Ese nawe ufite ibibazo byo gusinzira? Reka tuvuge kuri Melatonin!

Ese hari igihe bikugora gusinzira nijoro? Ese uhora uhubuka amasaha menshi nyuma yo kuryama? Cyangwa se bikugora kubyuka mu gitondo? Ushobora kuba utazi ko hari ikintu gito mu mubiri wawe, imisemburo, bigira ingaruka kuri ibi bintu. Uyu munsi tugiye kuvuga kuri iyo misemburo itangaje yitwa melatonin .

Melatonin ni iki?

Muri make, melatonin ni imisemburo y'ingenzi cyane ifasha imibiri yacu gusinzira. Ikorwa n'agahu gato ko mu bwonko bwacu, pineal gland . Iyi melatonin, ikorwa n'imibiri yacu mu buryo busanzwe, yitwa melatonin y'umwimerere . Ni yo igenzura imikorere y'umubiri wacu mu gusinzira no mu gihe cyo kubyuka, bivuze ko twumva tunaniwe kandi tukabyuka mu bihe bitandukanye by'umunsi.

Tekereza nk'isaha karemano y'intabaza mu mubiri wacu. Mu ijoro, iduha ikimenyetso kivuga ngo "Sawa, iki ni cyo gihe cyo gusinzira."

Uretse iyi melatonin karemano, melatonin ikorwa mu buryo bw'ubukorano muri laboratwari ishobora no gufatwa nk'inyongera. Iyi yitwa melatonin yo hanze . Izi ziboneka mu buryo butandukanye, nk'ibinini na capsule.

Ni iki melatonin ikora mu by'ukuri?

Melatonine igenzura cyane cyane imikorere yacu ya circadian . Iyi ni imikorere yacu y'amasaha 24 yo gusinzira no kubyuka. Tekereza nk'isaha isanzwe y'umubiri wacu.

Melatonine si ikintu cy’ubumaji kigutera gusinzira ako kanya. Ariko ni impinduka ikomeye mu mikorere y’umubiri iba mu mibiri yacu buri munsi . Ni yo ifasha mu gutegura umubiri gusinzira.

Ingirabuzimafatizo yawe ya pineal irekura melatonine nyinshi iyo umwijima ubaye mwinshi. Nanone, umusaruro wa melatonine ugabanuka iyo uhuye n'urumuri. Muri make, urugero rwa melatonine mu maraso yawe rurazamuka iyo usinziriye nijoro, rukagabanuka ku manywa iyo hari urumuri.

Uko ijoro rirushaho kuba rinini, niko melatonine yawe irushaho gusohora. Niyo mpamvu bamwe baryama vuba kandi bakumva basinziriye kenshi mu gihe cy'itumba. Ibi biterwa nuko izuba riba rike kandi umwijima uba mwinshi mu gihe cy'itumba. Bityo umubiri urekura melatonine nyinshi mu buryo busanzwe.

Melatonin ikora ite?

Melatonin ni ubutumwa bw'imiti bubwira umubiri wawe buti "Sawa, ubu ni igihe cyo kuruhuka no kwitegura kuryama." Agahu ka pineal gland kawe gahita gasohora melatonin y'inyongera mu gihe kimwe buri munsi, akenshi ahagana ku mugoroba.

Iyi melatonin ikorerwa muri hypothalamus mu bwonko bwacu.Igira ingaruka ku turemangingo. Ibwira hypothalamus guhagarika gukora no kugabanya ibikorwa by'umunsi. Iyo yakiriye ubwo butumwa, hypothalamus igabanya ibintu igenzura, nk'ubushyuhe bw'umubiri, umuvuduko w'amaraso, n'amarangamutima , kugira ngo igutegurire gusinzira.

Melatonin kandi igira ingaruka ku maso yawe. Itegura retina zo mu maso yawe kuruhuka no kudakora cyane. Melatonin igabanya ubushobozi bwa retina bwo kumva urumuri. Ibi bigufasha kuruhuka no kumva udakomeye. Iyo urumuri rusanzwe rwiyongereye mu gitondo gikurikiyeho, retina zawe zihita zikora, bikagabanya irekurwa rya melatonin mu mubiri.

Ni izihe nyungu za Melatonin?

Melatonine igira uruhare runini mu gutuma uryama bihagije. Kugira ngo wumve unaniwe buri joro, umubiri wawe ukeneye kwibutswa ibinyabutabire bisanzwe. Gusinzira neza ni ingenzi ku buzima bwawe bwose, kuva ku musatsi wawe kugeza ku ngingo z'imbere, ubuzima bwawe bwo mu mutwe no mu byiyumvo, ndetse n'uruhu rwawe.

Dore ikindi kintu Melatonin ishobora gufasha:

• Melatonin ifasha abagore kugumana imihango yabo ihoraho .
• Melatonin ishobora kandi kurinda ubuzima bw'ubwonko bwawe no gukumira kwangirika kw'uturemangingo tw'ubwonko , ari na byo bitera indwara nka dementia (nk'indwara ya Alzheimer ) na Parkinson .
• Ubushakashatsi bumwe bwagaragaje ko abantu babazwe pineal gland basaza vuba kurusha abaturage muri rusange, bigatuma bamwe mu bahanga mu bya siyansi bemera ko melatonin karemano ishobora kugira ingaruka ku gusaza .

Wibuke ko akazi ka melatonin ari ukugenga imikorere y'ibitotsi n'ibikanguro byacu. Ariko si ibyo gusa, ahubwo inagira uruhare mu bindi bintu byinshi mu mubiri.

Ese urugero rusanzwe rwa melatonin rukwiye kuba rumeze rute?

Igipimo cya melatonin yawe karemano gishobora gutandukana bitewe n'imyaka yawe n'igitsina wahawe igihe wavukaga. Abagore muri rusange bafite igipimo cya melatonin kiri hejuru kurusha abagabo.

Ingano ya melatonine mu mubiri wawe itera impinduka mu buzima bwawe bwose.

• Abana bavutse ntibakora melatonin yabo bwite. Mbere yo kuvuka, bahabwa melatonin iva mu nyababyeyi . Nyuma yo kuvuka, bashobora kuyikura mu mashereka cyangwa mu mata. Abana bagira uruziga rwa melatonin hagati y'amezi 3-4.
• Urugero rwa Melatonin ruri hejuru cyane mu bana no mu rubyiruko iyo begereje ubwangavu. Nyuma y'ubwangavu, urugero rwa melatonin rugenda rugabanuka buhoro buhoro, rugera ku rwego ruhamye mu mpera z'ubwangavu. Urugero rukomeza kuba ruhamye kugeza ku myaka 40, nyuma y'aho rugabanuka mu buzima bwose.

Ushobora kutamenya urugero rwa melatonin yawe, nubwo waba udafite ibimenyetso cyangwa udakeneye ibizamini kugira ngo ubipime. Ariko niba ukorewe ikizamini cya melatonin, muganga wawe azakubwira niba urugero rwawe ruri mu rugero rusanzwe.

Ni ibihe bibazo bya melatonin?

Hari ibintu bibiri by'ingenzi bifitanye isano na melatonin: Hypomelatoninemia (urugero ruri hasi ugereranije n'urugero rusanzwe rwa melatonin) na Hypermelatoninemia (urugero ruri hejuru ugereranije n'urugero rusanzwe rwa melatonin).

Hypomelatoninemia - melatonine nkeya

Ibi bishobora kubaho iyo urugero rwa melatonine yawe yo mu ijoro ruri hasi ugereranije n'ibisanzwe. Cyangwa, bishobora kuba umubiri wawe urimo gukora melatonine nkeya ugereranyije n'uko byari byitezwe ku myaka yawe.

Hypomelatoninemia ishobora gutera indwara zo gusinzira mu buryo bwa circadian rhythm . Izi ndwara zo gusinzira zibangamira imikorere yawe isanzwe yo gusinzira no kubyuka. Zishobora kugira ingaruka kuri ibi bikurikira:

• Igihe ugiye gusinzira n'igihe ukangutse
• Mbega ukuntu usinziriye neza.
• Uko wumva umeze iyo uri maso n'uko ukora.

Tekereza nawe, hari abantu badashobora gusinzira nijoro, cyangwa bakabyuka kare mu gitondo ntibashobora kongera gusinzira. Cyangwa abantu bakora akazi k'ijoro bagorwa no gusinzira ku manywa. Ibi bintu bishobora kugira ingaruka ku mpinduka mu rugero rwa melatonine.

Hypermelatoninemia - kwiyongera kwa melatonine

Ibi bivuze ko ingano ya melatonine mu maraso yawe ari nyinshi cyane. Impamvu nyamukuru ibitera ni ugufata inyongera nyinshi za melatonine zikozwe mu buryo bwa sintetike. Bishobora kandi kubaho iyo pineal gland yawe ikora melatonine nyinshi (nubwo ibi biba gake cyane).

Kugira hypermelatoninemia bishobora kongera ibyago byo kurwara indwara zimwe na zimwe. Urugero:

• Anorexia nervosa (n'izindi ndwara zo kurya)
• Hypogonadotropic hypogonadism (ikibazo cya pituitary gland cyangwa hypothalamus gituma umubiri udakora estrogen cyangwa testosterone ihagije)
• Indwara y'intanga ngabo (PCOS)(Kuba hari imisemburo idahuye neza bishobora gutera imihango idahoraho ndetse no kuba nta bugumba)
• Indwara ya Rabson-Mendenhall (indwara idakunze kugaragara mu ngirabuzimafatizo itera ubudahangarwa bukomeye bwa insuline n'isukari nyinshi mu maraso)
• Kubura ubwinshi bw'ubwonko mu buryo butunguranye (ubushyuhe butunguranye, butunguranye no kubira ibyuya byinshi)

Ese ni byiza gufata melatonin hanze nk'inyongeramusaruro?

Izi nyongeramusaruro ntizigenzurwa n'ibigo nka FDA, bivuze ko nta buyobozi bukomeye ku bigize izo nyongeramusaruro, urugero cyangwa umutekano wazo. Abahanga mu bya siyansi baracyakora ubushakashatsi ku byiza bishobora guterwa na melatonin y’ubukorano.

Ni ngombwa kumenya ko inyongeramusaruro za melatonin atari "ikintu cy'igitangaza" kizakemura ibibazo byawe byo gusinzira. Ntabwo zemewe na FDA kuvura indwara iyo ari yo yose, kuvura ibimenyetso, cyangwa gutanga inyungu iyo ari yo yose ku buzima.

Ni byiza kugisha inama muganga mbere yo gutangira imiti mishya, cyane cyane niba ufata indi miti. Vugana na muganga wawe ku bibazo byawe byo gusinzira. Bashobora kugufasha kumenya icyabitera n'uburyo ushobora gusinzira neza kandi ukaruhuka.

Nubwo waba utabizi, melatonin ni igice cy'ingenzi cyane mu buzima bwawe bwa buri munsi. Ifasha umubiri wawe gutegura ibitotsi nijoro no kubyutsa mu gitondo. Niba urugero rwa melatonin rwawe rutari ku rugero rwiza kubera impamvu iyo ari yo yose, ushobora gutangira kugira ibimenyetso by'indwara yo gusinzira. Niba ufite ikibazo cyo gusinzira (no kubyuka), vugana na muganga.

Nubwo inyongeramusaruro za melatonine ziboneka ku giciro cya farumasi nta muganga wanditse, nta cyizere cy'uko zizagufasha. Mbere yo gutangira inyongeramusaruro nshya, ongera uganire na muganga. Bashobora kugufasha gufata ibyemezo byiza kuri wowe no ku buzima bwawe.

Amaherezo, ibintu byo kwibuka

Sawa, twavuze byinshi kuri melatonine. Muri make, dore ibintu bike ugomba kuzirikana:

• Melatonin ni imisemburo karemano ikorwa n'umubiri wacu idufasha gusinzira.
• Ibi bigenzura imikorere yacu yo gusinzira no kubyuka (Circadian rhythm). Bikorwa cyane iyo umwijima utangiye kwira, bikadutegurira gusinzira, kandi bike iyo urumuri rutangiye kudukangura.
• Melatonin ni ingenzi atari mu gusinzira gusa, ahubwo no mu bintu nk'imihango n'ubuzima bw'ubwonko.
• Iyo urugero rwa melatonine ruri hasi (Hypomelatoninemia), ibibazo byo gusinzira bishobora kubaho. Iyo ruri hejuru (Hypermelatoninemia), ibindi bibazo by'ubuzima bishobora kubaho.
• Inyongeramusaruro za Melatonine si "ikintu cy'igitangaza." Buri gihe banza uganire na muganga mbere yo kuzikoresha.
• Niba ufite ibibazo byo gusinzira bidashira, ni byiza gushaka inama kwa muganga kugira ngo bamenye impamvu.

Ndizera ko aya makuru wayasanze ari ingirakamaro. Gusinzira neza ni ingenzi kugira ngo umuntu abeho neza!

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