Kodi odwala impso amadziwa izi akalandira MRI? Tiyeni tikambirane za Nephrogenic Systemic Fibrosis (NSF)!

Kodi muli ndi vuto lililonse la impso? Kapena dokotala wakuuzani kuti impso zanu sizikugwira ntchito bwino? Nthawi zina, mukayenera kuyesedwa ngati Magnetic Resonance Imaging (MRI), muyenera kusamala pang'ono ndi utoto wapadera womwe mumagwiritsa ntchito. Lero, tikambirana za vuto lomwe lingachitike nthawi ngati zimenezi, koma ndi losowa kwambiri tsopano, koma ndi lofunika kudziwa. Izi zimatchedwa Nephrogenic Systemic Fibrosis (NSF).

Kodi NSF (Nephrogenic Systemic Fibrosis) iyi ndi chiyani? Mwachidule...

Mwachidule, Nephrogenic Systemic Fibrosis (NSF) ndi vuto losowa kwambiri. Limapezeka makamaka mwa anthu omwe ali ndi matenda a impso, makamaka omwe ali ndi vuto la impso. Vutoli limatha kuchitika munthu akapatsidwa mankhwala osiyanitsa a gadolinium (GBCAs) panthawi yojambula, monga MRI, kuti zithunzi ziwonekere bwino.

Taganizirani izi, impso zathu ndi zomwe zimasefa zinthu zosafunikira m'thupi lathu ndikuzitulutsa ndi mkodzo. Chifukwa chake, pamene izi zotchedwa ``GBCAs'' zilowa m'thupi la munthu amene impso zake sizikugwira ntchito bwino, sizichotsedwa bwino m'thupi. Pamenepo ndi pomwe chiopsezo cha NSF chimayamba.

Kodi mukudziwa chomwe chimayambitsa NSF? Khungu lanu likhoza kukhala lolimba, lolimba, lotupa, komanso loyabwa. Nthawi zina, ngakhale mafupa amatha kuuma ndikukhala pamalo amodzi. Izi zimatchedwa "joint contracture". Sikuti zokhazo, komanso mwa anthu ena, vutoli lingakhudzenso ziwalo mkati mwa thupi, monga minofu ya pachifuwa, mtima, ndi mapapo. Chomwe chimachitika ndichakuti minofu yozungulira ziwalozo imakhuthalanso ndikukhala yolimba.

Chofunika kwambiri ndichakuti, NSF ikachitika, pakadali pano palibe chithandizo chomveka bwino choiletsa kapena kuisintha.

Koma, musadandaule! Ngakhale bungwe la US Food & Drug Administration (FDA) lalangiza mwamphamvu kuti zisagwiritsidwe ntchito ma GBCA ena akale mwa odwala impso. Ma GBCA atsopano omwe ali pamsika sananenedwe kuti amayambitsa NSF mwa odwala impso. Ndi mpumulo waukulu.

Kodi NSF ndi yofala bwanji masiku ano?

Ndipotu, ndi zachilendo kwambiri tsopano. Ndipotu, palibe milandu yatsopano ya NSF yomwe yanenedwa m'zaka zoposa 10. Pambuyo pa 2006, pamene madokotala adadziwa za kugwirizana pakati pa ``(GBCAs)`` ndi matenda a impso, chiwerengero cha malipoti a matendawa chinachepa kwambiri.

Kodi matenda a NSF amayamba bwanji? Kodi zizindikiro zake ndi ziti?

Zizindikiro za NSF zitha kuonekera tsiku lomwelo lomwe mankhwala oletsa kusiyanitsa omwe ali ndi gadolinium (GBCAs) amalowetsedwa m'thupi. Kapena, zitha kuonekera miyezi ingapo pambuyo pake. Mu kafukufuku wina, pafupifupi 50% ya anthu adayamba zizindikiro mkati mwa masiku 12.

Zizindikiro zazikulu zomwe zingawonekere ndi izi:

• Kutupa, kulimba, ndi kukhuthala kwa khungu: Izi nthawi zambiri zimakhudza madera monga manja, miyendo, chifuwa ndi mimba. Nkhope simakhudzidwa kawirikawiri.
• Madontho akuda kapena zipsera pakhungu: Nthawi zina khungu limatha kukhala louma, ngati khungu la lalanje.
• Khungu likumva kuyabwa, kutupa, kapena kupweteka.
• Kulephera kusuntha miyendo ndi malo olumikizirana mafupa nthawi zonse chifukwa cha kukhuthala ndi kutupa kwa khungu.

Kwa anthu ena, zizindikirozi zingakhudzenso ziwalo zamkati ndi minofu ya thupi. Nazi zina zomwe mungakumane nazo:

• Kufooka kwakukulu kwa minofu.
• Chifukwa cha minofu yolimba, miyendo singathe kupindika bwino kapena kutambasulidwa (monga, kuchuluka kwa mayendedwe kumachepa).

Ngati fibrosis iyi, kapena kukhuthala kwa minofu, ikupita patsogolo, ingayambitse kupanga mipata yolimba m'minofu, m'mapapo, m'mero, m'maso, komanso mumtima. Izi zitha kusokoneza magwiridwe antchito a ziwalo izi. Izi zitha kubweretsa kulumala kwanthawi yayitali, kosatha, ndipo nthawi zina, ngakhale imfa.

Kodi chifukwa chachikulu cha NSF ndi chiyani?

NSF mwina imayamba chifukwa chogwiritsa ntchito mankhwala osiyanitsa omwe atchulidwa pamwambapa (ma GBCA)`. Mankhwalawa otchedwa gadolinium amagwiritsidwa ntchito kufotokoza zithunzi mu `(MRI)` scans. Sizikudziwikabe momwe gadolinium imayambitsira NSF. Komabe, n'zoonekeratu kuti pali mgwirizano pakati pa matenda a impso ndi `(GBCAs)`. Zawonetsedwanso kuti chiopsezo chimawonjezeka ngati kuchuluka kwa gadolinium komwe kumaperekedwa m'thupi kuli kokwera, kapena ngati mitundu ina ya `(GBCAs)` ikugwiritsidwa ntchito.

NSF imapezeka kwambiri mwa anthu omwe ali ndi matenda a impso osatha (CKD) ndi omwe amamwa dialysis chifukwa cha kulephera kwa impso.

Koma kumbukirani, palibe milandu yatsopano ya NSF yomwe yanenedwapo m'zaka pafupifupi 15!

Izi zili choncho chifukwa chakuti ma GBCA omwe alipo pano ndi okhazikika komanso osaopsa kwenikweni. Komanso, kugwiritsa ntchito gadolinium kwakhala koyenera kwa anthu omwe ali ndi matenda a impso okha. Ngakhale bungwe la FDA limalimbikitsa kuti anthu omwe ali ndi matenda a impso kapena mavuto a impso asagwiritse ntchito ma GBCA akale.

Ndani amene ali ndi mwayi waukulu wopeza izi? (Zinthu Zoopsa)

Chinthu chachikulu chomwe chingayambitse matenda a NSF ndi matenda a impso kapena kulephera kugwira ntchito bwino kwa impso. Izi zikuphatikizapo kuchitidwa opaleshoni ya impso kale, kusamutsidwa kwa impso, kapena kukhala ndi impso imodzi yokha. Komanso, ngati munthu amene ali ndi matenda a impso ali ndi matenda ena, monga mavuto okhudza magazi kapena matenda, chiopsezo cha matenda a NSF chikhoza kukhala chachikulu pang'ono.

Komabe, madokotala tsopano akuzindikira bwino za kuopsa komwe GBCA zakale zingayambitse mwa anthu omwe ali ndi vuto la impso. Chifukwa chake, ndi njira zotetezeka zomwe zilipo masiku ano, chiopsezo chanu chotenga matendawa ndi chochepa kwambiri.

Kodi mavuto omwe angakhalepo chifukwa cha NSF ndi ati?

Mavuto a NSF akhoza kukhala aakulu kwambiri ndipo nthawi zina amapha. Chizindikiro choyamba ndi kukhuthala kwa khungu. Komabe, pamene vutoli likuipiraipira, kuuma kumeneku kungakhudzenso ziwalo ndi minofu mkati mwa thupi. Mwachitsanzo, minofu ndi mafupa anu akhoza kukhala olimba kwambiri moti simungathe kuwasuntha, zomwe zimapangitsa kuti zikhale zovuta kuyenda. Ngati NSF ikhudza mapapo kapena mtima, ingayambitse kupuma movutikira kapena kusokoneza mphamvu ya mtima yopompa magazi.

Kodi matendawa amapezeka bwanji molondola? (Kuzindikira)

Njira yokhayo yodziwira ngati muli ndi NSF ndikuchitidwa biopsy ya khungu. Izi zimaphatikizapo dokotala kutenga chitsanzo cha khungu lanu ndikutumiza ku labu kuti akachiwunike. Komabe, dokotala amalamula mayesowa pokhapokha ngati, atatenga mbiri yanu yachipatala ndikuyesa thupi, akukayikira kuti mwina muli ndi NSF.

Kodi mankhwala a NSF ndi ati?

Ndipotu, pakadali pano palibe mankhwala enieni omwe amavomerezedwa a NSF. Popeza matendawa ndi osowa kwambiri, kafukufuku wa mankhwala ndi wochepa. Komabe, pali mankhwala ochepa omwe anenedwa kuti amapereka mpumulo kwa odwala ena a NSF:

• Pambuyo pa MRI, dialysis imatha kuchotsa gadolinium m'thupi. Izi zitha kukhala zothandiza kwa anthu omwe ali ndi matenda a impso osatha. Komabe, palibe umboni woti izi zitha kuletsa kukula kwa NSF.
• Kuchita masewera olimbitsa thupi kungathandize kusunga kusinthasintha ndi kuyenda kwa mafupa.
• Kuika impso ndi njira yomwe odwala ena a NSF angaganizire.

Ngati muli ndi matenda a impso, ndi bwino kupewa kukhudzana ndi gadolinium. Komabe, nthawi zina gadolinium ingakhale yofunikira kuti mupeze zithunzi zabwino kwambiri kuchokera ku MRI. Pazochitika zotere, madokotala ayenera kuyeza ubwino wa MRI poyerekeza ndi zoopsa za kukhudzana ndi gadolinium. Ngati muli ndi mavuto a impso ndipo dokotala wanu akulamula kuti MRI ikhale ndi utoto, onetsetsani kuti mwafunsa dokotala wanu ngati muli pachiwopsezo cha matenda a NSF.

Kodi pali njira zopewera NSF? (Kupewa)

Njira yabwino yopewera matenda a NSF ndikupewa kugwiritsa ntchito ma GBCA akale mwa anthu omwe ali ndi matenda a impso. Ma GBCA atsopano ndi otetezeka komanso osakhala oopsa kwa odwala impso.

Bungwe la FDA limalimbikitsa kuti anthu omwe ali ndi matenda ena a impso asagwiritse ntchito utoto wokhala ndi gadolinium pokhapokha ngati palibe njira ina.

Kwa anthu omwe ali ndi vuto la impso, sizikuwoneka kuti pali chiopsezo chilichonse chogwiritsa ntchito ma GBCA.

Kodi chiŵerengero cha imfa chifukwa cha NSF ndi chotani?

Isanafike chaka cha 2019, FDA inali itanena za milandu 3,094 ya NSF ndi imfa 742 zokhudzana nazo. Komabe, monga tanenera kale, palibe milandu yatsopano yomwe yanenedwapo m'zaka zoposa 10. Chifukwa chachikulu cha izi ndichakuti FDA ndi azachipatala akudziwa za zotsatira za GBCA pa odwala impso.

Kodi ndi liti pamene tiyenera kufunsa uphungu kwa dokotala?

Ngati muli ndi matenda a impso ndipo mukukumana ndi zizindikiro zotsatirazi, pitani kwa dokotala nthawi yomweyo chifukwa zikhoza kukhala chizindikiro cha NSF:

• Kulimbitsa kapena kukhuthala khungu.
• Khungu loyabwa kapena lotupa.
• Madontho ofiira kapena akuda pakhungu.

Ndi njira zodzitetezera zomwe zilipo panopa, mwayi woti mudzipeze ndi NSF ndi wochepa kwambiri. Komabe, ngati muli ndi matenda a impso ndipo mukufunika kuchitidwa MRI, lankhulani ndi dokotala wanu za NSF ndi zoopsa zomwe zingakuchitikireni. Ngakhale kuti ma GBCA atsopano si oopsa kwambiri ndipo akuwoneka kuti ndi otetezeka, nthawi zonse ndi bwino kugawana mbiri yanu yaumoyo ndi dokotala wanu ndikukambirana zoopsa zake.

Uthenga Wopita Nawo Kunyumba

Chabwino, tsopano mwamvetsetsa bwino zomwe takhala tikukambirana, NSF. Tiyeni tikambiranenso zinthu zofunika kwambiri:

• NSF ndi matenda osowa kwambiri, makamaka kwa anthu omwe ali ndi matenda a impso, ndipo amatha kuyambitsidwa ndi mankhwala ena akale osiyanitsa zithunzi za MRI.
• Palibe milandu yatsopano ya NSF yomwe yanenedwa pano. Izi zikuchitika chifukwa chogwiritsa ntchito mankhwala atsopano otetezeka komanso chidziwitso cha madokotala.
• Zizindikiro zazikulu ndi kukhuthala kwa khungu, kulimba, kuyabwa, ndi mavuto a mafupa.
• Ngati muli ndi matenda a impso, onetsetsani kuti mwalankhula ndi dokotala wanu za utoto womwe mumagwiritsa ntchito komanso chiopsezo cha NSF musanachite MRI.
• Palibe choopa, chifukwa ndi njira zomwe zilipo panopa, chiopsezochi n'chochepa kwambiri. Komabe, nthawi zonse ndikofunikira kudziwa.

Kusamalira thanzi lanu ndiye chinthu chofunika kwambiri. Ngati muli ndi mafunso kapena nkhawa, musazengereze kufunafuna upangiri wa dokotala.

Nephrogenic systemic fibrosis, matenda a impso, MRI scan, gadolinium, matenda a pakhungu, GBCAs, matenda osowa