Ndikumvetsa mantha, nkhawa, ndi kusatsimikizika komwe mumamva dokotala wanu akakuuzani kapena wokondedwa wanu kuti muli ndi khansa. Nthawi yomweyo, dokotala wanu akakuuzani za chithandizo chotchedwa "R-CHOP," mwina mumakhala ndi mafunso ambiri omwe akubwera m'maganizo mwanu, monga, "Ndi chiyani? Chimagwira ntchito bwanji?" Musadandaule. Lero, tikambirana za R-CHOP, chomwe imachita, komanso momwe mungathanirane nayo m'njira yosavuta yomwe mungamvetse.
Mwachidule, kodi R-CHOP ndi chiyani?
R-CHOP ndi mankhwala osakaniza asanu omwe amapha maselo a khansa . Ndi mankhwala othandiza kwambiri pa mtundu wa khansa wotchedwa non-Hodgkin lymphoma . Chilembo chilichonse m'dzina lake chimatanthauza mankhwala omwe amagwiritsidwa ntchito pochiza matendawa.
| Kalata | Mankhwala ndi ntchito yake |
|---|---|
| R | Rituximab: Iyi ndi njira yochizira matenda yomwe cholinga chake ndi kuthandiza. Makamaka, mankhwalawa amamangiriridwa ku puloteni yapadera pamwamba pa maselo a khansa. Izi zimathandiza kuti chitetezo cha mthupi lathu chizindikire mosavuta ndikuwononga maselo a khansa. |
| C | Cyclophosphamide: Iyi ndi mankhwala a chemotherapy. Mankhwala a chemotherapy amagwira ntchito powononga maselo omwe amagawikana mofulumira, monga maselo a khansa. |
| H | Doxorubicin hydrochloride (Hydroxydaunomycin): Iyi ndi mankhwala a chemotherapy. |
| O | Vincristine sulfate (Oncovin): Iyi ndi mankhwala ena a chemotherapy. |
| P | Prednisone: Uwu ndi mtundu wa steroid (corticosteroid). Umaphanso maselo a khansa. Umathandizanso kuchepetsa ziwengo zomwe zingachitike ndi mankhwala ena a R-CHOP. |
Monga mukuonera, izi zikuphatikizapo mankhwala a chemotherapy komanso mankhwala olimbana ndi chitetezo chamthupi (Rituximab). Ndicho chifukwa chake madokotala nthawi zina amatcha chithandizochi kuti "immuno-chemotherapy."
Kodi chithandizo cha R-CHOP chimagwiritsidwa ntchito pa mitundu iti ya khansa?
Chithandizochi chimaperekedwa makamaka pa mtundu wa khansa wotchedwa non-Hodgkin lymphoma . Chimagwiranso ntchito kwambiri pa mtundu wofala kwambiri wa B-cell lymphoma (DLBCL) . Kuphatikiza apo, R-CHOP imagwiritsidwanso ntchito pa mitundu iyi ya khansa :
- Matenda a follicular lymphoma opita patsogolo
- Mantle cell lymphoma
- Waldenstrom macroglobulinemia
Nthawi zina, dokotala wanu angasankhe kupereka R-CHOP pamodzi ndi mankhwala a mitundu ina ya khansa.
Kodi chithandizochi chimagwira ntchito bwanji?
Chithandizo cha R-CHOP chimaperekedwa mu "ma cycles." Nthawi zambiri cycle iliyonse imatenga milungu itatu (masiku 21). Pali magawo awiri a cycle iyi:
1. Masiku a chithandizo: Masiku omwe mumapatsidwa mankhwala.
2. Masiku opumula: Masiku oti thupi lanu lichiritse ndikuchira lisanafike nthawi yotsatira.
Masiku a chithandizo
Mankhwalawa angaperekedwe kwa masiku asanu. Prednisone ( steroid ) ndi piritsi lomwe mumameza. Mankhwala ena anayi amaperekedwa ngati madzi amchere mumtsempha (intravenous infusion - IV). Izi zidzakukakamizani kupita kuchipatala kapena ku chipatala. Kumeneko mudzakhala pampando pamene makina akulowetsa mankhwalawo pang'onopang'ono mumtsempha m'thupi lanu. Mtsempha uwu ukhoza kukhala m'dzanja lanu, m'dzanja lanu, kapena pachifuwa. Ngati chithandizocho chikuperekedwa kudzera pachifuwa, chipangizo chaching'ono chotchedwa `port-a-cath` (chemo port) chikhoza kuikidwa pansi pa khungu.
Pa tsiku loyamba la chithandizo, mudzapatsidwa mankhwala oletsa nseru. Mudzapatsidwanso mankhwala oletsa ziwengo. RituximabNdizachilendo kumva chizungulire pang'ono komanso kutentha pamene mankhwala aperekedwa. Ndicho chifukwa chake mankhwalawa amaperekedwa mosamala kwambiri poyamba. Koma palibe chodetsa nkhawa, chifukwa mudzapatsidwa mankhwala ofunikira pasadakhale kuti mupewe ziwengo zazikulu.
Masiku opumula
Mu nthawi yachizolowezi, mudzakhala ndi masiku pafupifupi 16 opuma mutatha kulandira chithandizo. Thupi limamva kutopa kwambiri pamene chithandizo cha R-CHOP chikuwononga maselo a khansa. Choncho ndi zachilendo kumva kutopa kwambiri masiku amenewa. Panthawiyi, ndi bwino kupempha thandizo kwa achibale ndi abwenzi pa ntchito za tsiku ndi tsiku.
Pa masiku opumula awa, ngati mukumva kuti muli ndi mphamvu, dokotala akulangizani kuti muchite masewera olimbitsa thupi opepuka, monga kuyenda. Ndikofunikanso kumwa madzi ambiri ndikudya zakudya zopatsa thanzi .
Kodi zoopsa ndi zotsatirapo zake ndi ziti?
Monga mankhwala ena aliwonse, R-CHOP ingayambitse zotsatirapo zoyipa. Koma kumbukirani, dokotala wanu adzakupatsani mankhwala omwe mukufunikira kuti mupewe kapena kuthana ndi zotsatirapo zoyipa zambirizi. Si aliyense amene amalandira zotsatirapo zoyipa zonsezi. Zimasiyana malinga ndi munthu. Tiyeni tiwone zina mwa zotsatirapo zoyipa zomwe zimafala kwambiri.
| Zotsatira zoyipa zofala | Zoyenera kudziwa ndi zomwe mungachite |
|---|---|
| Mkodzo wofiira/pinki | Doxorubicin ndi yofiira. Mkodzo wanu ukhoza kukhala wofiira/wapinki kwa maola 48 mutalandira chithandizo. Izi sizachilendo, musadandaule. |
| Kusanza ndi kusanza | Ngakhale mutamwa mankhwala a nseru, mutha kumvabe nseru pang'ono. M'malo modya zakudya zazikulu, zonenepa, komanso zokometsera, idyani zakudya zazing'ono, pafupipafupi. |
| Kutaya tsitsi | Izi zimachitika kawirikawiri ndi mankhwala a chemotherapy. Tsitsi limatha kutayika mkati mwa milungu itatu kuchokera pamene munthu wapatsidwa mlingo woyamba. Komabe, tsitsi limakulanso pambuyo poti chithandizo chatha. |
| Kuzizira ndi malungo | Mankhwala a chemotherapy angathandize kuchepetsa kuchuluka kwa maselo oyera m'magazi mwanu, zomwe zimawonjezera chiopsezo chanu chotenga matenda. Mudzapatsidwa jakisoni wotchedwa G-CSF, womwe umathandiza maselo oyera m'magazi mwanu kukula. Komabe, ngati mukuyamba kutentha thupi, uzani dokotala wanu nthawi yomweyo. |
| Kutopa kwambiri (Kutopa) | Chithandizo chingayambitse kuchepa kwa maselo ofiira a magazi, zomwe zimayambitsa kuchepa kwa magazi m'thupi. Ngati mukumva kutopa, pumulani. Pemphani thandizo pa ntchito za tsiku ndi tsiku. |
| Kutupa/kutuluka magazi mosavuta | Vutoli lingachitike chifukwa cha kuchepa kwa ma platelet. Samalani kuti musavulale. Uzani dokotala wanu ngati muwona mabala ambiri m'thupi lanu. |
| Kusanza/kumva kuwawa m'miyendo | Izi zimatchedwa peripheral neuropathy. Ngati mukumva kupweteka kapena kutentha m'manja kapena m'mapazi anu, uzani dokotala wanu. |
Kumbukirani, kutentha thupi kungakhale chizindikiro cha matenda oopsa. Ngati kutentha thupi kwanu kuli pamwamba pa 38°C, imbani dokotala wanu kapena chipatala nthawi yomweyo.
Kuwonjezera pa izi, mungakhalenso ndi zilonda pakamwa, ziphuphu pakhungu, mutu, kudzimbidwa kapena kutsegula m'mimba, kupweteka pachifuwa, kusowa tulo, komanso kusintha kwa malingaliro. Lankhulani ndi dokotala wanu za chilichonse mwa izi.
Kodi ndiyenera kuyimbira dokotala liti?
Uzani dokotala wanu nthawi yomweyo ngati muyamba zizindikiro zatsopano kapena ngati zizindikiro zanu zikuipiraipira panthawi ya chithandizo, makamaka ngati mukuyamba kutentha thupi.
Ngati pachitika zadzidzidzi monga kupuma movutikira kapena kupweteka pachifuwa mwadzidzidzi, pitani ku Dipatimenti Yothandiza Padzidzidzi (ETU) ya chipatala chapafupi nthawi yomweyo.
Kodi ndingathandize bwanji kuti nthawi imeneyi ya chithandizo ikhale yosavuta kwa ine?
Nkhondo iyi si yoti muyenera kumenya nokha. Pali zinthu zingapo zomwe mungachite kuti nthawi ino ikhale yosavuta.
- Dziwani izi: Lankhulani ndi dokotala wanu za chithandizo chanu ndi zomwe mungayembekezere. Musaope kufunsa mafunso.
- Pemphani thandizo: Pemphani thandizo kwa abale ndi abwenzi pa ntchito zapakhomo, kuphika chakudya, ndi kupita kuchipatala.
- Idyani ndi kumwa bwino: Idyani zakudya zopatsa thanzi. Imwani madzi ndi zakumwa zambiri.
- Pezani chithandizo: Funsani dokotala wanu za magulu othandizira omwe ena omwe akulandira chithandizo chofanana ndi chanu akukumana ndi khansa. Ndi mphamvu yayikulu kukhala ndi munthu woti mugawane naye zomwe mwakumana nazo.
Masabata oyamba a chithandizo cha R-CHOP akhoza kukhala nthawi yovuta. Masiku a mankhwala amatha kukhala aatali ndipo zotsatira zake zimakhala zovuta kuthana nazo. Koma kwa anthu ambiri, zotsatira za R-CHOP ndizofunika kwambiri. Kuphatikiza kwa mankhwala atatuwa (omwe amaperekedwa, chemotherapy, ndi steroids) kumagwira ntchito bwino kwambiri popha maselo a khansa. Kutengera ndi matenda anu, izi zingathandize kuti khansayo ichepe kwathunthu.
Uthenga Wopita Nawo Kunyumba
- R-CHOP ndi mankhwala othandiza kwambiri ophatikiza mankhwala 5 omwe amagwiritsidwa ntchito pochiza khansa monga non-Hodgkin lymphoma.
- Chithandizo chimaperekedwa mu "ma cycles." Panthawiyi, nthawi zambiri zimakhala ndi zotsatirapo zoyipa monga kutopa, nseru, ndi kutaya tsitsi.
- Zotsatirapo zambiri zimatha kuthetsedwa. Nthawi zonse lankhulani ndi gulu lanu lachipatala za izo.
- Ngati mukuyamba kutentha thupi panthawi ya chithandizo, ganizirani ngati vuto ladzidzidzi ndipo funsani upangiri wa dokotala nthawi yomweyo.
- Simuyenera kudutsa ulendowu nokha. Pezani thandizo kuchokera kwa abale anu, anzanu, ndi gulu lanu lachipatala. Ndinu olimba mtima. Mutha kuchita izi.
R-CHOP, khansa, Non-Hodgkin lymphoma, chemotherapy, chithandizo cholunjika, chithandizo cha khansa, zotsatirapo zake
💬 Comments (0)
Palibe ndemanga zomwe zatumizidwa pano. Onjezani ndemanga yanu pano koyamba.
Onjezani ndemanga yanu