Nthawi zina dokotala angakuuzeni kuti pali kusintha pang'ono m'majini anu, kotchedwa 'Robertsonian Translocation'. Mutha kuchita mantha mukamva mawu awa. Ndizachibadwa kuganiza zinthu monga, 'Kodi uwu ndi matenda oopsa? Kodi udzakhala vuto kwa ana anga?' Koma musachite mantha. Ichi ndi chinthu chomwe anthu ambiri sadziwa, koma ndikofunikira kudziwa. Ichi ndi vuto losowa kwambiri, kutanthauza kuti pafupifupi, munthu m'modzi mwa anthu 900 ndi amene angakhale nalo. Lero, tikambirana za vutoli m'njira yosavuta, m'njira yomwe mungamvetse.
Mwachidule, kodi majini ndi ma chromosome ndi chiyani?
Tisanamvetse izi, tiyeni tione momwe matupi athu amapangidwira. Tangoganizani kuti matupi athu ndi laibulale yokhala ndi shelufu yayikulu ya mabuku. Buku lililonse mu laibulale iyi lili ndi malangizo omwe adatipanga.
Mabuku awa ndi omwe timawatcha ma chromosome mu zamankhwala. Awa ndi omwe amasunga chidziwitso chathu chonse cha majini - malangizo omwe amasankha chilichonse kuyambira mtundu wa tsitsi lathu, mtundu wa maso, kutalika, ndi mtundu wa khungu.
Kawirikawiri, munthu wathanzi amakhala ndi ma chromosome 46. Mwa awa, timapeza ma chromosome 23 kuchokera kwa amayi athu ndipo ena 23 kuchokera kwa abambo athu.
Ndiye kodi kusamuka kumeneku kwa Robertsonian kumachitika bwanji?
Mwa ma chromosome 46 omwe ali m'thupi lathu, ma chromosome 13, 14, 15, 21, ndi 22 ndi apadera pang'ono. Amatchedwa ma chromosome acrocentric . Ma chromosome awa ali ndi 'mkono' umodzi womwe ndi waufupi kwambiri. Chofunika kwambiri, mkono waufupi uwu ulibe chidziwitso cha majini chomwe chili chofunikira pakugwira ntchito kwa thupi lathu.
Tsopano, mu Robertsonian Translocation, chomwe chimachitika ndichakuti manja afupiafupi a ma chromosome awiri mwa asanu omwe ndatchula kale amathyoka, ndipo manja ataliatali a ma chromosome awiriwo amamatirana. Zili ngati kuthyola zidutswa ziwiri zazing'ono za timitengo tiwiri ndi kuzichotsa, kenako kumamatira zidutswa ziwiri zazikulu zotsalazo pamodzi. Kenako manja awiri ang'onoang'ono opanda ntchitowo amachoka.
Pamene ma chromosome awiri alumikizidwa pamodzi motere, chiwerengero chonse cha ma chromosome a munthuyo tsopano ndi 45, osati 46. Koma iye sadzakhala ndi mavuto aliwonse azaumoyo. Chifukwa zidutswa zochepa chabe zomwe zilibe majini ofunikira ndi zomwe zinatayika.
Kodi pali mitundu ya izi?
Inde, vutoli lingagawidwe m'magulu awiri akuluakulu. Mudzalimvetsa mosavuta poyang'ana tebulo ili.
| Mtundu | Kufotokozera |
|---|---|
| Kusamutsa Robertsonian Moyenera (Moyenera) | Anthu omwe ali ndi vutoli alibe zizindikiro kapena mavuto azaumoyo. Amakhala ndi moyo wautali komanso wathanzi. Nthawi zambiri, sadziwa ngakhale kuti ali nalo. Anthuwa amatchedwa 'onyamula' chifukwa alibe vutoli, koma amatha kulipereka kwa ana awo. |
| Kusamutsa Robertsonian Kosalinganika (Kosalinganika) | Apa ndi pomwe mavuto angabuke. Apa ndi pomwe mwana amalandira majini ambiri kapena ochepa kwambiri. Izi nthawi zambiri zimapezeka mwana akabadwa. Nthawi zina, ngakhale ma chromosome a makolo ali abwinobwino, vutoli limatha kuchitika mwana akukula m'mimba. Nthawi zambiri, m'modzi mwa makolo ndi amene amanyamula matendawa ndipo mwana amatha kukhala ndi vutoli. |
Kodi mwana amalandira bwanji vutoli?
Munthu wonyamula kachilombo ka Robertsonian Translocation akakhala ndi mwana ndi munthu wina, jiniyo imatha kutengedwa m'njira zitatu zazikulu. Tangoganizani kuti ndinu amene mumatenga kachilomboka.
1. Mwana wathanzi kwathunthu: Mwana wanu akhoza kulandira ma chromosome abwinobwino kuchokera kwa inu ndi mnzanu. Kenako mwanayo sadzakhala ndi mavuto a majini. Adzakhala wathanzi kwathunthu.
2. Mwanayo adzakhalanso wonyamula: Mwanayo, monga inu, akhoza kulandira chromosome yosinthidwa ndi ma chromosome abwinobwino. Kenako mwanayo sadzakhala ndi mavuto aliwonse azaumoyo. Koma nayenso adzakhala wonyamula ngati inu mtsogolo.
3. Mkhalidwe Wosalinganika: Apa ndi pamene mwana amalandira zinthu zina za majini. Mwachitsanzo, mwana angalandire chromosome yabwinobwino pamodzi ndi chromosome yowonjezera. Izi zingayambitse mwana kukhala ndi matenda enaake a majini, monga translocation Down syndrome kapena Patau syndrome . Komabe, mtundu ndi kuopsa kwa vutoli zimadalira ma chromosome enieni omwe alandiridwa.
Kodi pali zoopsa zina?
Mkazi amene ali ndi kachilombo ka Robertsonian translocation akhoza kukhala ndi chiopsezo chachikulu chotaya mimba kuposa chachibadwa. Komanso, amuna ena omwe ali ndi vutoli akhoza kukhala ndi vuto lochepa la umuna kapena kuchepa kwa mphamvu yopangira umuna.
Kodi mungazindikire bwanji vutoli?
Anthu ambiri sadziwa kuti ndi omwe ali ndi matendawa. Amangodziwa ngati apita padera mobwerezabwereza kapena ngati mwana wabadwa ndi vutoli. Kenako dokotala amalamula kuti apimidwe kuti adziwe.
Kuyesa kupeza izi n'kosavuta kwambiri. Ndi kuyesa magazi kosavuta. Magazi ochepa amatengedwa kuchokera kwa inu ndipo ma chromosome omwe ali m'maselo a magazi amawunikidwa pogwiritsa ntchito maikulosikopu. Kuyesa kumeneku kumatchedwa Karyotyping . Kenako kumatha kuwoneka bwino ngati muli ndi ma chromosome onse 46 motsatizana, kapena ngati muli ndi imodzi yocheperako (45), komanso ngati pali ma chromosome ena omwe amamatirana pamodzi.
Ngati mukudziwa kuti wina m'banja mwanu ali ndi vutoli, dokotala wanu angakulangizeni kuti inu ndi mnzanu muyesedwe mayesowa musanayambe kukhala ndi mwana.
Ndizachibadwa kuchita mantha komanso kuda nkhawa mukadziwa za vutoli. Koma chofunika kwambiri ndikupeza chidziwitso choyenera ndikupempha upangiri wofunikira kwa dokotala.
Uthenga Wopita Nawo Kunyumba
- Kusamutsa kwa Robertsonian si matenda oyenera kuwaopa. Anthu ambiri omwe ali ndi matendawa (omwe amanyamula matendawa) amakhala ndi thanzi labwino ndipo amakhala ndi moyo wabwinobwino.
- Chotsatira chachikulu cha izi ndi chiopsezo chopatsira jini kwa mwana. Komabe, ngakhale mutakhala ndi kachilomboka, muli ndi mwayi wobereka ana athanzi.
- Ngati muli ndi vuto la kutaya mimba kosalekeza, vuto la kutenga pakati, kapena mbiri ya banja lanu ya matenda obadwa nawo, ndi bwino kulankhula ndi dokotala wanu za kuyezetsa magazi monga karyotyping.
- Ngati muli ndi mafunso ena okhudza izi, musazengereze kufunsa dokotala wanu . Iye adzakupatsani chidziwitso chonse, upangiri, ndi maupangiri oti mukalandire upangiri wa majini ngati pakufunika kutero.
💬 Comments (0)
Palibe ndemanga zomwe zatumizidwa pano. Onjezani ndemanga yanu pano koyamba.
Onjezani ndemanga yanu