Reka twige ku binini bya Imatinib? Bigufashe mu kurwanya kanseri!

Ese wowe cyangwa umuntu uzi wigeze arwana na kanseri? Muri ibyo bihe, abaganga baduha imiti itandukanye, sibyo? Imatinib ni umuti wihariye ufasha mu kugenzura uturemangingo twa kanseri. Reka tuvuge kuri uyu muti mu buryo burambuye uyu munsi, si byo se?

Ni ubuhe bwoko bw'umuti Imatinib?

Muri make, Imatinib ni umuti ugezweho wibasira uturemangingo twa kanseri kandi ugafasha guhagarika gukura kwatwo. Kimwe n'icyuma gikoresha sniper, yibasira poroteyine runaka mu turemangingo twa kanseri mu gihe irinda uturemangingo twinshi dushoboka. Ibi bigabanya uturemangingo twa kanseri kwigabanya no gukwirakwira.

Irindi zina ry'uyu muti uri ku isoko ni Gleevec . Muganga wawe ashobora kandi kwita uyu muti kuri iri zina.

Ni ubuhe bwoko bw'indwara uyu muti ukoreshwa?

Uyu muti witwa Imatinib, ukoreshwa cyane cyane mu kuvura ubwoko bumwe na bumwe bwa kanseri y’amaraso , ari yo kanseri ikura mu maraso. Byongeye kandi, ni:

• Indwara za Myelodysplastic ni indwara ziterwa n'umusemburo w'amagufwa.
• Ku bundi bwoko bwa kanseri.
• Ikoreshwa kandi ku bwoko bwihariye bw'ibibyimba biba mu buryo bw'igogora (ni ukuvuga amara), byitwa GISTs (Gastrointestinal Stromal Tumors) .

Ariko ibuka ko abaganga bashobora gukoresha uyu muti ku zindi ndwara, bityo niba ufite ikibazo ku mpamvu wahawe uyu muti, ni byiza kubaza muganga wawe cyangwa umufarumasiye wawe.

Ni ibihe bintu ugomba kubwira muganga mbere yo gufata umuti?

Mbere yo gutangira gufata Imatinib, hari ibintu bike ugomba kubwira muganga wawe. Nutabimubwiye, bishobora kutagukwiriye, cyangwa bishobora guteza ibindi bibazo. Rero menya neza ko ubimubwiye:

• Niba ufite ibibazo byo kuva amaraso.
• Niba ufite ubwandu ubwo aribwo bwose ubu - cyane cyane ubwandu bwa virusi nka chickenpox na herpes.
• Niba ufite indwara y'umutima cyangwa umutima unaniwe.
• Niba ufite indwara y'impyiko.
• Niba ufite indwara y'umwijima.
• Niba ufite indwara y'ibihaha.
• Niba ufite ibibazo byo mu gifu.
• Niba warigeze kugira ikibazo cyo kugira ubwivumbure kuri Imatinib mu bihe byashize, cyangwa undi muti, ibiryo, irangi, cyangwa imiti irinda ubushyuhe.
• Niba utwite cyangwa ugerageza gutwita.
• Niba uri umubyeyi wonsa.

Ni ingenzi cyane ku mutekano wawe guha aya makuru muganga!

Ni gute wakoresha uyu muti neza?

Ni ingenzi cyane kumenya neza uburyo bwo gufata uyu muti. Ugomba gukurikiza neza icyo muganga avuze.

• Iki ginini kigomba gufatwa n'ikirahure kinini cy'amazi . Ntugafate iki ginini n'amazi make.
• Ni byiza kuyifata hamwe n'ibiryo. Ibi bishobora kugabanya ububabare mu gifu no kugira isesemi.
• Ntugafate uyu muti hamwe n'umutobe w'imbuto z'umuzabibu ku mpamvu iyo ari yo yose. Umutobe w'imbuto z'umuzabibu ushobora kubangamira imikorere y'uyu muti.
• Fata umuti neza neza nk'uko muganga wawe yabigutegetse, mu gihe gikwiye, mu rugero rukwiye. Ntukigere ufata ibirenze ibyo muganga akubwira, cyangwa ngo uwufate kenshi.
• Ntugahagarike gufata uyu muti mu buryo butunguranye utabanje kugirwa inama na muganga.

Hari abantu bagorwa no kumira ibinini, si byo se? Niba ufite icyo kibazo, vugana na muganga wawe, umufarumasiye, cyangwa inzobere mu by'ubuzima. Bashobora kugufasha muri ibyo. Hari uburyo bwo gushongesha ikinini mu mazi no kuginywa, ariko ibyo bigomba gukorwa gusa ukurikije inama za muganga.

Bite se niba uyu muti uhawe abana...?

Yego, mu bihe bimwe na bimwe byihariye, Imatinib ishobora guhabwa abana bafite umwaka umwe. Ariko ibyo bifatwaho umwanzuro n'umuganga w'abana. Hari ibintu bike ugomba kwitondera cyane iyo uyihaye abana. Kubwibyo, niba uha umwana uyu muti, ni ngombwa kuganira na muganga kuri wo no kumusobanurira byose.

Wakora iki iyo ufashe imiti myinshi cyane wibeshye?

Niba ibyo bibaye, ni ukuvuga ko niba utekereza ko wafashe ibirenze ibyo watekerezaga, ugomba guhita uhamagara ikigo gishinzwe kurwanya uburozi cyangwa icyumba cy’ubutabazi bw’ibanze cy’ibitaro biri hafi aho. Ntugapfushe ubusa. Uyu ni umuti wanditswe kuri wewe, ntukawusangire n’undi muntu uwo ari we wese.

Wakora iki iyo usibye gahunda yo gufata imiti?

Niba wibagiwe gufata dose ku bushake, uyifate ako kanya wibuka. Ariko, niba igihe cyo gufata dose ikurikira kigeze, rekeraho dose yabuze hanyuma ufate dose ikurikira ku gihe cyagenwe. Ntukigere ufata dose ebyiri kugira ngo wishyure dose wibagiwe. Kubikora bishobora kongera ingano y'umuti ufata.

Ni iyihe miti yindi ishobora kugira ingaruka kuri uyu muti?

Ibi ni ingenzi cyane . Imatinib ishobora kugira ingaruka ku yindi miti ufata. Ibi bivuze ko iyo uyifashe hamwe n'iyo miti, ingaruka za Imatinib zishobora guhinduka, cyangwa ingaruka z'indi miti zishobora guhinduka, cyangwa ingaruka mbi zishobora kwiyongera.

Kubwibyo, iyo ufata Imatinib, ugomba kubwira muganga wawe imiti yose ufata (wanditswe na muganga wawe, iyo uguze muri farumasi, imiti gakondo, ibikomoka ku bimera, vitamine). Ugomba kandi kubwira muganga wawe niba unywa itabi, unywa inzoga, cyangwa ukoresha indi miti.

Imatinib ishobora kugira ingaruka ku miti ikurikira:

• Imiti imwe n'imwe igabanya ubukana bwa virusi itera SIDA cyangwa SIDA
• Bosentan
• Cisapride
• Clarithromycin
• Cyclosporine
• Deksamethasoni
• Diltiazem
• Alkaloids za Ergot (urugero: dihydroergotamine, ergonovine, ergotamine, methylergonovine)
• Erythromycin
• Umutobe w'imbuto z'imizabibu cyangwa imbuto z'imizabibu - Nkuko byavuzwe mbere, ibi bigomba kwirindwa rwose.
• Imiti igabanya cholesterol (urugero: atorvastatin, lovastatin, simvastatin)
• Imiti ivura indwara zo mu mutwe, ihungabana, cyangwa indwara zo mu mutwe
• Imiti irwanya imiyoboro y'amaraso (urugero: ketoconazole, itraconazole)
• Imiti ivura indwara z'umutima zidakora neza (urugero: amiodarone, bepridil, dofetilide, encainide, flecainide, propafenone, quinidine)
• Imiti ivura indwara zo mu mutwe (urugero: carbamazepine, phenobarbital, phenytoin)
• Ibinini byo gusinzira
• NSAIDs (urugero: ibuprofen, naproxen)
• Pimozide
• Rifabutin
• Rifampine
• Sildenafil
• Sirolimus
• Igiti cy'umuti wa St. John
• Tacrolimus
• Inkingo
• Verapamil
• Warfarin - umuti ubuza amaraso kuvura

Uru rutonde ntabwo rurambuye. Kubwibyo , ni byiza kubwira muganga wawe imiti yose ufata. Cyane cyane vugana na muganga wawe mbere yo gufata imiti nka parasetamol, aspirine, ibuprofen, ketoprofen, na naproxen.

Ni ibihe bintu ugomba kwitondera mu gihe ufata imiti?

Muganga wawe azakurikirana ubuzima bwawe buri gihe mu gihe ufata Imatinib. Ibi bizaba birimo gupimwa amaraso buri gihe kugira ngo barebe uburyo umuti ugira ingaruka ku mubiri wawe ndetse niba hari ingaruka mbi ufite. Niba ugaragaje ibimenyetso bishya, ugomba kubimenyesha muganga wawe ako kanya.

Menya neza ingaruka zikomeye zishobora guterwa n'uruhu.

Uyu muti ushobora gutera ingaruka zikomeye ku ruhu ku bantu bamwe na bamwe. Ibi bishobora kubaho ibyumweru cyangwa amezi nyuma yo gutangira umuti. Niba ugize uduheri ku ruhu duterwa n'umuriro cyangwa indwara isa n'ibicurane, bwira muganga wawe ako kanya.Ibisebe bishobora kuba umutuku cyangwa umuhengeri, hanyuma bigahinduka udusebe n'uduheri. Cyangwa, ibisebe bitukura bishobora guherekezwa n'uturemangingo twa lymph twabyimbye ku maso, ku minwa, mu ijosi, cyangwa mu kwaha.

Irinde indwara zandura

Niba ufite ibimenyetso nk'umuriro, ubukonje, kuribwa mu muhogo, cyangwa ibicurane, ntukiyivure. Hamagara muganga wawe vuba kugira ngo akugire inama. Uyu muti ushobora kugabanya ubushobozi bw'umubiri wawe bwo kurwanya indwara. Gerageza rero kwirinda abantu barwaye uko bishoboka kose.

Ingaruka zo kuva amaraso

Uyu muti ushobora kongera ibyago byo kuva amaraso cyangwa gukomereka. Bwira muganga wawe niba ukunze kugira ibisebe, kuva amaraso mu mazuru, kuva amaraso mu ishinya mugihe woza amenyo, cyangwa andi maraso adasanzwe.

Gusinzira no kugira isereri

Uyu muti ushobora gutuma usinzirira cyangwa uzungera. Kubwibyo, kugeza igihe uzaba umenye neza uko uyu muti umeze, irinde gutwara imodoka, gukoresha imashini, cyangwa gukora ikintu icyo ari cyo cyose gisaba kwitonda.

Uyu muti ni uwuhe ku babyeyi batwite n'abonsa?

Iki ni ikintu cy'ingenzi cyane .

• Ntugatwite urimo gufata uyu muti kandi mu gihe cy'iminsi 14 nyuma yo guhagarika uyu muti.
• Niba umugore ateganya gutwita, cyangwa atekereza ko atwite, agomba kubimenyesha muganga we. Uyu muti ushobora guteza ingaruka mbi zikomeye ku mwana uri mu nda. Baza muganga wawe cyangwa umufarumasiye wawe amakuru arambuye.
• Ntugahe umwana wawe ibere mu gihe ufata uyu muti kandi mu gihe cy'ukwezi kumwe nyuma yo guhagarika uyu muti.

Ni izihe ngaruka mbi zishobora guterwa n'uyu muti?

Kimwe n'indi miti iyo ari yo yose, Imatinib ishobora gutera ingaruka mbi ku bantu bamwe. Si buri wese uzibona, ariko hari n'abazibona. Bimwe muri ibi ni ibintu ugomba kubwira muganga wawe ako kanya , mu gihe ibindi bitameze neza cyane kandi bizashira mu minsi mike. Ariko, niba bikomeje cyangwa bikakubangamira, ugomba kubimenyesha muganga wawe .

Ingaruka mbi ugomba guhita ubibwira muganga wawe:

• Ibimenyetso bya aleriji: uduheri ku ruhu, kuribwa cyangwa uduheri, kubyimba mu maso, iminwa, ururimi.
• Ibibazo byo guhumeka.
• Impinduka mu iyerekwa.
• Inkari zijimye.
• Kumva urwaye muri rusange cyangwa ibimenyetso bisa n'ibicurane.
• Intebe z'amabara yoroheje.
• Kubura ubushake bwo kurya.
• Kugabanuka kw'umubare w'amaraso: Uyu muti ushobora gutuma umubare w'uturemangingo tw'amaraso twera, uturemangingo dutukura, n'udupira duto tw'amaraso tugabanuka. Ibi bishobora kongera ibyago byo kwandura indwara no kuva amaraso.
• Ibisebe byo mu kanwa.
• Ibisebe, umuriro, n'uturemangingo tw'imitsi tubyimba.
• Uruhu rutukura, gushyuha, gukurura cyangwa gucika intege bishobora no kugaragara mu kanwa.
• Kubabara mu nda yo hejuru y'iburyo.
• Ibimenyetso by'uko hari plaquette nkeya cyangwa kuva amaraso: gukomereka, kugaragaraho utudomo dutukura ku ruhu, umukara, kwituma mu nda, amaraso mu nkari, kuva amaraso mu mazuru.
• Ibimenyetso by'uturemangingo dutukura tw'amaraso: intege nke zidasanzwe, umunaniro, gucika intege, no kubabara umutwe.
• Ibimenyetso by'ubwandu: umuriro cyangwa ubukonje, inkorora, kuribwa mu muhogo, kubabara cyangwa kugorwa no kunyara.
• Kubyimba amaguru cyangwa utubuto tw'amaguru.
• Guhura n'ingorane zo gusohora inkari cyangwa guhindura ingano y'inkari.
• Kuruka.
• Ibara ry'umuhondo ry'amaso cyangwa uruhu.

Ingaruka mbi ubusanzwe zidasaba kuvurwa na muganga (ariko zigomba kumenyeshwa muganga niba zikomeje cyangwa zibangamiye):

• Kugabanuka k'ubushake bwo kurya.
• Impiswi.
• Kubura ibitotsi (kubura ibitotsi).
• Umutwe.
• Kuribwa mu gituza.
• Kubabara ingingo.
• Kubabara imitsi cyangwa ububabare.
• Isesemi.
• Igifu kibabara.

Uru rutonde rushobora kuba rudakubiyemo ingaruka mbi zose zishobora kubaho. Niba ubonye ikintu kidasanzwe, baza muganga wawe. Ushobora kandi gutanga raporo ku kigo gishinzwe ibiribwa n'imiti (FDA) kuri 1-800-FDA-1088 (muri Sri Lanka, ushobora kubimenyesha ikigo gishinzwe kugenzura imiti binyuze kuri muganga wawe).

Uyu muti nawubika nte?

Uyu muti ugomba kubikwa ahantu abana batagera . Ibyo ni ingenzi cyane.

• Bika ibinini ku bushyuhe bw'icyumba, hagati ya dogere selisiyusi 15 na 30 (dogere selisiyusi 59 na 86 Fahrenheit).
• Irinde ubushuhe. Ibyo bivuze ko utagomba kuyibika ahantu hatose nko mu bwiherero.
• Komeza ufunze neza icupa.
• Ntugakoreshe imiti yarengeje igihe. Ijugunye.

Aka gatabo ni incamake gusa. Gashobora kuba kadafite amakuru yose. Niba ufite ibindi bibazo kuri uyu muti, vugana na muganga wawe, umufarumasiye, cyangwa inzobere mu by'ubuzima.

Ubutumwa bwo kujyana mu rugo:

Sawa, rero, ukurikije ibyo twavuze kuri Imatinib, hari ibintu bike ugomba kwibuka :

• Imatinib ni umuti wihariye ufasha guhagarika gukura kw'uturemangingo twa kanseri. Uwufate neza nk'uko muganga wawe abikubwiye, ku gihe gikwiye, ku rugero rukwiye.
• Ugomba gufata umutobe w'imbuto z'umuzabibu.
• Bwira muganga wawe indi miti yose ufata n'indwara zawe zose . Ibi ni ingenzi cyane cyane niba utwite, ugerageza gutwita, cyangwa wonsa.
• Uzakenera gupimwa amaraso buri gihe. Menya impinduka z'uruhu, ibimenyetso by'ubwandu, no kuva amaraso ku buryo budasanzwe. Nubona ikintu nk'icyo , bwira muganga wawe vuba.
• Twanavuze ku cyo wakora niba ufashe imiti myinshi cyangwa ubuze ifunguro, si byo? Wibuke ibyo bintu.
• Bika uyu muti ahantu hakonje kandi humutse kure y'abana.

Intambara yo kurwanya kanseri ntabwo yoroshye. Ariko hamwe n'ubuvuzi bugezweho nk'ubu, no gukurikiza amabwiriza ya muganga witonze, uzabona imbaraga nyinshi zo gutsinda uru rugamba. Uko ikibazo ufite cyaba kiri kose, ntutinye kuvugana na muganga. Ndakwifurije gukira vuba!

imatinib , gleevec, kanseri, kanseri y'amaraso, GIST, imiti, ingaruka mbi