Kodi inuyo kapena munthu wina amene mumamudziwa adapatsidwa mankhwala ndi dokotala chifukwa cha matenda monga kuvutika maganizo? Ngati ndi choncho, mwina munamvapo dzina lakuti SNRI. Ndizachilendo kuti mafunso ambiri abwere m'maganizo mukamva dzinali. "Kodi ma SNRI ndi chiyani? Amagwira ntchito bwanji kwenikweni? Kodi pali zotsatirapo zina?" Mwina muli ndi mafunso ngati awa. Musadandaule, chabwino, tiyeni tikambirane zonsezi m'njira yosavuta komanso yochezeka lero.
Choyamba tiyeni tiwone, kodi ma SNRI amenewa ndi chiyani?
Mwachidule, ma SNRI (Serotonin ndi Norepinephrine Reuptake Inhibitors) ndi gulu la mankhwala omwe amagwiritsidwa ntchito poletsa zizindikiro za matenda amisala monga kuvutika maganizo. Komabe, madokotala amapereka mankhwalawa pa matenda ena ambiri, osati kuvutika maganizo kokha.
Ku Sri Lanka, madokotala amalemba mankhwala angapo omwe ali mgululi. Mwachitsanzo, mankhwala monga Venlafaxine, Duloxetine, ndi Desvenlafaxine ali mgululi. Komabe , dokotala wanu yekha ndi amene angasankhe mankhwala oyenera kwa inu komanso mlingo wake.
Kodi mankhwalawa amagwira ntchito bwanji m'thupi?
Kuti timvetse izi, choyamba tiyenera kudziwa pang'ono za ubongo wathu. Ubongo wathu uli ndi amithenga apadera otchedwa neurotransmitters , monga a postmen omwe amanyamula mauthenga pakati pa ziwalo zosiyanasiyana za thupi lathu.
Pakati pa izi , Serotonin ndi Norepinephrine ndi awiri mwa amithenga akuluakulu omwe amalamulira zinthu zambiri zofunika, monga momwe timamvera, kugona, kukumbukira, ndi kusamala.
Mu matenda monga kuvutika maganizo, ntchito ya amithengawa imachepa. Izi zikutanthauza kuti, amalowanso mwachangu m'maselo amitsempha akamaliza kupereka uthenga (izi zimatchedwa reuptake). Kenako mphamvu yawo mu ubongo imachepa.
Ma SNRI amagwira ntchito poletsa kubwezeretsedwa kwa serotonin ndi norepinephrine. Izi zikutanthauza kuti ma messengers awiriwa amakhalabe akugwira ntchito muubongo kwa nthawi yayitali. Zotsatira zake, malingaliro athu amakula ndipo zizindikiro za kuvutika maganizo zimayamba kuchepa pang'onopang'ono.
Ndiye kusiyana kotani pakati pa SSRI ndi SNRI?
Mwina munamvapo za SSRIs. SSRIs (Selective Serotonin Reuptake Inhibitors) imangoyang'ana serotonin ya neurotransmitter, pomwe SNRIs imakhudza serotonin ndi norepinephrine.
Izi sizikutanthauza kuti ma SNRI ndi "abwino" kuposa ma SSRI. Anthu ena angaone kuti ma SSRI ndi othandiza kwambiri, pomwe ena angaone kuti ma SNRI ndi othandiza kwambiri. Dokotala wanu adzasankha chomwe chili chabwino kwa inu kutengera matenda anu, zizindikiro zanu, komanso momwe thupi lanu limayankhira.
Kodi mankhwala a SNRI amagwiritsidwa ntchito pa matenda ati?
Mankhwala amtundu uwu amagwiritsidwa ntchito pochiza matenda osiyanasiyana. Tiyeni tiwone zomwe zili.
| Matenda | Kufotokozera kosavuta |
|---|---|
| Matenda Ovutika Maganizo Akuluakulu | Chisoni cha nthawi yayitali komanso kutaya chidwi chomwe chimakhudza zochita za tsiku ndi tsiku. |
| Matenda Oda Nkhawa Omwe Amafala Kwambiri (GAD) | Kumva nkhawa yosatha pa zinthu za tsiku ndi tsiku popanda chifukwa chenicheni. |
| Fibromyalgia | Kupweteka kosatha m'thupi lonse, kutopa, ndi mavuto ogona. |
| Matenda a shuga a shuga | Ululu, monga kutupa ndi dzanzi, zomwe zimachitika chifukwa cha kuwonongeka kwa mitsempha chifukwa cha matenda a shuga. |
| Ululu Wosatha wa Minofu ndi Mafupa | Ululu wokhalitsa, monga kupweteka kwa msana. |
| Matenda a Nkhawa Pagulu | Mantha ndi nkhawa kwambiri pakakhala anthu. |
Kuphatikiza apo, kutengera zomwe dokotala wakumana nazo komanso malingaliro ake azachipatala, mankhwalawa angalimbikitsidwenso pa thukuta la usiku lomwe limabwera chifukwa cha kusamba, kupewa mutu waching'alang'ala, ndi matenda ena a nkhawa.
Kodi zotsatira zoyipa za mankhwalawa ndi ziti?
Monga mankhwala ena aliwonse, ma SNRI angayambitse anthu ena kukhala ndi zotsatirapo zazing'ono. Komabe, nthawi zambiri izi zimakhala zakanthawi kochepa . Zambiri mwa izi zimatha mkati mwa milungu ingapo yoyambirira pamene thupi lanu lizolowera mankhwalawo.
- Kusanza ndi kusanza
- Pakamwa pouma
- Kudzimbidwa
- Kutopa ndi kugona
- Chizungulire
- Thukuta kwambiri
- Mavuto okhudzana ndi kugonana (monga kuchepa kwa chilakolako)
Chofunika kwambiri ndichakuti ngati mukuda nkhawa ndi zotsatirapo zake, musanyalanyaze ndipo lankhulani ndi dokotala wanu. Iye akhoza kusintha mlingo wanu kapena kukupatsani mankhwala ena.
Zochitika zoopsa zomwe zimafuna chisamaliro chapadera
Ngakhale kuti mankhwala a SNRI ndi othandiza kwambiri, pali zinthu zina zomwe sizichitika kawirikawiri koma zomwe zingakhale zoopsa zomwe tiyenera kuzidziwa.
1. Kuwonjezeka kwa chiopsezo cha maganizo ofuna kudzipha
Kafukufuku wasonyeza kuti pakhoza kukhala kuwonjezeka kwa malingaliro ofuna kudzipha, makamaka kwa achinyamata osakwana zaka 25, pamene mankhwalawa ayamba kugwiritsidwa ntchito kapena pamene mlingo wa mankhwalawo wasinthidwa. Ngati inu kapena mwana wanu muli ndi maganizo otere pamene mukumwa mankhwalawa, musazengereze kulankhula ndi dokotala wanu nthawi yomweyo.
2. Matenda a Serotonin
Imeneyi ndi vuto losowa kwambiri, koma lomwe lingathe kupha munthu. Limachitika pamene serotonin m'thupi ikwera kwambiri. Chiwopsezochi chimakhala chachikulu makamaka ngati ma SNRI atengedwa pamodzi ndi mankhwala ena omwe amawonjezera serotonin (monga MAOIs). Chifukwa chake, ndikofunikira kwambiri kudziwitsa dokotala wanu za mankhwala onse omwe mukumwa, ngakhale mavitamini.
| Zizindikiro za Serotonin Syndrome | |
|---|---|
| Makhalidwe Abwino | Kusakhazikika, nseru, kutsegula m'mimba, maso otambasuka , kunjenjemera kwa minofu, thukuta, ndi kuzizira. |
| Zinthu zoopsa | Kusokonezeka, tachycardia, kuthamanga kwa magazi, kutentha thupi kwambiri, khunyu, kusazindikira. |
| Ngati muli ndi zizindikiro zoopsa izi, pitani ku chipatala chapafupi cha Emergency Department (ETU) nthawi yomweyo! | |
3. Kusiya mankhwala mwadzidzidzi
Ngati musiya kumwa SNRI kwa milungu yoposa 6, mutha kukhala ndi zizindikiro zina zosasangalatsa. Izi zimatchedwa Antidepressant Discontinuation Syndrome. Izi si "chizolowezi cha mankhwala osokoneza bongo." Izi ndi kuyesera kwa thupi kuzolowera mankhwalawo akasiya mwadzidzidzi. Zizindikiro zake zitha kuphatikizapo kupweteka thupi ngati malungo, mutu, nseru, chizungulire, komanso kumva phokoso.
Choncho , pazifukwa zilizonse, musasiye kumwa mankhwalawa mwadzidzidzi popanda kufunsa dokotala wanu. Ngati mukufuna kusiya kumwa mankhwalawo, chitani izi motsatira malangizo a dokotala wanu, pang'onopang'ono kuchepetsa mlingo.
Zimatenga nthawi yayitali bwanji kuti muwone zotsatira za mankhwala?
Funso limene anthu ambiri amafunsa ndi ili. Nthawi zambiri zimatenga milungu 6 mpaka 8 kuti zotsatira zonse za mankhwala a SNRI zimveke. Mudzayamba kumva bwino pakatha milungu iwiri kapena itatu yoyambirira. Chifukwa chake, ndikofunikira kukhala oleza mtima ndikugwiritsa ntchito mankhwalawo moyenera. Ngati simukumva kusiyana kulikonse pakatha nthawiyi, lankhulani ndi dokotala wanu za izi.
Uthenga Wopita Nawo Kunyumba
- Mankhwala a SNRI ndi gulu lothandiza kwambiri la mankhwala omwe amachiza matenda monga kuvutika maganizo, nkhawa, ndi ululu wosatha.
- Mankhwalawa amagwira ntchito poyesa kuchuluka kwa mankhwala otchedwa serotonin ndi norepinephrine mu ubongo.
- Zotsatira zoyipa zoyambirira nthawi zambiri zimakhala zakanthawi kochepa, koma ngati zikukuvutitsani, onetsetsani kuti mwadziwitsa dokotala wanu.
- Musasiye kumwa mankhwalawa mwadzidzidzi popanda upangiri wa dokotala.
- Dziwani zizindikiro zoopsa za serotonin syndrome (malungo aakulu, chisokonezo, khunyu). Ngati izi zitachitika, pitani kuchipatala chadzidzidzi (ETU) nthawi yomweyo.
- Zingatenge nthawi kuti mupeze mankhwala oyenera kwa inu. Choncho khalani oleza mtima ndipo pitirizani kulankhulana ndi dokotala wanu nthawi zonse. Dokotala wanu nthawi zonse amakhala wokonzeka kukuthandizani.
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