Icyo ukeneye kumenya ku bijyanye no kuvura kanseri ya Vorinostat (Zolinza)…

Ese muganga wawe yaba yarakwandikiye Vorinostat cyangwa undi muntu wo mu muryango wawe? Kubera ko uyu ari umuti wihariye ukoreshwa mu kuvura kanseri, ushobora kuba ufite ibibazo, amatsiko, ndetse wenda n'ubwoba buto. Ibyo ni ibisanzwe. Ntugahangayike. Muri iyi nkuru, turaganira kuri uyu muti, icyo ukora, n'icyo ugomba kumenya.

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Ni ubuhe bwoko bw'umuti Vorinostat ari wo?

Muri make, Vorinostat ni umuti wa chimiotherapie . Ariko ntabwo ari nk'umuti wa kanseri dusanzwe tubona mu bitaro hamwe n'umunyu. Ni kapsule unywa.

Uyu muti ukoreshwa by'umwihariko mu kuvura ubwoko bwa kanseri igaragara mu ruhu yitwa cutaneous T-cell lymphoma (CTCL) . Ushobora kumvikana nk'aho bigoye, ariko ni ubwoko bwa kanseri ifata uruhu. Muganga wawe akunze kuguha uyu muti akoresheje izina rya Zolinza.

Ibintu ugomba kubwira muganga wawe mbere yo gutangira uyu muti

Mbere yo gutangira uyu muti, ni ngombwa cyane kuganira na muganga wawe ku buzima bwawe bwose. Ibi biterwa nuko hari indwara zimwe na zimwe zisaba kwitabwaho by'umwihariko mu gihe ukoresha uyu muti. By'umwihariko, menya neza ko wabibwiye muganga wawe niba ufite:

Niba urwaye diyabete
Niba ufite amateka yo kubyimba kw'amaraso
Niba ufite ibibazo ku bijyanye n'umutima utera utari mwiza
Niba ufite indwara y'umwijima
Niba ufata indi miti irinda cyangwa ivura kubyimba kw'amaraso (nka warfarin)
Niba waragize ikibazo cy'ubwivumbure kuri Vorinostat cyangwa undi muti, ibiryo, cyangwa irangi.
Niba urimo kugerageza gutwita cyangwa usanzwe utwite
Niba umubyeyi yonsa umwana we

Ni gute wakoresha umuti neza?

Uburyo ukoresha uyu muti ni ingenzi cyane. Nk'uko muganga yabivuze, kuwufata ku gihe gikwiye ni bwo buryo bwiza bwo kubona ibisubizo byiza.

Iyi ni kapsule igomba gufatwa n'ikirahure cy'amazi.
Ni ingenzi cyane gufata uyu muti hamwe n'ifunguro . Ibi bizagabanya ibyago byo kubabara mu gifu.
Ntuzigere uhekenya, usya cyangwa ufungura kapsule hanyuma unywe ifu iri imbere. Kapsule igomba kumira yose.
Ntukanywe ibirenze ibyo muganga akubwira, kandi ntugahagarike kugeza igihe agutegetse kubireka.

Bite ho nindamuka nkoresheje imiti irenze urugero?

Tekereza ko wafashe dose irenze iyagenwe ku bushake. Ibi nibibaho, ntugatinye ujye ku bitaro bikuru byita ku bibazo byihutirwa (ETU) by'ibitaro biri hafi yawe ako kanya . Bitabaye ibyo, ntugatinye.Hamagara Ikigo cy'Igihugu gishinzwe gutanga amakuru ku burozi mu bitaro by'igihugu bya Colombo kugira ngo ubagire inama.

Bite ho niba nibagiwe gufata umuti wanjye?

Wakora iki niba wibagiwe gufata umuti wawe? Fata dose yabuze ukimara kwibuka. Ariko, niba igihe cyo gufata dose ikurikira kigeze, rekeraho dose yabuze hanyuma ufate dose ikurikira ku gihe cyagenwe. Ntukigere ufata dose ebyiri icyarimwe (dose ebyiri).

Uyu ni umuti wagenewe wowe gusa. Ntugahe undi muntu uwo ari we wese uyu muti ku mpamvu iyo ari yo yose.

Indi miti ishobora kugira ingaruka kuri uyu muti

Vorinostat ishobora guteza ingaruka mbi iyo ifashwe hamwe n'indi miti imwe n'imwe. Kubwibyo, ni ngombwa cyane kubwira muganga wawe imiti yose ufata (harimo vitamine, imiti ikomoka ku bimera, n'imiti igabanya ububabare).

Imiti ikurikira ntigomba na rimwe gufatwa na Vorinostat:
* cisapride
* dronedarone
* pimozide
* thioridazine

Byongeye kandi, hari indi miti ishobora kugira ingaruka kuri uyu muti. Niba ufata uyu muti, menyesha muganga wawe:

Amwe mu moko ya antibiyotike: nka clarithromycin, erythromycin, levofloxacin, mefloquine.
Imiti ivura indwara zo mu mutwe ziterwa no kwiheba, guhangayika, cyangwa izindi ndwara zo mu mutwe.
Imiti ivura indwara z'umutima.
Imiti nka aside valproic (umuti uvura indwara zo mu mutwe ).
Imiti ibuza amaraso kuzura: nka warfarin, enoxaparin, heparin.
Ubundi buryo bwo kuvura kanseri: nka dasatinib, lapatinib.
Indi miti igira ingaruka ku muvuduko w'umutima (yongerera igihe QT itera).

Uru rutonde ntirwuzuye. Bwira muganga wawe imiti yose ufata, niba unywa itabi, cyangwa niba unywa inzoga.

Ingingo zihariye ugomba kwitondera mu gihe ufata umuti

Hari ibintu bike ugomba kwitondera cyane mu gihe ufata uyu muti.

Gupima amaraso: Ni ngombwa ko upima amaraso buri gihe nk'uko muganga wawe yabigutegetse mu gihe ufata uyu muti. Ibi bizagufasha kugenzura uburyo uyu muti ugira ingaruka ku mubiri wawe, cyane cyane urugero rwa potasiyumu na manyeziyumu ndetse n'uturemangingo tw'amaraso.
Nywa amazi menshi: Nywa amazi menshi umunsi wose. Ni ingenzi cyane kwirinda umwuma. Baza muganga wawe ingano y'amazi ugomba kunywa ku munsi.
Udukapu tw'imiti witonze:Niba kapsule y'umuti yamenetse cyangwa ifu iri imbere igasohoka, ntukore kuri iyo fu cyangwa ngo uyireke ikore ku maso yawe cyangwa ku ruhu rwawe. Niba igeze aho, oza ako kanya n'isabune n'amazi. Niba igeze mu maso yawe, oza neza n'amazi hanyuma uhamagare muganga ako kanya.
Gutwita no konsa: Iki ni ikibazo gihangayikishije cyane.
Niba uri umugore, irinde gutwita mu gihe ufata uyu muti kandi byibuze amezi 6 nyuma yo guhagarika uyu muti.
Niba uri umugabo, ntugasange umwana mu gihe ufata uyu muti kandi nibura amezi atatu nyuma yo guhagarika uyu muti.
Uyu muti ushobora guteza ingaruka zikomeye ku mwana uri mu nda. Baza muganga wawe amakuru arambuye kuri ibi.
Niba uri umubyeyi wonsa, ntukonse umwana wawe mu gihe ufata uyu muti kandi nibura icyumweru kimwe nyuma yo kuwuhagarika.
Uburumbuke: Uyu muti ushobora kugira ingaruka ku burumbuke bwawe. Niba ufite impungenge kuri ibi, banza uganire na muganga wawe mbere yo gutangira kuvurwa.

Ingaruka mbi zishobora guterwa n'imiti

Nk’uko bimeze ku muti uwo ari wo wose, Vorinostat ishobora gutera ingaruka mbi. Zimwe ni mbi cyane, izindi ni ntoya. Icy'ingenzi ni ukumenya ibi bimenyetso no kubimenyesha muganga wawe vuba bishoboka niba hari icyo uhuye na cyo.

Ubwoko bw'ingaruka mbi	Ibiranga
Ibimenyetso bikomeye bisaba koherezwa kwa muganga wawe cyangwa Ishami rishinzwe ibibazo byihutirwa (ETU) byihutirwa
Ubushobozi bwo kugira ubwivumbure	Uruhu rushyushye, kuribwa cyane, kubyimba mu maso, iminwa cyangwa ururimi.
Indwara zo guhumeka n'ibimenyetso by'indwara z'umutima	Guhumeka bigoranye, kubabara mu gatuza, umutima utera vuba cyangwa utari umeze neza.
Ibimenyetso by'amaraso apfutse	Ububabare, kubyimba, no gutukura ku kuguru (akenshi ukuguru kumwe).
Ibindi bimenyetso bikomeye	Isesemi, kuruka, umuriro, ubukonje, kubabara mu muhogo, kuva amaraso cyangwa gukomereka bidasanzwe, umunaniro ukabije, kugorwa no kugenda cyangwa kuvuga, kubyimba amaguru.
Ibimenyetso bisanzwe bigomba kumenyeshwa muganga mu gihe bikomeje cyangwa bibangamiye
Ibibazo by'igogora	Impiswi, impatwe, isesemi, kuruka, kubabara mu nda.
Izindi ngeso rusange	Impinduka mu buryohe, umunwa wumye, kuribwa umutwe, kubura ubushake bwo kurya, kubabara imitsi.

Ni gute wakwirinda imiti?

Gufunga imiti ahantu abana bato batagera cyangwa ngo bayibone .
Bika ahantu hari ubushyuhe bwinshi (hagati ya dogere selisiyusi 15 na 30). Ntukabibike ahantu hari ubushyuhe bwinshi, nko mu bwiherero.
Tara imiti yarengeje igihe utayikoresheje.

Ubutumwa bwo kujyana mu rugo

Vorinostat ni umuti ukoreshwa mu kuvura ubwoko bwa kanseri witwa CTCL. Buri gihe fata uyu muti nk'uko muganga wawe yabigutegetse.
Bwira muganga wawe indi miti yose ufata n'indwara zose ufite.
Umira umuti wose hamwe n'ibiryo. Ntukawuhekenye, ntuwusye cyangwa ngo uwufungure.
Ugomba kwitonda cyane ku bijyanye no gukoresha uyu muti mu gihe utwite, mu gihe wonsa, ndetse no mu gihe utwite umwana. Kurikiza amabwiriza ya muganga wawe.
Shaka ubufasha bwihuse kwa muganga niba ugize ingaruka mbi nko kugorwa no guhumeka, kubabara mu gatuza, cyangwa kuva amaraso mu buryo budasanzwe.
Niba ufite ikibazo cyangwa impungenge, ntutinye kuvugana na muganga wawe. Ni uburenganzira bwawe kubaza ibibazo bijyanye n'ubuzima bwawe.

Icyo ukeneye kumenya ku bijyanye no kuvura kanseri ya Vorinostat (Zolinza) (Vorinostat)