Kodi kusintha kumeneku m'thupi lanu kumachitika chifukwa cha histamine? Tiyeni tidziwe bwino!

Kodi mwadzidzidzi mumamva kuyabwa? Kodi mumayesa mutatha kuyetsemula? Kapena mumamva ziphuphu zofiira pathupi panu pakapita nthawi mutadya zakudya zina? Mwina zinthuzi zachitikanso kwa inu. Nthawi zambiri, munthu amene ali ndi vutoli amatchedwa histamine. Lero, tiyeni tikambirane za histamine, chifukwa chake ndi yofunika m'thupi lathu, komanso zomwe zimachitika ikawonjezeka.

Kodi histamine kwenikweni ndi chiyani?

Mwachidule, histamine ndi mankhwala omwe amapezeka mwachibadwa m'matupi athu. Ali ngati kamtumiki kakang'ono komwe kamagwira ntchito m'matupi athu. Amasungidwa mkati mwa maselo ena m'matupi mwathu. Amasungidwa makamaka m'mitundu iwiri ya maselo otchedwa mast cells ndi basophils . Maselo awa ndi gawo la chitetezo chathu chamthupi, dongosolo lomwe limatiteteza ku matenda. Taganizirani ngati linga. Mdani (monga nyongolosi kapena mungu) akabwera kuchokera kunja kwa linga ili, alonda monga mast cells awa amagwiritsa ntchito chida chotchedwa histamine kuti ayambe nkhondo. Sikuti zokhazo, komanso mnzathu uyu wotchedwa histamine nayenso amagwira ntchito pothandiza m'mimba mwathu kugaya chakudya komanso mu ntchito zina za ubongo.

N’chifukwa chiyani histamine iyi imatuluka m’thupi lathu?

Chifukwa chachikulu chomwe histamine imatulutsidwira m'thupi ndi zomwe zimachitika chifukwa cha ziwengo . Tiyeni tiwone momwe zimachitikira. 1. Ziwengo: Tangoganizani kuti muli ndi ziwengo chifukwa cha fumbi. Mukapita pamalo pomwe pali fumbi, tinthu ta fumbi (timene timati allergens ) timalowa m'mphuno mwanu. Kenako maselo a mast m'thupi lathu amazindikira tinthu ta fumbi ngati "mdani". Amawazindikira ndikuyamba kuwagwira. Panthawiyi, histamine mkati mwa maselo a mast imatulutsidwa mwadzidzidzi. Monga bomba likuphulika. Histamine iyi ndi yomwe imayambitsa kuyetsemula, mphuno yotsekeka, ndi maso oyabwa.

• Zina mwa zinthu zomwe zimayambitsa allergen ndi izi:
• Mungu
• Nthata za fumbi
• Nsalu ya nyama
• Zakudya zina (monga mkaka, mazira , mtedza , nsomba )
• Kuluma ndi tizilombo
• Mankhwala ena

2. Kuvulala kapena Matenda: Thupi likavulala, khungu likasweka, kapena kachilombo kamene kamalowa, histamine imatulutsidwa. Histamine imathandiza kuwonjezera kuyenda kwa magazi kupita kumalo komwe kuvulalako, kubweretsa zinthu zofunika ndi maselo olimbana ndi tizilombo kuti athandize kuchiritsa bala.

Kodi histamine imachita chiyani m'thupi?

Histamine ikatulutsidwa m'thupi, imapita ku ziwalo zosiyanasiyana za thupi lathu ndipo imakhala ndi zotsatira zosiyanasiyana.

• Mitsempha yamagazi : Histamine imapangitsa kuti mitsempha yamagazi yaying'ono m'thupi lathu ikule. Izi zimatchedwa vasodilation . Izi zimapangitsa kuti magazi ambiri ayende kudzera m'mitsemphamo. Ichi ndichifukwa chake nthawi zina mukakhala ndi vuto la ziwengo, khungu lanu limafiira ndipo mumamva kutentha. Komanso, madzi amayamba kutuluka m'makoma a mitsempha yamagazi. Izi zimayambitsa kutupa (Kutupa/ Kutupa ), mphuno yotuluka madzi , ndi maso otuluka madzi.
• Matupi a m'mapapo : Histamine imapangitsa minofu ya m'mapapo kufooka. Izi zimatchedwa bronchoconstriction . Izi zimapangitsa kuti kupuma kukhale kovuta komanso chifuwa chikhale cholimba, makamaka kwa anthu omwe ali ndi mphumu .
• Khungu: Histamine imatha kuyambitsa mitsempha ya pakhungu ndikuyambitsa kuyabwa/kutupa. Imayambitsanso kuoneka kwa ziphuphu zofiira komanso zotupa (hives/urticaria) pakhungu.
• M'mimba: Kuchepa kwa minofu m'matumbo kungayambitse kupweteka m'mimba, nseru, kusanza, ndi kutsegula m'mimba. Histamine imathandizanso kulimbikitsa kutulutsa asidi m'mimba.
• Dongosolo la mitsempha: Histamine imagwiranso ntchito ngati cholumikizira mitsempha muubongo. Izi zikutanthauza kuti imathandiza kunyamula mauthenga pakati pa maselo amitsempha. Izi zimathandiza kwambiri kuti tikhale maso komanso atcheru. (Ndicho chifukwa chake mankhwala ena akale a ziwengo amatipangitsa kugona tulo, chifukwa amachepetsanso ntchito ya histamine muubongo.)

Kodi zizindikiro za kuchuluka kwa histamine ndi ziti?

Zizindikiro za kuchuluka kwa histamine zimatha kusiyana malinga ndi munthu aliyense, kutengera kuchuluka kwa histamine yomwe yatulutsidwa komanso chiwalo chomwe chakhudzidwa kwambiri.

• Zizindikiro za khungu:
• Kufiira kwa khungu, kuyabwa
• Eczema, ziphuphu
• Urticaria/Hives: Zilonda za pakhungu zomwe zimayabwa mwadzidzidzi, zofiira, zotupa, komanso zotupa kwambiri.
• Zizindikiro za mphuno ndi pakhosi:
• Kutsimula
• Kutsekeka kwa mphuno kapena kutsekeka kwa mphuno
• Mphuno, pakhosi, ndi mkamwa kuyabwa
• Chifuwa
• Kutupa kwa pakhosi, kusintha kwa mawu
• Zizindikiro zokhudzana ndi maso:
• Maso ofiira, oyabwa
• Misozi ikutuluka m'maso
• Kutupa kwa zikope
• Zizindikiro zokhudzana ndi mapapo:
• Kuvuta kupuma, kupuma movutikira
• Kumva kupsinjika pachifuwa
• Kupuma movutikira (kuimba mluzu)
• Ngati muli ndi mphumu, kuwonjezereka kwa mphumu
• Zizindikiro zokhudzana ndi kugaya chakudya:
• Kusanza, kusanza
• Kupweteka m'mimba, kutupa
• Kutsegula m'mimba
• Zina mwazinthu:
• Mutu (kupweteka mutu)
• Chizungulire
• Kuthamanga kwa magazi kotsika (makamaka pakakhala zovuta kwambiri)

Tangoganizani kuti mnzanu Sugath wadya nkhanu. Pasanathe theka la ola, thupi lake lonse linali kuyabwa ndipo anali ndi ziphuphu zofiira. Anali kuvutika kupuma. Izi zitha kukhala chifukwa thupi la Sugath mwadzidzidzi linatulutsa histamine yambiri chifukwa cha nkhanuyo.

Vuto loopsa kwambiri: Anaphylaxis

Imeneyi ndi njira yowopsa kwambiri komanso yowopsa kwambiri yolimbana ndi histamine. Izi zimatchedwa anaphylaxis . Pamenepa, histamine yambiri imatulutsidwa m'thupi lonse nthawi imodzi. Izi zitha kuchitika mkati mwa mphindi zochepa. Zizindikiro zazikulu za anaphylaxis ndi izi:

• Kuvuta kwambiri kupuma (kutseka njira yopumira chifukwa cha kutupa kwa pakhosi ndi lilime)
• Chizungulire, kumva kukomoka
• Kugunda kwa mtima
• Kutsika mwadzidzidzi kwa kuthamanga kwa magazi
• Chisokonezo
• Khungu labuluu kapena lotumbululuka

Ngati muwona chimodzi mwa zizindikirozi, ndi vuto lachipatala. Muyenera kupita kuchipatala nthawi yomweyo. Kuchedwetsa chithandizo kungakhale koopsa. Chithandizo choyamba pazochitika zotere ndi jakisoni wa adrenaline (Adrenaline/Epinephrine) .

Kodi mungatani kuti muchepetse zotsatira za histamine?

Mwamwayi, tili ndi njira zothanirana ndi kusasangalala kumeneku komwe kumachitika chifukwa cha histamine. 1. Mankhwala oletsa kugwidwa ndi histamine: Uwu ndiye mtundu waukulu wa mankhwala. Mankhwalawa amatseka malo omwe histamine imalumikizana (otchedwa histamine receptors) . Izi zimaletsa histamine kuti isagwire ntchito.

• Mankhwala oletsa kutupa a m'badwo woyamba: Izi zingayambitse kugona tulo (monga chlorpheniramine, diphenhydramine). Chifukwa chake, muyenera kusamala mukamawamwa usiku kapena mukamachita ntchito monga kuyendetsa galimoto.
• Mankhwala oletsa kutupa a m'badwo wachiwiri: Awa sagona mokwanira (monga Loratadine, Cetirizine, Fexofenadine). Ndi bwino kugwiritsa ntchito masana.

Dokotala adzasankha mankhwala oletsa kutupa omwe ali oyenera kwa inu komanso nthawi yomwe muyenera kumwa.Mankhwalawa amagwira ntchito poletsa kutulutsidwa kwa histamine kuchokera ku maselo a mast. (Chitsanzo: Cromolyn sodium). Mankhwalawa amabwera ngati ma spray a m'mphuno ndi madontho a m'maso. 3. Corticosteroids: Awa ndi mankhwala amphamvu omwe amachepetsa kutupa. Nthawi zina, amagwiritsidwa ntchito kwakanthawi kochepa kuti athetse mphumu m'mikhalidwe yovuta kwambiri ya ziwengo. 4. Kupewa zinthu zomwe zimayambitsa ziwengo: Ngati mukudziwa zomwe muli nazo, ndi bwino kupewa zinthu zimenezo momwe mungathere. Mwachitsanzo, ngati muli ndi ziwengo ku fumbi, mutha kuchita zinthu monga kusunga nyumba yanu yoyera komanso kuvala chigoba mukatuluka panja nthawi ya mungu.

Kodi Kusalolera kwa Histamine ndi Chiyani?

Izi n’zosiyana pang’ono ndi vuto la ziwengo. Kusalolera histamine kumachitika pamene thupi lathu silingathe kugawa bwino histamine kuchokera ku chakudya kapena kuchuluka kwa histamine komwe kumapangidwa m’thupi. Chifukwa chachikulu cha izi ndi kuchepa kwa enzyme Diamine Oxidase (DAO) . Pankhaniyi, zizindikiro zomwezo monga za ziwengo (kuyabwa, mutu, mavuto am’mimba) zimatha kuchitika. Komabe, izi zimachitika mukadya zakudya zokhala ndi histamine yambiri (monga tchizi chakale, zakudya zowiritsa, vinyo, ndiwo zamasamba ndi zipatso). Ngati muli ndi kukayikira kulikonse pa izi, ndi bwino kuonana ndi dokotala ndikulankhula naye.

Kodi muyenera kupita kwa dokotala liti?

Kawirikawiri, palibe vuto kugula mankhwala oletsa kutupa ku pharmacy ngati muli ndi zizindikiro zazing'ono za ziwengo. Komabe, pazochitika ngati izi, muyenera kuonana ndi dokotala:

• Ngati nthawi zambiri mumakhala ndi zizindikiro zoopsa za ziwengo.
• Ngati zizindikiro sizikulamuliridwa ndi mankhwala wamba.
• Ngati mukumva kuvutika kupuma kapena chifuwa chanu chikulimba.
• Ngati mukukumana ndi zizindikiro zilizonse za anaphylaxis (izi ndi zadzidzidzi!).
• Ngati mukufuna kudziwa bwino zomwe zili ndi vuto la ziwengo (pali mayeso a ziwengo ).
• Ngati pali kukayikira kuti histamine siigwirizana ndi mankhwala enaake.

Dokotala akhoza kuwunika bwino matenda anu ndikukupatsani chithandizo chabwino kwambiri komanso upangiri womwe mukufuna.

Pomaliza, zinthu zoti muzikumbukira (Uthenga Wopita Nawo Kunyumba)

Choncho, ngakhale kuti histamine ndi mankhwala ofunikira m'thupi lathu, nthawi zina ingakhale yovuta pang'ono.

• Histamine imagwira ntchito yofunika kwambiri pa matenda a ziwengo, komanso imathandiza pakuchiritsa mabala ndi ntchito ya m'mimba.
• Zinthu monga kuyetsemula, kuyabwa kwa khungu, ziphuphu, ndi kutsekeka kwa mphuno zimatha kuyambitsidwa ndi histamine.
• Anaphylaxis ndi vuto loopsa kwambiri lomwe limayamba chifukwa cha histamine. Ndi vuto lachipatala lomwe limafuna chithandizo chadzidzidzi.
• Mankhwala oletsa histamine ndi mankhwala akuluakulu omwe amawongolera zotsatira za histamine.
• Ngati muli ndi zizindikiro zobwerezabwereza kapena zoopsa za ziwengo, onetsetsani kuti mwapeza upangiri wa dokotala.

Palibe chodetsa nkhawa nacho. Matenda ambiri okhudzana ndi histamine amatha kuthetsedwa bwino. Chofunika kwambiri ndikusamala thupi lanu ndikupempha upangiri woyenera wa dokotala ngati pakufunika kutero. histamine, ziwengo, ziwengo, antihistamine, anaphylaxis, urticaria, mphumu, ஹிஸ்டின், அல்ஜி, அல்ஜி