuluka kwa gastrin yanu, ngati pakufunika kutero. Angakulangizeninso kuti muyesedwe ndi endoscopy, yomwe imaphatikizapo kugwiritsa ntchito kamera kuti muone m'mimba mwanu. Choyambitsa chikadziwika, chithandizo choyenera chimayamba.
Zidzakhala zosangalatsa kwambiri kudziwa chifukwa chake m'mimba mumakhala ndi mavuto amenewa. Homoni ya gastrin ndi imodzi mwa zovuta. Ndi chithandizo choyenera chamankhwala, mutha kuchotsa mavutowa ndikukhala ndi moyo wabwino.
Uthenga Wopita Nawo Kunyumba
- Gastrin ndi mahomoni ofunikira kwambiri m'mimba mwathu. Amathandiza kupanga asidi m'mimba ndi kugaya chakudya.
- Ngati gastrin imachuluka kwambiri, asidi m'mimba amatha kukwera, zomwe zimapangitsa kuti pakhale matenda monga zilonda zam'mimba ndi matenda a gastroesophageal reflux (GERD).
- Musanyalanyaze zizindikiro monga kupweteka m'mimba pafupipafupi, kupweteka pachifuwa, komanso kusadya bwino chakudya.
- Ngati muli ndi zizindikiro ngati izi, musadzipatse mankhwala, koma onani dokotala woyenerera kuti akupatseni upangiri.
- Miyezo ya gastrin imatha kuyezedwa ndi mayeso osavuta a magazi, kotero palibe chifukwa chodera nkhawa.
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