Kana iwe kana mumwe munhu waunoda akanyorerwa mushonga mutsva wekurapa kenza, zvakajairika kunzwa kutya uye kuda kuziva. Kunyanya kana ukanzwa zita rakaita seAcalabrutinib, ungangove uchishamisika kuti, "Mushonga uyu ndewerudzii? Chii chiri kuitika mauri ?" Usazvidya mwoyo. Ndizvo chaizvo zvatiri kutaura nezvazvo munyaya ino. Tichataura nezvemushonga uyu nenzira iri nyore yaunogona kunzwisisa.
Mushonga werudzii unonzi Acalabrutinib?
Muchidimbu, Acalabrutinib mushonga unoshandiswa kurapa mamwe marudzi egomarara, kunyanya leukemia nelymphoma. Munyika medu, mushonga uyu unowanikwa pasi pezita rekuti CALQUENCE.
Izvi hazvina kufanana nemishonga yechivanhu yegomarara. Izvi zvinoshanda se "kurapa kwakanangana." Kureva kuti, mushonga uyu unotarisa zvakananga puroteni chaiyo inobatsira masero egomarara kukura nekupararira. Kana puroteni iyi ikarega kushanda, kugona kwemasero egomarara kukura kunodzikira, kana kuti anofa zvachose. Nenzira iyi, mushonga uyu unobatsira kudzora gomarara.
Zvinhu zvekuudza chiremba wako usati watanga mushonga
Usati watanga kushandisa acalabrutinib, zvakakosha kupa chiremba wako tsananguro yakazara yehutano hwako. Iva nechokwadi chekuudza chiremba wako kana uine chimwe chezvirwere zvinotevera:
- Kana uine chirwere chekubuda ropa (semuenzaniso, matambudziko ekugwamba kweropa).
- Kana wakambovhiyiwa nguva pfupi yadarika kana kuti uri kuronga kuzovhiyiwa mune ramangwana.
- Kana uine chirwere chemwoyo , BP , kana kurova kwemoyo kusina kurongeka.
- Kana paine hutachiona huripo.
- Kana uine chirwere chechiropa .
- Kana uri kutora mishonga yekuderedza ropa kudzivirira kana kurapa kuumbwa kweropa.
- Kana uine allergies kune acalabrutinib kana chero imwe mishonga, chikafu, kana dhayi.
- Kana uine pamuviri , uchiedza kubata pamuviri , kana kuti uchiyamwisa .
Nekupa ruzivo urwu kuna chiremba wako nemazvo, achakwanisa kukurapa zvakachengeteka uye zvinobudirira.
Ndinofanira kushandisa mushonga uyu sei?
Zvakakosha kutevedzera mirairo chaiyo yekushandisa mushonga uyu.
- Medza kapusule iyi yese negirazi remvura .
- Usambopwanya, kupwanya, kana kutsenga kapisiyu iyi. Medza yese.
- Kana ukasangana nemigumisiro yakaipa, chiremba wako anogona kukukumbira kuti uchinje mushonga kana kuti urege kuutora kwenguva yakati. Usarega kutora mushonga kana kuchinja mushonga chero chikonzero chipi zvacho usina kurayirwa nachiremba wako.
- Usatore mushonga uyu nemuto wegrapefruit.
- Kana uri kutora mishonga yemudumbu (antacids kana H2-blockers), itore maawa maviri usati watora Acalabrutinib kana kuti wapedza.
Ko kana ndikatora mushonga wakawandisa netsaona?
Kana uchifunga kuti watora mushonga wakawanda kupfuura zvaunofunga, usavhunduka uye fonera National Poisons Information Centre paColombo National Hospital nekukasika. Neimwe nzira, enda kuEmergency Treatment Unit (ETU) yechipatara chiri pedyo.
Ko kana ndikarasikirwa nedosi remushonga?
Kana ukarasikirwa nedosi, itore nekukurumidza sezvaunoyeuka. Zvisinei, kana ikanonoka kupfuura maawa matatu , svetuka dosi yawakarasikirwa nayo. Tora dosi yako inotevera panguva yakatarwa. Usatore dosi mbiri panguva imwe chete.
Zvimwe zvinhu zvinogona kupindirana nemushonga uyu (Kudyidzana)
Acalabrutinib inogona kushanda pamwe chete nemimwe mishonga, mavhitamini, kana mishonga yemiti yaungave uchitora. Saka udza chiremba wako nezvemishonga yese, mavhitamini, uye zvekudya zvinovaka muviri zvauri kutora. Pazasi pane zvimwe zvezvinhu zvinogona kukonzera matambudziko.
| Chii chinogona kukonzera matambudziko? | Tsananguro nemienzaniso |
|---|---|
| Mishonga inoderedza acid mudumbu | Mishonga yakaita seCimetidine, Famotidine, Omeprazole, Lansoprazole. Mishonga inorwisa mabhakitiriya. |
| Mamwe maantibayotiki | Mishonga yakaita seClarithromycin neRifampin. |
| Mishonga inorwisa fungus | Mishonga yakaita seKetoconazole, Itraconazole, Fluconazole. |
| Mishonga yekurapa pfari | Mishonga yakaita seCarbamazepine nePhenytoin. |
| Zvigadzirwa zvemiti | Zvigadzirwa zvakaita seSt. John's Wort. |
| Chikafu nechinwiwa | Muto weGrapefruit. |
Migumisiro inogona kuitika kana uchitora mushonga
Kufanana nemushonga upi zvawo, Acalabrutinib inogona kukonzera migumisiro yakaipa. Mimwe midiki, nepo mimwe ichida kurapwa nekukurumidza.
| Mhedzisiro yedivi | Hunhu |
|---|---|
| Zvinhu zvekutaurira chiremba wako nekukasika | |
| Kusawirirana kwemuviri | Mapundu paganda, kuvaviwa, kuzvimba kwechiso, miromo, rurimi kana pahuro. |
| Kubuda ropa kusingajairika | Tsvina nhema kana kuti ine ropa, kurutsa kunoratidzika kunge kofi yakakuyiwa, weti tsvuku kana dema, mavanga madiki matsvuku kana epepuru paganda, mavanga asingawanzoitiki. |
| Kuchinja kwekurova kwemoyo | Kunzwa sekuti moyo wako uri kurova nekukurumidza kana kuti zvisina kurongeka, dzungu, kurwadziwa pachipfuva, kana kufema zvakaoma. |
| Utachiona | Fivha, dzihwa, kukosora, pahuro panorwadza, maronda asingapore, kurwadziwa pakuita weti. |
| Kushaya ropa | Kunzwa kuneta kana kushaya simba zvakanyanya, dzungu, musoro, kana kufema zvakaoma. |
| Udza chiremba wako kana zvichiramba zvichiitika kana kuti zvichikunetsa. | |
| Zvimwe zvirwere zvakajairika | Manyoka, musoro, kuneta, kurwadziwa kwetsandanyama, kuda kurutsa. |
Zvinhu zvekungwarira zvakanyanya panguva yekurapwa
Hutano hwemazino
Usati watanga kutora mushonga uyu, zvakanaka kuti uone chiremba wemazino woongororwa mazino ako. Chiremba wako anogona kukukurudzira kuti usavhiyiwe mazino zvakanyanya panguva yekurapwa. Uyewo, chengeta mazino ako akachena.
Kudzivirirwa kwezuva
Vamwe vanhu vanogona kunge vaine mukana wakawedzera wekuva nemamwe marudzi ekenza (kunyanya kenza yeganda) pavanenge vachinwa mushonga uyu. Saka, pfeka mbatya dzinofukidza zvakanaka uye shandisa mafuta ekudzivirira zuva paunenge uchibuda muzuva.
Kubata pamuviri nekuyamwisa
Izvi zvakakosha zvikuru: Dzivisa kubata pamuviri paunenge uchitora mushonga uyu uye kweinenge vhiki mushure mekurega mushonga. Mushonga uyu unogona kukonzera kukuvara kukuru kumwana asati aberekwa. Uyewo, dzivisa kuyamwisa paunenge uchitora mushonga uyu uye kwemavhiki maviri mushure mekurega mushonga.
Mharidzo Yekuenda Nayo Kumba
- Gara uchimedza kapusule yeacalabrutinib yese. Usaityore, kuipwanya, kana kuitsenga.
- Udza chiremba wako nezvemimwe mishonga yese, mavhitamini, uye zvimwe zvinovaka muviri zvauri kutora.
- Dzivisa kunwa mazambiringa nejusi remagrapefruit paunenge uchitora mushonga uyu.
- Kana ukaona kubuda ropa kusingawanzoitiki, mavanga, kana zviratidzo zvehutachiona (fivha, dzihwa), taurira chiremba wako nekukasika.
- Dzivisa kutora mushonga uyu panguva yekuzvitakura kana panguva yekuyamwisa. Taura nachiremba wako nezvenyaya iyi.
- Usamborega kutora mishonga kana kuchinja mwero wemushonga usina kurairwa nachiremba wako.
👩🏽⚕️ Mibvunzo yekuwedzera (Mibvunzo Inowanzo bvunzwa)
💬 Makapisiri eAcalabrutinib (Calquence) mushonga unodhura zvikuru unoshandiswa kurapa chirwere chipi?
Iri harisi piritsi rinowanzo shandiswa! Iri mushonga wegomarara unoshanda zvikuru uye une simba (Bruton Tyrosine Kinase - BTK Inhibitor) uchangobva kuwanikwa kune varwere vane gomarara rakadai se'Mantle Cell Lymphoma (MCL)' uye 'Chronic Lymphocytic Leukemia (CLL), idzo dziri gomarara reropa rine simba uye rakaipisisa rinokura mumasero machena eropa (B-cell), uye kune avo vasina kurapwa kumwe!
💬 Kana masero egomarara reropa achikura zvisingadzoreki, kutora mapiritsi aya (Calquence) kunoparadza sei gomarara?
Kuti masero ekenza yeropa apararire uye ararame, enzyme yakakosha inonzi 'BTK' inofanira kutumira meseji/chiratidzo! Kana mushonga uyu wangopinda mumuviri, unoenda kumuchina we'BTK' unopa/kuparadzira kenza uye unoivhara zvachose uye zvachose (Unosunga Zvisingadzoreki) uye unoivhara. Kana chiratidzo changorasika, masero ese ekenza anomira kupararira (Anodzivirira kuwanda kwemasero eB), kenza inofa uye murwere anopora.
💬 Ndezvipi njodzi dzinouraya uye migumisiro yakaipa iyo vanhu vanotora mushonga uyu wegomarara (Acalabrutinib) vanofanira kuziva?
Njodzi huru yemushonga uyu ndeyekuti unokanganisa hurongwa hwekugwamba kweropa, saka pasina chikonzero, murwere anogona kuva ne'ropa rinouraya' muuropi kana muura uye ofa kamwe kamwe (ndosaka mishonga inobvisa ropa/Warfarin ichirambidzwa)! Imwe njodzi huru ndeyekuti inopedza simba remuviri, saka kunyangwe hutachiona hudiki hunogona kukonzera murwere kupinda mukoma (Severe Infections). Inogonawo kukonzera chirwere chakakomba apo moyo unorova sekunge unopenga (Atrial Fibrillation).
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