Tiyeni tiphunzire za matenda osowa omwe amakhudza mafupa ndi khungu lanu? (Maffucci Syndrome)

Kodi mudamvapo za matenda achilendo omwe amayambitsa mavuto m'mafupa anu mwadzidzidzi, ndipo nthawi zina khungu lanu? Mwina mwawonapo chinthu chonga fupa likutuluka m'dzanja kapena mwendo wanu, kapena madontho ofiira kapena ofiirira pakhungu lanu. Ndicho chimene tikambirane lero, vuto lovuta pang'ono, komanso losowa kwambiri. Limatchedwa `(Maffucci Syndrome)`. Musadandaule, tikambirana mwachidule, m'njira yomwe mungamvetse.

Ndiye kodi Maffucci Syndrome imeneyi ndi chiyani?

Mwachidule, Maffucci Syndrome ndi matenda osowa kwambiri omwe amakhudza mafupa ndi khungu lanu. Amakhudza zinthu zitatu zazikulu:

1. Chipolopolo chimakula kwambiri mkati mwa mafupa anu. Chipolopolochi ndi minofu yolimba komanso yosinthasintha yomwe imaphimba madera monga mafupa anu. Izi zikakula kukhala zotupa mkati mwa mafupa anu, timazitcha kuti `enchondromas`. Izi si khansa (zoipa), zomwe zikutanthauza kuti sizili zoopsa poyamba. Komabe, mazana, kapena zikwizikwi, za `enchondromas` izi zimatha kupangika.

2. `(enchondromas)` izi zimayambitsa kufooka kwa mafupa. Tangoganizirani, ngati chinachake chikukulira mkati mwa fupa mosafunikira, mawonekedwe a fupalo amasintha, sichoncho? Umu ndi momwe zilili. Zinthu monga kufupikitsa miyendo, kutambasula, ndi kusweka kwa mafupa zimatha kuchitika .

3. Ma hemangioma ndi ziphuphu zomwe zimawoneka ngati mitsempha yamagazi yosagwirizana bwino yomwe imalumikizana pamwamba pa khungu. Izi zimatha kuoneka zofiira, zabuluu, kapena zofiirira.

Zomera za cartilage izi, zotchedwa enchondromas, zimapezeka kwambiri m'mafupa a zala zanu ndi zala zanu. Komabe, zimathanso kukhudza madera otsatirawa:

• Manja
• Miyendo
• Nthiti
• Chigaza
• Msana wa msana (vertebrae)

Chofunika kwambiri n'chakuti, ma enchondroma amenewa poyamba si a khansa (oipa), koma nthawi zina amatha kukhala oopsa (oopsa). Anthu ambiri omwe ali ndi matenda a Maffucci (mpaka 50% malinga ndi kafukufuku wina) ali pachiwopsezo chachikulu chotenga khansa ya m'mafupa yotchedwa chondrosarcoma, yomwe imayamba m'maselo a cartilage. Alinso pachiwopsezo chachikulu chotenga mitundu ina ya khansa.

Kodi matenda a Maffucci ndi ofala bwanji?

Ndipotu, vutoli ndi losowa kwambiri. Pali milandu yokwana mazana angapo yomwe yalembedwa m'mabuku azachipatala padziko lonse lapansi, kotero sizodabwitsa ngati simunamvepo za vutoli kale.

Kodi zizindikiro za Maffucci Syndrome ndi ziti?

Zizindikiro za matenda a Maffucci zimatha kusiyana malinga ndi munthu. Anthu ena akhoza kukhala ndi zizindikiro zochepa kwambiri, pomwe ena akhoza kukhala ndi zizindikiro zoopsa kwambiri. Zizindikirozi zitha kupezeka pobadwa, kapena zingayambe kuonekera ali ana.

Zizindikiro zazikulu zimayambitsidwa ndi zotupa za cartilage zomwe tidalankhula zotchedwa ``enchondromas.'' Zingayambitse zinthu monga:

• Kupweteka kwa mafupa
• Kusweka kwa mafupa - Fupa limatha kusweka ngakhale litagwa pang'ono.
• Manja kapena miyendo yowerama
• Mafupa otupa - amawoneka ngati ziphuphu.
• Msana wopindika - wofanana ndi scoliosis.
• Osteolysis ( kuwonongeka kwa mafupa )
• Kutalika kwaufupi
• Manja kapena miyendo yosafanana - imodzi imawoneka yayitali kapena yayifupi kuposa inzake.

Matenda a mitsempha yamagazi, otchedwa hemangiomas, angayambitse zizindikiro monga:

• Magazi amaundana
• Lymphangiomas - Izi zili ngati mikwingwirima yodzaza ndi madzi a lymph.
• Matumbo ofiira, ofiirira, kapena abuluu pakhungu (hemangiomas) - omwe amapezeka kwambiri m'manja. Pakapita nthawi, awa amatha kukhala olimba komanso otupa.
• Minofu yosakula bwino - m'dera lokhudzidwa.

Kodi n’chiyani chimayambitsa matenda a Maffucci?

Matenda a Maffucci ndi matenda a majini. Izi zikutanthauza kuti amayamba chifukwa cha kusintha (kusintha) kwa majini athu. Makamaka, amayamba chifukwa cha kusintha kwachisawawa kwa majini awiri otchedwa `IDH1` (ofala kwambiri) kapena `IDH2` (kawirikawiri). Ofufuza amakhulupirira kuti kusintha kwa majini kumeneku kumachitika mwana akadali m'mimba, kutanthauza, asanabadwe. Majini a `IDH` amenewa amathandiza kupanga `(ma enzyme)` omwe ndi ofunikira pakugwira ntchito kwa maselo m'thupi lathu. Komabe, asayansi sanathe kupeza ubale weniweni pakati pa `(ma enzyme)` awa ndi matenda a Maffucci.

Chofunika kwambiri ndichakuti matenda amenewa si obadwa nawo. Izi zikutanthauza kuti, si matenda omwe angaperekedwe kuchokera ku mibadwomibadwo chifukwa makolo awo anali nawo. Uwu ndi kusintha kwa majini mwachisawawa.

Kodi matenda a Maffucci amawapeza bwanji?

Mayeso awa angathandize dokotala kuzindikira matenda a Maffucci:

• Kuyezetsa thupi: Dokotala adzakuyezetsani ndikuyang'ana zizindikiro zilizonse zomwe zikuoneka (monga zotupa kapena zofooka). Adzakufunsaninso za zizindikiro zanu komanso ngati pali wina aliyense m'banja mwanu amene wakhala ndi matenda ofanana ndi anu.
• Kujambula X-ray kapena CT scan: Izi zimatha kujambula zithunzi zomveka bwino za mafupa anu. Kenako zimatha kuwona ngati pali ma enchondromas, momwe afalikira, komanso ngati pali kuwonongeka kulikonse kwa mafupa.
• Kutenga zitsanzo za minofu kudzera mu opaleshoni ndikuzifufuza (`Biopsy`):Nthawi zina, kachidutswa kakang'ono ka minofu kamachotsedwa opaleshoni pamalo okayikitsa (monga fupa kapena chotupa cha pakhungu) ndikukayang'aniridwa ndi maikulosikopu. Ichi ndi chomwe chimapangitsa kuti chikhale chotsimikizika.

Ndi akatswiri otani omwe amachiritsa matenda a Maffucci?

Ngati muli ndi matenda a Maffucci, gulu la akatswiri osiyanasiyana lingakumane kuti likuthandizeni. Mwachitsanzo:

• Dokotala wa khungu: Amathandiza kuchiza, kuchepetsa, kapena, ngati kuli kofunikira, kuchotsa zotupa pakhungu monga hemangiomas.
• Dokotala wa mafupa: Amachiritsa mafupa osweka, amakonza mafupa ofooka, komanso amatha kuchotsa mafupa osweka.
• Katswiri wa khansa ya mafupa: Ngati khansa ngati chondrosarcoma yomwe tidakambirana kale iyamba, madokotala awa amathandiza kuichotsa ndikuyang'anira matendawa moyo wonse kuti aone ngati ibwereranso.
• Katswiri wa za radi: Amagwira ntchito yojambula zithunzi zachipatala, monga X-ray ndi CT scans, ndipo ndi ofunikira poyesa kusintha kwa mafupa pakapita nthawi.

Kodi matenda a Maffucci amachiritsidwa bwanji?

Kunena zoona, palibe njira yochiritsira matenda a Maffucci kwathunthu pakadali pano. Chifukwa chake, zolinga zazikulu za chithandizo ndi izi:

• Kuzindikira khansa msanga ndikupereka chithandizo chothandiza kwambiri.
• Kuteteza kapena kuchiza kusweka kwa mafupa.
• Kuchepetsa zizindikiro monga ululu.

Gulu lanu lachipatala nthawi zambiri limayitanitsa mayeso a zachipatala (monga X-ray) kuti liwunikire mafupa anu. Ngati mavuto a enchondroma kapena mafupa akusokoneza zochita zanu za tsiku ndi tsiku, chithandizo chingaphatikizepo:

• Kuvala zomangira zitsulo kapena kuchitidwa opaleshoni kuti akonze scoliosis.
• Ma cast, ma splints, ndi opaleshoni ya mafupa osweka.
• Chepetsani kusiyana kwa kutalika kwa miyendo ndi nsapato zapadera (zokweza nsapato), mankhwala, kapena opaleshoni.
• Opaleshoni yokonza zolakwika m'manja.
• (Enchorma) ikhoza kuchotsedwa opaleshoni. Komabe, izi zitha kubwereranso.

Ngati hemangiomas pakhungu lanu ikuvutitsa, dokotala wanu angakulangizeni chithandizo chotchedwa sclerotherapy. Izi zimaphatikizapo kubaya jakisoni wamadzimadzi pakhungu kuti muchepetse kukula. Ngati pakufunika kutero, hemangiomas ikhoza kuchotsedwa opaleshoni.

Kodi matenda a Maffucci angapewedwe?

Monga tafotokozera kale, asayansi sakumvetsa bwino momwe kusintha kwa majini komwe kumayambitsa izi kumachitikira. Chifukwa chake, pakadali pano palibe njira yeniyeni yopewera izi.

Kodi tsogolo la munthu amene ali ndi matenda a Maffucci ndi lotani?

Matenda a Maffucci ndi matenda osatha, omwe amakhudza moyo wonse. Anthu ena amakhala ndi mavuto ang'onoang'ono akuthupi, omwe sangakhudze kwambiri zochita zawo za tsiku ndi tsiku. Komabe, kwa ena, mavuto a mafupa angakhale aakulu kwambiri, ndipo zofooka za thupi zingawonjezereke.

Chofunika kwambiri n'chakuti vutoli silikhudza nzeru. Komabe, ngati khansa iyamba, pali mwayi woti ingachepetse moyo wa munthu.

Kodi ndimadzisamalira bwanji ine ndekha monga munthu amene ali ndi matenda a Maffucci?

Popeza anthu omwe ali ndi matenda a Maffucci ali pachiwopsezo chachikulu chotenga khansa, ndikofunikira kuti muyezedwe nthawi zonse monga momwe gulu lanu lachipatala likulangizira. Khansa ikapezeka msanga, m'pamenenso imakhala ndi mwayi wochira.

Kodi pali kusiyana kotani pakati pa Ollier Syndrome ndi Maffucci Syndrome?

Matenda a Ollier ndi matenda a Maffucci ndi matenda omwe amachititsa kuti ziphuphu za cartilage zotchedwa enchondroma ziyambe kukula. Komabe, mu matenda a Maffucci, ziphuphu za mitsempha yamagazi zotchedwa hemangiomas zimawonekeranso. Matenda a Ollier alibe hemangiomas. Ndi kusiyana kwakukulu kumeneku.

Kodi pali mayina ena a matenda a Maffucci?

Popeza matendawa ndi osowa kwambiri, nthawi zina amatchedwa ndi mayina ena, koma si ofala kwambiri. Nazi zitsanzo zina:

• `(Chondrodysplasia yokhala ndi hemangioma)`
• `(Dyschondroplasia ndi cavernous hemangioma)`
• `(Enchondromatosis yokhala ndi hemangiomata)`
• `(Kast syndrome)`

Ngakhale pali mayina ambiri ngati awa, dzina lomwe limagwiritsidwa ntchito kwambiri ndi Maffucci Syndrome.

Pomaliza, uthenga wopita nawo kunyumba

Ngati inu kapena mwana wanu mwapezeka ndi matenda a Maffucci Syndrome, zingakhale zovuta kwambiri. Muyenera kuda nkhawa ndi kusweka kwa mafupa ndi khansa ya mafupa kwa moyo wanu wonse. Zingakhalenso zotopetsa kuonana ndi akatswiri osiyanasiyana komanso kuyesedwa pafupipafupi.

Koma, kusamala motere, makamaka kuyezetsa khansa msanga, kungathandize kwambiri pakupulumutsa kapena kukulitsa moyo wanu. Kuzindikira ndi kuchiza khansa msanga ndiyo njira yabwino kwambiri yowonjezerera thanzi lanu. Dokotala wanu adzakuuzani zizindikiro zomwe muyenera kusamala nazo.

Musadandaule. Simuli nokha. Pali madokotala ndi magulu othandizira kuti athandize ndikutsogolera anthu omwe ali ndi matenda osowawa. Chofunika kwambiri ndikupeza chidziwitso choyenera ndikutsatira malangizo a dokotala wanu.

Matenda a Maffucci, matenda a mafupa, cartilage, hemangioma, chiopsezo cha khansa, matenda a majini, matenda osowa