Kodi mukuvutika ndi kuchepa kwa calcium mutatha opaleshoni? Kungakhale 'Hungry Bone Syndrome'!

Monga mukudziwa, pambuyo pa opaleshoni zina, makamaka zomwe zimachotsa chithokomiro m'khosi kapena ma parathyroid glands omwe ali pafupi, thupi limatha kukhala ndi mitundu yosiyanasiyana ya kusasangalala. Anthu ena angamve kutopa kwambiri, kupweteka thupi, kapena kusokonezeka pang'ono. Chifukwa chake ngati inu kapena munthu amene mumamudziwa akukumana ndi vuto lotere, likhoza kukhala chifukwa cha vuto lomwe tikambirana lero lotchedwa 'Hungry Bone Syndrome'. Dzinali likumveka lachilendo pang'ono, sichoncho? Mwina mukuganiza kuti, "Kodi kukhala ndi mafupa anjala kumatanthauza chiyani?" Tiyeni tiwone mwachidule.

Kodi 'Hungry Bone Syndrome' ndi chiyani?

Mwachidule, Hungry Bone Syndrome ndi vuto lomwe calcium m'magazi mwanu imatsika mwadzidzidzi kwambiri. Madokotala amatcha izi "Hypocalcemia". Vutoli nthawi zambiri limawonekera mutachita opaleshoni ya parathyroid glands. Kodi mukudziwa kuti parathyroid glands ndi yofunika kwambiri polamulira calcium m'thupi lathu?

Anthu omwe ali ndi 'hungry bone syndrome' iyi sangakhale ndi calcium yochepa yokha, komanso nthawi zina amakhala ndi magnesium yochepa (`(Hypomagnesemia)`) ndi phosphorous (`(Hypophosphatemia)`) m'magazi mwawo. Izi ndi mchere wofunikira womwe matupi athu amafunikira.

Koma palibe chodetsa nkhawa nacho. 'Hungry Bone Syndrome' ndi matenda omwe angathe kuchiritsidwa . Chofunika kwambiri ndikuzindikira nthawi yake ndikuyamba kulandira chithandizo.

Kodi vutoli ndi lofala bwanji?

Ofufuza alibe lingaliro lenileni la momwe 'hungry bone syndrome' iyi imafalikira, chifukwa imatha kusiyana malinga ndi munthu.

Komabe, kafukufuku wina wasonyeza kuti anthu pakati pa 4 ndi 13 mwa 100 omwe adachotsedwa opaleshoni ya parathyroid chifukwa cha vuto lotchedwa primary hyperparathyroidism amakhala ndi vutoli. Komanso, malipoti ena amati pambuyo pa opaleshoni ya hyperparathyroidism yachiwiri ndi yachitatu, mwayi woti vutoli lichitike ukhoza kukhala wokwera kufika pa 20 mpaka 70 mwa 100. Chifukwa chake, zikuwoneka kuti izi zitha kukhala zofala nthawi zina.

Kodi zizindikiro za 'Hungry Bone Syndrome' ndi ziti?

Zizindikiro za 'Hungry Bone Syndrome' zimafanana kwambiri ndi zomwe zimachitika chifukwa cha kuchepa kwa calcium m'magazi (Hypocalcemia). Izi zitha kukhala zazing'ono ngati chotupa chaching'ono mwa anthu ena, mpaka zazikulu ngati chisokonezo kapena khunyu mwa ena. Nazi zina mwa zizindikiro:

• Kugubuduza kapena kukoka thupi: Kumva ngati mnofu m'miyendo kapena m'manja ukungogubuduza.
• Kufooka kwa minofu: Kumva wopanda moyo komanso kutopa kwambiri moti sungathe kuchita chilichonse.
• Kupweteka kwa mafupa: Kumva ngati mafupa m'thupi akupweteka.
• Kutopa kwambiri: Kutopa komwe sikutha ngakhale mutagona.
• Kusokonezeka: Kuvutika kuganizira, kusadziwa choti achite.
• Mavuto okumbukira: Kuiwala zinthu.
• Kukwiya kapena kukwiya: Kukwiya pa zinthu zazing'ono, kusakhazikika.
• Kuvutika maganizo: Kumva chisoni komanso kutaya chiyembekezo.
• Kusanza m'milomo, lilime, m'zala, ndi/kapena m'mapazi: Malo awa amamveka ngati osanza, kapena ngati nyerere zikuthamanga.
• Kuvuta kupuma chifukwa cha kupindika kwa minofu ya pakhosi (`(Laryngospasm)`): Izi ndi zoopsa pang'ono, zimapangitsa kuti kupuma kukhale kovuta.
• Kuuma kwa minofu ndi kugwedezeka (`(Tetany)`): Matenda omwe minofu ya thupi imalimba ndi kugwedezeka.
• Kugwidwa ndi khunyu: Ichinso ndi chizindikiro chachikulu.

Pamodzi ndi zizindikirozi, monga tafotokozera kale, magnesium ndi phosphorous zochepa m'magazi (`(Hypomagnesemia)` ndi `(Hypophosphatemia)`) zimathanso kuchitika. Zizindikiro za matendawa zimafanana kwambiri ndi za calcium yochepa. Zingayambitsenso mavuto a minofu, khunyu, komanso kugunda kwa mtima kosakhazikika (`(Arrhythmia)`).

Matenda a njala nthawi zambiri amapezeka mkati mwa maola 18 kuchokera pamene munthu wachita opaleshoni ya parathyroid kapena thyroid .

N’chifukwa chiyani ‘Hungry Bone Syndrome’ imeneyi imachitika?

Pali zifukwa zingapo zazikulu zomwe zimayambitsa 'Hungry Bone Syndrome':

• Pambuyo pa opaleshoni ya parathyroid (`(Parathyroidectomy)`) ya hyperparathyroidism yoyamba kapena yachiwiri.
• Thyrotoxicosis ndi vuto lomwe limachitika pambuyo pa opaleshoni yonse ya chithokomiro.
• Khansa ya prostate ikafalikira ku mafupa (yomwe imafalikira).

Kuti timvetse bwino chifukwa chake izi zimachitika, ndikofunikira kumvetsetsa pang'ono za momwe calcium imayendera m'thupi lathu.

Tangoganizirani, kumbuyo kwa chithokomiro chanu m'khosi mwanu, pali tinthu tina tating'onoting'ono tinayi totchedwa parathyroid glands. Tinthu tating'onoting'onoti timatulutsa hormone yotchedwa parathyroid hormone (PTH) . Ntchito yaikulu ya hormone iyi ya PTH ndikulamulira kuchuluka kwa calcium m'magazi (osati m'mafupa, koma m'magazi). PTH imathandizanso kuwongolera kuchuluka kwa phosphorous (komanso mchere) ndi vitamini D (komanso hormone) m'magazi ndi m'mafupa.

Choncho, thupi lanu likazindikira kuti calcium m'magazi mwanu ndi yotsika, ma glands a parathyroid amatulutsa hormone ya PTH. PTH iyi imatulutsa calcium yochepa m'mafupa ndikuiwonjezera m'magazi. Kenako calcium m'magazi imabwerera mwakale.

Tsopano, taganizirani kuti wina ali ndi ma parathyroid glands omwe amagwira ntchito mopitirira muyeso, ndipo achitidwa opaleshoni kuti awachotse. Chomwe chimachitika ndichakuti kuchuluka kwa mahomoni a PTH omwe kale anali okwera kwambiri kumatsika mwadzidzidzi. Nthawi zina, opaleshoni ya chithokomiro ikachitika, ngati ma parathyroid glands apafupi awonongeka mwangozi, kuchuluka kwa PTH kumathanso kuchepa.

Pamene kuchuluka kwa PTH kwatsika mwadzidzidzi, kuchuluka kwa calcium m'mafupa akale omwe amalowetsedwa m'magazi (`(Resorption)`) kumachepa, ndipo kuchuluka kwa mapangidwe atsopano a mafupa (`(Bone Formation)` kumawonjezeka. Izi zimapangitsa mafupa kukhala "osowa" calcium. Ichi ndichifukwa chake izi zimatchedwa 'hungry bone syndrome'.

Izi ndi zomwe zimachitika khansa ya prostate ikafalikira ku mafupa. Pamenepo, ntchito ya maselo omanga mafupa (`(Osteoblastic activity)` imawonjezeka, kotero mafupa amafunikira calcium yambiri.

Ndani ali pachiwopsezo chachikulu chotenga 'Hungry Bone Syndrome'?

Anthu ena ali ndi mwayi waukulu wopeza vutoli. Tiyeni tiwone omwe ali:

• Kuchuluka kwambiri kwa hormone ya parathyroid (PTH) m'magazi.
• Kuwonjezeka kwa alkaline phosphatase m'magazi.
• Kalisiyumu m'magazi nthawi zambiri imakhala yochepa.
• Kukhala ndi kusowa kwa vitamini D.
• Kuchita opaleshoni ya chithokomiro ndi parathyroid nthawi imodzi.
• Kuchuluka kwa urea nitrogen m'magazi (BUN).
• Kunenepa kwambiri, ndiko kuti, kunenepa kwambiri.
• Kuchotsa opaleshoni ya parathyroid gland yayikulu kuposa yachibadwa.
• Kufalikira kwa maselo a khansa kupita ku mafupa (Metastatic tumors of the bones).
• Kupezeka kwa matenda okhudzana ndi mafupa monga zotupa za bulauni ndi osteitis fibrosa cystica.

Anthu omwe ali ndi zinthu zoopsazi amakhala ndi mwayi waukulu wokhala ndi 'hungry bone syndrome'.

Kodi madokotala amapeza bwanji izi?

Dokotala nthawi zambiri amayesa kaye ngati muli ndi 'hungry bone syndrome' mwa kuyesa magazi a calcium. Nthawi zambiri, ngati calcium m'magazi mwanu ili pansi pa 8.4 mg/dL kwa masiku opitilira anayi, imaonedwa kuti ndi chiopsezo cha 'hungry bone syndrome'.

Si zokhazo, komanso dokotala wanu angachite mayeso ena angapo kuti aone ngati vutoli lakhudza mbali zina za thanzi lanu:

• Mayeso ena a magazi: Magazi anu angayesedwe kuti aone ngati ali ndi magnesium, phosphorous, parathyroid hormone (PTH), ndi/kapena milingo ya vitamini D.
• EKG (Electrocardiogram): Kuyeza kumeneku kumayesa kayimbidwe ka mtima wanu polumikiza ma electrode pachifuwa chanu. Izi ndizofunikira chifukwa calcium yochepa m'magazi (hypocalcemia) ndi 'hungry bone syndrome' zingayambitse kugunda kwa mtima kosakhazikika.
• Mayeso ojambulira mafupa: Mayesowa amatha kuwona mavuto omwe ali m'mafupa anu, monga kusweka kwa mafupa, kupunduka kwa mafupa, kapena zotupa.

Kodi mankhwala a 'Hungry Bone Syndrome' ndi ati?

Musadandaule, pali mankhwala abwino a izi. Cholinga chachikulu cha chithandizo ndikubwezeretsa calcium m'magazi anu kukhala abwino. Nthawi zambiri, mudzalandira chithandizochi muli kuchipatala. Chithandizo chingaphatikizepo:

• Kupereka calcium kudzera m'mitsempha (`(IV Calcium - Calcium Gluconate)`): Izi zimathandiza kubwezeretsa msanga kuchuluka kwa calcium.
• Zakudya Zowonjezera za Calcium (Calcium Citrate kapena Calcium Carbonate): Izi zimaperekedwa kuti zisunge calcium yambiri.
• Zakudya Zowonjezera za Vitamini D: Vitamini D ndi yofunika kwambiri kuti thupi lizitha kuyamwa calcium.
• Kubwezeretsa Magnesium: Ngati magnesium ili yochepa, nayonso iyenera kukonzedwa.

Madokotala adzafufuza matenda anu ndikupeza chithandizo choyenera kwambiri kwa inu.

Kodi zitenga nthawi yayitali bwanji kuti munthu achire ku vutoli? Kodi tsogolo lake ndi lotani?

Nkhani yabwino ndi yakuti vuto ili, 'Hungry Bone Syndrome', limatha kuchiritsidwa kwathunthu . Izi zikutanthauza kuti chiyembekezo cha matendawa ndi chabwino kwambiri.

Komabe, ngakhale mutalandira chithandizo, nthawi yomwe imatenga kuti vutoli lithe kwathunthu imatha kusiyana. Anthu ena amachira pakatha masiku ochepa, pomwe ena angatenge miyezi ingapo. Nthawi zina, zimatha mpaka chaka chimodzi.

Chofunika kwambiri n’chakuti, ngati sichikuthandizidwa, kuchepa kwa calcium m’thupi kungayambitse mavuto oopsa monga khunyu. Chifukwa chake, ndikofunikira kupeza chithandizo mwamsanga ngati zizindikiro zayamba.

Kodi 'Hungry Bone Syndrome' ingapewedwe?

Popeza 'hungry bone syndrome' imatha kuchitika pambuyo pa opaleshoni ya parathyroid (`(Parathyroidectomy)`) kapena opaleshoni ya chithokomiro (`(Chithokomiro)`), madokotala amayesetsa kuchitapo kanthu kuti apewe ngakhale opaleshoni isanachitike. Tiyeni tiwone zomwe zili:

• Kuwunika musanachite opaleshoni: Dokotala wanu asanachite opaleshoni , adzayang'ana kuchuluka kwa mchere m'mafupa anu, kuchuluka kwa calcium m'magazi, kuchuluka kwa phosphate, kuchuluka kwa PTH, ndi kuchuluka kwa vitamini D. Mayesowa angathandize dokotala wanu kudziwa ngati muli pachiwopsezo chotenga 'hungry bone syndrome'.
• Njira zodzitetezera:Ngati muli pachiwopsezo chachikulu chotenga 'hungry bone syndrome', dokotala wanu angakulangizeni kuti mumwe mankhwala owonjezera kapena mankhwala kuti mukhalebe ndi vitamini D ndi calcium musanayambe opaleshoni. Izi zingathandize kuchepetsa mwayi ndi/kapena kuopsa kwa 'hungry bone syndrome'.
• Kuwunika pambuyo pa opaleshoni: Pambuyo pa opaleshoni, gulu la chipatala lidzayang'ana nthawi zonse kuchuluka kwa calcium, phosphate, magnesium, ndi PTH m'magazi mwanu. Izi zili choncho kuti ngati mutayamba 'hungry bone syndrome', izi zitha kuzindikirika msanga ndipo chithandizo chiyambe nthawi yomweyo.

Komabe, ngakhale kuti pali njira zonsezi, nthawi zina 'hunger bone syndrome' imatha kuyamba. Ofufuza sakudziwabe chifukwa chake izi zimachitika.

Ndiyenera kupita kwa dokotala nthawi yanji?

Ngati mwachitidwa opaleshoni ya parathyroid kapena thyroid kenako n’kuyamba kukhala ndi zizindikiro za calcium yochepa m’magazi (`(Hypocalcemia)`) zomwe tidakambirana kale, monga kupweteka kwa minofu, kumva kufooka, kusintha kwa chikumbumtima (monga kusokonezeka), komanso dzanzi la milomo ndi zala, muyenera kuwonana ndi dokotala mwamsanga.** 'Hungry bone syndrome' ndi '(Hypocalcemia)` zimatha kuchitika pambuyo pa opaleshoni ya parathyroid ndi/kapena thyroid, zimatha kutha patatha masiku angapo, kenako n’kubwereranso. Chifukwa chake, ndikofunikira kwambiri kulabadira ngakhale chizindikiro chochepa kwambiri.

'Hungry bone syndrome' ndi matenda omwe angachitike mutachita opaleshoni yochotsa parathyroid kapena thyroid glands. Nkhani yabwino ndi yakuti amatha kuchiritsidwa ndikuchiritsidwa. Komabe, zingatenge nthawi kuti achire bwino. Popeza kuchepa kwakukulu kwa calcium m'magazi kungakhale koopsa pa thanzi lanu, ndi bwino kupita kwa dokotala mukangoona zizindikiro.

Tenga uthenga kunyumba

Mwachidule, 'Hungry Bone Syndrome' ndi vuto lomwe limatha kuchitika pambuyo pa opaleshoni ya parathyroid kapena thyroid gland. Chomwe chimachitika kwenikweni ndichakuti kuchuluka kwa calcium m'magazi a thupi kumachepa mwadzidzidzi. Izi zili choncho chifukwa kuchuluka kwa parathyroid hormone (`(PTH)`) kumachepa pambuyo pa opaleshoni, zomwe zimapangitsa mafupa "kufuna" calcium.

Musaope kumva izi, chifukwa 'Hungry Bone Syndrome' ndi vuto lomwe lingachiritsidwe bwino.

Chofunika kwambiri ndichakuti ngati muli ndi zizindikiro izi (monga kugwedezeka kwa minofu, kutopa, dzanzi), musataye nthawi ndikupita kwa dokotala mwachangu momwe mungathere. Mwanjira imeneyi, mutha kuzindikira vutoli msanga, kuyamba chithandizo chofunikira mwachangu, ndikuchira lisanakhale vuto lalikulu. Kumbukirani, kusamalira thanzi lanu kuli m'manja mwanu.

'Matenda a Njala, Matenda a Njala, Calcium, Hypocalcemia, Parathyroid, Opaleshoni ya Chithokomiro, PTH